Olugbenga Awobusuyi

Olugbenga Awobusuyi
Lagos State University | LASU · Department of Medicine

MBBS, MSc(Dist) FMCP

About

36
Publications
7,685
Reads
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620
Citations
Citations since 2016
10 Research Items
376 Citations
20162017201820192020202120220102030405060
20162017201820192020202120220102030405060
20162017201820192020202120220102030405060
20162017201820192020202120220102030405060
Additional affiliations
October 2014 - August 2017
Lagos State University
Position
  • Professor
June 2003 - present
Lagos State University
Position
  • Professor (Associate)
January 2001 - present
Lagos University Teaching Hospital
Position
  • Consultant nephrologist

Publications

Publications (36)
Article
Autosomal dominant polycystic kidney disease (ADPKD) is the most prevalent genetic disorder that results in end-stage renal disease. Although ADPKD patients experience long disease trajectories, factors such as hypertension, proteinuria and renal calculi have been observed to lead to rapid renal function impairment in patients with ADPKD. Furthermo...
Article
Introduction: The perception of death differs by region, culture, religion, and ethnic group in Nigeria. These differences can affect the consent rate for cadaveric transplantation. Understanding the Yoruba concept of death and approaching families for consent in a culturally sensitive manner may increase family consent to deceased donor organ harv...
Article
Full-text available
In organ transplantation, a wide variety of injurious events such as ischaemia-reperfusion injury, endothelial damage and the traumatic exposure of tissues during surgery occur intra-operatively. The barrage of multiple antigens presented to the recipient cause very intense immunological reaction to occur at the time of transplantation. Thus, an in...
Article
Full-text available
Background: The burden of chronic kidney disease (CKD) in Nigeria is quite alarming. The prevalence of CKD ranges from 11 - 23.5%. Hypertension and chronic glomerulonephritis (CGN) remain the two leading causes of CKD in Nigeria. The etiology of CKD in many of these patients remains unknown, as few biopsies are done. In order to demystify the vari...
Article
Full-text available
Aim The main objectives of this study were to evaluate the prevalence of zinc deficiency in a semiurban community in Nigeria and to determine its relationship with the socioeconomic status and indices of metabolic syndrome in that community. Subjects and method Serum zinc concentrations were measured in 212 subjects during a community health scr...
Article
Systemic Lupus Erythematosus (SLE) is a multi-systemic autoimmune disease. Renal involvement is a common complication, causing considerable mortality and morbidity. SLE is rarely reported among black Africans, though recent reports from Nigeria indicate otherwise. Nephritis, though a common complication of SLE has rarely been reported as the initia...
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Needle-stick and sharps injuries carry the risk of infection and are occupational hazards for all health care professionals involved in clinical care. To determine the frequency and factors contributing to needle-stick injury (NSI) among health care workers of dialysis units in Lagos, Nigeria. Data were obtained by anonymous, self-reporting questio...
Article
Full-text available
Objective: To elicit the explanatory models (EM) of hypertension among patients in a hospital-based primary care practice in Nigeria. Design. Semi-structured in-depth individual interviews and focus groups were conducted with 62 hypertensive patients. Interviews and focus groups were audiotaped and transcribed verbatim. Data analysis was guided by...
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Full-text available
In 2008, several Nigerian children developed acute kidney injury (AKI) after ingesting teething syrup contaminated with diethylene glycol (DEG). Because there are limited diagnostic facilities in resource-constrained countries, this study investigated whether AKI associated with DEG could be identified by other means. This was a multicenter study....
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Introduction Renal registries are databases containing specific disease and treatment related information about patients with renal diseases. In Nigeria, early attempts at establishing a national renal registry encountered considerable challenges as participation by centres was low and data entry by the participating centres was were inconsistent a...
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Health screening exercises are important, as they enable early detection of diseases in individual subjects and also enable data collection, useful in estimating disease burden in the community. This paper describes the findings of a health screening exercise conducted in a semiurban population of Iloye, by the Rotary Club of Ota, Ogun State, Weste...
Article
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This multi-center, randomized, parallel-group, double-blind, double-dummy study compared the efficacy and safety of chlorproguanil-dapsone-artesunate (CDA) and chlorproguanil-dapsone (CPG-DDS) in the treatment of falciparum malaria in Africa (Burkina Faso, Ghana, Mali, Nigeria). Six hundred patients (>or= 1 year of age) received CDA 2.0/2.5/4.0 mg/...
Article
Acanthosis nigricans (AN) is a dermatological condition that is often associated with obesity and may be a physical marker of insulin resistance. Studies have documented a high prevalence rate of AN in people with diabetes mellitus (DM). However, there have been no Nigerian reports on AN and DM. This report bridges the information gap and documents...
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Spontaneous adverse drug reaction (ADR) reporting is the cornerstone of pharmacovigilance. ADR reporting with Yellow Cards has tremendously improved pharmacovigilance of drugs in many developed countries and its use is advocated by the World Health Organization (WHO). This study was aimed at investigating the knowledge and attitude of doctors in a...
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Full-text available
We have identified new malaria vaccine candidates through the combination of bioinformatics prediction of stable protein domains in the Plasmodium falciparum genome, chemical synthesis of polypeptides, in vitro biological functional assays, and association of an antigen-specific antibody response with protection against clinical malaria. Within the...
Data
Questionnaire for evaluating physicians' knowledge and attitudes to ADR reporting. The questionnaire sought the demographics of the doctors, their knowledge and attitudes to ADR reporting, the factors that they perceived may influence ADR reporting, and their levels of education and training on ADR reporting.
Article
Sexual dysfunction (SD) in women with diabetes mellitus (DM) is an important but understudied aspect of DM complications in women with DM. This report is an attempt to document the prevalence, clinical correlates, and determinants of SD in a cross sectional study of women with diabetes mellitus (DM). The main outcome measures were demographic, clin...
Article
Cardiovascular diseases are prevalent in patients with end stage renal disease (ESRD). It is estimated to be responsible for 43.6% of all deaths in patients with end stage renal disease. Atherosclerotic outcomes have been shown by earlier studies to contribute significantly to these cardiovascular morbidity and mortality. Thus, assessment of C-reac...
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Full-text available
Hyperglycaemic emergencies are common acute complications of diabetes mellitus (DM) but unfortunately, there is a dearth of published data on this entity from Nigeria. This study attempts to describe the clinical and laboratory scenario associated with this complication of DM. This study was carried out in DM patients who presented to an urban hosp...
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Full-text available
Anemia is an important complication of chronic renal disease, with a significant impact on the morbidity, quality of life, and mortality in this group of patients. Inadequate erythropoietin production, reduced life span of erythrocytes in uremic serum, bone marrow suppression by uremic toxins, chronic inflammation, and contaminants in the water tre...
Article
Obtaining a vascular access for haemodialysis is very vital in the long-term management of patients with end-age renal disease. This is achieved via an autogenous (primary) arteriovenous fistula or a grafted fistula in situations where autogenous fistulas may not function. Complications such as thrombosis and infection are common following graft cr...
Article
Renal failure is a common finding in human immunodeficiency virus infected patients, and it contributes significantly to their morbidity and mortality. Most dialysis centres in Nigeria currently do not accept HIV positive patients for dialysis therapy for many reasons. The prevailing high level of stigmatization of HIV positive patients and the lac...
Article
The significance of the Modified Allen's Test has not been determined in Nigerians who need forearm arterio-venous fistulae. We sought to determine this in thirty-four patients who needed forearm arterio-venous fistulae for haemodialysis. Side-to-end radio-cephalic arterio-venous fistulae were successfully created on their forearms notwithstanding...
Article
The objective of this study was to explore the usefulness of the fractional excretion of magnesium (FEMg2+) in Nigerian chronic renal failure patients (mild to moderate) in determining the severity of renal insufficiency. Plasma and twenty-four hour urine samples were analysed for magnesium and creatinine in thirty-five chronic renal failure patien...
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Full-text available
Sickle cell disease (SCD) is predominantly a problem of black community in whom a higher prevalence of hypertension has been reported. Despite these observations, a lower mean arterial blood pressure is observed to be common in homozygous sickle cell anaemia (SCA) patients, especially from outside Africa. In view of the well known diversity in both...
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Full-text available
Students in their second year of medical studies perceived nutritional deficiency as a possible health problem in rural Nigeria and conducted a survey to investigate and compare the nutritional and health status of three distinct groups of children (Bokos in Babana, Bokos in Marami, Fulani). The nutritional status of the children in the three study...

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