Pantelis Maiovis

• MD, MSc, PhD
• Research Associate at AHEPA University Hospital

Background and objective: Cognitive reserve (CR) mediates the clinical expression of brain pathology in Alzheimer's disease, while there are much less relevant data in frontotemporal dementia (FTD). In the present study we examined whether CR, measured using the Cognitive Reserve Index (CRI), correlated with regional cerebral blood flow (rCBF) in...

Severity assessment scales for frontotemporal lobar degeneration (FTLD) have been recently introduced. In the present study, the authors examined whether the FTLD-modified Clinical Dementia Rating (FTLD-CDR) scale and the Frontotemporal Dementia Rating Scale (FRS) correlated with regional brain perfusion in Greek FTLD patients. A total of 47 behavi...

Cognitive reserve (CR) is thought to reflect the cumulative brain potential derived from various cognitively demanding activities throughout the entire life. It seems to mediate both one’s cognitive performance and clinical expression of different brain pathologies, such as Alzheimer’s disease. Many researchers have tried to assess CR by using prox...

Concomitant central nervous system (CNS) involvement in chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) is rare. Although the spinal nerve roots may present MRI abnormalities in CIDP, hitherto, the spinal cord has been investigated in a single study. We retrospectively investigated clinically and with MRI a cohort of patients with...

Early onset dementia (EOD) is a major diagnostic challenge as it often presents with atypical features and may be attributed to treatable diseases. Primary degenerative dementias (Alzheimer's disease-AD, frontotemporal lobar degeneration-FTLD, Lewy body dementia-LBD), although traditionally considered to affect older people, are still a main cause...

We present the case of a 66 year-old man referred for evaluation of quadriparesis with marked sensory and autonomic involvement. His illness started 18 months ago with gradually worsening paresthesias and numbness in the hands and feet. He was diagnosed with chronic inflammatory demyelinating polyradiculoneuropathy, treated with immunoglobulin G bu...

Frontotemporal lobar degeneration (FTLD) comprises of behavioral variant frontotemporal dementia (bvFTD) and primary progressive aphasia (PPA) with its 3 main variants, namely nonfluent/agrammatic (naPPA), semantic (svPPA) and logopenic (lvPPA). Recently a clinical syndrome with predominant right temporal atrophy was recognized (rvFTD). FTLD often...

We report the first Greek case of autoimmune autonomic ganglionopathy seropositive for antibodies against ganglionic acetylcholine receptors, unique for an antecedent viral cerebellitis and long, slowly progressive course, with improvement after treatment with pyridostigmine.

Η έννοια του κοινωνικού κεφαλαίου συνίσταται στην ύπαρξη δικτύων στην κοινότητα, στη συμμετοχή των πολιτών στα κοινά, στην πρόσβαση σε άτυπα ή θεσμικά δίκτυα πληροφόρησης και ενημέρωσης, στην ανταποδοτικότητα και την εμπιστοσύνη μεταξύ των ατόμων. Τα τελευταία χρόνια έχει αρχίσει να παρουσιάζει αυξανόμενο ενδιαφέρον μεταξύ των ερευνητών στο χώρο τη...

Current trends in dementia research focus on early and accurate diagnosis. In clinical practice however, this is not always possible, as multiple underlying pathologies produce mixed dementia syndromes. Furthermore, patients with severe dementia are often underestimated. We present a case of a 71 year old Caucasian male with severe Alzheimer's Dise...