Patricia Brock

Patricia Brock
University of Texas MD Anderson Cancer Center | MD Anderson · Department of Emergency Medicine

About

31
Publications
878
Reads
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259
Citations
Citations since 2017
14 Research Items
144 Citations
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Introduction

Publications

Publications (31)
Article
Full-text available
Immune checkpoint inhibitor monoclonal antibodies allow the host's immune system to attack tumors, which has revolutionized cancer care over the last decade. As the use of immune checkpoint inhibitors has expanded, so have autoimmune-like complications known as immune-related adverse events. These include the infrequent but increasingly more common...
Article
Background Delirium, poor performance status, and dyspnea predict short survival in the palliative care setting. Objective Our goal was to determine whether these three conditions, which we refer to as a “triple threat,” also predict mortality among patients with advanced cancers in the emergency department (ED). Methods The study sample included...
Article
Full-text available
Background Bamlanivimab is a monoclonal antibody that was granted an emergency use authorization by the US Food and Drug Administration in November 2020 for patients with mild to moderate coronavirus disease 2019 (COVID-19). It initially showed promising results with decreasing hospitalizations and return emergency department visits in immunocompet...
Article
Full-text available
Background Emergency medicine (EM) resident training in oncologic emergencies is limited, and significant gaps have been identified. Although 90% of emergency medicine residency program directors recognize the importance of residency training in oncologic emergencies, there is no standardized oncologic emergency curriculum. Objective We propose a f...
Chapter
Despite advancements in the creation and care of stomas in the course of cancer treatment, stoma complications are common, and patients frequently seek evaluation in the ED. These issues can arise soon after the operative procedure or may develop at a much later date. Problems may range from benign skin irritation to a life-threatening obstruction...
Article
Full-text available
Background: Cancer patients are vulnerable to the coronavirus disease (COVID-19) given their compromised immune system. The purpose of this study was to describe the presenting symptoms, inpatient stay trajectory, and survival outcomes, for cancer patients infected with COVID-19; who presented to the emergency department (ED) of a single center du...
Article
Full-text available
Rapid advances in cancer immunotherapy using immune checkpoint inhibitors have led to significantly improved survival. Rapid identification of the toxicity syndromes associated with these therapeutic agents is very important for emergency physicians because the population of patients diagnosed with cancer is increasing and cancer therapies includin...
Article
Treatment of human immunodeficiency virus(HIV) in cancer patients improves outcomes and reduces transmission of this oncogenic virus. HIV testing rates of cancer patients are similar to the general population (15-40%), despite the association with cancer. Our aim was to increase HIV screening in the Emergency Department(ED) of a comprehensive cance...
Article
138 Background: Early identification of cancer patients with short survival will help address end of life issues and avoid costly interventions. Dyspnea, delirium, and poor performance are known to predict short survival in palliative care. Our goal is to test whether these 3 conditions could predict mortality in the emergency department (ED) setti...
Article
Background To improve the management of advanced cancer patients with delirium in an emergency department (ED) setting, we compared outcomes between patients with delirium positively diagnosed by both the Confusion Assessment Method (CAM) and Memorial Delirium Assessment Scale (MDAS), or group A (n = 22); by the MDAS only, or group B (n = 22); and...
Article
Background: The frequency of delirium among patients with cancer presenting to the emergency department (ED) is unknown. The purpose of this study was to determine delirium frequency and recognition by ED physicians among patients with advanced cancer presenting to the ED of The University of Texas MD Anderson Cancer Center. Methods: The study p...
Article
Full-text available
Background: Lung cancer is the most common cause of cancer mortality in the United States. Venous thromboembolism (VTE) is the second-leading cause of death in patients with cancer; it was hypothesized that outcomes may be improved by preventing VTE. Primary thromboprophylaxis (PTP) in ambulatory patients with solid tumors remain uncertain. We cond...
Article
Although visiting the emergency departments (EDs) is considered poor quality of cancer care, there are indications these visits are increasing. Similarly, there is growing interest in providing palliative care (PC) to cancer patients in EDs. However, this integration is not without major challenges. In this article, we review the literature on why...
Conference Paper
Full-text available
Background: Lung cancer is the most common cause of cancer mortality in USA. Venous thromboembolism (VTE) is the second leading cause of death in cancer patients and it was hypothesized that the outcome might be improved by preventing the thrombotic events. The PTP in ambulatory solid cancer patients remains uncertain. We conducted a systematic rev...
Article
225 Background: HIV is a cancer-associated virus classically associated with KS, NHL, and cervical cancer, but more recently with anal cancer, lung, and head and neck cancers. HIV testing and treatment are important for cancer patients for three reasons: 1) HIV treatment is associated with reduced transmission of a cancer-associated virus. 2) HIV t...
Chapter
Neurologic complications of cancer and its therapy are varied and common, occurring in 30–50 % of cancer patients presenting to emergency departments or for neurologic consultations at teaching hospitals. However, a few true neurologic emergencies require rapid diagnosis and treatment to preserve neurologic function and, in some circumstances, save...
Article
Methods: The exact frequency of delirium among patients with advanced cancer presenting to emergency departments (EDs) is unknown. The purpose of this study is to determine the prevalence of delirium among patients with advanced cancer who present to the ED at MD Anderson Cancer Center. Results: A total of 624 patients were screen for this study...
Article
We implement an opt-out routine screening program in a high-volume, urban emergency department (ED), using conventional (nonrapid) technology as an alternative to rapid HIV tests. We performed a retrospective cohort study. Since October 2008, all patients who visited Ben Taub General Hospital ED and had blood drawn were considered eligible for rout...

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