Parichehr Hanachi

Parichehr Hanachi
Alzahra University · Department of biotechnology

Associate Professor

About

282
Publications
47,361
Reads
How we measure 'reads'
A 'read' is counted each time someone views a publication summary (such as the title, abstract, and list of authors), clicks on a figure, or views or downloads the full-text. Learn more
2,621
Citations
Introduction
Parichehr Hanachi currently works at the Department of Biotechnology , Faculty of Biological science, Alzahra University. Parichehr does research in Biotechnology, International Security and Arms Control and International Relations.  My Post Doctoral research work was involved on “Effect of Strobilanthes crispus on intracellular elements and enzyme in Liver of Rat” .I am also involved in phytomedicine in liver and breast cancer research. We are the first to report the use of Strobilanthus crispus extract and Azadirachta indica leaves and Barberis Vulgaris fruit extract has a potential anticancer agent. Numerous national and international seminars have been attended where papers were presented. Several short courses have been attended to increase the research capabilities.

Publications

Publications (282)
Article
Full-text available
Neurodegenerative disorders are characterized by mitochondrial dysfunction and subsequently oxidative stress, inflammation, and apoptosis that contribute to neuronal cytotoxicity and degeneration. Huntington’s (HD), Alzheimer’s (AD), and Parkinson’s (PD) diseases are three of the major neurodegenerative diseases. To date, researchers have found var...
Article
Full-text available
Scutellaria multicaulis is a medicinal plant indigenous to Iran, Afghanistan, and Pakistan. It has been widely used as a prominent herb in traditional medicine for thousands of years. This plant is reported to contain baicalein, wogonin, and chrysin flavonoids, which are a significant group of chemical ingredients which can cure different diseases,...
Preprint
Full-text available
Scutellaria multicaulis, a member of the Lamiaceae, is a medicinal plant indigenous to Iran, Afghanistan, and Pakistan. It has been widely used as a prominent herb in traditional medicine for thousands of years. This plant is reported with baicalein, wogonin, and chrysin flavonoids as a significant group of chemical ingredients, which can cure diff...
Preprint
Full-text available
The high levels of environmental pollutants like heavy metals and microplastics have prompted researchers to invent new remediation strategies, which might be accompanied by drawbacks, including the risk of secondary pollution, being costly, and inefficient. So, the aim of this study is the reduction of these environmental pollutants by the applica...
Article
Full-text available
Green synthesized nanoparticles (GSNPs) display fascinating properties compared to physical and chemical synthesized ones. GSNPs are currently used in numerous applications such as food packaging, surface coating agents, environmental remediation, antimicrobial, and medicine. In the present study, the aqueous leaf extract of Perilla frutescens L. h...
Preprint
Full-text available
Green synthesized‎ nanoparticles (GSNPs) display fascinating properties compared to physical and chemical synthesized ones. GSNPs‎ are currently used in numerous applications such as food packaging, surface ‎coating agents, environmental remediation, antimicrobial, and medicine. In the present ‎study, the aqueous leaf extract of Perilla frutescens...
Article
Scutellaria multicaulis is a medicinal herb which has been extensively prescribed in Iranian traditional medicine for treatment of infections, constipation, wounds, and also as medication for anxiety. To evaluate biological activities of biosynthesized silver nanoparticles, silver nanoparticles (Sm-AgNPs) were synthesized using S. multicaulis extra...
Conference Paper
Full-text available
Biosynthesis of nanoparticles using various plant materials is classified as a green technology because this production method does not employ toxic chemicals. The main purpose of this research was to identify the potential for Scutellaria sp. stems to synthesize silver nanoparticles (AgNO3-NPs) by a simple green method and to evaluate its efficacy...
Article
Full-text available
Heracleum persicum, commonly called Persian hogweed, is widely used as a spice in Iran. H. persicum comprises many natural compounds which are used in the treatment of multiple disorders. H. persicum stem extract was used for green synthesis of silver nanostructures (Hp-AgNPs) and their phytochemical contents and antioxidant, and anti-proliferative...
Article
Polystyrene nanoplastics (PS-NPs) can cause toxicity in aquatic organisms, but presence of natural organic matter (NOM) may alter toxicity of PS-NPs. To better understand effects of NOM on acute toxicity of PS-NPs, humic acid (HA) as a model of NOM was added to green microalga Chlorella vulgaris medium in the presence of amino-functionalized polyst...
Article
Full-text available
Microplastic (MP) is a major contaminant in the aquatic environment. In addition to the physical threats posed by microplastic ingestion, their potential as a vector for the transport of hydrophobic pollutants is required to be adequately addressed. This study examined the effects of polystyrene microplastics individually or combined with chlorpyri...
Article
Full-text available
Background Vitamin D (Vit D) deficiency/insufficiency is an important risk factor for several chronic conditions. We aimed to evaluate the knowledge and behavior of female adolescents with respect to the association between sunlight exposure, sunscreen use, and Vit D status. Methods This cross-sectional survey was performed in northeastern Iran, a...
Article
Microalgae are a very diverse group of aquatic plants that have numerous applications in biotechnology today. These microscopic photosynthesizers, have an extensive role in producing oxygen on Earth, they are found in almost all water sources on Earth due to their high dispersion and abundance. In this study, to investigate the effect of carbon sou...
Article
Increasing the abundance and wide distribution of microplastics is one of the most important concerns of biological communities. These particles can act as carriers of environmental chemical pollutants and pesticides. Absorption of these particles by living organisms, especially aquatic organisms, may cause changes in the gene expression as well as...
Article
Full-text available
In this study, the extracts of Dianthus and fumaria plants were studied. The total amount of flavonoids and phenolic compounds and antioxidant activities of methanolic, aqueos and ethanolic of the two extracts were studied with TLC and HPLC methods. Phenol and total flavonoids were measured and the antioxidant activities of the extracts analysed us...
Article
Abstract Introduction: Emergence of resistance to antimicrobial medications has led to the use of medicinal herbs for the treatment of infections. In this regard, this study aimed to investigate the antimicrobial effects of three extracts (i.e., ethanol/methanol, water, and acetone) of Melissa officinalis and Impatiens walleriana on four species o...
Article
Full-text available
The production of secondary metabolites varies under the different environmental conditions. The aim of this study was to investigate the effects of pH and temperature on the content of antioxidant compounds in a species of microscopic algae. First, the microalgal strain Monoraphidium sp. was cultured under the different temperature and pH treatmen...
Article
Full-text available
Presence of nanoplastics within aqueous media has raised concerns about their adverse impacts on aquatic organisms. This study evaluated toxic effects of amino-functionalized polystyrene nanoplastics (PS-NH2) with diameters of 90 (PS-NH2-90), 200 (PS-NH2-200) and 300 (PS-NH2-300) nm on green microalgae Chlorella vulgaris. A dose-dependent toxicity...
Article
Full-text available
Background There are increasing data highlighting the effectiveness of vitamin D supplementation in the treatment of vitamin D deficiency. But individuals vary in their responsiveness to vitamin D supplementation. In this study, the association between several cardiometabolic risk factors and the magnitude of response to vitamin D supplementation (...
Article
Full-text available
Background: Numerous studies investigate finding new drug candidates with an increasing death rate caused by cancer. Nowadays, herbal medicine has been noticed again because of the many side effects of chemical drugs. Objectives: In the current study, anthocyanin and carotenoid types of compounds of Ocimum basilicum and Impatiens walleriana were d...
Article
Full-text available
Microalgae are one of the rich sources of antioxidant compounds with health benefits. The synthesis of such compounds in microalgae cells can be increased under stress conditions. The aim of this study was to investigate the effect of heavy metals on antioxidant compounds production. For this purpose, both Monoraphidium and Scenedesmus strains were...
Article
Full-text available
Background: Secondary metabolites of plants such as phenol and flavonoids can neutralize free radicals. The antioxidant and cytotoxic activities of plants are related to phenolic or flavonoids compounds. The occurrence of drug resistance to antimicrobial drugs has led to the use of medicinal herbs in the treatment of infections. Antibiotic resistan...
Article
Full-text available
Background: Pistachio, with the scientific name Pistacia vera L., a native plant in Asia, is a member of the Anacardiaceae family. Pistachio nuts and skins are known as a rich source of phenolic compounds with antioxidant, anti-inflammatory, and antimicrobial properties. Objectives: In the current study, the industrial production of phenolic compou...
Article
Full-text available
Nowadays medicinal plants have been considered as the complementary medicine in cancer treatment by researchers. Some plants possess chemical compounds which are able to inhibit the growth of cancer cells or even eliminate them through apoptosis or necrosis. In current study anticancer effect of Tilia dasystyla and Polygonatum orientale Desf extrac...
Article
Ovarian cancer is one of the deadliest cancers in women causing abnormal cancerous cells that can spread and metastasize to other parts of the body. Secondary metabolites are highly variable in terms of structural and chemical properties and they are very important for plants survival. In this study, the extracts of two plants using three different...
Article
Microplastic (MP) sorption and transfer of chemical contaminants has been widely reported, yet few studies have investigated combined effects of contaminant-loaded MPs on organisms. This study examined effects of pristine or chlorpyrifos (CPF)-loaded polystyrene (PS)‎ fragments on histopathological and histomorphometrical biomarkers in rainbow trou...
Preprint
Full-text available
Background Accumulating data have highlighted the prominence of supplementation as an effective approach for vitamin D deficiency. But individuals vary in their response to vitamin D supplementation. In this study, the effect of cardiometabolic risk factors were evaluate on magnitude of response to vitamin D supplementation by using novel statistic...
Article
Full-text available
One of the main problems of rescue workers in confrontation of fired complex buildings is the lack of sufficient information about the building indoor environment and their emergency exit ways. Building information modeling (BIM) is a database for building a 3D model of building information to create a 3D building geometry network model. This paper...
Article
Background Vitamin D has recently attracted interest for its pleiotropic effects. Vitamin D supplements are a potentially important public health intervention, but the response to supplementation varies between individuals. Aim We aimed to assess the association between several neuropsychological parameters and the magnitude of response to vitamin...
Article
Free radicals cause many diseases in human. Antioxidants reduce the risk of cardiovascular disease and stroke by neutralizing free radicals and on the other hand, prevent progression of cancer. The natural antioxidant enhances antioxidant properties of plasma to prevent diseases such as heart disease, cancer, and stroke. Plants are a rich source...
Article
Full-text available
Although biosynthesized nanoparticles are regarded as green products, research on their toxicity to aquatic food chains is scarce. Herein, biosynthesized silver nanoparticles (Alcea rosea-silver nanoparticles, AR-AgNPs) were produced by the reaction of Ag ions with leaf extract of herbal plant Alcea rosea. Then, the toxic effects of AR-Ag-NPs and t...
Article
Full-text available
Background: Osteosarcoma; is one of the most common malignant tumors. Nowadays, because of the many side effects of cancer drugs, the usage of herbal medicine which can inhibit or eliminate cancer cells by their antioxidant compounds is increased. Objectives: In the present study anticancer effect of Tilia dasystyla and Polygonatum orientale Desf d...
Article
Full-text available
Presence of microplastics (MPs) in a broad range of wild and cultured marine organisms is well-documented, but transfer mechanisms by which cultured organisms are contaminated with MPs is poorly understood. MP loads in three Malaysian commercial brands of fish meal were investigated. Chemical composition of extracted MP-like particles was confirmed...
Article
Full-text available
Microalgae are one of the rich sources of natural antioxidants in various applications in the food and pharmaceutical industries. In this study, the effect of temperature stress (23˚c, 28˚c, 33˚c) and pH (5, 7, 8, 9) on antioxidant activity, phenolic and flavonoids content and on the amount of colorants in the microalgae Scenedesmus sp. was studied...
Article
Full-text available
Plastic debris is widespread and ubiquitous in the marine environment and ingestion of plastic debris by marine organisms is well-documented. Viscera and gills of 110 individual marine fish from 11 commercial fish species collected from the marine fish market were examined for presence of plastic debris. Isolated particles were characterized by Ram...
Article
Full-text available
Microplastics (MPs) are environmental contaminants that are of increasing global concern. This study investigated presence of MPs in four varieties of marine derived commercial fish meal, followed by identification of their polymer composition using Fourier-Transform Infrared (FTIR) spectroscopy. Exposure experiments were conducted on cultured comm...
Conference Paper
با گسترش علوم و فناوریهای مرتبط با شهر هوشمند همچون مدل اطلاعات ساختمان و سیستم های اطلاعات مکانی که برای مدیریت اطلاعات شهری حیاتی هستند، معمولاً این دو علم و فناوری به صورت مجزا استفاده می‌شوند. تلفیق این دو فناوری مسیر جدیدی است که هنوز در اول راه است که برای مدیریت و حل مسائل شهری راهکارهایی برای ارائه دارد؛ از این¬رو شناخت و تحلیل این دو فناور...
Conference Paper
Full-text available
The ubiquitous presence and persistency of microplastics contamination in aquatic ecosystems are considered a growing problem. The ingestion of microplastics has been reported in a variety of aquatic animals. The aim of this study was to investigate bioaccumulation of polystyrene (PS) microplastics in gill and gastrointestinal tract of rainbow trou...
Article
Full-text available
Background: Free radicals cause many diseases in humans. Antioxidants reduce the risk of cardiovascular disease and stroke by neutralizing free radicals and on the other hand, prevent the progression of cancer. The natural antioxidant enhances the antioxidant properties of plasma to prevent diseases such as heart disease, cancer, and stroke. Second...
Article
Aim: This study was performed to evaluate the cytotoxic effect of Ocimum basilicum and Impatiens walleriana aqueous extract on the gastric cancer of AGS cell line. Material and methods: FRAP method was used to measure the antioxidant activity of Ocimum basilicum and Ipatiems walleriana extracts. After preparation of O. basilicum and I. walleriana...
Article
Full-text available
Background: Vitamin D deficiency is a global problem that may be improved by vitamin D supplementation; however, the individual's response to the intervention varies. We aimed to investigate possible genetic factors that may modify the impact of environmental exposure on vitamin D status. The candidate gene variant we investigated was the Gc gene-...
Article
Full-text available
The presence and accumulation of plastic and microplastic (MP) debris in the natural environment is of increasing concern and has become the focus of attention for many researchers. Plastic debris is a prolific, long-lived pollutant that is highly resistant to environmental degradation, readily adheres hydrophobic persistent organic pollutants and...
Article
Full-text available
The presence and accumulation of plastic and microplastic (MP) debris in the natural environment is of increasing concern and has become the focus of attention for many researchers. Plastic debris is a prolific, long-lived pollutant, that is highly resistant to environmental degradation, readily adheres hydrophobic persistent organic pollutants and...
Article
Full-text available
Aims: Imbalance between the production of free radicals and the antioxidant defense system leads to oxidative stress. In addition, plants can reduce stress-induced oxidative damage. In this study we evaluated the effects of aerobic exercise with cinnamon intake on serum oxidative capacity in active women. Materials & Methods: 28 female students of...
Conference Paper
Relation between mental health and environmental factors are of growing interest in psychology, health conservation .Visiting Green space has been associated with a wide range of health benefits, like stress reduction. Many studies have showed that people living in environments with more green space, has better physical and mental health than peopl...
Article
Full-text available
Cytokines play a key role in the pathogenesis of coronary artery disease (CAD). The aim of current study was to investigate the relationship between the serum concentrations of 12 cytokines with mortality and extent of CAD in individuals undergoing angiography and healthy controls. 342 CAD patients were recruited and divided into 2 groups: those wi...
Article
Full-text available
Background In tissue engineering, scaffold characteristics play an important role in the biological interactions between cells and the scaffold. Cell adhesion, proliferation, and activation depend on material properties used for the fabrication of scaffolds. Objective In the present investigation, we used collagen with proper characteristics inclu...
Article
Full-text available
The problem of overcrowding of mega cities has been bolded in recent years. To meet the need of housing this increased population, which is of great importance in mega cities, a huge number of buildings are constructed annually. With the ever-increasing trend of building constructions, we are faced with the growing trend of building infractions and...
Conference Paper
Background and objective: Cancer is the second reason of death in worldwide and increasing each day. Cancer may have different causes such as environmental factors and life style that lead to production of free radicals in human body. Prescription medicine is not to prefer today because of the high cost and their unwanted side effects, such as many...
Article
Background Vitamin D deficiency is a prevalent and important global health problem. Because of its role in growth and development, vitamin D status is likely to be particularly important in adolescent girls. Here, we explored the effects of high-dose vitamin D supplementation on cardio-metabolic risk factors. Methods We have examined the effects o...
Article
Background and aims: Coronary heart disease (CHD) is an important public health problem globally. Algorithms incorporating the assessment of clinical biomarkers together with several established traditional risk factors can help clinicians to predict CHD and support clinical decision making with respect to interventions. Decision tree (DT) is a da...
Conference Paper
The rapidly increasing population and expanding industries causes contamination of water resources to different chemical compounds. Recently many efforts have been made in recycling of the wastewater. Different physical and chemical methods have been developed for the removal of contaminant, especially heavy metals from the wastewater, some of whic...
Article
Full-text available
Obesity is a complex disorder which is characterised by excessive accumulation of adipose tissue and is linked to many health problems including cardiovascular disease. Green tea has anti-oxidant properties and has been shown to be beneficial for reducing obesity measures such as waist to hip ratio and fat mass. Physical activity and particularly a...
Article
Full-text available
Introduction Antioxidants are health beneficial compounds that can protect cells and macromolecules from the damage of reactive oxygen species (ROS). The aims of this study were to compare the total antioxidant and carotenoid production in R. Slooffiae and R. Mucilaginosa. Methods To isolate the carotenoid pigment, cells were suspended in acetone...
Article
Background: Collagen, the most abundant protein in the human body, and as an extracellular matrix protein, has an important role in the fiber formation. This feature of the collagen renders establishment of the structural skeleton in tissues. Regarding specific features associated with the collagen, such as, formation of the porous structure, perm...
Article
Full-text available
Background and Objectives : Chemerin is a newly discovered adipokine, which induce insulin resistance in skeletal muscles. The present study examined the secretion rate of plasma chemerin and its effect on insulin resistance index after 8 weeks of resistance exercise in male rats. Methods: In this study, 24 male Wister rats (mean weight, 161±23g an...
Article
Full-text available
To find out whether or not soy milk as a phytoestrogen product can improve the quality of life of the Iranian postmenopausal women. Participants of this randomized clinical trial were 57 healthy postmenopausal women. All eligible women were randomly divided into two groups of soy milk (SG) and control (CG). Individuals in the SG (n = 34) received 5...
Article
Full-text available
Exercise (EEE). Experimental groups EEE and HIE Respectively were performed Bruce Protocol Treadmill Stress Test and Running-based Anaerobic Sprint Test (RAST) repeat 3 times with 3 min active rest.Venous blood samples were obtained for analysis before and after 1 hour's last exercise. Results: The result of this study indicated that SGOT (F2, 15 =...
Article
Full-text available
Introduction: The hormonal changes that happen during pregnancy may have effects on weight, blood pressure, dyslipidaemia, and possibly metabolic syndrome. The aim of this study was to determine the association between parity and metabolic syndrome in middle-aged women in Babol, Iran. Methods: A total number of 800 women, with the age range of 30...
Article
Full-text available
Introduction: The purpose of this study was to effect of six weeks of resistance training (RT) and silymarin supplement on the changes in the inflammation marker interleukin 6 and psychological profile in elite female Taekwondo players in Alborz province. Materials and Methods: forty elite female Taekwondo players (aged 18-22 years) participate in...