Pamoda Jayatunga

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Verified

Pamoda verified their affiliation via an institutional email.

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• BSc (University of Colombo) PhD (Edith Cowan University - Australia)
• Senior Lecturer at University of Sri Jayewardenepura

Aedes aegypti is the primary dengue vector in Sri Lanka that causes the massive public health problem of Dengue Fever (DF) and Dengue Hemorrhagic Fever (DHF) on the island. It is an anthropophilic mosquito that shows preferential feeding depending on the host blood type. Hence, the study was conducted to investigate the effects of human ABO and Rh...

Dengue is a fast-spreading mosquito-borne viral disease in the world. The primary vector of the disease is Aedes aegypti of the family Culicidae. It is a container breeder. Since a vaccine or a drug has not been developed against dengue, vector control appears to be the best method so far to control dengue. The current study was conducted to determ...

Evidence to date suggests the consumption of food rich in bioactive compounds, such as polyphenols, flavonoids, omega-3 fatty acids may potentially minimize age-related cognitive decline. For neurodegenerative diseases, such as Alzheimer's disease (AD), which do not yet have definitive treatments, the focus has shifted toward using alternative appr...

Alzheimer’s disease (AD) is a devastating neurodegenerative disorder and the most common form of dementia worldwide. The classical AD brain is characterized by extracellular deposition of amyloid-β (Aβ) protein aggregates as senile plaques and intracellular neurofibrillary tangles (NFTs), composed of hyper-phosphorylated forms of the microtubule-as...

Leishmaniasis is a fatal disease caused by a parasitic protist of the genus Leishmania through the infected primary vectors, Phlebotomine (Diptera: Psychodidae) female sand flies. In Sri Lanka, cutaneous leishmaniasis (CL) is established in Anuradhapura district. The present study was carried out to determine the socio-economic and environmental fa...

Mitochondrial dysfunction including deficits of mitophagy is seen in aging and neurodegenerative disorders including Alzheimer’s disease (AD). Apart from traditionally targeting amyloid beta (Aβ), the main culprit in AD brains, other approaches include investigating impaired mitochondrial pathways for potential therapeutic benefits against AD. Thus...

Simple Summary Commonly known as the Asian tiger mosquito, Aedes albopictus is a vector of dengue worldwide. Knowledge of the behavior of dengue vectors facilitates effective vector control. This is the first comprehensive analysis of selected vertebrate excreta of goat, cow and pig to identify the oviposition attraction and growth performance of A...

Mosquito species Aedes aegypti and Aedes albopictus are vectors of dengue worldwide. Mosquito vector control through maintaining larvivorous fish in water bodies is generally suggested, however, its underlying role towards oviposition preference of these dengue vectors is unknown in the Sri Lankan context. The current study investigated the effect...

The mosquito Anopheles (Cellia) subpictus sensu lato (s.l.) is a major secondary vector of malaria in Sri Lanka. The sibling species composition in this species complex in Sri Lanka remains debatable. Compensatory base changes (CBCs) in the secondary structures of internal transcribed spacer 2 (ITS2) are reliable sources to predict sexual incompati...

Alzheimer’s disease (AD) is a devastating neurodegenerative disorder that affects approximately 60-80% of all clinically diagnosed dementia cases worldwide. It is the second major cause of death in Australia. The progressive nature of the disease is characterized by cognitive deficits that worsen over time, usually leading to death within about a d...

Mitochondria perform many essential cellular functions including energy production, calcium homeostasis, transduction of metabolic and stress signals, and mediating cell survival and death. Maintaining viable populations of mitochondria is therefore critical for normal cell function. The selective disposal of damaged mitochondria, by a pathway know...

Background: Alzheimer’s disease (AD) is a devastating neurodegenerative disorder that affects approximately 60-80% of all clinically diagnosed dementia cases worldwide. The progressive nature of the disease is characterized by cognitive deficits that worsen over time, leading to death within about a decade from their first manifestation. The AD bra...

Neurodegenerative diseases result in a range of conditions depending on the type of proteinopathy, genes affected or the location of the degeneration in the brain. Proteinopathies such as senile plaques and neurofibrillary tangles in the brain are prominent features of Alzheimer’s disease (AD). Autophagy is a highly regulated mechanism of eliminati...

Evidence suggests that diets rich in antioxidants reduce the risk factors of Alzheimer’s disease (AD). Hippophae rhamnoides, commonly known as sea buckthorn (SB), is rich in antioxidants which could have direct effects on amyloid‐beta (Aβ) levels and consequently influence AD pathogenesis. In this study, sea buckthorn powder (SBP) was administered...

Dengue is a fatal arthropod-borne disease that affects humans worldwide. The mosquito Aedes albopictus (Skuse) is the secondary vector of dengue in Sri Lanka, however, studies on oviposition preferences of Ae. albopictus is scarce. The objective of the current study was to investigate the oviposition attraction of Aedes albopictus to selected house...

Background Luteolin, a flavone compound found in various foods has shown beneficial effects for Alzheimer's disease (AD) due to anti‐inflammatory and anti‐oxidant activities (Kwon et al., 2017). Decosahexaenoic acid (DHA) is an essential long‐chain omega‐3 polyunsaturated fatty acid naturally occurred in healthy brains, however, there is evidence f...

Background Alzheimer's disease (AD) is characterised by abnormal deposition of the amyloid‐β protein (Aβ) in the brain which plays a major role in AD pathogenesis and is one of the major targets for developing therapeutic agents. Evidence suggests that diets rich in antioxidants reduce the risk factors of AD. Hippophae rhamnoides, commonly called s...

The species complex of the mosquito Anopheles subpictus is designated by the sibling species A–D, depending on morphological characters of life cycle stages and variations in polytene chromosomes. However, morphological aberrations in the life cycle stages make the identification of sibling species uncertain and imprecise. The objective of the pres...

Anopheles culicifacies Giles s.l., the primary vector of malaria in Sri Lanka comprises a complex of five sibling species as A,B,C,D and E. Among them only sibling species B and E are found in Sri Lanka. Sibling species of the complex are morphologically identical and varies in vectorial capacity. Molecular characterization of the vector species is...

Anopheles subpictus sensu lato is an important secondary vector of malaria in Sri Lanka. Molecular phylogenetic studies using Internal Transcribed Spacer 2 (ITS2) and Cytochrome c Oxidase subunit-1 (COI) gene have identified two sibling species An. subpictus A and B in Sri Lanka. The objective o f the present study was to further investigate and co...

A mosquito survey was carried out for 8 months between October 2009 and May 2010 in 12 randomly selected urban (6) and semi-urban (6) areas in the Colombo District of Sri Lanka. Thirty eight mosquito species were identified from which Anopheles interruptus, An. pseudojamesii, Aedes stevensoni, Ae. edwardsi, Ae. vittatus, Culex barraudi, Cx. fatigan...