Paulina Ramírez Neria

Asociacion para Evitar la Ceguera en México (APEC) · Department of Ophthalmology

Disclosure: C. Clapp: None. C.D. Núñez-Amaro: None. M. López: None. E. Adán-Castro: None. M. Robles Osorio: None. R. García-Franco: None. M. García-Roa: None. Y. Villalpando: None. P. Ramírez-Neria: None. N. Pineiro: None. J.F. Rubio-Mijangos: None. J. Sánchez: None. G. Ramirez-Hernandez: None. L. Siqueiros-Márquez: None. N. Díaz-Lezama: None. E. L...

Background/Objective The prokinetic levosulpiride elevates vasoinhibin levels in the vitreous of patients with proliferative diabetic retinopathy (PDR) suggesting clinical benefits due to the anti-vasopermeability and anti-angiogenic properties of vasoinhibin. We investigated the biological activity of levosulpiride in centre-involving diabetic mac...

Purpose: To analyze the macular ganglion cell-inner plexiform and retinal nerve fiber layer thicknesses after vitrectomy with the inverted flap technique for idiopathic macular holes. Methods: A prospective study was conducted on 28 eyes treated with surgery for idiopathic macular holes. The inverted internal limiting membrane flap technique ass...

This study aimed to compare clinical efficacy of retinal laser photocoagulation using a 577-nm multi-spot laser with pulses of 20 ms versus conventional 532-nm single-spot laser treatment with pulses of 100 ms, on the same patient with proliferative diabetic retinopathy (PDR) during 6-weeks follow-up. We included 46 eyes of patients treated at the...

Objetivo: Comparar el efecto de la insulina tópica y del hialuronato sódico en el cierre del defecto epitelial producido por el desbridamiento corneal transquirúrgico durante la vitrectomía vía pars plana en diabéticos. Método:: Ensayo clínico controlado. Los pacientes fueron aleatorizados a uno de tres grupos de tratamiento: hialuronato sódico tó...

Purpose The purpose of the study is to describe visual and anatomic outcomes of 5774nm micropulse laser photocoagulation in eyes with either treatment-naïve or refractory diabetic macular edema (DME) at 3 months. Methods This was a prospective case series that recruited 23 consecutive patients (33 eyes) with center-involved DME that was either tre...

Objective: To determine normal macular thickness values in a healthy Mexican population and its variation by age and gender using Huvitz spectral-domain optical coherence tomography (HOCT-1F). Methods: This cross-sectional study included 211 consecutive eyes from clinically normal subjects (66 men, 145 women) between October 2018 and December 2018,...

Purpose This work examines the relationship between first- and third-month anatomical and visual response with antivascular endothelial growth factor for diabetic macular edema. Methods We prospectively evaluated 58 eyes with center-involved diabetic macular edema. Response was categorized upon the anatomical status after 3 monthly doses based on...

Purpose: High circulating levels of the hormone prolactin (PRL) protect against experimental diabetic retinopathy (DR) due to the retinal accumulation of vasoinhibin, a PRL fragment that inhibits blood vessel permeability and growth. A phase 2 clinical trial is investigating a new therapy for DR based on elevating serum PRL levels with levosulpiri...

Appropriate medical management can be an alternative in those patients with submacular cysticercosis in whom achieving good visual outcome with vitreoretinal surgery is not possible. We report the case of a 25-year-old female who presented complaining of blurred vision in her left eye associated with photopsias and metamorphopsias of 3 months durat...

Endogenous endophthalmitis is a disease that potentially threatens vision. It is produced by the haematogenous spread of microorganisms from a septic focus. It is a rare condition that is related to debilitating diseases, immunosuppression states, and invasive procedures. Endogenous endophthalmitis during pregnancy is even rarer, and has become a c...

PRéCIS:: Intraocular pressure measurement differences with Goldmann applanation tonometry and Dynamic contour tonometry are affected by atmospheric pressure inside a hyperbaric chamber. Purpose: To compare intraocular pressure measurements obtained with Goldmann applanation tonometry (GAT) and Dynamic contour tonometry (DCT) in 22 normal individu...

Resumen La endoftalmitis endógena es una enfermedad que amenaza potencialmente la visión en los pacientes que la presentan. Es producida por la diseminación hematógena de microorganismos desde un foco séptico y se trata de una entidad poco frecuente que se relaciona con enfermedades debilitantes, estados de inmunosupresión y procedimientos invasivo...

A 35-year-old woman with progressive decrease of vision in both eyes and with no other associated symptoms, manifested as the only antecedent, the death of her brother due to amyloidosis. The visual acuity was counting fingers at 30 cm in the right eye and 20/70 in the left eye. In ophthalmoscopy of the right eye, a white, homogeneous vitreous, tha...

Introduction: Macular hemorrhages result in a sudden and profound loss of vision. The primary treatment modalities include observation, intravitreal injection of antiangiogenic drugs, neodymium-doped yttrium aluminum garnet hialoidotomy, intravitreal injection of gas with or without tissue plasminogen activator, as monotherapy or combined with sur...

Resumen Mujer de 35 años con disminución progresiva de visión en ambos ojos sin otros síntomas asociados manifestó como único antecedente la muerte de su hermano por amiloidosis. La agudeza visual fue de cuenta dedos a 30 centímetros en el ojo derecho y 20/70 en el ojo izquierdo. En la oftalmoscopia del ojo derecho se observó un vítreo blanco, homo...

Purpose This is a case report of a male patient who suffered a high-voltage electrical burn and presented with bilateral pigmentary retinopathy. Methods A 40-year-old man presented with bilateral vision loss following a high-voltage electrical injury sustained 10 years earlier. Family history, ocular history, and anterior segment evaluation were u...

Background: Determining the precise location of intraocular foreign bodies is crucial for the management of patients with open-globe injury. Computed tomography is the most common method for detecting intraocular foreign bodies in the posterior segment. In this article, we describe three cases of open-globe injury with different types of intraocul...

We report the case of a 2-month-old male infant who was brought in for a routine visual examination. Fundus examination revealed generalized hypopigmentation of the fundus in both eyes and a small rounded pigmented choroidal lesion in his left eye of approximately two disc diameters near the temporal inferior vascular arcade. Ultrasonography showed...

Background Retinopathy of prematurity (ROP), the primary cause of blindness in children, is a potential complication for 7.7% of live births in Mexico. Given that less than one-third of all neonatal intensive care units follow Mexican National ROP guidelines, there have been few reports regarding the incidences of types 1 and 2 ROP. Methods This w...

We report a 1 year old female who unusually presented with retinal hemorrhages, neovascularization, subtotal serous retinal detachment and no exudation in one eye at her first visit, and found to have a classic "Coats disease". A 1 year old female presented with a history of exodeviation of one eye, fundoscopic findings showed retinal hemorrhages,...

Purpose: To describe the anatomic and functional outcomes in patients with chronic kidney disease who underwent pars plana vitrectomy for proliferative diabetic retinopathy. Methods: We retrospectively reviewed the medical records of patients with chronic kidney disease who underwent 25-gauge vitrectomy for diabetic vitreous hemorrhage and/or tract...

Background: Diabetic retinopathy (DR) and diabetic macular edema (DME) are potentially blinding, microvascular retinal diseases in people with diabetes mellitus. Preclinical studies support a protective role of the hormone prolactin due to its ocular incorporation and conversion to vasoinhibins, a family of prolactin fragments that inhibit ischemia...

Acute pulmonary embolism (APE) is considered a cardiovascular emergency and is one of the most important causes of morbidity and mortality in hospitalized patients. Pulmonary embolism diagnosis has to be made early in the course of the disease and its management installed immediately. Pulmonary embolism management includes hemodynamic support, anti...

Acute pulmonary embolism (APE) is considered a cardiovascular emergency and is one of the most important causes of morbidity and mortality in hospitalized patients. Pulmonary embolism diagnosis has to be made early in the course of the disease and its management installed immediately. Pulmonary embolism management includes hemodynamic support, anti...

Pulmonary arterial hypertension (PAH) is a chronic and progressive disease with a poor prognosis if left untreated. Pathophysiological alterations in this disease lead to vasoconstriction, endothelial and smooth muscle cell proliferation, and in situ thrombosis. Endothelin-1 (one of the most potent vasconstrictors known), has been shown to be incre...

PURPOSE: Eisenmenger’s syndrome (ES) refers to the most advanced form of pulmonary arterial hypertension(PAH) associated with congenital unrepaired systemic-to-pulmonary cardiac shunts(CHD). In contrast to other subgroups of PAH, patients with ES are known to exhibit a far better survival. However, we believe this changes significantly once clinica...

PURPOSE: Uric acid (UA) has been proposed as a mortality predictor and strong marker for severity in patients with pulmonary arterial hypertension(PAH). Nevertheless, its role in the pediatric population has not been entirely elucidated. We aimed to evaluate which parameters predict high UA levels, and its role as a mortality predictor in a pediatr...