Pahriya Ashrap

Pahriya Ashrap
University of Michigan | U-M · School of Public Health

Master of Science

About

28
Publications
1,830
Reads
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360
Citations
Citations since 2016
28 Research Items
360 Citations
2016201720182019202020212022020406080100120
2016201720182019202020212022020406080100120
2016201720182019202020212022020406080100120
2016201720182019202020212022020406080100120
Introduction
PhD student University of Michigan School of Public Health studying the impact of environmental exposures on maternal and children's health
Additional affiliations
September 2017 - present
University of Michigan
Position
  • Graduate Research Assisstant
Description
  • Reproductive Epidemiology
July 2017 - August 2017
Qarluq Media Technology
Position
  • Lecturer
Description
  • Gave lectures on the application of Computer Science and Biostatistics in Public Health
May 2017 - July 2017
Ijtihat Education
Position
  • Instructor
Description
  • Taught Chinese high school mathematics on Ijtihat online education: http://ijtihat.com/
Education
August 2017 - May 2021
University of Michigan
Field of study
  • Environmental Health Sciences
August 2015 - May 2017
Harvard University
Field of study
  • Environmental Health
August 2011 - July 2015
Peking University
Field of study
  • Environmental Science

Publications

Publications (28)
Article
Full-text available
Background Phthalates have been reported to alter circulating lipid concentrations in animals, and investigation of these associations in humans will provide greater understanding of potential mechanisms for health outcomes. Objective To explore associations between phthalate metabolite biomarkers and lipidomic profiles among pregnant women (n = 9...
Article
Full-text available
Background/Aim: The association between heavy metal exposure and adverse birth outcomes is well-established. However, there is a paucity of research identifying biomarker profiles that may improve the early detection of heavy metal-induced adverse birth outcomes. Because lipids are abundant in our body and associated with important signaling pathwa...
Article
Personal care products (PCPs) refer to a wide variety of items commonly characterized as health or beauty products. PCPs contain a number of ingredients, often including a wide range of endocrine disrupting chemicals such as phthalates and parabens. The present study examines the association between self-reported PCP use and prenatal sex-steroids a...
Preprint
Full-text available
Background: Phthalates have been reported to alter circulating lipid concentrations in animals, and investigation of these associations in humans will provide greater understanding of potential mechanisms for health outcomes. Objective: to explore associations between phthalate metabolite biomarkers and lipidomic profiles among pregnant women (n =...
Article
Background: Studies on the health effects of metal mixtures typically utilize biomarkers measured in a single biological medium, such as blood or urine. However, the ability to evaluate mixture effects are limited by the uncertainty whether a unified medium can fully capture exposure for each metal. Therefore, it is important to compare and assess...
Article
Exposures to phthalate compounds have been linked to adverse birth outcomes, potentially through oxidative stress mechanisms. We explored associations between mixtures of biomarkers of phthalate and phthalate replacement metabolites and oxidative stress using lipid peroxidation biomarker 8-iso-prostaglandin-F2α (8-iso-PGF2α). As 8-iso-PGF2α can be...
Article
Full-text available
Lipidome-wide metabolites may be useful biomarkers of pregnancy outcomes. We sought to characterize maternal lipidomic signatures associated with preterm birth and neonatal anthropometric parameters. Plasma samples were collected 24–28 weeks gestation, and lipidomic profiling was quantified using high-performance liquid chromatography tandem mass s...
Article
Full-text available
Background Metal exposure and psychosocial stress in pregnancy have each been associated with adverse birth outcomes, including preterm birth and low birth weight, but no study has examined the potential interaction between them. Objectives We examined the modifying effect of psychosocial stress on the association between metals and birth outcomes...
Article
Full-text available
Background Metal(loid)s have been associated to adverse birth outcomes in experimental and epidemiological studies, but the underlying mechanism(s) are not well understood. Endocrine disruption may be a mechanism by which the metal(loid)s impact birth outcomes. Methods Pregnant women were recruited through the Puerto Rico Testsite for Exploring Co...
Article
Full-text available
Metal exposure has been associated with a wide range of adverse birth outcomes and oxidative stress is a leading hypothesis of the mechanism of action of metal toxicity. We assessed the relationship between maternal exposure to essential and non-essential metals and metalloids in pregnancy and oxidative stress markers, and sought to identify window...
Preprint
Full-text available
Background: Lipidome-wide metabolites may be useful biomarkers of pregnancy outcomes. We sought to characterize maternal lipidomic signatures associated with preterm birth and neonatal anthropometric parameters. Methods: Plasma samples were collected 24-28 weeks gestation, and lipidomic profiling was quantified using high-performance liquid chromat...
Preprint
Full-text available
Metal exposure has been associated with a wide range of adverse birth outcomes and oxidative stress is a leading hypothesis of the mechanism of action of metal toxicity. We assessed the relationship between maternal exposure to essential and non-essential metals and metalloids in pregnancy and oxidative stress markers, and sought to identify window...
Article
Full-text available
Background Endocrine disrupting chemicals (EDCs) such as metals have been reported to alter circulating reproductive hormone concentrations and pubertal development in animals. However, the relationship has rarely been investigated among humans, with the exception of heavy metals, such as Pb and Cd. Our aim was to investigate measures of in utero a...
Preprint
Full-text available
Background Endocrine disrupting chemicals (EDCs) such as metals have been reported to alter circulating reproductive hormone concentrations and pubertal development in animals. However, the relationship has rarely been investigated among humans, with the exception of heavy metals, such as Pb and Cd. Our aim was to investigate measures of in utero a...
Preprint
Full-text available
Background: Endocrine disrupting chemicals (EDCs) such as metals have been reported to alter circulating reproductive hormone concentrations and pubertal development in animals. However, the relationship has rarely been investigated among humans, with the exception of heavy metals, such as Pb and Cd. Our aim was to investigate measures of in utero...
Preprint
Full-text available
Background: Endocrine disrupting chemicals (EDCs) such as metals have been reported to alter circulating reproductive hormone concentrations and pubertal development in animals. However, the relationship has rarely been investigated among humans, with the exception of heavy metals, such as Pb and Cd. Our aim was to investigate measures of in utero...
Preprint
Full-text available
Background: Endocrine disrupting chemicals (EDCs) such as metals have been reported to alter circulating reproductive hormone concentrations and pubertal development in animals. However, the relationship has rarely been investigated among humans, with the exception of heavy metals, such as Pb and Cd. Our aim was to investigate measures of in utero...
Article
Full-text available
Background In previous studies, exposures to heavy metals such as Pb and Cd have been associated with adverse birth outcomes; however, knowledge on effects at low levels of exposure and of other elements remain limited. Method We examined individual and mixture effects of metals and metalloids on birth outcomes among 812 pregnant women in the Puer...
Article
Given the potential adverse health effects related to toxic trace metal exposure and insufficient or excessive levels of essential trace metals in pregnant women and their fetuses, the present study characterizes biomarkers of metal and metalloid exposure at repeated time points during pregnancy among women in Puerto Rico. We recruited 1040 pregnan...
Article
Full-text available
Background: As a result of evidence suggesting phthalate toxicity, their use has decreased in recent years. However, new phthalates and non-phthalate replacements have emerged in their place, with unknown potential impacts on health. Methods: We measured 15 phthalate, two di(2-ethylhexyl)terephthalate (DEHTP), and two di(isononyl)cyclohexane-1,2...
Article
Full-text available
Background: Understanding important sources and pathways of exposure to common chemicals known or suspected to impact human health is critical to eliminate or reduce the exposure. This is particularly important in areas such as Puerto Rico, where residents have higher exposures to numerous chemicals, as well as higher rates of many adverse health...
Article
Significance Organisms are exposed to a wide range of xenobiotics in the environment. Generally, metabolism of individual xenobiotics to water-soluble compounds is a primary defense against these compounds. In this study, we discovered that phenolic xenobiotics undergo a metabolic pathway to form lipophilic ester compounds, and the pathway occurred...

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