Papiya Roychowdhury

• Doctor of Medicine(MD)
• Programme officer at Dist head quater,India Barasat

Background Elder abuse is still underreported and unacknowledged despite being a serious social concern linked to significantly higher rates of hospital admission and mortality. Abuse has a profound effect on the victims' physical, mental, and overall quality of life. Abuse can worsen an elderly person's preexisting chronic and incapacitating disea...

Introduction: During the refining and packing of tea, a very fine dust is formed which is called the tea fluff. Exposure to this fluff has been reported to cause ventilatory defects on chronic exposure. Objective: To determine the association between air quality of the different work sections of tea gardens and the ventilatory functions of the w...

Vital capacity, frequently measured clinically as an index of pulmonary function, gives useful information about the strength of respiratory muscles and other aspects of lung functions. It is generally noted in sitting position. As in the supine position, respiratory excursions of diaphragm is highest in normal breathing, this study was planned to...

The present study was undertaken to assess the difference between the normal predicted value and observed value of pulmonary function test (PFT) amongst the asthmatic patients and also to compare the aforesaid observed values between male and female asthmatic patients. Clinically diagnosed cases (male 62, female 75) of bronchial asthma attending me...

Background: Early detection of proneness to hypertension may help an individual to lead a healthy life by altering the life style. Subjects having the predisposing factors of hypertension tend to show higher and prolonged responsiveness to blood pressure following stress. Methods: Normotensive, non-smoking healthy sedentary male students and staff...

Some pulmonary function tests along with cardio respiratory fitness test were performed to assess the health status of the young (19-21 years) non-smokers Nepalese medical students. Results revealed that the vital capacity was 3.46 liters and 2.40 liters among the boys and girls respectively. PEFR was found to be 597.98 l/min among the boys and 456...

Study habits and attitude for learning of Basic Medical Sciences amongst 133 students of first and second year MBBS course were analyzed (through questionnaires). The study revealed that the most of the students desired to be physicians to serve the patient/society. They preferred to learn more through self study (48.0%) and lecture classes (43.0%)...

Intra­molecular hydrogen bonds influence the mol­ecular conformation of the title compound, C10H19N5O, resulting in an extended planar hydrogen-bonded heterocyclic ring structure. The bulky diethyl­amino­ethyl group adopts a butterfly conformation. The stabilization of the crystal structure is supported by an extensive network of inter­molecular hy...

The title compound, C12H13N4⁺·C7H7O3S⁻, contains an imidazolium cation and a toluene-p-sulfonate anion in the asymmetric unit. Hydrogen-bonded dimers are formed between the cyano and amino groups of inversion-related imidazolium cations.

Anxiety can alter the cardiovascular parameters. In the present study, among the normotensive donors, the effect of anxiety on alteration of blood pressure and heart rate was assessed. Blood pressure and pulse rate were recorded in the volunteers just before blood donation and the results were compared with the blood pressure and heart rate recorde...

The title compound, tetra­sodium bis­[tris­(salicylato­titanate(IV)] undeca­hydrate, Na4[Ti(C7H4O3)3]2·11H2O, crystallizes with two titanium salicylate complex ions, four sodium ions and 11 water mol­ecules in the asymmetric unit. One water O atom is disordered over two positions, having 0.74 (5) and 0.26 (5) occupancy. Both Ti atoms and three sodi...

The title compound, C21H28O4, a synthetic glucocorticoid, crystallizes with a single mol­ecule in the asymmetric unit. Ring A is almost in a half-chair conformation, rings B and C are almost in chair conformations, and ring D is between a twist and a 13β-envelope conformation. The A/B ring junction is quasi-trans, whereas the B/C and C/D ring junct...

The title compound, C21H28O4, a synthetic glucocorticoid, crystallizes with a single mol­ecule in the asymmetric unit. Ring A is almost in a half-chair conformation, rings B and C are almost in chair conformations, and ring D is between a twist and a 13β-envelope conformation. The A/B ring junction is quasi-trans, whereas the B/C and C/D ring junct...

In this study, the variation of blood pressure in young normotensive medical students has been recorded in winter and summer. Daytime blood pressure of young normotensive medical students has been measured in supine position. It has been found that both the systolic and diastolic pressure increases in low ambient temperature. It may be due to sympa...

Corticosteroid binding globulin (CBG) and thyroxin binding globulin (TBG) both belong to the same SERPIN superfamily of serine–proteinase inhibitors but in the course of evolution CBG has adapted to its new role as a transport agent of insoluble hormones. CBG binds corticosteroids in plasma, delivering them to sites of inflammation to modify the in...

Mineralocorticoids play a major role in regulating sodium and potassium homeostasis and also contribute to the control of blood pressure and in some physiological disorders. The physiological effects of this class of corticosteroids are mediated by ligand-induced nuclear transcription factor, the mineralocorticoid receptor(MR) / glucocorticoid rece...

Glucocorticoids are involved in the growth, development and homeostasis of a number of tissues. The physiological effects of this class of lipophilic steroids are mediated by ligand-inducible nuclear transcription factor, the glucocorticoid receptor/mineralocorticoid receptor, a member of the steroid/nuclear receptor superfamily. The glucocorticoid...

Synthetic steroid de-oxy corticosterone (4-pregnen-21-ol-3,20-dione) crystallizes in the monoclinic space group P21, with a � 11.706(2); b � 11.171(3), c � 13.966(3)A° , and � � 100.94(2)�, Z � 4. Ring A tends to acquire the conformation of a half-boat, rings B and C are in the chair configuration, and ring D is a 13�, 14�-half-chair. The ring junc...

Synthetic steroid de-oxy corticosterone (4-pregnen-21-ol-3,20-dione) crystallizes in the monoclinic space group P21, with a = 11.706(2); b = 11.171(3), c = 13.966(3)A° , and beta = 100.94(2) A°, Z = 4. Ring A tends to acquire the conformation of a half-boat, rings B and C are in the chair configuration, and ring D is a 13 beta, 14 alpha-half-chair....

Both 5-amino-1-(2-hydroxyethyl)imidazole-4-carboxamide (AHIC) and 5-amino-1-(2-chloroethyl)-4-cyanoimidazole (ACCI) have been synthesized and crystallized in the monoclinic space group P21/c, Z = 4, with a = 8.420(2), b = 9.759(2), c = 10.583(2) , = 111.80(2) for AHIC and a = 6.139(1), b = 8.522(2), c = 15.156(3) , = 96.71(2) for ACCI. Differences...

Synthetic steroid de-oxy corticosterone (4-pregnen-21-ol-3,20-dione) crystallizes in the monoclinic space group P21, with a = 11.706(2); b = 11.171(3), c = 13.966(3) Å, and ß = 100.94(2)°, Z = 4. Ring A tends to acquire the conformation of a half-boat, rings B and C are in the chair configuration, and ring D is a 13ß, 14a-half-chair. The ring junct...

Synthetic glucocorticoid de-oxy corticosterone-21-hemisuccinate crystallizes in the monoclinic space group C2, with a = 21.896(2), b = 7.596(3) and c = 14.291(3) A° , Z = 4. Ring A is a distorted half chair, ring B and C are in the chair configuration and ring D is in the 14 alpha-half chair configuration. The ring junctions B/C and C/D are both tr...

The population of total bacteria, fungi, nitrogen fixing bacteria and phosphorus solubilising microorganisms increased with fluvalinate treatment, but the same treatment decreased actinomycetes population. Lower dose of fluvalinate significantly increased the population of thiosulphate oxidising bacteria while higher dose showed a non-significant e...

The coordination mode of the title ligand, HMPzSB (synthesized for the first time and characterised by elemental analysis, mass, IR and PMR spectral parameters), is reported by solid state isolation and physicochemical identification of cobalt(III) complexes, [Co(MPzSB)2]X (X = Cl, ClO4 and BF4). Electronic spectral features of these diamagnetic Co...

The title copper(I) complex of a substituted pyrimidyl hydrazone has been synthesized and characterized by X-ray diffraction. The structure has been shown to contain one central Cu atom bonded to four N atoms in a tetrahedral geometry with two hydrazinic N atoms and two pyrimidyl ring N atoms. The structure also proves that the pyrimidine ring and...

Each Cu-II ion in [{Cu(H2O)}2(mu-C10H11N2O5S)(4)].4H(2)O, (II), is coordinated to its centrosymmetric counterpart, the equatorial carbonyl and carboxylic O atoms of two N-benzenesulfonylglycylglycinate moieties and their centrosymmetric counterparts and to an axial water O atom. The centrosymmetrically related Cu-II ions are linked by bridges of 2....

In the title compound, 2Na[Mo2O4(C10H12N2O8)].-4H(2)O, the hexadentate ethylenediaminetetraacetate (edta) ligand coordinates to each Mo atom through two carboxylate O atoms and an N atom while two bridging O atoms and a terminal O atom complete the coordination sphere around each Mo centre.

Jatrorrhizine is a naturally occurring antimalarial alkaloid. The structure of jatrorrhizine, determined from its chloride (5,6-dihydro-3-hydroxy-2,9,10-trimethoxydibenzo[a,g]quinolizinium chloride dihydrate), consists of four fused rings. The conformation of ring I (benzo) is a boat and ring II (dihydropyrido moiety) is deviated from its twist-boa...

C17H16N4O, M(r) = 292.34, monoclinic, P2(1)/a, a = 12.325 (1), b = 22.303 (2), c = 11.3682 (9) angstrom, beta = 100.015 (7)-degrees, V = 3077.3 (5) angstrom 3 Z = 8, D(m) = 1.283 (by flotation in benzene-bromoform), D(x) = 1.262 g cm-3, lambda-(Cu K-alpha) = 1.5418 angstrom, mu-(Cu K-alpha) = 6.230 cm-1, R = 0.045 for 3876 observed reflections. The...

The crystal structure of 2-(5-amino-4-carboxamidoimidazol-1-yl)acetamide has been determined from X-ray diffractometric data, and refined to anR-value of 0.057 with 1179 observed reflections. Intramolecular hydrogen bonding between the 5-amino group and the vicinal carboxamide moiety stabilizes the molecular conformation and forms an extended plana...

The importance of a precise structure and conformation analysis of the title compound (I) (space group P21 with Z=4) arises from its neuromuscular blocking action.

C21H23N2O2+.Cl-.1.5H2O, Mr = 397.90, monoclinic, P2(1), a = 7.617 (1), b = 32.463 (2), c = 7.849 (1) A, beta = 90.40 (2) degrees, V = 1940.8 (4) A3 Z = 4, Dm = 1.39, Dx = 1.36 g cm-3, lambda (Cu K alpha) = 1.5418 A, mu = 19.724 cm-1, F(000) = 844, final R = 0.047 for 3368 observed reflections. Strychnine hydrochloride is a naturally occurring alkal...

Troponin C is the Ca 2+ -binding subunit of the troponin complex and is involved in the calcium control of muscle contraction. The X-ray structure of chicken TnC has been determined at 3Å resolution using a single heavy atom derivative and application of a novel phase improvement and phase extension procedure. The protein has an unusual dumbbell- s...

Cristallisation dans P2 1 avec Z=2; affinement jusqu'a R=0,062. La molecule est legerement deformee a partir d'une structure plane par suite du surencombrement intramoleculaire. Les distances entre les atomes H surencombres sont 1,87; 1,88 et 1,89 A, environ 0,5 A en dessous des distances de van der Waals habituelles

The x-ray structure of chicken skeletal muscle troponin C (TnC), the Ca2+-binding subunit of the troponin complex, shows that the protein is about 70 angstroms long with an unusual dumbbell shape. The carboxyl and amino domains are separated by a single long alpha helix of about nine turns. Only the two high-affinity Ca2+-Mg2+ sites of the COOH-dom...