Pavithra Dilakshini Dayananda

• Doctor of Philosophy
• Lecturer at University of Sri Jayewardenepura

With over 90% of infected proportions being asymptomatic to dengue, their possible contribution to silent transmission has generated much attention in epidemic and non-epidemic settings. The challenges in identifying the true asymptomatic representation, owing to no clinical symptoms, have limited scientific knowledge of the asymptomatic dengue, it...

Genetic variations in dengue virus (DENV) play a distinct role in epidemic emergence. The DENV 3′ UTR has become a recent interest in research. The objective of the study was to examine the genetic variation in the domain II, 3′ UTR region of human and mosquito-derived DENV. DENV-infected human sera were orally infected to laboratory reared Aedes a...

Aedes aegypti is the major vector of Dengue in Sri Lanka. Dengue virus is transmitted via blood feeding of vector mosquitoes. Blood is an essential component for the fecundity of mosquitoes and the knowledge on feeding behaviour of Ae. aegypti is important in dengue prevention measures. Therefore, the study was designed to identify the preferential...

Organophosphorus pesticides were reported to impair male reproductive function. Admire and lebaycid are two widely used insecticides in agriculture to combat agricultural pests. It is unclear whether these pesticides impact human spermatozoa. We investigated the effects of admire and lebaycid on morphology and functional aspects of human spermatozo...

Boiled aqueous extract of flowers (AEF) from Nyctanthes arbor-tristis L. are used in Sri Lankan traditional Ayruvedic Medicine to manage diabetes mellitus. AEF has widely been used as a folk medicine for the treatment of various ailments due to its therapeutic activity. However, little is known concerning therapeutic activity of the extract as well...

Dengue has become the major mosquito borne viral infection in Sri Lanka. Prevention and control of dengue relies heavily on surveillance and vector control. Since entomological and human-virological surveillance is less effective in predicting outbreaks, virological surveillance of dengue vectors has now become an area of interest. Potential of den...

This study examined the blood glucose lowering potential of the aqueous stem bark extract (ABE) of Sri Lankan endemic plant-Kokoona zeylanica (Family: Celestraceae). This was tested in normoglycaemic mice using three oral doses (1800, 2500 and 3000 mg/kg of body weight). The results show a moderate but dose dependant acute hypoglycaemic activity wi...