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18
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Introduction
Outi Kaarre currently works at the Niuvanniemi Hospital. Outi does research in Adolescent Psychiatry. Their current project is 'Adolescents and Alcohol Study.'
Current institution
Publications
Publications (18)
Adolescents’ health behavior is promoted by their social relationships, and social isolation may affect their health and use of health care services. No previous studies have examined the quality of social relationships and health care service use from adolescence to young adulthood. We investigated the associations between the quality of the socia...
Background
Adolescence is a particularly vulnerable stage of development in terms of the deleterious effects of alcohol. Both lower gray matter (GM) volume and greater GABAergic activity have been associated with chronic alcohol consumption during adolescence. However, the association between these measures has not been investigated.
Methods
In th...
Background:
Alexithymia has been related to adult health care use. We investigated the association between alexithymia and the utilization of primary health care services by adolescents and young adults.
Methods:
The participants (n = 751, aged 13-18 years) in this 5-year follow-up study were assessed with the 20-item Toronto Alexithymia Scale (...
Background:
The aims of this study were to investigate the stability of alexithymia from adolescence to young adulthood, as well as the association between alexithymia, peer relationships, and symptoms of depression and dissociation.
Methods:
The participants (n = 755, aged 13-18 years) were assessed with self-rated questionnaires and the 20-ite...
Excessive alcohol use results in cerebellar damage in adults, but there has been less research on how alcohol use during adolescence affects the cerebellum. In this study, we observed that heavy drinking from adolescence to young adulthood was associated with altered volumes of cerebellar lobules. The study included two groups consisting of 33 heav...
Life satisfaction is known to be associated with several social and mental adversities. We examined whether social activities and relationships in adolescence are related to life satisfaction in young adulthood. The psychosocial background characteristics of the study subjects (n = 787, aged 13–18 years) were recorded by using self-rated questionna...
Alcohol-related white matter (WM) microstructural changes have not been fully elucidated in adolescents. We aimed to investigate influences of subclinical alcohol use during adolescence on WM microstructure and to characterize those with serum metabolic alterations. 35 moderate-to-heavy drinkers (15 males, 20 females) and 27 controls (12 males, 15...
Purpose: Transcranial magnetic stimulation–induced motor responses have been considered to mainly reflect the electrophysiological characteristics of the central motor system. However, certain motor phenomena, such as the magnitude of repetition suppression measured with motor evoked potentials (MEPs), could also in part be influenced by metabolic...
Our aim was to analyze metabolite profile changes in serum associated with moderate-to-heavy consumption of alcohol in young adults and to evaluate whether these changes are connected to reduced brain gray matter volumes. These study population consisted of young adults with a 10-year history of moderate-to-heavy alcohol consumption (n = 35) and li...
The most thoroughly studied transcranial magnetic stimulation (TMS)-evoked electroencephalogram (EEG) potential (TEP), N100, is often defined as a measure of cortical inhibition.
We explored the association of the N100 amplitude with attention in 51 young healthy adults. Navigated TMS with simultaneous EEG registering was applied over the left pri...
Heavy alcohol use has been associated with reduced brain grey matter volume as well as alterations in the metabolic processes in the body. Here our aim was to analyze what metabolite profile changes in serum are associated with heavy use of alcohol in young adults as well as to evaluate if these changes are associated with reduced brain grey matter...
Long-term alcohol use affects cognitive and neurophysiological functioning as well as structural brain development. Combining simultaneous electroencephalogram (EEG) recording with transcranial magnetic stimulation (TMS) enables direct, in vivo exploration of cortical excitability and assessment of effective and functional connectivity. In the cent...
Background: Despite a large body of evidence of the negative effects of alcohol on cognitive functioning in adults, its effects in adolescence are still unclear. In previous studies, binge drinking in adolescence has been associated with poorer neurocognitive performance with regards attention, working memory, spatial functioning, verbal and visual...