Otobong Donald Akan

Akwa Ibom State University · Microbiology

The influence of cooking and dietary palm oil on the nutrient and anti-nutrient contents of cocoyam was investigated. Cocoyam is ranked third in importance, and has been found to be nutritionally superior to cassava and yam due to its easily digestible starch and high protein, vitamins and mineral contents. There are heath concerns over the anti-nu...

Ethanol and other congeners in alcoholic beverages and foods are known triggers of alcohol-induced headaches (AIHs). Recent studies implicate AIHs as an important underlying factor for neuroinflammation. Studies show the relationship between alcoholic beverages, AIH agents, neuroinflammation, and the pathway they elicit. However, studies elucidatin...

Gastrodia elata Bl. is traditional Chinese medicine used to alleviate fatigue, but its underlying mechanism is still unclear. This study explored the anti-fatigue mechanism of gastrodin by exercise-induced fatigue model and network pharmacology. This study found that gastrodin (200 mg/kg/day) had significant anti-fatigue effects in C57BL/6J mice ba...

Traditional fermented foods harbor microbes that transform raw food components, improving their nutritional, shelf life, organoleptic, and health-promoting characteristics. Fermented foods are an important conduit of contact between bioactive components that act like antigens and the human body system. Versatile microbes in traditional fermented fo...

The link between increasing global population, food demand, industrialization, and agricultural waste is strong. Decomposing by-products from food cycles can introduce harmful toxic heavy metals, active degrading microbes, and enzymes to the environment. Additionally, high greenhouse gas emissions from the decomposing wastes contribute to global ch...

Gastrodin is a traditional Chinese medicine and has been used to alleviate fatigue, but its underlying mechanism is still unclear. This study explored the anti-fatigue mechanism of gastrodin by exercise-induced fatigue model and network pharmacology. This study found that gastrodin (200 mg/(kg day)) has obvious anti-fatigue effect according to ener...

Sirtfood is a new concept food that compounds diets that can target sirtuins (SIRTs). SIRTs are nicotinamide adenine dinucleotide (NAD+)-dependent deacylases and ADP-ribosyltransferases (enzymes). SIRTs are mediators of calorie restriction (CR) and their activation can achieve some effects similar to CR. SIRTs play essential roles in ameliorating o...

Hyperlipidemia is intricately associated with the dysregulation of gut microbiota and host metabolomes. This study explored the antihyperlipidemic function of oryzanol and investigated whether the function of oryzanol affected the gut microbiome and its related metabolites. Hamsters were fed a standard diet (Control) and a high fat and cholesterol...

This work reviews microplastic's impact on agroecosystem components and possible effects on the food chain. Microplastics are sized < 5 µm, made up of diverse chemical constituents, and come from several sources. The agroecosystems reportedly receive an estimated 1.15 to 2.41 million tonnes of plastic wastes annually. Micro-plastic factors like inc...

Mol. Nutr. Food Res. 2022, 66, 202100732 DOI: 10.1002/mnfr.202100732 AMPK pathway plays vital role in the energy metabolism. Recent investigations indicate that AMPK is closely related with carcinogenesis. Polyphenols can target AMPK to promote apoptosis and cell cycle arrest of cancer cells. Besides interfering with classical carcinogenesis pathwa...

The interest in proteomic studies of fermented food is increasing; the role of proteins derived from fermentation extends beyond preservation, they also improve the organoleptic, anti-pathogenic, anti-cancer, anti-obesogenic properties, and other health conferring properties of fermented food. Traditional fermentation processes are still in use in...

Cancer is a serious public health problem in the world and a major disease affecting human health. Dietary polyphenols have shown good potential in the treatment of various cancers. It is worth noting that cancer cells usually exhibit metabolic abnormalities of high glucose intake and inefficient utilization. AMPK is the key molecule in the regulat...

The Poster contains illustrations and links between disease outbreaks and enabling factors that sustain their infection rates. One major disease determinant and driver is finance: level of health investment speaks volume on the health status and productivity of a country (and her citizens). It is more economical to control disease determinants and...

Antibiotic resistant bacteria pathogens remain the leading cause of shellfish borne diseases and a major health threat to humans worldwide. The objectives of this study were to isolate, identify, and determine the antibiotic resistance patterns of Gram-negative bacteria from shellfish. We analyzed a total of 540 shellfish (117 clams, 88 oysters, an...

This paper presents a review of synthetic polymer (notably plastic) wastes profiles in Africa, their current management status, and better options. Data revealed that of the approximated 86.14 million metric tonnes and 31.5 million metric tonnes of primary polymers and plastics, respectively, and an estimated 230 million metric tonnes of plastic co...

Bioactive substances derived from natural products are valued for effective health-related activities. As extremely important component of plants, animal cell membrane and microbes cytoderm, polysaccharides have been applied as medications, foods and cosmetics stemming from their prominent biological functions and minor side-effects. Recent studies...

Background:Multi drug resistant bacterial agents that contaminate seafood cause several diseases in humans and are widely documented as a global public health challenge. Methods: This study evaluated the microbiological and antimicrobial resistance genes profiles of bacterial Isolates from shellfish vended at Iko and Douglas Creeks of Cross River S...

Background: Multi drug resistant bacterial agents that contaminate seafood cause several diseases in humans and are widely documented as a global public health challenge. Methods: This study evaluated the microbiological and antimicrobial resistance genes profiles of bacterial Isolates from shellfish vended at Iko and Douglas Creeks of Cross River...

Obesity has many angles to its cause. Epidemiological works on diets and diet components show that obesity and other metabolic diseases are controlled to a large extent with proper diet and lifestyle. Most works with plant-based diets are noteworthy; they stimulate mechanisms in the host that proffer health, either through calorie restrictive pathw...

Aim: This study evaluated the Multi-drug resistance (MDR) pattern of Staphylococcus aureus from a paediatric ward and was conducted using standard clinical microbiological procedures. Location and Duration of Study: The study was carried out on infant samples collected from the Paediatric ward, General Hospital, Ikot-Ekpaw, Mkpat Enin LGA, Akwa-Ibo...

Aim: This study evaluated the Multi-drug resistance (MDR) pattern of Staphylococcus aureus from a paediatric ward and was conducted using standard clinical microbiological procedures. Location and Duration of Study: The study was carried out on infant samples collected from the Paediatric ward, General Hospital, Ikot-Ekpaw, Mkpat Enin LGA, Akwa-Ibo...

The quantitative analysis of total carotenoids in some vegetables consumed in Akwa Ibom State was evaluated using UV-Spectrophotometer and acetone as extraction solvent. Ten different vegetable samples i.e. Carrot (Daucus carota),purpleegg plant(Solanum melongena), green egg plant (Solanum melongena), tomato(Solanum lycopersicum), cucumber(Cucummis...

Aim: This study investigated the occurrence of multi-drug resistant (MDR) and Plasmid-Mediated Quinolone Resistant (PMQR) genes in Salmonella enterica isolated from shellfish in Iko Creek, Nigeria. Study Design: This is an experimental research that studied Salmonella enterica isolated from shellfish to determine its association with MDR and PMQR u...

It is a work done on an important enzyme, glucose isomerase, isolated from Achromobacter xylosoxidans mck-4

The microbial diversity and heavy metal concentration s of wood smoked fishes ( Clarias gariepinu s and Pseudotolithus elongatus ) from Edonwhii fishing settlement in Akwa Ibom State, Nigeria were investigated using standard microbiological protocols and analytical procedures, to ascertain the level of fish contamination. The study revealed v...

The problem that has been ravaging ethanol producing industries for decades now is the ability of industrial yeast isolates to withstand ethanol production stress conditions while giving out optimal ethanol yeast. Hence, there is need to constantly source for yeast isolates with these qualities. Yeast isolates obtained from aging palm-wine were inv...

Seasonal variation of heavy metal concentrations in crude oil polluted water around major tributaries in Ibeno, a coastal area, in Niger Delta. Nigeria was investigated using Atomic Absorption Spectrophotometer Unicam 939 model. The concentrations in mg L-1 of heavy metals in water during the dry season was in decreasing order of: Mn(2.80±0.93), V(...

The influence of bacterization of biostimulant (maize chaff) on hydrocarbon degradation of crude oil impacted soil was studied. The study revealed the presence of bacterial isolates with strong crude oil utilization potentials. Pseudomonas aeruginosa, and Bacillus subtilis were the strongest degraders, Micrococcus and Corynebacterium were moderate...

Introduction: Black eye pea (Vigna unguiculata), because of its preferred taste and nutritional value is one of the commonly eaten beans in Nigeria. Aim: The effect of processing techniques like soaking, dehulling and drying on microbial quality, nutritional and mineral composition of black-eyed bean was studied. Study Design: One cup of black-eyed...

A study of the rate of crude oil remediation in soils with the application of surfactants and hydrocarbonoclastic bacterial population was undertaken. Locally sourced particulate surfactants (wood and palm bunch ashes) were compared with synthetic surfactant, Tween 80, and found to be more microbial friendly and efficient in contaminant removal fro...

The efficiency of two surfactants; wood ash (a domestic/agricultural by-product) and Tween 80 (a chemically synthesized surfactant) was investigated during the bioremediation of crude oil contaminated soil. The soil samples were contaminated with crude oil at 5% and 10% levels and inoculated with hydrocarbonoclastic organisms. Microbial anaylsis of...