Owolabi Joshua

Philadelphia College of Osteopathic Medicine | PCOM · Biomedical Sciences

The Anatomy Acts made provisions for handling cadaveric bodies for the purpose of Anatomical examinations and education such as dissection and prosections. The tissue act was developed from such documents in some countries to meet the need for handling of human tissue and remains 1,2. Some countries have modern laws to specifically address the ma...

ABSTRACT The juvenile is vulnerable to psychoactive agents and environmental influences. Caffeine, nicotine, and 3,4-Methylenedioxymethamphetamine (MDMA) could influence the developing brain with potential consequences on mental attributes including memory, cognition, behaviour, and learning. This re�search studied the structural and functional...

Abstract Background: The Anatomage Table is a modern technology that is used to enhance the teaching of human anatomy and related basic medical sciences to medical and allied health students. Its use is gaining popularity. This study considered anatomy teachers' perception and acceptance of the Anatomage Table technology and digital teaching materi...

Joshua Owolabi1,2 1Department of Anatomy, University of Global Health Equity, Butaro, Rwanda; 2Department of Anatomy, Babcock University, Ilishan-Remo, NigeriaCorrespondence: Joshua Owolabi, Department of Anatomy, University of Global Health Equity, Butaro, Rwanda, Tel +234-80-6488-4305, Email jowolabi@ughe.orgAbstract: Drug epidemiology basically...

Objective This cross-sectional study aimed to assess the prevalence and awareness of drug and substance abuse among undergraduates in four southwestern universities in Nigeria. Methods The sample of 400 students included 100 male and female students in the 15- to 29-year age range from each of the four selected universities in southwest Nigeria be...

Background Despite widespread concerns about its possible side effects, notably on the prefrontal cortex (PFC), which mediates cognitive processes, the use of Cannabis sativa as a medicinal and recreational drug is expanding exponentially. This study evaluated possible behavioral alterations, neurotransmitter levels, histological, and immunohistoch...

Anatomy, a foremost basic medical science (BMS) has evolved in content and context, while remaining the most fundamental BMS subject. Stakeholders have continually made efforts especially in recent time to achieve an evolution of this subject. The primary aim of this work was to study the perceptions and experiences of Anatomists towards contributi...

The juvenile is vulnerable to psychoactive agents and environmental influences. Caffeine, nicotine, and 3,4-Methylenedioxymethamphetamine (MDMA) could influence the developing brain with potential consequences on mental attributes including memory, cognition, behaviour, and learning. This research studied the structural and functional changes attri...

The developing brain at the adolescent stage is prone to the effects of various psychoactive agents and environmental influences. Caffeine, nicotine and MDMA influences on the developing brain and the possible consequences of such on fundamental mental attributes that determine brain health primarily including memory, cognition, behavior and learni...

Background: This article presents a qualitative study of African anatomists and anatomy teachers on the Anatomage Table-a modern medical education technology and innovation, as an indicator of African anatomy medical and anatomy educators' acceptance of EdTech. The Anatomage Table is used for digital dissection, prosection, functional anatomy demo...

Educational technology and innovations as well as creative approaches to teaching, learning, and training have become increasingly integral to the delivery of medical education. Arguably, the COVID-19-related challenges of the years 2020-2022 would mark a watershed point in terms of the integration of digital technology and innovations into educati...

Background Anatomy education in this context refers to the training of anatomists particularly in the university or college setting with an emphasis on equipping them with skills to be biomedical researchers and scientists, educators, and providers of applied or allied health services. There has been a recurring call to carefully evaluate and scrut...

Anatomy in the context of medical or health science often requires dissection. Anatomical dissection is the purposeful and procedural exploration of the human tissues and organs by physically cutting through defined body planes, regions, and organs to access, define and explore the structures in a manner that facilitates learning. Anatomical dissec...

We aimed to determine whether a Case-Based Collaborative Learning (CBCL) curriculum, developed from the clinical experience of U.S.-based clinicians in collaboration with Rwandan medical faculty, is acceptable, feasible to implement , and effective as a virtual educational tool for medical students in a resource limited , global health setting. In...

Introduction: Frontal lobe Epilepsy is a neurological disorder characterized by brief, recurrent seizures which arise from the frontal lobes of the brain. Bryophyllum pinnatum, is a natural herb which has been known for its anticonvulsant potential in experimental animals. The ketogenic diet is a form of treatment for epilepsy in children created d...

This article presents the experience and reflections of medical educators following the introduction of the Anatomage table, an educational technology or EdTech to our medical school for the purpose of supporting the teaching of anatomy and related basic medical sciences to medical school. It was considered a critical need by the stakeholders inclu...

The ASIC [adaptation, standardisation, integration and compliance] framework was developed to set the standard for the use of innovations and technologies in medical education. There is a need to develop frameworks and reference guides for educational technologies [EdTechs] and innovations, noting that EdTechs are becoming increasingly important to...

Background Certain factors have affected medical education significantly most recently. One is the rapidly evolving landscape of medical education, globally. This has created a spectrum of impacts on not just how medical education is being delivered but, on the definitions, and characterizations of competencies required of trained medical practitio...

Joshua Owolabi Department of Anatomy, Division of Basic Medical Sciences, School of Medicine, University of Global Health Equity, Butaro, Burera, RwandaCorrespondence: Joshua OwolabiDepartment of Anatomy, Division of Basic Medical Sciences, School of Medicine, University of Global Health Equity, Butaro, Burera, RwandaTel +250 781164365Email jowolab...

Stakeholders in the field of medical education globally would generally agree that sustaining medical education through the dark times of the covid-19 pandemic is worth celebrating. In the midst of the difficulties that were created generally by the covid-19 pandemic, sustaining medical education required persistence, strategy, courageous leadershi...

Background : The stimulant, empathogenic, euphoric, and hallucinogenic properties of 3,4-methylenedioxymethamphetamine (MDMA), also known as 'Ecstasy,' make it a popular drug among teenagers. These effects are thought to be caused by significant increases in dopamine, serotonin, and glutamate neurotransmission. However, little is known about Garcin...

Background The study was done to establish the neurotoxic effect of intracerebroventricular streptozotocin (ICV STZ)-induced brain insulin resistance, and also considered Zingiber officinale (Z. officinale) mechanism of action in ameliorating behavioural, molecular and histopathological changes associated with ICV STZ-induced brain insulin resistan...

The teaching of Anatomy has to evolve in line with modern trends in training medical doctors and health professionals in general. High fidelity simulation [HFS] is a modern way to train doctors on body functions as well as clinical and surgical procedures. The ability of the HFS to mimic occurrences in living conditions and their aberrations as as...

Introduction Radiofrequency radiation (RFR) is a form of non-ionising radiation that is used or emitted by a number of technologies and innovative devices including mobile phones and computers and gadgets. Exposure to RFR has been reported to have certain negative effects on human health. It is clear that quality and reliable data will be required...

Abstarct Background 3,4-methylenedioxymethamphetamine (MDMA) is a psychoactive drug that teenagers and young adults habitually abuse for pleasurable sensations and can cause neurological disorders. Aim: This research focuses on investigating the attenuating potential of Ginkgo biloba (G. biloba) aqueous extract, following MDMA-induced neurodegener...

Chronic stress if not manage properly results to major depression disorder which has profound impact on individual's life quality and deeply related to suicide death worldwide. This serious mental disorder is closely linked to the hippocampus due to it functionality in the regulation of cortisol production. Abelmoschus Esculentus (A. Esculentus) po...

Adapting, integrating, and standardizing the use of the Anatomage A presentation on how to use the Anatomage and other innovative educational technologies in the teaching of Anatomy and Medical Sciences.

Caffeine is globally consumed as a stimulant in beverages. It is also ingested in purified forms as power and tablets. Concerns have been raised about the potential consequences of intrauterine and early life caffeine exposure on brain health. This study modeled caffeine exposure during pregnancy and early postanal life until puberty, and the poten...

The prefrontal cortex (PFC), mediating executive brain functions is impaired in epilepsy. Allium sativum (AS) anti-seizure potential on the PFC of experimentally-induced epilepsy was investigated. Forty-eight male Wistar rats (200-250g) were randomized into six groups. Control (2mL/kg distilled water); AS only (100mg/kg); LiCl+PC (lithium chloride,...

The implications of the use of psychoactive substances, that are usually abused on the retina are yet to be adequately explored. The retina is neural in nature. Most investigations on psychoactive agents have only studied their effects on the brain and behaviour. The mechanisms employed by these agents in producing their effects on the brain sugges...

Background Early signs of neurodegenerative events of Alzheimer’s disease manifest within the hippocampus and presents as cognitive and memory impairment. Aluminium-chloride (AlCl3), a neurotoxicant interferes with the structure and functions of the hippocampus as well as its neurogenesis, thereby causing cognitive and memory impairment. Buchholzia...

Background: The research was designed to model the exposure to radiofrequency radiation (RFR) by habitual users of RFR-enabled devices and to observe possible aberrations in tissues that are attributable to exposures. The RFR exposure regimen modelled cases of continuous, and intermittent exposures in human conditions, using Wistar rats. The primar...

Background: The research was designed to model animals which mimic the exposure to the radiofrequency radiation [RFR] by habitual users of RFR-enabled devices and to observe possible aberrations in behaviours that are attributable to exposures. The research was designed to model cases of continuous, and intermittent exposures in human conditions, u...

Background: Aluminum chloride (AlCl3 ) present in many manufactured consumable is considered as a toxic element. Aim: Our study evaluates the toxic effects induced by AlCl3 on the testes as well as the therapeutic tendency of Quercetin (QUE) agent as an antioxidant. Setting and design: In the department of Anatomy of Medical School. Methods a...

This article is a descriptive and reflective piece on the strategic adaptations that facilitated and enabled the teaching of anatomy and related basic medical sciences to medical students in an African medical school that never shut down during the COVID-19 induced lockdown of the year 2020. The article considers the roles of educational technology...

The Brain Awareness Week is an annual program that is supported by the Dana Foundation to promote brain and mental health globally, and to create awareness. Stakeholders in the field of Neuroscience and mental health including researchers, clinicians, educators, science communicators, policy advocates and journalists are encouraged to share informa...

Introduction: Technological devices have become a very important part of our everyday life. These electronic devices create an artificial electromagnetic field (EMF) and emit radiofrequency radiations (RFR) which have been reported to have deleterious effects on various tissues in living organisms. Fish oil is a rich source of the n-3 (also known a...

Aim/Purpose: This article-a perspective, is an attempt to critically review the African scenario with respect to doctoral supervision for Basic Medical Sciences and proffer potential solutions in the form of a supervisory model. Background: There is a need to develop supervisory models for emerging PhDs in Basic Medical Sciences [BMS] in Africa. Th...

Caffeine is globally consumed as a stimulant in beverage drinks; it is also ingested in purified forms as power and tablets. Concerns have been raised about the potential consequences of intrauterine and early life caffeine exposure on brain health. This study modeled caffeine exposure during pregnancy and early postanal life until puberty, and the...

Background Garcinia kola (GK) has been experimentally tested for its potential usefulness against oxidative stress-related disorders in a number of body tissues, as well as a number of pathogenic and parasitic diseases. Studies investigating GK extracts’ usefulness in combating nervous tissue toxicity, neuroinflammatory disorders, and neuronal dege...

Background: Garcinia kola (GK) has been experimentally tested for its potential usefulness against oxidative stress-related disorders in a number of body tissues, as well as a number of pathogenic and parasitic diseases. Studies investigating GK extracts' usefulness in combating nervous tissue toxicity, neuroinflammatory disorders, and neuronal deg...

Neuroepidemiology is an important field that deserves critical attention globally and more specifically on the African continent. The African continent currently has less than adequate and reliable data on mental health generally or neurological disorders. Only few prevalence and incidence studies’ reports are available. Africa is affected by diver...

It is very important to address the need to adapt the existing structure to meet the demands of the emergency situation that has been placed on tertiary institutions globally and with specific emphasis on the African institutions. In the face of the emergency situations such as the one that has been created by the global pandemic covid-19; it is im...

Background: 3, 4-methylenedioxymethamphetamine (MDMA) causes neurological disorders. Garcinia kola (GK) has neuroprotective property. We investigated the neuroprotective roles of GK on MDMA-induced cerebellar damage. Method: Sixty male Wistar rats (120 - 160g), 5 months old were grouped into six (n =10). Rats were fed with normal chow and water ad...

Background: Repeated and regimented treatment with reserpine causes depression-like condition characterized by persistent mood disorder, feelings of severe despondency and dejection, thus altering the hippocampal morphology. Our study compared a well-known antidepressant (fluoxetine), with the potential of Zingiber officinale to ameliorate reserpi...

https://youtu.be/4kzw-D4qeQQ The article addresses how best to virtualise the school through strategic adaptations and changes. It addresses key factors including infrastructure, pedagogy, resources, assessment, quality assurance, student support system, technology, culture and best practices.

Recent findings show conflicting evidences of both beneficial and deleterious effects of inducible nitric oxide synthase (iNOS). Ascorbic acid (ACA) is a source of antioxidant. This study seeks to examine the role of iNOS in acetaminophen (APAP)-induced liver damage following treatment with ACA. Twenty (20) female rats (150-200g) were used for the...

Anatomy Education

The COVID-19 pandemic has affected health globally in a manner that this generation has never witnessed. The initial measures to mitigate these effects were focused on health interventions and remedies; rightly so. These had included public health measures including the lockdown, the test-and-contact-tracing and the social or physical distancing me...

The COVID-19 pandemic has affected health globally in a manner that this generation has never witnessed. The initial measures to mitigate these effects were focused on health interventions and remedies; rightly so. These had included public health measures including the lockdown, the test-and-contact-tracing and the social or physical distancing me...

This study investigated the effects of Parkia clappertoniana (PC) on the hippocampal structure and functions in Lithium Chloride-Pilocarpine-induced Epilepsy in Wistar rat Model. A total of 36 adult male Wistar rats were used for this study and divided into groups A to F, group A (Control), B (200mg/kg of PC), C (127mg/kg of Lithium chloride + 30mg...

The Covid-19 pandemic has affected health globally in a manner that this generation has never witnessed. The initial measures to mitigate these effects were focused on health interventions and remedies; rightly so. These had included public health measures including the lockdown, the test-and-contact-tracing and the social or physical distancing me...

Background The University of Global Health Equity (UGHE) is a new medical school in Rwanda that aims to train new physicians with competencies in global health delivery for Africa. As part of an effort to deliver high-quality, preclinical medical education, UGHE has implemented a low-cost, modular digital curricular platform called ScholarRx Bricks...

Introduction: Anatomy is currently a basic medical science bachelor program in Nigerian universities. The roles of anatomists in the Nigeria health, education and other relevant sectors are vaguely defined. Career prospects have been perceived to be very limited. Materials and methods: This study was a total population survey of all Nigerian pri...

Introduction: Skin bleaching is the act of using steroid- and chemical-containing products to lighten the skin. Hydroquinone and kojic acid are often used in skin bleaching creams. Hydroquinone was suspected to be harmful. This study investigated the effects of kojic acid and hydroquinone on the skin of adult female Wistar rats and the potential u...

Background The University of Global Health Equity (UGHE) is a new medical school in Rwanda that aims to train new physicians with competencies in global health delivery for Africa. As part of an effort to deliver high-quality, preclinical medical education, UGHE has implemented a low-cost, modular digital curricular platform called ScholarRx Bricks...

Cadmium is a toxic metal, an environmental contaminant and a multi-organ poison which has been implicated in the derangement of a number of biological and molecular systems. Exposure to cadmium is a serious global health threat particularly in developing countries and pregnant women are at great risk, This is because they have increased gastrointes...

Background: Alarming population increase with fewer resources in this century is undisputable especially in under-developed countries. Hence, the need for efficient and affordable birth control which majority don’t have access to, unfortunately. Aim: This study investigated the paradoxical anti-fertility effect of amlodipine in Wistar rats with a v...

Plastination is a modern method of preservation of biological specimens, including human cadavers. This study elucidated how temperature might affect plastination, noting that there is sparse scientific literature on this technique, especially from Africa. It is also relevant to the feasibility of adapting and adopting the technique as a feasible a...

Comparative Study of Forced Impregnation Temperatures Variation on the outcome of Brain Plastination. SONA 2019 Abstract

Caffeine nicotine and MDMA effects on retinal morphology and rhodopsin expression suggest potential functional consequences. SONA POSTER

Transcranial direct current stimulation (tDCS) is capable of modulating brain activity significantly and it has emerged as a promising treatment for schizophrenia and pain, and also to inhibit cravings. However, there is a rapid increase on the use of this neuro-stimulation method to enhance cognitive ability in healthy people. The present study in...