Paulina Fuentes

• MD Master of Science
• Medical Doctor at Hospital Clínico Regional Dr Guillermo Grant Benavente

Background: Adaptation of existing guidelines can be an efficient way to develop contextualized recommendations. Transparent reporting of the adaptation approach can support the transparency and usability of the adapted guidelines. Objective: To develop an extension of the RIGHT (Reporting Items for practice Guidelines in HealThcare) statement for...

Introduction and hypothesis Recommendations for preventing and diagnosing recurrent urinary tract infection (UTI) tend to vary between clinical practice guidelines (CPGs) because of low-quality scientific evidence, potentially leading to practice variation and suboptimal care. We assessed the quality of existing CPGs for recurrent UTI. Methods A s...

Background Early enteral nutrition support (within 48 hours of admission or injury) is frequently recommended for the management of patients in intensive care units (ICU). Early enteral nutrition is recommended in many clinical practice guidelines, although there appears to be a lack of evidence for its use and benefit. Objectives To evaluate th...

Background: Early enteral nutrition support (within 48 hours of admission or injury) is frequently recommended for the management of patients in intensive care units (ICU). Early enteral nutrition is recommended in many clinical practice guidelines, although there appears to be a lack of evidence for its use and benefit. Objectives: To evaluate...

Introduction The adaptation of guidelines is an increasingly used methodology for the efficient development of contextualised recommendations. Nevertheless, there is no specific reporting guidance. The essential Reporting Items of Practice Guidelines in Healthcare (RIGHT) statement could be useful for reporting adapted guidelines, but it does not a...

Significant international and cross-border migration has led to a growing availability of migrant healthcare guidelines (MHGs), which we systematically reviewed for quality. PubMed, MEDLINE, CINHAL, PsychINFO and guideline developer/guideline databases were searched for MHGs published 2006–2016. Three independent reviewers assessed eligible MHGs us...

Background Red blood cell (RBC) transfusions are essential in health care. The quality of recommendations included in clinical practice guidelines (CPG), regarding this intervention, has not been systematically evaluated. This paper systematically assessed CPGs for RBC‐transfusion, to appraise their methodological quality, to explore changes in qua...

Background: (18)F-florbetapir uptake by brain tissue measured by positron emission tomography (PET) is accepted by regulatory agencies like the Food and Drug Administration (FDA) and the European Medicine Agencies (EMA) for assessing amyloid load in people with dementia. Its added value is mainly demonstrated by excluding Alzheimer's pathology in...

Background: (18)F-flutemetamol uptake by brain tissue, measured by positron emission tomography (PET), is accepted by regulatory agencies like the Food and Drug Administration (FDA) and the European Medicine Agencies (EMA) for assessing amyloid load in people with dementia. Its added value is mainly demonstrated by excluding Alzheimer's pathology...

Background: (18)F-florbetaben uptake by brain tissue, measured by positron emission tomography (PET), is accepted by regulatory agencies like the Food and Drug Administration (FDA) and the European Medicine Agencies (EMA) for assessing amyloid load in people with dementia. Its added value is mainly demonstrated by excluding Alzheimer's pathology i...

Background: Portomesenteric vein thrombosis (PMVT) is a rare but severe complication after laparoscopic bariatric surgery, with potentially serious consequences. We aimed to describe the incidence, clinical features, management, outcome, and midterm follow-up in patients with PMVT after laparoscopic sleeve gastrectomy (LSG). Methods: This retros...

This is the protocol for a review and there is no abstract. The objectives are as follows: To evaluate the efficacy and safety of early (within 48 hours) versus delayed enteral nutrition (after 48 hours) in critically ill adults.

This is the protocol for a review and there is no abstract. The objectives are as follows: To determine the diagnostic test accuracy (DTA) of the 18F PET ligands for Aβ (18F-Florbetapir, 18F-Florbetaben, and 18F-Flutemetamol) as the index tests for detecting participants with mild cognitive impairment (MCI) at baseline who would clinically progress...

Background & aims: Nutritional support in the acutely ill is a complex topic. Clinical practice guidelines (CPGs) have been developed to assist healthcare professionals working in this field. However, the quality of these clinical guidelines has not yet been systematically assessed. The objective of our study was to identify and assess the quality...

Introduction: Acute bronchiolitis (AB) is a frequent respiratory disease in infants. Objectives: To compare epidemiological characteristics of two groups of patients hospitalized due to AB in two hospitals with different SE conditions and to evaluate clinical management and hospital evolution. Methods: We performed a prospective clinical questionna...

Con el objeto de discutir el rol de la infección por virus varicela zóster (VVZ) como desencadenante inhabitual de Púrpura de Schonlein-Henoch (PSH) se comunica el caso de una paciente de 4 años, con PSH y varicela. La evolución del PSH en esta niña se complica con dolor abdominal intenso, requiriendo terapia esteroidal sistémica. Al quinto día de...

In order to discuss the role of varicella zoster virus (VZV) infection as a potential trigger of Henloch-Schonlein Purpura (HSP) we present the case of a 4 year old boy with HSP and varicella. The clinical course was complicated by severe abdominal pain, requiring systemic steroids. On the 5th day of evolution, a vesicular exanthem appeared (VZV co...