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Introduction
Patricia Enel currently works at the Faculté de Médecine, Aix-Marseille Université. Patricia does research in Public Health, Epidemiology and Infectious Diseases. Their most recent publication is 'Factors associated with social deprivation among older persons living with HIV'.
Publications
Publications (65)
Previous studies showed that Erotic industry sShows (ES) were appropriate events for sexual health promotion and testing interventions. A cross-sectional survey exploring screening practices, sexual behaviors, substance use, and sexual motives for substance use was conducted in ES in December 2017 and completed by 781 respondents. Overall, . Eighte...
Purpose of review:
This multicentre, cross-sectional study was carried out in the South of France to assess the association between frailty phenotype and antiretroviral therapy (ART) in older persons living with HIV (PLWHIV). Sociodemographic and HIV data, geriatric assessment, comorbidities, behavioral and age-related variables and the five frail...
Objectives
We assessed virological outcomes of rilpivirine use in France from 2012 to 2017, in three groups of people living with HIV (PLHIV): (i) antiretroviral (ARV)-naive PLHIV; (ii) ARV-experienced PLHIV switching to rilpivirine while failing therapy; and (iii) ARV-experienced PLHIV switching to rilpivirine while virologically controlled.
Meth...
Introduction
Les infections bactériennes sévères sont la première cause de morbidité chez les personnes vivant avec le VIH (PVVIH). Nous avons cherché à évaluer leur incidence et à analyser leurs déterminants.
Matériels et méthodes
La population d’étude était celle des PVVIH âgées d’au moins 15 ans suivies dans une cohorte prospective nationale mu...
The life-span of people aging with HIV (PHIV) tends to reach people without infection, reflecting the effectiveness and tolerance of antiretroviral treatment and improvement of multidisciplinary management. Comorbidities or HIV-inflammaging seems to be the main determinants of frailty phenotype in PHIV. Prevalence of frailty in PHIV is frequent (5%...
Aging persons living with HIV may develop multiple health problems, including comorbidities, and altered physical and mental health, earlier than non-infected people. They may also experience social deprivation. We assessed the prevalence of social deprivation and its relationship with health indicators in older persons living with HIV. An 18-month...
The current aim of the fight against the HIV epidemic is to reduce the proportion of missed opportunities for HIV diagnosis. Erotic industry Shows (ES) were deemed to be appropriate events to organize awareness campaigns and to propose HIV Rapid Diagnostic Test (HIV-RDT) to people who are sexually active and likely to engage in unsafe sex practices...
The 20th International Symposium on HIV and Emerging Infectious Diseases took place in Marseille, France. It had a refreshing European look with reinforced partnerships with the European AIDS Clinical Society and the British HIV Association and with international speakers and participants. Topics included HIV and global health, HIV and hepatitis cu...
The 20th International Symposium on HIV and Emerging Infectious Diseases took place in Marseille, France. It had a refreshing European look with reinforced partnerships with the European AIDS Clinical Society and the British HIV Association and with international speakers and participants. Topics included HIV and global health, HIV and hepatitis cu...
As HIV-infected patients grow older, some accumulate multiple health problems earlier than the noninfected ones in particular frailty phenotypes. Patients with frailty phenotype are at higher risk of adverse outcomes (worsening mobility, disability, hospitalization, and death within three years).
Our study aimed to evaluate prevalence of frailty in...
Update on the management of HIV in France. The fight against the epidemic and the management of human immunodefi ciency virus infection are constantly evolving and increasingly eff ective. The concept of combined and personalised prevention takes into account the latest available tools, in addition to condoms. New screening strategies are also in p...
En France, on estime qu’environ 30 000 personnes seraient infectées par le VIH sans être diagnostiquées. Les salons régionaux de l’érotisme français sont apparus comme des lieux privilégiés pour la mise en œuvre de campagnes de sensibilisation à la prévention du VIH et des infections sexuellement transmissibles et de proposition de test de dépistag...
Objectives. Although the last international guidelines for aPL recommended determination of IgA aCL and anti-b 2 glycoprotein I (ab2GPI) antibodies for the evaluation of APS in the absence of conventional IgG or IgM aCL and ab2GPI antibodies, the clinical value of these antibodies remains controversial. We evaluated the clinical utility of IgA aPL...
Abstract To evaluate the incidence and risk factors of first-highly active antiretroviral therapy (HAART) modifications/interruptions and their causes in a cohort of newly-treated patients by using a competing risk model. In nine centers of the French cohort Dat'AIDS, in 1 year and 2 years of censorship, a competing risk analysis was implemented in...
The French Hospital Database on HIV (FHDH) is a hospital-based multicentre open cohort with inclusions ongoing since 1989. The research objectives focus mainly on mid-and long-term clinical outcomes and therapeutic strategies, as well as severe AIDS and non-AIDS morbidities, and public health issues relative to HIV infection. FHDH also serves to de...
Background
At the request of the Hospitalization Regional Agency (ARH) – in the context of the 2007–2011 plan aimed at improving the quality of life for patients affected by chronic diseases – the purpose of this work was to draw up a clear assessment of the 2008 Therapeutic Education programmes in the Provence-Alpes-Côte d’Azur (PACA) region. The...
BACKGROUND
At the request of the Hospitalization Regional Agency (ARH)--in the context of the 2007-2011 plan aimed at improving the quality of life for patients affected by chronic diseases--the purpose of this work was to draw up a clear assessment of the 2008 Therapeutic Education programmes in the Provence-Alpes-Côte d'Azur (PACA) region. The st...
Most clinical guidelines recommend that AIDS-free, HIV-infected persons with CD4 cell counts below 0.350 × 10(9) cells/L initiate combined antiretroviral therapy (cART), but the optimal CD4 cell count at which cART should be initiated remains a matter of debate.
To identify the optimal CD4 cell count at which cART should be initiated.
Prospective o...
Post-exposure prophylaxis (PEP) is recommended for the management of sexual HIV-risk exposure. However, a high percentage of exposed patients discontinue both their 28-day prophylaxis course before 15 days and HIV testing follow-up before M3. The objective of this study is to assess the efficacy of a counseling intervention in enhancing both adhere...
Objective. Post-exposure prophylaxis (PEP) is recommended for the management of sexual HIV-risk exposure.
However, a high percentage of exposed patients discontinue both their 28-day prophylaxis course before 15 days
and HIV testing follow-up before M3. The objective of this study is to assess the efficacy of a counseling
intervention in enhancing...
The aim of this article is to describe the development of a dynamic French cohort of HIV-infected patients, the methodological issues and decisions made, and the characteristics of the patients currently enrolled.
Data are collected during medical encounters. Data quality is ensured by automated checks during data capture, by regular controls, by a...
Objectif Decrire les caracteristiques des patients ayant ≥ 20 ans de seropositivite (Pat20) pris en charge en 2007, via la cohorte NADIS. Methode Etude transversale de la cohorte NADIS regroupant les donnees, anonymisees et soumises a un controle de qualite standardise, de services hospitalo-universitaires specialises dans l’infection a VIH utilisa...
We analysed mortality, morbidity and trends in the characteristics, including risk factors of late testing, in 6805 the patients
newly diagnosed for HIV infection between 1 January 1996 and 1 July 2006. The proportion of individuals in high risk groups
of infection, as MSM, has decreased over time whereas the proportion of those in low risk of infe...
We used a two-source capture-recapture method to estimate the number of patients diagnosed at the time of primary HIV infection in France between 1999 and 2002. The sources were the French PRIMO cohort and the French Hospital Database on HIV. The estimated number of patients was 325 per year, which represents only 5% (approximately 6000 cases) of a...
Objective
This study had for aim to evaluate the immuno-virological and therapeutic profile of a cohort of 7416 HIV-1 infected patients followed in six French hospital with the Nadis© software.Method
This cross sectional and retrospective study was performed between June 1, 2004 and June 1, 2005. We analyzed the demographic (sex, age, HIV infection...
This study had for aim to evaluate the immuno-virological and therapeutic profile of a cohort of 7416 HIV-1 infected patients followed in six French hospital with the Nadis software.
This cross sectional and retrospective study was performed between June 1, 2004 and June 1, 2005. We analyzed the demographic (sex, age, HIV infection route), immunovi...
Background. We obtained estimates of the incidence of tuberculosis (TB) among patients receiving HAART and identified determinants of the incidence. Methods. We analyzed the incidence of TB during the first 3 years after initiation of HAART among 17,142 treatment-naive, AIDS- free persons starting HAART who were enrolled in 12 cohorts from Europe a...
To identify factors related to delayed testing, and delayed or interrupted care-seeking or treatment uptake, among HIV-infected patients.
HIV-infected patients hospitalized for an opportunistic infection (OI) cases were included in a prospective study and compared with controls matched by age and sex who had regular follow-up and treatment. Patient...
Objective. – The Nadis electronic medical patient record allows real time constitution of a database including the clinical, therapeutic, biological, and epidemiological features of HIV-positive patients.Methods. – Data concerning HIV-infected patients followed-up in 6 French University Hospitals was collected. Data quality was assessed on a regula...
Objective
To study the prognosis of HIV-infected patients with virological failure after exposure to three classes of antiretroviral drugs (ARVs).
Design
Cohort study. Setting: French Hospital Database on HIV.
Patients
Patients previously exposed to at least two nucleoside reverse transcriptase inhibitors (NRTIs), two protease inhibitors and one...
OBJECTIVE:
The Nadis electronic medical patient record allows real time constitution of a database including the clinical, therapeutic, biological, and epidemiological features of HIV-positive patients.
METHODS:
Data concerning HIV-infected patients followed-up in 6 French University Hospitals was collected. Data quality was assessed on a regular...
To study immunologic and clinical responses to HAART in patients over 50 years old.
A prospective cohort study which included 68 hospitals in France. A total of 3015 antiretroviral-naive patients, 401 of whom were aged 50 years or over, were enrolled following initiation of HAART. The influence of age on the mean CD4 cell count increase on HAART wa...
to develop an electronic medical record for patients living with HIV, HBV or HCV in order to improve their management, facilitate communication between all the caregivers, and to create a useful medical database for research and assessments. This project (NADIS 2000) involved 6 centres of Infectious Diseases in France in partnership with Fédialis M...
La publication d'un article dans le BEH n'empêche pas sa publication ailleurs. Les articles sont publiés sous la seule responsabilité de leur(s) auteur(s) et peuvent être reproduits sans copyright avec indication de la source. face aux risques sanitaires ainsi que les circonstances du premier dépistage positif du VIH et les antécédents de dépistage...
A preliminary study realised in the second half of 1994, in the Infectious Unit of F. Houphouet Boigny Hospital (CHU Nord) pointed out some deficiencies in the data acquisition of drugs prescription for the DMI2 report (Dossier Medico-economique de l'Immunodeficience humaine: economic and epidemiologic data concerning hospital activities related to...
The prognosis of melanoma is closely related to tumor thickness at the time of surgical excision. Thickness depends on the duration of disease before diagnosis. This underlines the importance of information campaigns to promote early diagnosis of melanoma. The purpose of this study was to estimate the cost and effectiveness of a media campaign for...
At present, we can observe an evolution in ideas about the detection of HIV seropositivity through a qualitative analysis of specialised literature on the ethical aspects of AIDS. In the case of this disease, systematic screening of the population does not correspond to epidemiological criteria: it is wasteful, troublesome and costly. Whether it is...
At present questions are being asked world-wide about the risk of the AIDS epidemic. The discovery of an anti-HIV vaccine has become an urgent priority, but it also raises a number of sensitive questions. Ethical problems in this field are particularly delicate, since the perspectives of individual health and public health do not seem to coincide....
This bibliographical study involved first the exploitation of four data-banks: Medline, CNRS, Bioethics and AIDS, with the following key words (in conjunction with AIDS): ethics, human rights, confidentiality, legislation, jurisprudence. A total of 412 references were listed between 1983 and the end of 1987. Examination of the quantitative increase...
