Patrick MusondaUniversity of Zambia | UNZA · School of Public Health
Patrick Musonda
About
42
Publications
11,402
Reads
How we measure 'reads'
A 'read' is counted each time someone views a publication summary (such as the title, abstract, and list of authors), clicks on a figure, or views or downloads the full-text. Learn more
400
Citations
Citations since 2017
Introduction
Skills and Expertise
Publications
Publications (42)
Accurate assessment of fetal gestational age (GA) is critical to the clinical management of pregnancy. Industrialized countries rely upon obstetric ultrasound (US) to make this estimate. In low- and middle- income countries, automatic measurement of fetal structures using a low-cost obstetric US may assist in establishing GA without the need for sk...
The increase in health research in sub-Saharan Africa (SSA) has led to a high demand for biostatisticians to develop study designs, contribute and apply statistical methods in data analyses. Initiatives exist to address the dearth in statistical capacity and lack of local biostatisticians in SSA health projects. The Sub-Saharan African Consortium f...
The increase in health research in sub-Saharan Africa (SSA) has generated large amounts of data and led to a high demand for biostatisticians to analyse these data locally and quickly. Donor-funded initiatives exist to address the dearth in statistical capacity, but few initiatives have been led by African institutions. The Sub-Saharan African Cons...
Accurate estimates of gestational age at birth are important for preterm birth surveillance but can be challenging to reliably acquire in low and middle income countries. Our objective was to develop machine learning models to accurately estimate gestational age shortly after birth using clinical and metabolic data. We derived and internally valida...
Background: HIV individuals receiving Antiretroviral Therapy (ART) are at increased risk of metabolic related conditions/diseases. However, in sub-Saharan African countries, including Zambia, screening for metabolic syndrome (MS) is typically not embedded in the management of HIV. Amidst this is the burden of virological failure (VF) among ART pati...
Background Neisseria gonorrhea, the causative agent of Gonorrhea, has developed antibiotic resistance to the “last-line” Cephalosporin’s, Quinolones and Macrolides which is cause for concern. In Zambia, despite recommendations of discontinued use, Ciprofloxacin is used for treatment. The lack of an active surveillance system, appropriate and struct...
Background
Malaria is a major public health problem in Zambia with an estimated 4 million confirmed cases and 2389 deaths reported in 2015. Efforts to reduce the incidence of malaria are often undermined by a number of factors such as human mobility which may lead to introduction of imported infections. The aim of this study was to establish the bu...
Background:
The large global burden of rheumatic heart disease (RHD) has come to light in recent years following robust epidemiologic studies. As an operational research component of a broad program aimed at primary and secondary prevention of RHD, we sought to determine the current prevalence of RHD in the country's capital, Lusaka, using a moder...
Abstract Background Access factors associated with maternal death are important to understand because they are considered to be an essential measure of women’s health and indicative of the performance of health care systems in any community globally. This study aimed to analyse the access risk factors linked to maternal deaths in Lundazi district o...
Several studies have attributed the etiopathogenesis of chronic Schistosoma mansoni related hepatic fibrosis to unregulated immune responses against trapped parasite ova in the host. However, there is limited data on immune profiles associated with varying degrees of the disease in a population under chronic exposure to the parasite. We therefore i...
This paper identifies some major drivers of per capita public health expenditure growth in Tanzania using nationally representative annual data between 1995 and 2014. It used Bayesian model based on Markov Chain Monte Carlo (MCMC) simulation. The empirical result shows that both the real GDP per capita and population age 65 years and older exert a...
Background
Early marriages, pregnancies and births are the major cause of school drop-out among adolescent girls in sub-Saharan Africa. Birth complications are also one of the leading causes of death among adolescent girls. This paper outlines a protocol for a cost-benefit analysis (CBA) and an extended cost-effectiveness analysis (ECEA) of a compr...
Background
Hepatitis B is a viral infection of the liver and causes both acute and chronic disease. It is transmitted through contact with an infected person’s bodily fluids. It is an occupational hazard for healthcare workers and can be prevented by the administration of a vaccine. It is recommended that healthcare workers be vaccinated against va...
Background
Prompt and appropriate treatment of streptococcal pharyngitis decreases the risk of acute rheumatic fever and rheumatic heart disease (RHD). Understanding public perceptions and behaviors related to sore throat is fundamental to inform health programs aimed at eliminating new cases of RHD in endemic regions. We sought to describe the epi...
Background
Tuberculosis and severe acute malnutrition (SAM) in children pose a major treatment and care challenge in high HIV burden countries in Africa. We investigated the prevalence of Tuberculosis notifications among hospitalised under-five children with severe acute malnutrition. A retrospective review of medical records for all children aged...
Background:
In resource-limited setting, there is scarce evidence comparing antiretroviral therapy (ART) outcomes among HIV-infected adolescents to that of other age groups.
Methods and study design:
We analysed data from 25 ART facilities in Lusaka District, comparing treatment-naïve ART-eligible young adolescents (10-14 years), older adolescen...
This paper establishes empirical evidence related with correlation and causality between economic growth (as measured by GDP per capita) and under-five malaria mortality in Tanzania Mainland. The goal is to contribute knowledge on the existing relationship between economic growth and under-five malaria mortality. Correlation and scatter regression...
Background
The Better Health Outcomes through Mentoring and Assessment (BHOMA) project is a cluster randomized controlled trial aimed at reducing age-standardized mortality rates in three rural districts through involvement of Community Health Workers (CHWs), Traditional Birth Attendants (TBAs), and Neighborhood Health Committees (NHCs). CHWs condu...
Using data for World Bank Development Indicators (2015) database from 1995 to 2013, this paper explores the impact of public health expenditure on national health outcomes in Tanzania while GDP per capita and improved sanitation facilities as explanatory variables were controlled for. Two national health outcomes indicators namely, infant and under...
This paper establishes empirical evidence related with correlation and causality between economic growth (as measured by GDP per capita) and under-five malaria mortality in Tanzania Mainland. The goal is to contribute knowledge on the existing relationship between economic growth and under-five malaria mortality. Correlation and scatter regression...
Background:
Adolescent pregnancies pose a risk to the young mothers and their babies. In Zambia, 35% of young girls in rural areas have given birth by the age of 18 years. Pregnancy rates are particularly high among out-of-school girls. Poverty, low enrolment in secondary school, myths and community norms all contribute to early childbearing. This...
Introduction
In spite of the extreme importance of an early antenatal care visit, more than 50% of Zambian pregnant women book for antenatal care late. We aimed to determine factors associated with late antenatal care booking in Zambia.
Methods
Data stem from the 2007 Zambia Demographic and Health Survey where information on socio-demographic, soc...
Objective:
Traditionally, urodynamic studies (UDS) have been used to assess lower urinary tract symptoms (LUTS), but their routine use is now discouraged. While urodynamic stress incontinence is strongly associated with the symptom of stress urinary incontinence (SUI) and a positive cough test, there is a weak relationship between symptoms of over...
Sub-Saharan Africa has a shortage of well-trained biomedical research methodologists, in particular, biostatisticians. In July 2014, a group of biostatisticians and researchers from the region attended a brainstorming workshop to identify ways in which to reduce the deficit in this critical skill. The workshop recognized that recommendations from p...
Background: Research outputs in sub-Saharan Africa may be limited by a scarcity of clinical research expertise. In Zambia, clinical and biomedical postgraduate students are often delayed in graduation due to challenges in completing their research dissertations. We sought to strengthen institutional research capacity by supporting student and facul...
We are very grateful to be given the opportunity to reply to the letters by Evans et al and King about this paper. Evans et al mention that there are several potential sources for error and misinterpretation when using cortisol readings unadjusted for either gender or assay type. However, in clinical practice cortisol measurements are often reporte...
Objective
To assess the prevalence and severity of voice symptoms in individuals with a diagnosis of autoimmune disease.Study DesignCross-sectional survey.SettingStudy participants were recruited from a rheumatology tertiary referral clinic at Norfolk and Norwich University Hospital.Subjects and MethodsA cross-sectional questionnaire analyzing 109...
Current demographic trends suggest that there will be increasing numbers of older people in the future. Relatively little information is available regarding factors which influence mortality in the acutely unwell oldest old. This study uses the CART technique on data relating to the oldest old, to identify potential predictors of inpatient mortalit...
This chapter summarizes some statistical issues in vaccine safety. It provides a detailed description of a popular method that is used in modelling adverse outcomes in vaccines, known as the self-controlled case series method. The self-controlled case series method (SCCSM), or case series method is a modified cohort method for estimating the relati...
Objective:
Despite the widespread use of the short synacthen test (SST), there remains no clear consensus on sampling times for the measurement of serum cortisol that best determines adrenal reserve. We set out to establish whether there is any value in measuring serum cortisol at 60 min following administration of synacthen.
Design:
Retrospecti...
To establish uptake of influenza vaccine amongst care home clinical staff in Greater Nottingham, and to investigate what could be done to improve vaccine uptake in this group.
Postal questionnaire surveys were used. In the first instance, a total sample survey was used. In the second instance, a sample of care home staff was surveyed, randomized at...
Quality of life (QOL) in the context of education is an understudied topic and research related to its’ relation to the sense
of coherence (SOC), level of optimism (LOO) and self-efficacy (SE) among students seems to be missing. The rationale for this
survey was to fill this gap in knowledge and therefore, the aim of the study is to examine the rel...
Projects
Projects (3)
SSACAB brings together African and Northern academic/research institutions to develop and improve biostatistical skills among researchers. The ultimate goal is to create research nodes of excellence to grow the discipline and a biostatistical network to nurture researchers with advanced skills and expertise. The consortium is developing, strengthening and implementing high quality biostatistics masters’ level training at the lead and partner institutions. It provides PhD training aimed at developing expertise, skills, and promoting the production of research leaders in biostatistics in Africa. SSACAB supports the development of a network of statisticians to deliver statistical courses for biomedical researchers, develop and implement statistical theory to analyse health data, and create the framework for improved biostatistical skills among health researchers and academics in nine African countries. SSACAB integrates with the existing Sub-Saharan Africa Network (SUSAN) under the International Biometrics Society (IBS).
