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Publications
Publications (28)
In Burkina Faso, the health system is characterized by systemic insufficient and antiquated health-care infrastructures. Consequently, few health-care establishments have the required resources to diagnose and manage patients with COVID-19, and fewer still have intensive care facilities for severely ill patients with COVID. Furthermore, there is a...
Background
This study aimed to estimate the anti‐SARS‐CoV‐2 antibody seroprevalence in the general population of Bobo‐Dioulasso and Ouagadougou (Burkina Faso).
Methods
We collected from March to April 2021 blood samples from randomly selected residents in both main cities based on the World Health Organization (WHO) sero‐epidemiological investigat...
Abstract Background Early data on COVID-19 (based primarily on PCR testing) indicated a low burden in Sub-Saharan Africa. To better understand this, this study aimed to estimate the incidence rate and identify predictors of SARS-CoV-2 seroconversion in the two largest cities of Burkina Faso. This study is part of the EmulCOVID-19 project (ANRS-COV1...
Purpose
Little is known about whether baseline health-related quality of life (HRQoL) scores also could predict occurrence radiotherapy-related toxicities, which we aim to assess in this study.
Methods
This study analyzed data from 200 patients enrolled in randomized study investigating the utility of HRQoL. HRQOL was assessed at baseline and duri...
Background: Advances in screening and treatment have led to increase in breast cancer (BC) survival in recent years but prognoses for metastatic BC remain poor with poorer outcomes as health-related quality of life (HRQOL). Treatment as bevacizumab and paclitaxel for metastatic BC, although that can increase time to progression of disease, often ca...
Background Obesity has previously been correlated with poorer survival in both early and metastatic breast cancer. Adipose tissues release proangiogenic factors such as Insulin-like Growth Factor and Vascular Endothelial Growth Factor that may ultimately promote tumor growth. CTscan can be used to measure the visceral fat area (VFA) and the subcuta...
Background: In patients with metastatic breast cancer (mBC), Circulating Tumor Cells (CTC) counts have a strong prognostic impact on progression free survival (PFS) and overall survival (OS). Changes 4 weeks after the start of a new line of therapy, inform on treatment efficacy. Despite improvements in systemic treatment, metastatic BC remains main...
Purpose
Long-term effects of being the primary caregiver of an older patient with cancer are not known. This study aimed to assess health-related quality of life (HRQoL) in primary caregivers of patients aged 70 and older with cancer, 5 years after initial treatment. Secondly, to compare the HRQoL between former primary caregivers whose caregiving...
BackgroundHER2-positive (HER2 +) invasive lobular breast cancer (ILC) is rare and poorly characterised. In particular, patient outcomes compared to those associated with HER2 + invasive ductal cancer (IDC) and HER2-negative (HER2 −) ILC, as well as the benefits of anti-HER2 therapy, are not well established.Methods
We analysed the data from the Côt...
La prise charge des patients en cancérologie vise à la fois à garantir au patient le meilleur traitement mais aussi une meilleure préservation de sa qualité de vie. Dans ce travail de thèse, nous avons cherché à mettre en évidence comment l’intégration des paramètres reportés par les patients comme la qualité de vie, dans la prise en charge, pourra...
Purpose/Objective(s)
aims to assess the association between baseline HRQOL and occurrence of major toxicities in patients with head and neck cancer (HNC).
Materials/Methods
The present study analyzed data from randomized study investigating the utility of HRQoL assessment. Patients with HNC treated by radiotherapy were included from May 2009 to Se...
État de la question
Bien qu'associée à la survenue de complications majeures, l'œsophagectomie constitue la principale option de traitement curatif pour les patients atteints d'un cancer de l'œsophage. Le but de cette étude était d’évaluer l'impact de la qualité de vie (QdV) initial sur la survenue des complications et de décès postopératoires chez...
Background
The aim of this study was to assess the impact of baseline health related quality of life (HRQOL) on the occurrence of postoperative complications and death in patients with resectable esophageal cancer.
Methods
Existing data from a prospective, multicenter, open label, randomized, controlled phase III trial comparing hybrid versus open...
During the past 15 years, in France, like in many European countries, the attention paid to patients at the end of their lives has continued to grow. But in the meantime, only a few researchers have managed to collect reliable data on End-of-Life Care and to implement scientific studies describing the reality of these situations. This difficulty is...
Background
The world has high hopes of vaccination against COVID-19 to protect the population, boost economies and return to normal life. Vaccination programmes are being rolled out in high income countries, but the pandemic continues to progress in many low-and middle-income countries (LMICs) despite implementation of strict hygiene measures. We a...
The impact of routine assessment of health-related quality of life (HRQoL) on satisfaction with care and the HRQoL of patients with head and neck cancer (HNC) treated with radiotherapy was assessed. Patients with HNC were randomly assigned to two arms, with stratification on sex, cancer localization, and stage of the disease. In the intervention ar...
Introduction
La plupart des données sur l’efficacité de l’hormonothérapie proviennent d’essais cliniques randomisés. Peu ou moins de données existent sur l’efficacité de l’hormonothérapie en vie réelle et sa prescription au cours du temps. Cette étude avait pour objectif d’identifier les facteurs pronostiques de la survie chez les femmes atteintes...
Introduction
Au cours de ces dernières années, l’évaluation de la qualité de vie liée à la santé est devenue un objectif majeur dans la prise en charge des patients en cancérologie. La qualité de vie comme facteur pronostique a été étudiée dans plusieurs études. Toutefois, dans ces différentes études, le rôle pronostique de la qualité de vie semble...
Purpose
To identify prognostic factors of invasive–disease free survival (iDFS) in women with non-metastatic hormone receptor positive (HR+) breast cancer (BC) in daily routine practice.
Methods
We performed a retrospective study using data from the Côte d’Or breast and gynecological cancer registry in France. All women diagnosed with primary inva...
Background: The world has high hopes of vaccination against COVID-19 to protect the population, boost economies and return to normal life. Vaccination programmes are being rolled out in high income countries, but the pandemic continues to rage in many low-income countries (LICs) despite implementation of strict hygiene measures. We aim to present a...
According to international guidelines, endocrine therapy (ET) is the preferred option for hormone receptor-positive (HR+) HER2-negative (HER2−) metastatic breast cancer. In spite of clear recommendations, these are not strictly followed in daily practice. The objectives of this study were to investigate the effect of the first anti-metastatic treat...
Objective
To describe socio‐economic and professional outcomes in long‐term survivors of cervical, endometrial or ovarian cancer, including return to work and problems related to obtaining loans and insurance.
Methods
Women with cervical, endometrial or ovarian cancers diagnosed from 2006 to 2013 were selected through the French gynaecological can...
Background: Nowadays, the assessment of health related quality of life (HRQOL) in women with breast cancer (BC) has become very important, with the improvement of their prognosis and the growing number of BC survivors. HRQOL is therefore a main endpoint in cancer therapeutic care and its improvement should be an important goal of BC treatment. The...
Background: The incidence of breast cancer (BC) increases with age. However, there appears to be a trend that elderly patients with BC receive less than the standard treatment compared to younger ones and this leads to poorer outcomes. The aim of this work was to assess whether chemotherapy has a differential impact on the health related quality of...
Background
The likelihood that health-related quality of life (HRQoL) could depend on factors other than clinical data increases with the duration of follow-up since diagnosis. The aim of this study was to identify determinants of long-term HRQoL in women with cervical, endometrial, and ovarian cancer. Secondary objectives were to describe their li...
Compared to the general population, HIV-infected patients are at higher risk of developing non-AIDS-defining cancers. Chronic HCV infection has also been associated with a higher risk than that of the general population of developing cancers other than hepatocarcinoma. Evaluation of the impact of HCV-related factors on non-AIDS-defining and non HCV...
Introduction
Le nombre de décès attribuables aux cancers non liés au VIH ou VHC a augmenté ces dernières années. L’objectif de cette étude était d’étudier les facteurs associés à la survenue de ces cancers dans une large cohorte nationale de patients co-infectés VIH/VHC.
Matériels et méthodes
Les patients co-infectés par le VIH et le VHC sans anté...
