Paunescu Alina

University of Pitesti · Natural Science

This paper contributes to the ecotoxicological risk assessment of the Actellic 50 EC insecticide (with 50% pirimiphos-methyl as the active substance) tested on non-target organisms. The insecticide concentrations tested were the same for all organisms (0.1, 0.01, and 0.001 mgL−1 of Actellic 50 EC), with an exposure of 3–5–21 days for plants and 4–5...

The toxic action of the Actara 25 WG insecticide (it contains 25% thiamethoxam as an active substance) in non-lethal doses was studied in two species of aquatic organisms—the Prussian carp (Carassius gibelio) and the marsh frog (Pelophylax ridibundus)—at two thermal levels, 6–8 °C (low temperature) and 18–20 °C (room temperature), respectively. In...

The objective of this paper is to study the histological changes induced by Reldan 40EC in a dose of 0.01 ml chlorpyrifos/g body weight at the level of the lungs of the amphibian specimens Pelophylax ridibundus (Pallas, 1771). The insecticide was administrated by intraperitoneal injection (1 injection at 2 days in a scheme for 2 weeks). Highly dege...

The search of valuable natural compounds should be directed towards alternative vegetal resources, and to the re-discovery of underutilized plants. Belonging to the Plantaginaceae family, the hoary plantain (Plantago media L.) represents one of the lesser studied species from the Plantago genus. The literature study revealed the under-utilization o...

Haematological parameters reflect the condition of fish much faster than determining other parameters because they change extremely quickly as environmental conditions change, which is why they are widely used to describe the health of fish. Haematological and biochemical parameters can be used as standard laboratory tests to determine the effects...

In this study, we aimed to establish the influence of aqueous ferns extracts on the growth in length of the cucumber root. [...]

Esophageal cancer is still a health problem in middle income countries. The up-front treatment in localized disease is crucial for a better survival. Data from literature are in favor of a better response to radiotherapy of squamous histology. We have run a retrospective study to compare the response of histological subtypes of esophageal cancer to...

The aim of this study was to investigate the changes caused by the administration of ketoprofen to albino NMRI mice on some hematological, biochemical, and structural parameters. For this purpose, the mice were divided into two lots: a control batch and an experimental batch to which ketoprofen was administered subcutaneously at a dose of 10 mg/kg...

The aim of this study was to investigate the acute cardiovascular hemodynamic effects of administration of a fixed dose of 130 mg of caffeine versus placebo in a sample of healthy young adults (N = 32, sex ratio 1/1), who were successively placed in four distinct positions (orthostatic before ingestion, orthostatic, supine and Trendelenburg vertica...

Metallic nanoparticles represent an important area of research, as their unique properties can be tuned for the desired application. Several “green” methods were proposed for obtaining metallic nanoparticles, including phytosynthesis (using natural extracts) and radiation-assisted synthesis. The present work studies the differences in terms of biol...

The aim of this study was to determine the physiological and biochemical effects of chronic exposure to whole body vibration on the lipid metabolism in 20 healthy young adults (mean age 23.6±2.33 years). Each subject was exposed 3 times per week for a total of 6 weeks, in sessions of 15 minutes, at diagonal stimuli, at 25 Hz, on a vibration platfor...

The overuse of synthetic pesticide, a consequence of the rush to increase crop production, led to tremendous adverse effects, as they constitute a major pollutant for both soils and water, with a high toxicity towards humans and animals and, at the same time, led to development of pest resistance. In the last period, the researches were directed to...

The aim of the study is to quantify ventricular interactions by comparing tissue and spectral systolic echocardiographic parameters to allow the early identification of ventricular dysfunction. Clinical, paraclinical, electrocardiographic and echocardiographic evaluations were performed. Right ventricular hypertrophy was diagnosed in the M mode sub...

The aim of this study was to establish the influence of Dual Gold 960EC herbicide upon skinstructure in marsh frog (Pelophylax ridibundus). [...]

The aim of this study was to establish the influence of ferns extracts (Asplenium scolopendrium and Dryopteris filix-mas) [...]

The aim of the study is to quantify ventricular interactions by comparing tissue and spectral systolic echocardiographic parameters to allow the early identification of ventricular dysfunction. Clinical, paraclinical, electrocardiographic and echocardiographic evaluations were performed. Right ventricular hypertrophy was diagnosed in the M mode sub...

Knowledge of antibiotic resistance mechanisms is absolutely necessary to successfully fight against multi-resistant bacteria, the solutions to this issue being a direct consequence of understanding the mechanisms underlying its occurrence. Considering that in Romania more than 92.3% of patients have been receiving antimicrobial prophylaxis in surge...

Purpose of the study: echocardiographic evaluation of the form of degenerative aortic stenosis (DAS) with preserved ejection fraction (EF) and low transvalvular gradient, in order to formulate the indication of valvular prosthesis as early as possible; retrospective observational study that includes patients admitted or sent for ambulatory evaluati...

The objective of the study was to analyze the characteristics of the patients with preserved ejection fraction heart failure (HfpEF) who develop hyponatremia, in relationship with the diabetes mellitus (DM). The current study is an observational retrospective one, that included 36 patients(25 women, 11 men), aged 66.6 ± 3.1 years, hospitalized for...

Diabetic foot is a current public health problem and a late consequence of diabetes. Morbidity and mortality are significant, seriously affecting the patient's quality of life. Treatment of the diabetic foot is a long-lasting, highly resource-consumption process. Using negative pressure therapy leads to shorter hospitalization periods, better funct...

The effectiveness of pharmacological therapies is supported and guaranteed by medical protocols, which are the result of long-lasting experiments and scientific research, of course adapted to the level of competence and functional capacity of the healthcare provider. Besides pharmacological effectiveness, the therapeutic regimens should be evaluate...

This study used Attenuated Total Reflection Fourier Transform Infrared (ATR-FTIR) spectroscopy to provided detail information of the organic functional group of secondary metabolites, produced by ferns. The study showed ATR-FTIR spectra of nine fern species: Asplenium scolopendrium, Asplenium trichomanes, Asplenium trichomanes-ramosum, Athyrium fil...

The aetiology of ischemic vascular stroke (IVS) is various, the most common cause being cardioembolic, and anticoagulation treatment plays an essential role in the prevention of cerebral ischemic events. Atrial fibrillation (AF) is the pathological condition requiring long-term anticoagulant therapy for preventive purposes, both primary and seconda...

Antibiotherapy is the main determinant of Clostridium difficile infection due to the imbalance determined in the intestinal flora. Clostridium difficile infection can be considered a current public health problem, given the increased incidence, both as a nosocomial infection as well as at community level, by excessive, uncontrolled and unjustified...

The objective of the study is to screen for morphological, biochemical and histological changes induced by six widely used pesticides (Reldan 40EC, Actara 25WG, Tilt 250EC, Champion 50WG, Fusilade Forte, Dual Gold 960EC) in the amphibian species Pelophylax ridibundus (Pallas, 1771). Highly degenerative changes were observed in animals cultured at 2...

The present study shows the results of the chronic test in evaluating the response of lumbricidae under the action of different concentrations of Alleato 80WG. The earthworm samples were taken from a plot of land cultivated with maize. Survival, biomass and aluminum content bioaccumulated in earthworms have been analyzed. Five replicates were carri...

The thesis is devoted to the technical training of skilled archer. Following the analysis of literature was found structure factors that determine the effectiveness of exercise in the technique of competitive archery. The ways of improving the technical preparedness archer at the stage of basic training specialist associated with playing rhythmic,...

The aim of the study was to investigate the protective role of thiourea on the physiological, hematological, biochemical and histopathological parameters of Leuciscus cephalus exposed to sublethal concentration of Pendigan 330 EC herbicide. The animals were divided in four experimental groups (control, animals subjected to 1 ‰ thiourea, animals sub...

Using plants in treating some diseases has become a tradition, 'the nature's pharmacy' being an important source of therapy. At present, the medicinal plants properties are being reassessed due to progress made in chemical, pharmaceutical and clinical research of plants and due to forms obtained from vegetal products, but especially due to the adva...

In 1958, at the end of the restoration and at re-consecration of St. Elijah Church in Pitesti (Romania), in an improvised archive, were discovered some historical documents (testaments, petitions, notices, etc.) going back to 1841. With the occasion of the re-consecration, another document was signed by the priests involved. All these documents wer...

Data regarding antioxidant and antifungal properties of yarrow extracts and essential oils can be found on several other studies; however, due to the fact that the composition of the natural products varies from one geographical area to another and with the extraction procedure, the present study contributes to a better characterisation of natural...

The aim of this article is to study the in vitro bioaccumulation capacity of lead in four autochthnous pteridophyte species: Asplenium scolopendrium (As), Asplenium trichomanes-ramosum (At), Cystopteris fragilis (Cf), Polypodium vulgare (Pv), with a view to use them inphytoremediationprocesses. The polyphenol and flavonoid amounts determined in the...

The main objective of this study is to see how the royal insecticide influences the energetic metabolism, the breathing rhythm, the blood sugar and the number of red blood cells at the Prussian carp individuals. Experimental samples were subjected to under-lethal concentrations of 0.00125, 0.0025 and 0.005 ml/l royal insecticide from 24 to 336 hour...

In our researches we have determined the variation of certain physiological indexes, such as the oxygen consume, the breathing rhythm, the glycaemia and the number of red blood cells under the action of Coragen insecticide on Carassius auratus gibelio Bloch. Under the action of Coragen, we have registered significant changes in the oxygen consume,...

In the present paper it was investigated the protective effect of malvidin on the hematological, biochemical and histopathological parameters of marsh frog (Pelophylax ridibundus) exposed to sublethal concentration of Roundup® herbicide. The animals were divided in 3 experimental groups: lot of control individuals, second lot containing animals whi...

The aim of this paper was to test the antioxidant activity, polyphenols content and antimicrobial activity of crude extracts obtained from leaves of pteridophyte species commonly found in Romania. The ORAC (Oxygen Radical Absorbance Capacity) of the investigated ferns varied between 421.90 μmol TE (Trolox equivalents/g FW (fresh weight) in Dryopter...

Histological and histochemical alterations in the liver of the frog Rana ridibunda induced by the action of the insecticide Reldan 40EC (chlorpyrifos-methil) were investigated. The animals used in the experiment were treated with 0.01 ml/g body weight Reldan 40EC and kept at 4-6ºC, respectively at 22-24ºC. The toxic was administrated by intraperito...

Talstar insecticide is labeled for numerous bugs and many other household pests and lawn pests. Bifenthrin is highly toxic to fish and aquatic arthropods. Bifenhrin LC50 values range from 0.0038 to17.8 μg/L and is only slightly toxic to both waterfowl and upland game birds (LD50 values range from 1.800 mg/kg to > 2.150 mg/kg). Bifenthrin had no eff...

Adult male and female frogs Rana ridibunda were exposed to 0.125x10-3mg Champion 50WP/g body weightadministrated by intraperitoneal injection, 1 injection at 2 days in a scheme of 3 weeks. The animals were kept at 4-6°C,respectively at 22-24°C in tap water tank. At the end of the experiment we observe large quantities of Pearls reagentmaterial in K...

Aim of this study is to demonstrate the hepatoprotective role of grape seed oil and Cynara scolymus leaf extract. This experiment lasted for 12 days performed on male and female rabbit. The animals were intoxicated in the latest day of experiment (day 12th) with CCl4 in a dose of 30μl/100g body weight and a group of them was treated for 12 days wit...

The experimental model of the tetrachloride intoxication in the frog was used in order to study, at the histological level, the lesions of the hepatocytes and of hepatic sinusoid cells, caused by this toxic. After the treatment, a slight accumulation of the fibrous structures of collagen was noted, accompanied by accumulation of lipofuscine in the...

This study was carried out to analyze the effect of sublethal and lethal concentration (0.1mg/l, 0.2mg/l, 0.4mg/l, 0.8mg/l and 1.6mg/l) of Mospilan 20SG insecticide upon some physiological parameters (oxygen consumption, breathing frequency) and gill histopathology on prussian carp (Carassius auratus gibelio Bloch). The acute and subacute toxicity...

In our experiments we followed the histological and physiological modifications induced by the action of the insecticide Carbetox at the skin and liver level of Rana Ridibunda. Carbetox is an organophosphate insecticide commonly used to control mosquitos and other flying insects. The animals used in the experiment were divided in three experimental...

Noţiunea de substanţă toxică reprezintă conceptul etiologic care defineşte obiectul de studiu al toxicologiei, în general, şi al toxicologiei clinice, în special. Prin substanţă toxică se înţelege orice compus chimic exogen care, pătruns în organism pe diferite căi, provoacă alterări structurale şi funcţionale la diferite niveluri de organizare a m...