Oscar Mancera-Páez

Oscar Mancera-Páez
University of Texas Health Science Center at Houston · Department of Neurology

MD, Neurologist

About

16
Publications
3,285
Reads
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201
Citations
Citations since 2017
15 Research Items
198 Citations
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20172018201920202021202220230102030405060
Introduction
Oscar Mancera-Páez currently works at UT Health Science Center, Neurology Department at Houston

Publications

Publications (16)
Article
Full-text available
Introduction Alzheimer disease risk polymorphisms have been studied in patients with dementia, but have not yet been explored in mild cognitive impairment (MCI) in our population; nor have they been addressed in relation to cognitive variables, which can be predictive biomarkers of disease. Objective To evaluate cognitive performance and presence...
Article
Chronic inflammatory demyelinating polyneuropathy (CIDP) is an autoimmune disease characterized by neurological symptoms and signs of progressive weakness, paresthesias, and sensory dysfunction. Other symptoms include reduced or absent tendon reflexes, cranial nerve involvement, autonomic symptoms, ataxia, and neuropathic pain. Unlike other autoimm...
Article
Full-text available
Background: Biomarkers are essential for identification of individuals at high risk of mild cognitive impairment (MCI) for potential prevention of dementia. We investigated DNA methylation in the APOE gene and apolipoprotein E (ApoE) plasma levels as MCI biomarkers in Colombian subjects with MCI and controls. Methods: In total, 100 participants wer...
Preprint
Full-text available
Background: Biomarkers are essential for identification of individuals at high risk of mild cognitive impairment (MCI) for potential prevention of dementia. We investigated DNA methylation in the ApoE gene and plasmatic apolipoprotein E (ApoE) levels as MCI biomarkers in Colombian subjects with MCI and controls. Methods: 100 participants were inclu...
Article
Full-text available
DNA methylation and other epigenetic factors are important in the pathogenesis of late-onset Alzheimer’s disease (LOAD). Methylenetetrahydrofolate reductase (MTHFR) gene mutations occur in most elderly patients with memory loss. MTHFR is critical for production of S-adenosyl-l-methionine (SAM), the principal methyl donor. A common mutation (1364T/T...
Preprint
Full-text available
DNA methylation and other epigenetic factors are important in the pathogenesis of late-onset Alzheimer’s disease (LOAD). Methylenetetrahydrofolate reductase (MTHFR) gene mutations occur in most elderly patients with memory loss. MTHFR is critical for production of S-adenosyl-L-methionine (SAM), the principal methyl donor. A common mutation (1364T/T...
Article
We thank Yasri and Wiwanitkit for their comments on our review article of Zika virus (ZIKV) neurotropism [1,2]. They indicate that in their geographic region in South East Asia (Thailand) —a ZIKV endemic area— the concurrent immunoreactivity to ZIKV and other arboviruses is very common, particularly with dengue virus (DENV) and Chikungunya virus (C...
Article
Full-text available
Introduction: Alzheimer disease risk polymorphisms have been studied in patients with dementia, but have not yet been explored in mild cognitive impairment (MCI) in our population; nor have they been addressed in relation to cognitive variables, which can be predictive biomarkers of disease. Objective: To evaluate cognitive performance and prese...
Article
Full-text available
We review post-infectious and post-vaccination neurological syndromes involving peripheral and central nervous system (CNS) and report an illustrative case of simultaneous occurrence of Guillain-Barré syndrome (GBS), confirmed by nerve conduction velocities, plus MRI-demonstrated transverse myelitis (TM) and acute encephalitis [acute disseminated e...
Chapter
Full-text available
Neurologic diseases prevention by control of modifiable risk factors. Educational guideline.
Article
Full-text available
We review post-infectious and post-vaccination neurological syndromes involving peripheral and central nervous system (CNS) and report an illustrative case of simultaneous occurrence of Guillain-Barré syndrome (GBS), confirmed by nerve conduction velocities, plus MRI-demonstrated transverse myelitis (TM) and acute encephalitis [acute disseminated e...
Data
Supplementary file 1: cognitive assessment test (CATest) instrument English version. Supplementary file 2: cognitive assessment test (CATest) instrument Spanish version.
Article
Full-text available
Introduction Cognitive disorders are a clinical and research challenge; in particular, the mild cognitive disorder (MiCD) requires diagnostic suspicion and tools with adequate performance for its detection. The objective of this study was the validation of a short cognitive test (CATest) for the detection of MiCD in population of 50 years or more....
Poster
Objective: To share our experience with 4 cases of central demyelinating diseases (CDD) with infranuclear facial palsies either on initial presentation or as an acute CDD exacerbation. We will provide an insight on the pathogenesis and management of facial palsies based on clinico-imaging correlation. Background: Facial palsies in MS and NMOSD ar...
Article
Full-text available
Status epilepticus case series in Colombia
Article
Full-text available
Background: The objective of this study was to analyze the impact of a multidimensional infection control approach and the use of the International Nosocomial Infection Control Consortium (INICC) Surveillance Online System on central line-associated bloodstream infection (CLABSI) rates from June 2003-April 2010. Methods: We conducted a prospecti...

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