Paul Hutchins

Paul Hutchins
Children's Hospital at Westmead · Children's Hospital at Westmead Clinical School

MA BM BCh ( Oxon) FRACP MRCPCH MRCP DCH

About

23
Publications
8,670
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934
Citations

Publications

Publications (23)
Article
To investigate whether recent Australian practice conforms to the draft 2009 National Health and Medical Research Council (NHMRC) guidelines on the management of attention deficit hyperactivity disorder. Data from the 2007 Special Review on Attention Deficit Hyperactivity Disorder in Children and Adolescents in New South Wales (NSW) were examined....
Article
The authors evaluated 51 consecutive children with NF1 (aged eight to 16 years) to determine the frequency of intelectual impairment and learning disability due to NF1 alone, the profile of learning disabilities and the effect of clinical variables. 40 children completed the full assessment protocol. There was no support for a profile of predominan...
Article
Full-text available
This study estimates the sensitivity and specificity of the social communication questionnaire (SCQ) for autistic spectrum disorders in preschool children at high risk for developmental problems referred to a tertiary centre and compares the predictions of the SCQ and the referrer. The SCQ was completed by 81 parents prior to multidisciplinary asse...
Article
To highlight the increase in the number of cases of clonidine overdose admitted to a specialist paediatric hospital, with particular reference to the clinical features, clinical course and circumstances surrounding the incident. Cases of clonidine overdose were identified by review of the emergency department attendance register, the intensive care...
Article
In order to monitor whether paediatric education has adapted to meet modern practice 91 paediatric advanced trainees were surveyed to elicit their satisfaction with developmental-behavioural (DB) training. A response of 69% was obtained to a postal questionnaire. The traditional imbalance persists, with trainees considering themselves significantly...
Article
The authors evaluated 51 consecutive children with NF1 (aged eight to 16 years) to determine the frequency of intelectual impairment and learning disability due to NF1 alone, the profile of learning disabilities and the effect of clinical variables. 40 children completed the full assessment protocol. There was no support for a profile of predominan...
Article
To determine whether previously reported areas of increased T2 signal intensity on MRI examination in children with neurofibromatosis type 1 (NF 1) are associated with deficits in development and learning common in this population, we evaluated 51 children with NF 1 (aged 8 to 16 years). Forty children completed the full assessment protocol (MRI, m...
Article
Full-text available
The issue of the ventilator-dependent child is a relatively-new one in Australia. Ventilator-dependent children pose complex and unique ethical, medical, economic and psychological problems. The experience of two Australian centres that are involved with the care of ventilator-dependent children is reported. Most of these children now are being car...
Article
Peripheral blood mononuclear cells (PBMC) from thirteen asthmatic children, and from normal control subjects, were pre-incubated with and without concanavalin A (con A), washed, and cultured with fresh allogenic PBMC from healthy donors. The con A pre-treated cells from fifteen of seventeen normal controls clearly suppressed the blast transformatio...
Article
Full-text available
Six healthy children, born in the UK, travelled to their parental homeland and developed a severe form of traveller's diarrhoea. This was characterised by rapid loss of weight and chronic diarrhoea. On return to this country, investigation in 5 of them showed an abnormal, small intestinal mucosa. There was a high incidence of pathogens and potentia...
Article
A male infant, aged 1 year 3 months, was admitted to the hospital with protracted diarrhoea, vomiting, and weight loss. The diarrhoea and vomiting coincided with an outbreak of acute diarrhoea and vomiting affecting other family members. Biopsy showed a flat small intestinal mucosa which did not respond to a diet free of gluten, cow's milk, and egg...
Article
Not all abnormal reactions to foods, that is, food intolerance, involve immunological mechanisms which can be defined as food allergic disorders. Gastrointestinal FAD may present as non-specific symptoms such as abdominal discomfort or abnormal gut motility, which may have many different causes. Many gastrointestinal disorders, either in symptoms o...
Article
Full-text available
Four different carbohydrate electrolyte solutions were provided for children under 18 months with acute gastroenteritis treated as outpatients. Osmolality and sodium content were measured in samples of solutions as given by the parents. All types of feed were made up with marked inaccuracy. Osmolality was sometimes unacceptably high in solutions co...
Article
Full-text available
Simultaneous sampling was performed to determine whether saliva could replace plasma in the monitoring of theophylline dosages. Forty-eight children with moderate to severe asthma received oral theophylline preparation (usually sustained release) on a daily basis. They provided simultaneous saliva and plasma samples at routine out-patient visits. S...
Article
Full-text available
Seventy-three children under the age of 18 months presenting with acute gastroenteritis were given an electrolyte mixture with added sucrose or glucose in a randomized double-blind trial. The time taken to recovery in those successfully treated as out-patients was identical. However, of the 34 who received glucose, 11 (32%) required admission compa...
Article
It has been estimated that each individual has a one in 50 chance of producing a child with a serious congenital disorder; for most purposes a risk of one in 10 or greater is accepted as high. The accuracy of prediction will depend on the precise diagnosis, the mode of inheritance, and the family history, but for many conditions only empirical risk...

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