Pandji Wibawa Dhewantara

National Research and Innovation Agency · Health Research Division

Abstract Human leptospirosis outbreaks still persistently occur in part of China, indicating that leptospirosis remains an important zoonotic disease in the country. Spatiotemporal pattern of the high-risk leptospirosis cluster and the key characteristics of high-risk areas for leptospirosis across the country are still poorly understood. Using spa...

Background: Although the association between dengue in Bali, Indonesia, and imported dengue in Australia has been widely asserted, no study has quantified this association so far. Methods: Monthly data on dengue and climatic factors over the past decade for Bali and Jakarta as well as monthly data on imported dengue in Australia underwent a thre...

Background: Malaria remains a significant public health concern in Indonesia. Knowledge about spatial patterns of the residual malaria hotspots is critical to help design elimination strategies in Kotabaru district, South Kalimantan, Indonesia. Methods: Laboratory-confirmed malaria cases from 2012 to 2016 were analysed to examine the trend in ma...

The Special Capital Region of Jakarta is the epicentre of the transmission of COVID-19 in Indonesia. However, much remains unknown about the spatial and temporal patterns of COVID-19 incidence and related sociodemographic factors explaining the variations of COVID-19 incidence at local level. COVID-19 cases at the village level of Jakarta from Marc...

Climate is widely known as an important driver to transmit vector-borne diseases (VBD). However, evidence of the role of climate variability on VBD risk in Indonesia has not been adequately understood. We conducted a systematic literature review to collate and critically review studies on the relationship between climate variability and VBD in Indo...

Background Climate change, leading to more frequent and intense extreme weather events (EWEs), could significantly impact dengue transmission. However, the associations between EWEs and dengue remains underexplored in the Southeast Asia (SEA) region. We investigated the association between selected EWEs (i.e. heatwaves, extremely wet, and drought c...

Objectives: Prospective studies on vaccination status and mortality related to coronavirus disease 2019 (COVID-19) in low-resource settings are still limited. We assessed the association between vaccination status (full, partial, or none) and in-hospital mortality among COVID-19 patients at most hospitals in Jakarta, Indonesia during the Delta pred...

Leptospirosis is neglected in many tropical developing countries, including Indonesia. Our research on this zoonotic disease aimed to investigate epidemiological features and spatial clustering of recent leptospirosis outbreaks in Pangandaran, West Java. The study analysed data on leptospirosis notifications between September 2022 and May 2023. Glo...

Climate change is known to have a significant impact on public health as it could speed the spread of zoonotic infections. The purpose of this study is to estimate the potential geographical distribution of the risk of leptospirosis – a bacterial infection caused by Leptospira spp and transmitted by rodents, in Western Java islands. The possible di...

Leptospirosis is a common bacterial infection caused by pathogenic Leptospira spp.in tropical region, including inIndonesia. During the first year of COVID-19 pandemic, Jakarta reported a significant increase in leptospirosis cases.A study was conducted to analyze the distribution of leptospirosis and to identify hotspots of the leptospirosis.Lepto...

The study describes the demographics, clinical characteristics, vaccination history of adult patients with COVID-19 and to estimate risk for in-hospital mortality among patients admitted during the peak of Delta outbreak in Jakarta. Available at SSRN: https://ssrn.com/abstract=4095250

Background Inactivated SARS-CoV-2 vaccine has been included in the national COVID-19 vaccination program in Indonesia since January 2021. The study aims to estimate the effectiveness of CoronaVac vaccine in preventing SARS-CoV-2 infection, hospitalization, and death in adult population aged ≥18 years in Bali, Indonesia. Methods Test-negative, case...

Indonesia has rich Anopheline (Diptera: Culicidae) mosquito species living in various types of ecosystems. The study was conducted to profile and compare Anopheles diversity, equitability, and dominance in various ecosystems using different animal-based sampling techniques. The present study analyzed a subset of data collected from a nation-wide ve...

The distribution of LLINs (Long Lasting Insecticidal Nets) is one of the strategies implemented by health programs to control malaria in Indonesia. This study aims to determine the sociodemographic factors associated with the use of LLINs. The research is an observational with a cross-sectional study design. Interviews using a structured questionna...

The World Health Organization (WHO) has been implementing antimicrobial surveillance with a “One Health” approach, known as the Global Surveillance ESBL E. coli Tricycle Project. We describe the implementation of the Tricycle Project (pilot) in Indonesia, focusing on its results, challenges and recommendations. ESBL E. coli was identified in 116 bl...

This study was conducted to quantify the trend in dengue notifications in the country in 2017 and to explore the possible determinants. Annual nation-wide dengue notification data were obtained from the National Disease Surveillance of Ministry of Health of Indonesia. Annual incidence rate (IR) and case fatality rate (CFR) in 2017 and the previous...

The aim of this study was to assess the role of climate variability on the incidence of dengue fever (DF), an endemic arboviral infection existing in Jakarta, Indonesia. The work carried out included analysis of the spatial distribution of confirmed DF cases from January 2007 to December 2018 characterising the sociodemographical and ecological fac...

Background Integrating and scaling up tuberculosis (TB) and HIV services are essential strategies to achieve the combined goals ending both TB and HIV, especially in TB and HIV high burden countries. This study aimed to examine the prevalence of TB and HIV co-infection and the implementation of collaborative services in Ethiopia. Methods We used a...

Background: Small mammals such as rats and bats are important animal reservoirs of various zoonotic diseases of public health importance. The potential of rats and bats as a reservoir of leptospirosis and Japanese Encephalitis (JE) in Muna Regency remains unknown. This study aimed to determine the presence of Leptospira spp and JE virus (JEV) in ra...

Despite the improvement of control efforts, dengue fever (OF) remains a significant public health issue in Jakarta. While spatial analytical approaches offer a promising alternative to support disease control and surveillance, it remains poorly utilized in understanding DF patterns in Jakarta. This study aimed to use geostatistical tools to investi...

The Indonesian government has instituted annual mass drug administration (MDA) of diethylcarbamazine (DEC) and albendazole in filarial endemic districts in West Sumatera, Indonesia to control this disease but adverse drug reactions can influence the uptake of the medication by the target population. In this study, we aimed to determine the types an...

The Indonesian government has instituted annual mass drug administration (MDA) of diethylcarbamazine (DEC) and albendazole in filarial endemic districts in West Sumatera, Indonesia to control this disease but adverse drug reactions can influence the uptake of the medication by the target population. In this study, we aimed to determine the types an...

The aim of this study was to assess the possible association of El Niño Southern Oscillation (ENSO) and Dipole Mode Index (DMI) on chikungunya incidence overtime, including the significant reduction in cases that was observed in 2017 in Indonesia. Monthly nation-wide chikungunya case reports were obtained from the Indonesian National Disease Survei...

The unsafe and improper use of household insecticides represents a major hazard to the environment and human health. Most of people in Pangandaran Sub-District used household insecticides, even more than ten years. The aim of this study was to analyse factors that affect in safety practices of using household insecticide. The research was conducted...

Background Geographical variation may likely influence the effectiveness of prevention efforts for malaria across Indonesia, in addition to factors at the individual level, household level, and contextual factors. This study aimed to describe preventive practices at individual and a household levels applied by rural communities in five provinces in...

Background Since 2011 human leptospirosis incidence in China has remained steadily low with persistent pockets of notifications reported in communities within the Upper Yangtze River Basin (UYRB) and Pearl River Basin (PRB). To help guide health authorities within these residual areas to identify communities where interventions should be targeted,...

The re-emergence of Brugian filariasis after mass drug administration (MDA) has been documented in Indonesia. A third-round of transmission assessment survey (TAS) in Kotawaringin Barat district revealed positive anti-Brugia IgG4 antibodies in humans, indicating a newly emerged Brugian filariasis transmission. Yet, recent microfilaria (Mf) status i...

Background: Dengue fever control in the tropical island of Bali in Indonesia carries important significance both nationally and globally, as it is one of the most endemic islands in Indonesia and a worldwide popular travel destination. Despite its importance, the spatial and temporal heterogeneity in dengue risk and factors associated with its var...

Objective To quantify the effects of climate variability, selected remotely-sensed environmental factors on human leptospirosis in the high-risk counties in China.IntroductionLeptospirosis is a zoonotic disease caused by the pathogenic Leptospira bacteria and is ubiquitously distributed in tropical and subtropical regions. Leptospirosis transmissio...

Background: In the past three decades, the incidence rate of notified leptospirosis cases in China have steeply declined and are now circumscribed to discrete areas in the country. Previous research showed that climate and environmental variation may play an important role in leptospirosis transmission. However, quantitative associations between c...

Abstract Background The recent situation of dengue infection in Cirebon district is concerning due to an upsurge trend since the year 2010. The largest dengue outbreak was reported in 2016 which has affected more than 1600 children. A study was conducted to explore the temporal variability of dengue outbreak in Cirebon’s child population in during...

Background Malaria is still an important parasitic infectious disease that affecting poor and vulnerable communities in many developing countries, including Indonesia. During the period of 2010–2017, there have been approximately 2.2 million confirmed malaria cases reported across Indonesia. This study aimed to identify individual, household and vi...

Leptospirosis is a global zoonotic disease that the transmission is driven by complex geographical and temporal variation in demographics, animal hosts and socioecological factors. This results in complex challenges for the identification of high‐risk areas. Spatial and temporal epidemiological tools could be used to support leptospirosis control p...

Abstract Background Leptospirosis morbidity and mortality rates in China have decreased since the 2000s. Further analyses of the spatiotemporal and demographic changes occurring in the last decade and its implication on estimates of disease burden are required to inform intervention strategies. In this study, we quantified the epidemiological shift...

Abstrak. Data entomologis terkait aspek bionomik dan distribusi nyamuk vektor lymphatic filariasis di Kabupaten Bandung masih sangat sedikit meskipun kabupaten ini sudah mengimplementasikan POPM Filariasis dari tahun 2009. Tujuan penelitian adalah mengindentifikasi spesies nyamuk potensial penular lymphatic filariasis dan habitatnya di wilayah ende...

Ecological Niche Modelling (ENM) was applied to produce suitability maps of Leptospira transmission in Western Java under current and future climate scenarios.

Dengue control in Indonesia could be threatened by theexistence of Aedes spp resistance on insecticides. This could be the one of the determinants of dengue fever incidence that makes the mortality and morbidity remains high in Indonesia for over last decades. Since 1980, pyrethroid synthetic insecticide (i.e permethrin, deltamethrin, and malathion...

Malaria cases in Banten Province remains high in two districts, Pandeglang and Lebak. Yet, knowledge and information about vector capacity in this region is still unclear. Our study was aimed to determine the vector capacity and entomological inoculation rate of Anopheles vagus in endemic regions in Banten. A cross-sectional survey was conducted f...

Four dengue serotypes threatened more than 200 million people and has spread to over 400 districts in Indonesia. Furthermore, 26 districts in most densely populated province, West Java, have been declared as hyperendemic areas. Cimahi is an endemic city with the highest population (14,969 people per square kilometer). Evidence on distribution patte...

Indonesia is targeted to be free of malaria in 2030 and its success is determined by the effectiveness of treatment. Riskesdas 2013 shows the effective treatment of malaria rate as 45.5%. Nationally, only 33.7% of malaria patients received the Artemisinin-based Combination Therapy (ACTs). A further analysis to Riskesdas 2013 data was performed to d...

Indonesia is targeted to be free of malaria in 2030 and its success is determined by the effectiveness of treatment. Riskesdas 2013 shows the effective treatment of malaria rate as 45.5%. Nationally, only 33.7% of malaria patients received the Artemisinin-based Combination Therapy (ACTs). A further analysis to Riskesdas 2013 data was performed to d...

One of the risk factors of dengue incidence is the availability of vector breeding sites. In 2012, a cross-sectional analytical observation was conducted on 100 households with DHF in Banjar. The aim of this study was to determine the household risk level through Maya Index approach. The data collected includes the type and number of containers, as...

Background: Intensive use of chemical insecticides not only affect the target species, but also non-target species and environment. In this study, we examined residual effect of deltamethrin on cockroaches (Periplaneta americana), catfi shes (Clarias batrachus) and nile-tilapia (Oreochromis niloticus). In addition, we aimed to measure the infi ltra...

Essential oil are now widely studied as an alternative way to control mosquitoes whether as a repellent and also as a biolarvicide. Several studies had shown that essential oil from betel leaf (Piper betle L.) has the potential to control the development of Aedes aegypti larvae, but it remains has a limitation, which is its short durability. To...

Background: Malaria remains as potentially re-emergent disease in Sukaresik village, Pangandaran, West Java. Information of vectorial capacity (C), entomological inoculation rate (EIR), and stability index (SI) of well-known malaria vector in this area, Anopheles sundaicus, was limited and rarely published. A further analysis of spot-survey result...

Sukaresik village Sidamulih Sub-District Ciamis remains as an area with high risk malaria in West Java. Studying vector bioecology on a region is important to support vector and disease control. A spot-survey study had been conducted during September-November 2011 in order to obtain vector bioecology information in Sukaresik village, Ciamis, i.e br...