Panagiotis Kalozoumis

University of Thessaly | UTH · Department of Computer Science and Biomedical Informatics

Introduction: Synthetic vascular grafts perform poorly in small-caliber (<6mm) anastomoses, due to intimal hyperplasia and thrombosis, whereas homografts are associated with limited availability and immunogenicity, and bioprostheses are prone to aneurysmal degeneration and calcification. Infection is another important limitation with vascular graft...

The assistive navigation of visually impaired individuals requires the development of different algorithms for obstacle detection, recognition, avoidance, and path planning. The assessment and optimization of such algorithms in the real world is a painstaking process that requires repetitive measurements under stable conditions, which is usually di...

Endoscopic medical devices enable minimally invasive visual screening and medical interventions in the human body. The development of such devices typically requires evaluation stages involving time- and resource-demanding in vivo animal studies and clinical trials, associated with ethical and safety considerations. The computational modeling of bi...

Extracorporeal membrane oxygenation (ECMO) has been used clinically for more than 40 years as a bridge to transplantation, with hollow-fiber membrane (HFM) oxygenators gaining in popularity due to their high gas transfer and low flow resistance. In spite of the technological advances in ECMO devices, the inevitable contact of the perfused blood wit...

Every day, visually challenged people (VCP) face mobility restrictions and accessibility limitations. A short walk to a nearby destination, which for other individuals is taken for granted, becomes a challenge. To tackle this problem, we propose a novel visual perception system for outdoor navigation that can be evolved into an everyday visual aid...

Cardiac valves, and especially the mitral valve (MV), are complex anatomical structures. Their proper function depends on a delicate force distribution and synchronized function of all their components. Pathological changes in valve components are common indicators for valvular surgery. There is a large variety of valve implants (mechanical/ biolog...

Decellularized scaffolds represent a promising alternative for mitral valve (MV) replacement. This work developed and characterized a protocol for the decellularization of whole MVs. Porcine MVs were decellularized with 0.5% (w/v) SDS and 0.5% (w/v) SD and sterilized with 0.1% (v/v) PAA. Decellularized samples were seeded with human foreskin fibrob...

Abstract Objective: Blend electrospinning has been acknowledged as a cost-effective technique for the production of fibrous scaffolds, suitable for various biomedical applications. Coaxial electrospinning is a method variant that results in core-shell structures with advantages, such as delayed diffusion and protection of sensitive biomolecules. Th...

Atherosclerosis is a major cause of morbidity and mortality and is result of complex relations among blood, flow parameters and vessel geometry. Its apparent link to wall shear stress (WSS) has led to considerable interest in the in vivo estimation of WSS. An automated method is described for creating a computational fluid dynamic (CFD) mesh of a b...

This paper presents the initial phases of the design and development of a laboratory scale facility for the characterization of the intraocular pressure in the human eye. The development phase included the mechanical design of the various parts of the facility. Several manufacturing techniques have been employed including multi-axes computer aided...