
Paulo BonanFederal University of Paraíba | UFPB · Departamento de Clínica e Odontologia Social
Paulo Bonan
PhD, Stomatopathology
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270
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Introduction
Additional affiliations
July 2013 - present
July 2011 - present
August 2004 - March 2011
Publications
Publications (270)
Small cell osteosarcoma (SCOS) is a rare variant of conventional osteosarcoma, characterized by tumor cells of small size and uniform morphology, which can lead to diagnostic confusion with other small cell tumors, requiring a detailed diagnostic approach. The manifestation in a child adds a degree of complexity, as the management of malignant tumo...
Objective: To reveal the capabilities of the Teleinterconsulting application in Stomatology, shedding light on how this tool operates within our own experience.
Material and Methods: This observational and cross-sectional study was carried out using data obtained from the pilot study of the Teleinterconsulta application in Stomatology in Paraíba, B...
Objetivo: Descrever o desenvolvimento de uma solução tecnológica para o rastreio do câncer de boca. Métodos: Esta pesquisa de desenvolvimento tecnológico e inovação foi conduzida seguindo o método Design Centrado no Usuário (DCU) em quatro etapas, nomeadamente: I) Observação; II) Idealização; III) Prototipação e IV) Testagem. Resultados: A ferramen...
Objective
To analyze the characteristics of a series of oral reactions to injectable soft tissue fillers.
Materials and Methods
Cases diagnosed as oral reactions to injectable soft tissue fillers were selected from eight Pathology laboratories. Information was retrieved from the laboratory charts and from the review of the hematoxylin and eosin‐st...
Objective
Development and evaluation of a mobile application for remote monitoring and guidance of pediatric patients diagnosed with cleft lip and/or palate (CL ± P) and their caregivers.
Design
This is a pilot cross-sectional, applied, and quantitative study.
Setting
The study was conducted in two tertiary care treatment centers in Brazil.
Part...
Introduction
Cleft lip and/or palate (CL+/-P) is a congenital malformation affecting the lip and palate, requiring long-term treatment due to potential associated complications. For this reason, it is important for the patient to be continuously monitored and followed for health promotion and prevention, as well as improving the quality of life. Th...
The use of conventional chemotherapy in conjunction with targeted and immunotherapy drugs has emerged as an option to limit the severity of side effects in patients diagnosed with head and neck cancer (HNC), particularly oropharyngeal cancer (OPC). OPC prevalence has increased exponentially in the past 30 years due to the prevalence of human papill...
A esporotricose é uma infecção fúngica comum que apresenta várias manifestações clínicas, incluindo formas cutâneas, mucosas, osteoarticulares, sistêmicas e imunorreativas. Sua ocorrência na cavidade oral é incomum, sendo mais frequentemente observada em pacientes imunocomprometidos e manifestando-se como lesões ulcerativas. No presente caso, uma p...
Objective
To report nine cases of pediatric patients with Acute Lymphoid Leukemia (ALL) or Acute Myeloid Leukemia who developed severe oral mucositis (SOM) at the first week of chemotherapy.
Material and Methods
The cases were selected from a sample of 105 children followed for 10 consecutive weeks. Hematological and personal data were obtained fr...
Introduction. Oral lymphatic malformations are uncommon lesions. This study assessed the clinicopathological and sociodemographic features of oral lymphatic malformations in a Brazilian oral pathology service. Methods. Between 2000 and 2021, all oral lymphatic malformations diagnosed in a single oral pathology service were selected for the study. C...
O câncer de boca é um importante problema de saúde pública, sendo responsável por 3% do total de cânceres no mundo e a 15ª causa mortis mais frequente. Apesar das lesões iniciais serem facilmente detectáveis, apenas 6,25% dos casos de Carcinoma Espinocelular, principal tipo de câncer de boca, são detectados em estágio I, significando atraso no trat...
Background:
Teledentistry is considered a good tool in the diagnostic process. In oral medicine, there is a low number of trained professionals and dentists have difficulty in diagnosing and treating oral lesions.
Objective:
We aimed to perform a cross-sectional evaluation based on the mobile application for oral diagnosis using a mobile applica...
As estratégias digitais de educação em saúde bucal são indispensáveis para promover o autocuidado. O câncer bucal afeta, principalmente, adultos e idosos e está relacionado a morbimortalidade elevada. O objetivo deste estudo foi desenvolver e validar o conteúdo de um infográfico animado, para idosos sobre câncer bucal. Realizou-se um estudo metodol...
Objective:
Evaluate the effect of a multidrug solution, adopted by a referral hospital for cancer to control and treat chemotherapy-induced oral mucositis in rats.
Methods:
Oral mucositis (OM) was induced by 5-Fluorouracil (5-FU), and the animals were treated with saline (n = 8, G1), 0.12% chlorhexidine (n = 8, G2); and multidrug solution (n = 8...
Objective:
The antimicrobial effect of prosthetic materials treated with chitosan was systematically reviewed.
Methods:
The searches were carried out on PubMed/Medline, Scopus, ISI Web of Science, LILACS, Embase, and Open Grey with searches performed in March 2022. Selection of in vitro studies, data extraction and risk of bias analysis were per...
Head and neck squamous cell carcinomas (HNSCC) are a heterogeneous group of malignancies which have shown exponential incidence in the last two decades especially due to human papillomavirus (HPV) infection. The HPV family comprises more than 100 types of viruses with HPV16 and HPV18 being the most prevalent strains in HNSCC. Literature data reveal...
Statement of problem
Stone casts are subject to contamination, but whether disinfectants incorporated into the stone are effective is unclear.
Purpose
The purpose of this in vitro study was to evaluate the antimicrobial activity and the mechanical and surface properties of self-disinfecting gypsum (SDG) and gypsum mixed with 2% chlorhexidine (GCHX...
O objetivo do trabalho foi descrever a experiência dos discentes do curso de Odontologia, os quais por meio do uso de metodologias ativas elaboraram e apresentaram uma live sobre Teleodontologia durante o componente curricular Tecnologias de Informação e Comunicação em Odontologia (TICO) na Universidade Federal da Paraíba (UFPB). Trata-se de um est...
Herpes zoster (HZ) is a viral infection caused by reactivation of the varicella zoster virus, latent in nerve cells, after an episode of varicella. A 62-year-old female patient complained of lesions on the tongue and lower lip with painful symptoms. Extraoral physical examination revealed skin crusts on mental, zygomatic, and labial commissure regi...
The purpose of this work is to report the usefulness of fine needle aspiration biopsy in a 17-year-old female patient with swelling in the left submandibular region. On extraoral examination, skin eruptions in the lower limbs and a nodule on the left submandibular region were observed. The cervical nodule was painless, measuring 1 cm × 1 cm, with a...
We report an uncommon presentation of oral syphilis in a male patient, 29 years old with a 2-month mouth ulcer. Clinical examination showed right submandibular lymphadenopathy and a painless ulcer located on the right labial commissure. Serology was requested for syphilis (VDRL) and HIV—both nonreactive—and a complete blood count that showed no cha...
Objectives
Evaluate the teaching of oral medicine (OM) and oral pathology (OP) in dentistry courses in Brazil, analyzing their pedagogical matrices.
Study Design
This is an exploratory study of document analysis. The institutions investigated were collected on the website of the Ministry of Education of Brazil (www.portal.mec.gov.br). Accessing we...
Background:
The likelihood of infection with SARS-COV-2 (COVID-19) in the dental office is considered high.
Objectives:
Assessing the impact of the COVID-19 on dental practices and anxiety levels in risk group Brazilian dentists.
Methods:
A cross-sectional study was performed using an online questionnaire. The data obtained were analyzed using...
Objective: This article aims to present a case report of a patient with Juvenile Idiopathic Arthritis (JIA), with orofacial sequelae and impairment of the temporomandibular joint (TMJ). Case report: Patient HMM, 26 years old, female, Caucasian, attended the Occlusion, Temporomandibular Disorders, and Orofacial Pain Clinic service at UFPB with a com...
Oral mucositis (OM) is the most common local adverse event of chemotherapy treatment and leads to a debilitating condition from the patient’s perspective. The aim of this study is to report nine cases of severe OM over 10 weeks after initiating chemotherapy in pediatric patients with leukemia. All patients showed changes in normality of hematologic...
Introduction: Simultaneously to the onset of Coronavirus disease (COVID-19), many skin diseases have been diagnosed, including systemic lupus, lichen planus and psoriasis. The disruption of selftolerance and activation of autoimmune responses by SARS-CoV-2 cross-reactivity with host cells accounts for this coincidence.
Objectives: To evaluate the n...
Herpetic dermatitis and oral recurrent herpes (ORH) are among the most common human infections. Antiviral drugs such as acyclovir (ACV) are used in the standard treatment for ORH. Despite its therapeutic efficacy, ACV is continuously and repetitively administered in high doses. In this sense, the development of controlled release drug delivery syst...
How to cite: Damascena LCL, Bezerra PMM, Santos FG, Lucena NNN, Vieira TI, Viana Filho JMC, et al. Impact of COVID-19 on oral healthcare for oncopediatric patients: the setting in a reference hospital in Northeast Brazil. Pesqui Bras ABSTRACT Objective: To describe the impact of the COVID-19 pandemic on dental care provided to pediatric cancer pati...
Background:
The changes in dental care in the face of the COVID-19 pandemic resulted in the need for greater financial investment by dentists in biosafety measures and increase in the costs of dental consultations.
Objective:
To evaluate the economic impact of the COVID-19 pandemic on dental practices in private clinics in Brazil.
Methods:
A c...
Background:
Oral cancer represents a worldwide public health problem, being among the most prevalent, associated with high morbidity and mortality rates. This systematic review aimed to review the causes of the delayed diagnosis of oral cancer mainly in the elderly, in developed and developing countries.
Material and methods:
Search strategy was...
Coronavirus disease 2019 (COVID-19) protocols has reduced primary and secondary health care for other diseases, such as leishmaniasis, a parasitic, endemic, chronic and persistent disease in Brazil. To ascertain this, we compared the number of leishmaniasis cases diagnosed before and after the COVID-19 pandemic. In 5 regions of Brazil, there was an...
Almost 30% of oral clefts are associated with other structural abnormalities. However, little is known on orofacial characteristics related to these cases since they are not systematically reported. To close this gap, we developed a collaborative learning approach supported by an interprofessional team aiming to systematically describe oral finding...
Background:
This study aimed to evaluate the perception of self-regulated learning of Brazilian undergraduate dental students during the COVID-19 pandemic.
Material and methods:
A nationwide cross-sectional survey was conducted. Data were collected in 2020, through an anonymous self-administered virtual questionnaire, which comprised an initial...
This research aimed to evaluate the reliability of methods using a new graphic template to evaluate alveolar bone graft in cleft lip palate on radiographs. The sample consisted of 30 radiographs of individuals with bone grafts that were analyzed by two raters using SWAG and Chelsea, alveolar bone graft rating methods. The images were analyzed in Po...
O objetivo deste estudo foi apresentar os desafios relacionados ao cumprimento dos novos protocolos de biossegurança, na perspectiva do retorno das atividades presenciais nas instituições de ensino superior em Odontologia, no cenário da pandemia da COVID-19. Tratou-se de um estudo qualitativo, de caráter exploratório, ancorado na técnica de pesquis...
Objective
This work aimed at producing silica-blow-spun nanofibers containing silver nanoparticles (SiO2/Ag) and investigating the effect of their incorporation in different proportions, with or without pre-treatment with a silane coupling agent, on the mechanical, physicochemical, and biological properties of a commercial composite low-viscosity b...
Background:
The COVID-19 pandemic has raised challenges in adapting to teaching and learning methods in dental education.
Objective:
This study aimed to evaluate the impact of the COVID-19 pandemic on the academic activities of undergraduate (UDG) and graduate (GD) dental students in Brazil. Additionally, students' perceptions and attitudes towa...
Herpes Zoster (HZ) é uma infecção aguda causada pelo vírus varicela-zoster, quando ocorre reativação do mesmo que está latente em células nervosas de indivíduos que tiveram varicela. O mecanismo da reativação viral ainda é desconhecido, porém acredita-se que esteja relacionado com algum tipo de deficiência na imunidade. A doença afeta mais comument...
Objectives
Evaluate the relation of rheumatoid arthritis (RA) and bone changes in the temporomandibular joint diagnosed by cone-beam computed tomography (CBCT).
Materials and methods
This systematic review and meta-analysis were recorded in the PROSPERO database, using the CRD42020153246 protocol. The electronic searches were performed in the foll...
This study aimed to produce a Poloxamer 407/Chitosan polymeric system for the controlled release of α-TOC and evaluate its biological properties using normal oral keratinocytes. The production of the polymeric controlled release system involved loading of α-TOC and micellization of the isotropic P407 phase with subsequent encapsulation with chitosa...
This work aims to investigate the association between geriatric depression and oral self-perception, assessing functional scales, socioeconomic determinants, and normative oral conditions. The study was based on an inductive approach, with statistical procedures and descriptive technique using direct observation with 250 elders enrolled at the Refe...
Este trabalho analisou o perfil socioeconômico e o conhecimento sobre saúde bucal das gestantes de alto risco atendidas no Hospital Universitário Lauro Wanderley (HULW) da Universidade Federal da Paraíba (UFPB). Trata-se de um estudo observacional, descritivo, transversal e de natureza quantitativa, o qual utilizou o programa Epi Info versão 7.2.4...
Aim
This study aimed to evaluate the time to diagnosis of pediatric cancer and associated comorbidities during cancer therapy.
Subject and Methods
This was a prospective observational study with a 20-month follow-up of 146 pediatric patients diagnosed with cancer and treated in northeastern Brazil.
Results
The mean age of the participants was 8.2...
Kawasaki disease (KD) is a vasculitis with predilection for coronary arteries. Due to a lack of reliable confirmatory laboratory tests, the diagnosis of KD is based on a characteristic pattern of clinical findings that appear in a typical temporal sequence. The diagnostic criteria have been periodically modified and the American Heart Association h...
Head and neck squamous cell carcinoma (HNSCC), a prevalent cancer worldwide, has a high incidence of loco-regional dissemination, frequent recurrence, and lower 5-year survival rates. Current gold standard treatments for advanced HNSCC rely primarily on radiotherapy and chemotherapy but with limited efficacy and significant side effects. In this st...
Aim
It was analyzed the efficacy of mouthwash and spray containing essential oil (EO) of Cinnamomum zeylanicum Blume for the treatment of oral candidiasis.
Methods and results
A randomized, controlled, and blinded clinical trial was conducted with 36 individuals (probabilistic sample) with oral candidiasis who were divided into two treatment group...
Non-plaque-induced lesions may occur on the gingiva as medical disorders or manifestations of systemic conditions. Scabies is a parasitic infection caused by Sarcoptes scabiei. Here, we present the first case of oral scabies reported in the literature located on the gingiva in a 43-year-old woman. She was admitted to the hospital complaining of an...
The aim of this study was to develop polymeric nanofibers for controlled administration of Amphotericin B (AmpB), using the solution centrifugation technique, characterizing its microstructural and physical properties, release rate, and activity against Leishmania and Candida species. The core-shell nanofibers incorporated with AmpB were synthesize...
Objective
This study evaluates the mechanical, physical, and biological properties of resin‐based dental cement (RelyX ARC, 3M ESPE) incorporated with hydroxyapatite and 45S5 bioactive glass.
Methods
Bioactive glass (45S5) and hydroxyapatite (HA) were added to cement in different proportions (10 wt% and 20 wt%). Three‐point flexural strength, micr...
During the last weeks, we are facing a global pandemic which affects the general population and health care system. Observing COVID-19 care, hospitals and health care services are focusing their attention on COVID-19 combat. Considering this emergency, structural and logistic impacts over health services are perceived evidently and conventional rou...
Head and neck cancer (HNC) is a complex and heterogeneous disease associated with high mortality and morbidity worldwide. Standard therapeutic management of advanced HNC, which is based on radiotherapy often combined with chemotherapy, has been hampered by severe long-term side effects. To overcome these side effects, tumor-selective nanoparticles...
Objective: To verify the prevalence of burnout syndrome and to associate it with temporomandibular dysfunction (TMD) in a sample of dental students from a public university. Study Design: A cross-sectional study with a sample of 108 volunteers. Data was collected by evaluating the signs and symptoms of TMD using the Fonseca index (DMF) and Research...
Objective: To evaluate the quality of oral cancer information in Portuguese (Brazilian) on Google, YouTube, and Instagram. Study Design: The first 100 links of each platform characterized the initial sample. The sites and Instagram were evaluated using the JAMA criteria, the DISCERN instrument, and the Flesch intelligibility index. From the sites,...
A 11-year-old male patient reported a "hardness in the cheek." In the anamnesis, a palpable hard nodular lesion was observed in the jugal mucosa, slightly mobile, painless, and of unknown evolution. In the ectoscopic examination, nothing was initially identified. The oroscopic examination revealed a sessile nodule, covered by healthy mucosa, asympt...
A 33-year-old man sought treatment after presenting with an ulcerated lesion on the lower lip, symptomatic and associated with a history of fever and 1 year of evolution. The echoscopic examination showed evidence of solar lentigines on the face and symptomatic lymphadenopathy in the right submandibular region. Ulcerative lesions on the lower lip (...
A 14-year-old patient presented with a complaint of “left ear lump,” associated with a history of fever and 1 month of evolution, and not responding to broad spectrum antimicrobials. At the echoscopic examination, there was evidence of a nodular lesion in the left parietal region, sessile, with a fibroelastic consistency. Initially, the hypotheses...
AbstractBackground:Fungal infections associated with the use of dentures, like denture stomatitis, are difficult to preventand treat. This in situ study aimed to investigate the efficacy of cinnamaldehyde for the disinfection of completeremovable dentures, and the effect on the physical and mechanical properties (Vickers microhardness, color, andsu...
Abstract Background Fungal infections associated with the use of dentures, like denture stomatitis, are difficult to prevent and treat. This in situ study aimed to investigate the efficacy of cinnamaldehyde for the disinfection of complete removable dentures, and the effect on the physical and mechanical properties (Vickers microhardness, color, an...
O tumor de células granulares (TCG) é uma neoplasia benigna de origem neural incomum que acomete tecidos moles. Possui predileção pelo sexo feminino entre as 4ª e 6ª décadas de vida e apresenta-se clinicamente como um nódulo submucoso indolor em dorso de língua. O tratamento de escolha é a remoção total da lesão, apresentando um bom prognóstico, co...
Objective
To compare the effectiveness and acceptability of a newly developed pediatric sialometer as an alternative to the conventional spitting method.
Methods
A clinical study was carried out with healthy children (G1; n = 30) and oncological children (G2; n = 30). A newly developed pediatric sialometer was compared to the traditional spitting...
The aim of this study is to evaluate salivary and microbiological parameters of pediatric oncological patients and their correlation with severe oral mucositis (SOM).This study aims to evaluate the salivary parameters and cariogenic microbiota of pediatric oncological patients and their correlation with severe oral mucositis (SOM). A preliminary lo...
Introdução: O cisto ósseo simples é uma lesão benigna intra-óssea considerada um pseudocisto, de etiologia incerta, crescimento lento, radiograficamente radiolúcida e de tratamento simples. Porém, pode fazer diagnóstico diferencial com outras lesões mais agressivas, e a ausência ou tênue presença de uma cápsula cística prejudica seu diagnóstico his...
The in vitro bioactivity and in vivo bone neoformation in critical-size bone defects of a glass-ceramic material containing strontium ions (Sr²⁺) were evaluated in the present study as well as the antimicrobial effect against oral pathogens. A glass-ceramic bioactive material in powder (CP), based on the composition of S53P4 bioactive glass, was pr...
Due to the COVID-19 pandemic crisis, many dental schools and instructors are rethinking the way they teach and interact with students. New perspectives regarding a change in face-to-face activities, social isolation and the reformulation of clinical activities result in a transition toward e-learning and e-teaching processes. In this review, we dis...
The Actinomycosis is a rare infection caused by microorganisms of the genus Actinomyces. Its clinical presentation may resemble or mask other infectious processes, which makes the diagnosis complex and compromises therapeutic success. The aim of this work is to report a case of osteomyelitis caused by a bacterial infection, discuss the clinical man...