Paul K. S Magut

Dedan Kimathi University of Technology · Department of Chemistry

This research paper focuses on the geochemical mapping of Sulfur to characterize the Olkaria geothermal field, a field associated with geothermal power generation in the northeast of Nairobi. The current geochemical methods used are CO₂ and N₂ however, a discrepancy associated with the biogenic sources of CO₂ render...

The increasing economic growth in Kenya has encouraged the growth of the leather sector. Kenya in its long-term vision to become an industrialized middle-income country by 2030, has identified the key role that the leather sector will play. There is a growing number of SMEs engaged in leather goods and footwear manufacturing around the country. A l...

Herein, we report on the role of endocytosis in the selective chemotherpeutic toxicity of Rhodamine 6G (R6G) based nanomaterials, i.e. nanoGUMBOS, that are derived from a Group of Uniform Materials Based on Organic Salts (GUMBOS). Evaluation of cellular uptake in the presence and absence of endocytosis inhibitors suggests nanoGUMBOS internalization...

In this study, we report on the synthesis and characterization of multifunctional ionic liquid crystals (melting points below 100 °C) which possess chirality, fluorescent behavior, as well as mesomorphic and magnetic properties. In this regard, (1R, 2S) (-)-N-Methylephedrine ((-)MeEph), containing a chiral center, is linked with variable alkyl chai...

Emerging concepts of theranostics have led to development of numerous multifunctional nanomaterials using various synthetic approaches. Herein, we report a simplistic approach towards design of an Iron(III) phthalocyanine based pH responsive-magnetic-fluorescent nanoparticles for combined multimodal diagnosis and possible site selective therapy. Tr...

RATIONALE: Detection of hydrophobic peptides remains a major obstacle for matrix-assisted laser desorption/ionization mass spectrometry (MALDI-MS). This stems from the fact that most matrices for MALDI are hydrophilic and therefore have low affinities for hydrophobic peptides. Herein, 1-aminopyrene (AP) and AP-derived group of uniform materials bas...

A rapid liquid phase extraction employing a novel hydrophobic surfactant-based room temperature ionic liquid (RTIL), tetrabutylphosphonium dioctyl sulfosuccinate ([4C4P][AOT]), coupled with capillary electrophoretic-UV (CE-UV) detection is developed for removal and determination of phenolic compounds. The long-carbon-chain RTIL used is sparingly so...

Over the last decade in materials science, molecular electronics has emerged as one of the most rapidly developing interdisciplinary research areas with the prospects of ultimate miniaturization and integration of functional organic species with traditional silicon based semiconductor technology. To this end, fundamental studies to investigate the...

Molecular electronics, where nanoscale organic species are utilized as active electronic components, offers a promising approach towards ultimate miniaturization and integration of hybrid electronic materials (HEMs) with traditional silicon based complementary metal oxide semiconductors (CMOS) technology. Toward this end, fundamental research studi...

Chemotherapeutic agents with low toxicity to normal tissues are a major goal in cancer research. In this regard, the therapeutic activities of cationic dyes, such as rhodamine 6G, toward cancer cells have been studied for decades with observed toxicities toward normal and cancer cells. Herein, we report rhodamine 6G-based organic salts with varying...

A novel pH sensitive, colorimetric ionic liquid nanosensor based on phosphonium salts of fluorescein is reported. Herein, fluorescein salts of various stoichiometries were synthesized by use of a trihexyltetradecylphosphonium cation [TTP]+ in combination with dianionic [FL]2− and monoanionic [FL]− fluorescein. Nanomaterials derived from these two c...

We report on the synthesis and characterization of a PEGylated IR786 GUMBOS (Group of Uniform Materials Based on Organic Salts). The synthesis of this material was accomplished using a three step protocol: (1) substitution of chloride on the cyclohexenyl ring in the heptamethine chain of IR786 by 6-aminohexanoic acid, (2) grafting of methoxy polyet...