Oluwaseun Ruth Alara

Oluwaseun Ruth Alara
Universiti Malaysia Pahang | ump · Department of Chemical Engineering, College of Engineering

Doctor of Philosophy

About

85
Publications
86,116
Reads
How we measure 'reads'
A 'read' is counted each time someone views a publication summary (such as the title, abstract, and list of authors), clicks on a figure, or views or downloads the full-text. Learn more
1,278
Citations

Publications

Publications (85)
Article
Full-text available
The extracts from Vernonia amygdalina leaves dried using different modes of drying were examined for their antioxidant activities. The component identification was done for the extract that gave highest antioxidant activity using GC-MS analysis. Using DPPH, ABTS+• and H2O2 radical scavenging assays, the shade, the sun, oven at 40, 50, and 60 °C dri...
Article
Full-text available
Vernonia amygdalina leaves are mostly consumed in Asia and Africa, due to its potential as a good source of antioxidants. In this study, a two level factorial design was used for the recovery yield of extract, total phenolic content, total flavonoid content, and antioxidants from Vernonia amygdalina leaf. Microwave assisted extraction was employed...
Article
Diabetes mellitus is a metabolic disorder disease emanating from the inability of body's response to high glucose levels in the blood. However, the side-effects from consuming synthetic drugs have reduced the effectiveness, thus, the potential of purple fleabane (Vernonia cinerea) leaf was investigated using microwave-assisted extraction (MAE) in t...
Article
Full-text available
In this study, the effects of extraction solvents on the yield and total phenolic content of Vernonia amygdalina leaf were examined. The considered solvents were water, 20% v/v ethanol, 40% v/v ethanol, 60% v/v ethanol, 80% v/v ethanol, and 100% v/v ethanol using Soxhlet extraction technique. Highest extraction yield (19.45 ± 0.22% g/g) and total p...
Article
In this study, the microwave-assisted extraction (MAE) variables were optimized usinga face-centered central composite design of response surface methodology for optimalrecoveries of total flavonoid content (TFC) and antioxidant capacities (DPPH and ABTS) ofVernonia amygdalina leaf extract. The independent variables were irradiation time (5–15 min)...
Article
Using an effective technique in breaking emulsion is very important in the petroleum industry. This is due to the challenges of produced water facing the production of crude oil. The produced water that does accompany crude oil is linked to emulsion (water‐in‐oil, oil‐in‐water, and multiple emulsions) and can cause different environmental issues. I...
Article
Full-text available
The complicated nature of crude oil emulsions is part of the major setbacks associated with the postulation of methods for phase separation and demulsification in the oil industry. Despite the increasing efforts in generating efficient and dependable demulsification methods, the majority of emulsions cannot be shattered in reduced times. This revie...
Chapter
The free radicals are reactive molecules that emanate during oxidation; this can then stimulate a chain reaction that can cause cellular damage. A lot of studies had affirmed the implications of free radicals mostly the reactive oxygen species in generating over a hundred degenerative diseases in the human being; these include cancer, acquired immu...
Article
Carica papaya leaf is one of the considered agricultural waste; nevertheless, this leaf has been reported to contain diverse health benefits to humans. In as much as natural-based oils are of higher demands because of their aromatherapy property, this study focused on the extraction of oil from C. papaya leaf using microwave-assisted extraction (MA...
Article
Full-text available
Phenolic compounds are parts of secondary metabolites mostly found in plant species with enormous structural diversities. They can exist as glycosides or aglycones; matrix or free-bound compounds; and comprising mostly polymerized or monomer structures. Additionally, these compounds are not universally dispensed within plants with varied stability....
Article
Full-text available
Carica papaya is a well-known plant with diverse importance to human beings. The efficacy of microwave-assisted extraction (MAE) in the recovery of phenolic compounds from C. papaya leaf was investigated in this study. The MAE process variables were optimized using response surface method; at the optimized conditions, the embedded phenolic compound...
Chapter
Full-text available
In recent times, bioactive compounds from plant samples are extracted using a microwave extractor. This is because traditional methods of extraction are need of higher volume of solvents, degrade thermal-sensitive bioactive compounds, and consume much time of extraction. Hence, this chapter unveils the importance of the microwave-assisted extractio...
Article
Lubricating oils are made from base oil mixed with other chemicals (additives) to improve its properties. Engine oil is used to lubricate moving engine parts, reduce friction, protect against wear, and remove contaminants. Moreover, it can acts as a cleaning, anticorrosive and cooling agent. This study aimed to refine used engine oil by using singl...
Article
Full-text available
Phenolic compounds are essential for growth, pigmentation, resistance to pathogens, reproduction, and among others. This study focused on the optimization of microwave-assisted extraction process variables, i.e., solvent/sample ratio (X1), irradiation time (X2) and microwave power (X3), based on the yields of total phenolic content (TPC) and total...
Article
Carica papaya is a perennial large herbaceous plant known for diverse biological activities. Different parts of this plant such as seeds, leaves, fruits, peels, roots, and stems have been previously reported to possess nutritional and medicinal values. This plant possesses a nutritional value that is rich in vitamins and natural minerals but low in...
Article
Since the World Health Organization has suggested the exploration of natural products for cancer management owing to the side effects of chemotherapy and irradiation on humans and breast cancer accounts for the highest number of cancer related deaths globally, this study has examined antiproliferative effects of the aqueous and methanol extracts of...
Article
Full-text available
Hibiscus sabdariffa comprises calyx which is rich in flavonoids and numerous phytochemical compounds. Nevertheless, the extraction parameters can influence the recoveries of these bioactive compounds. It is then important to investigate the contributing effects of the process parameters and optimized their conditions to achieve higher recovery yiel...
Article
Hibiscus sabdariffa is a multi-cropping system endowed with wide ranges of benefits to humans. Being a plant rich in phenolic compounds, the process intensification of extraction method used for recovering the phenolic compounds from this essential plant is inevitable to easily proffer keen information on the extraction behaviours. Thus, the proces...
Article
Full-text available
The nutraceutical potential of black and white pepper has drawn the attention of many researchers to unravel their pharmaceutical and nutritional properties. These properties could be attributed to the presence of some essential bioactive compounds and mineral elements. This study, therefore, investigated the phenolic and mineral element compositio...
Article
Phaleria macrocarpa, commonly known as Mahkota dewa is a well-known medicinal plant native to Malaysia and Indonesia. P. macrocarpa has been used as traditional medicine for the treatment of many diseases for a long time. In this study, P. macrocarpa peels’ bioactive compounds were extracted using microwave-assisted extraction method. The effects o...
Article
Full-text available
Aloe vera is a perennial ethno-medicinal potential plant with a xerophytic characteristic, but not a cactus. It has a famous history owing to its phytopharmaceutical properties and this had made it useful in the pharmaceutical, cosmetic and food industries. Studies had shown the positive effects of its extract against bacteria, fungi, virus and par...
Article
Full-text available
Vernonia cinerea is one of the medicinal plants with several potentials for treating different ailments. In the present study, Microwave-assisted extraction (MAE) was employed in extracting phenolic compounds from this plant. However, different factors that affect this extraction method in the recovery of phenolic compounds abound, these factors ne...
Article
Full-text available
Background: Black-and white pepper extracts are natural products, which had been extensively used in food industries as a seasoning agent, and in herbal medicine for the treatment of many free radical-related diseases. Owing to the medicinal and nutritive benefits of this functional spice, the need then arises to find a way of extracting its fixed...
Article
Aloe vera is a perennial ethno-medicinal potential plant with a xerophytic characteristic, but not a cactus. It has a famous history owing to its phytopharmaceutical properties and this had made it useful in the pharmaceutical, cosmetic and food industries. Studies had shown the positive effects of its extract against bacteria, organisms. The phyto...
Article
Fatty acids are reduced carbon chains mostly found in nature with different usages in the industrial feedstock, pharmaceutical and food industries. Plants are embodiments of substantial amounts of fatty acids. In this study, gas chromatography-mass spectrometry (GC-MS) analysis was employed to identify the chemical compositions of oils from Hibiscu...
Article
Full-text available
Cancer management is associated with serious side-effects due to the harmful nature of radiation and chemotherapy on the body cells. These side-effects have necessitated the need for diversifying the alternative or complementary sources of cancer therapy. Natural products have been on the front line as alternative sources of anticancer agents and h...
Article
Phenolic compounds are secondary metabolites mainly responsible for different pharmacological activities of the plant extracts. In this study, the microwave‐assisted extraction (MAE) variables were optimized for the extraction of phenolic compounds from Chromolaena odorata leaves using a Box Behnken design of response surface methodology. concentra...
Article
Vernonia cinerea is one of the medicinal plants with several potentials for treating different ailments. In the present study, Microwave-assisted extraction (MAE) was employed in extracting phenolics compounds from this plant. However, different factors that affect this extraction method in the recovery of phenolics compounds abound, these factors...
Article
Full-text available
The bioactive compounds in Vernonia amygdalina leaf were extracted using ethanol through Soxhlet and microwave-assisted extraction (MAE) techniques. The phytochemical analysis was carried out on the ethanolic extracts using the standard techniques. This analysis revealed the presence of flavonoids, alkaloids, steroids, terpenoids, glycosides, tanni...
Article
Full-text available
The bioactive compounds in Vernonia amygdalina leaf were extracted using ethanol through Soxhlet and microwave-assisted extraction (MAE) techniques. The phytochemical analysis was carried out on the ethanolic extracts using the standard techniques. This analysis revealed the presence of flavonoids, alkaloids, steroids, terpenoids, glycosides, tanni...
Article
Full-text available
Microwave-assisted extraction (MAE) of phenolic compounds from Chromolaena odorata leaves was investigated using one-factor-at-a-time (OFAT) and two-level factorial design. The MAE parameters studied were irradiation time (A: 1–5 min); microwave power level (B: 400-800 W); extraction temperature (C: 60–80 °C); solvent/feed ratio (D: 8:1–14:1 mL/g);...
Article
Recently, unconventional methods especially microwave-assisted hydrodistillation extraction (MAHE) is being used as an alternative technique for extracting bioactive compounds from plant materials due to its advantages over conventional methods such as Soxhlet extraction (SE). In this study, bioactive compounds were extracted from Vernonia cinerea...
Article
Full-text available
Vernonia amygdalina leaf has a significant importance in food and traditional medicine. It has been reported to possess various pharmacological effects. This study was carried out to investigate the influence of microwave-assisted extraction factors on the extraction of V. amygdalina leaves. The result highlighted that increase in temperature deter...
Article
Full-text available
Fenugreek (Trigonella-Foenum Graecum) is known as one of the traditional and most promising medicinal herbs belongs to the leguminous family. The seeds of fenugreek have been extensively studied for the treatment of inflammation, cancer and diabetes. In this study, fenugreek seed oil was extracted and evaluated for its chemical compositions and bon...
Article
Full-text available
The tentative identification of bioactive compounds in the extract of Vernonia amygdalina leaf was carried out using positive ionization of Liquid chromatography-mass spectrometry quadrupole time of flight (LC-Q-TOF/MS). The positive ionization is associated with the presence of saponins, flavonoids, alkaloids, terpenoids, and glycosides. Tentative...
Article
Full-text available
The tropical white peppercorns are common commodity crops which have been traditionally used for the treatment of many free radical-related diseases. These medicinal properties are due to the presence of natural antioxidants. This study investigated the combination of microwave extraction parameters for the recovery of natural antioxidants from the...
Conference Paper
Full-text available
Phenolic compounds are important secondary metabolites with different pharmacological activities. The effects of extraction parameters of Soxhlet extraction method which include extraction time, solid-to-solvent ratio and ethanol concentration on the recoveries of extraction yields, total phenolic content (TPC) and total flavonoid content (TFC) fro...
Article
Full-text available
Emerging evidence has revealed the functional characteristics of black pepper extracts for both nutritional and medicinal purposes. The medicinal properties of this important commodity crop are due to the presence of active piperine which it a viable drug potential in ethnomedicine for the treatment of many degenerative free-radical related disease...
Article
The leaves of Vernonia cinerea are widely used for medicinal purposes. Although, different studies have reported on the biological activities of the plant extracts whereas the tentative assignment of secondary metabolites that include flavonoids, saponins, alkaloids, and terpenoids had not been reported. Thus, this study tentatively assigned the fl...
Article
Full-text available
Mushrooms are rich in pharmacologically-important phytochemicals with reported medicinal values. In this study, the antibacterial activity of Flammulina velutipes (Enoki), Hypsizygus tessellatus (brown (Buna shimeji) and white (Bunapi shimeji) variants) stem extracts prepared with different solvents (water, methanol, acetone, and ethyl acetate) was...
Article
The most daunting challenge in microwave extraction is the variability in the output quality due to inherent uncontrollable temperature factors. This study focused on how to optimize the energy absorption and reduce the effects of temperature fluctuations on extracts quality in microwave extraction of white pepper. The Taguchi Orthogonal Optimizati...
Article
Full-text available
Biosurfactants are amphiphilic compounds synthesized from plants and microorganisms. These compounds are well known to be promising alternative molecules for industrial and domestic applications due to their high biodegradability, low toxicity, multi-functionality, environmental capability, and availability of resources. In recent times, the chemic...
Article
Full-text available
The study investigated the effects of extraction parameters on the yield, antioxidant activities , morphological and functional group characteristics of black and white pepper oleoresin extracts. Optimized oleoresin yields of 5.64 and 8.72 w/w% were obtained as black and white pepper extracts, respectively. Moreover, from the antioxidant assay, the...
Conference Paper
Full-text available
Sesamum indicum L. is an herbaceous plant from the family of Padaliacea grown in tropical and subtropical part of the world. There are up to 20 species from this genus, usually grown due to the high protein from their seeds and the edibility of their leaves. It is a self-pollinated plant usually grown on the annual basis with multi-branching stem n...
Conference Paper
Full-text available
Chromolaena odorata L. is an evergreen bush that may reach 1 m or more as a shrub. Different phenolics and flavonoids that mostly protect cultured skin cells, human small cell lung, reduced oxidative degradation, and breast cancer had been isolated [1, 2]. Microwave-assisted extraction (MAE) was examined to maximize the extraction of total phenolic...
Conference Paper
Full-text available
Chromolaena odorata (Bitter bush) belongs to the family Asteraceae. It is used as a source of medicine especially in Asia and West Africa countries [1]. Phenolic compounds are mostly distributed group of phytochemicals that possess a wide range of physiological activities like antiinflammatory, anti-cancer, vasodilatory effects, antioxidant, and am...
Article
Full-text available
Black pepper is a functional plant with nutritional and medicinal benefits. Piperine being the major bioactive compound in black pepper has been applied for the treatment of many free radical-related diseases. This study determined a combination of operating parameters that optimize the microwave extraction of the piperine oil. The effect of irradi...
Article
Full-text available
The high death rate associated with cancer has fuelled the search for complementary cancer treatment methods in recent times. Among the leading alternative methods is natural products which have attracted much attention due to their high body tolerance. In this study, the caps of Flammulina velutipes (commonly called Enoki), an edible mushroom, wer...
Article
Full-text available
In this study, ethanolic microwave-assisted extraction of total phenolic content (TFC), total flavonoid content (TFC) and antioxidant from Vernonia amygdalina leaf was investigated using response surface methodology. Four extraction variables, including irradiation time (1‒5 min), microwave power level (500‒700 W), feed-to-solvent ratio (1:8‒1:12 g...
Article
Full-text available
The drying behavior of Vernonia amygdalina leaves was investigated using open sun and shade drying. The effective diffusivity coefficients for both methods were evaluated. Eight drying kinetics models were fitted to the experimental data obtained from the two drying methods; the goodness of fit was evaluated using three statistical tools, and the b...
Article
Full-text available
This paper contains data from the elemental and phytochemicalprofiling of black pepper oleoresin extracts using the LC–MS QToFand ICP-MS analysis. In recent years studies have shown the medicinal properties of extracts from these two cultivars of Pipernigrum. The medicinal properties are attributed to the presence of many secondary metabolites and m...
Article
Full-text available
Eel fish (Monopterus albus) is a functional food that has shown remarkable effects on a range of diseases, which include inflammatory diseases, type 2 diabetes and cancer. This study emphasized on the use of microwave-assisted extraction (MAE) technique in studying the effects of three MAE parameters (irradiation time, microwave temperature and mic...
Article
Full-text available
Eel fish (Monopterus albus) is a functional food that has shown remarkable effects on a range of diseases, which include inflammatory diseases, type 2 diabetes and cancer. This study emphasized on the use of microwaveassisted extraction (MAE) technique in studying the effects of three MAE parameters (irradiation time, microwave temperature and micr...
Article
Full-text available
Black pepper (Piper nigrum) is an essential tropical crop which doubled as spice in food industries and medicine in the treatment of free radical related disorders. For this study, microwave reflux method was employed in the extraction of bioactive oleoresin from black peppercorns. Extraction parameters such as irradiation time, microwave power, fe...
Article
Full-text available
Black pepper is a tropical crop with an extensive medicinal potential in ethnomedicine and nutraceutical applications. The pungent bioactive piperine is responsible for this functions which efficacy requires an efficient technologies for optimal extraction process. There is therefore a need to determine the best factor settings that optimize the re...
Article
Full-text available
The integrated bacterial mixed culture consortium with disproportionate oxygen demand was discovered to mutually cooperate with one single biofilm in oxidizing sulfide at different concentration. The present work was carried out to verify the potential of bacterial mixed culture (BMC) in developing a predictive optimum condition for sulfide oxidati...