Oliver Bruder

Oliver Bruder
Contilia Heart and Vascular Center Essen · Cardiology and Angiology

MD

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173
Publications
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Publications

Publications (173)
Article
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Background: Although aortic stenosis (AS) is the most common valvular heart disease in the western world, many affected patients remain undiagnosed. Auscultation is a readily available screening tool for AS. However, it requires a high level of professional expertise. Hypothesis: An AI algorithm can detect AS using audio files with the same accu...
Article
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OBJECTIVES The aim of this study was to compare the costs of a noninvasive cardiac magnetic resonance (CMR)– guided strategy vs 2 invasive strategies with and without fractional flow reserve (FFR). BACKGROUND Coronary artery disease (CAD) is a major contributor to the public health burden. Stress perfusion CMR has excellent accuracy to detect CAD....
Article
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Background Data on the prognostic value of left ventricular (LV) morphological and functional parameters including LV rotation in patients with dilated cardiomyopathy (DCM) using cardiovascular magnetic resonance (CMR) are currently scarce. In this study, we assessed the prognostic value of global longitudinal strain (GLS), global circumferential s...
Article
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The aim of this study was to investigate whether recovery from eccentric squat exercise varies depending on age and to assess whether the use of a mixed-method recovery (MMR) consisting of cold water immersion and compression tights benefits recovery. Sixteen healthy and resistance-trained young (age, 22.1 ± 2.1 years; N = 8) and master male athlet...
Article
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Background The incidence of recognized cardiopulmonary cement embolism in the context of percutaneous vertebroplasty varies between 0-23%. In most cases, only small fragments embolize in the pulmonary arteries or the right heart cavities. The latter can cause potential harm by right ventricular perforation. Case summary A 57-year-old patient was a...
Article
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Objective: To investigate the association of a wide QRS-T angle on the surface ECG and late gadolinium enhancement on contrast-enhanced cardiovascular magnetic (CMR) imaging in patients with clinically suspected myocarditis. Background: Diagnosis and risk stratification in patients with suspected myocarditis is particularly challenging due to a gre...
Article
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Objective: We sought to investigate the possible association of a wide QRS-T angle on the surface EKG and myocardial fibrosis on contrast-enhanced cardiovascular magnetic (CMR) imaging in patients with hypertrophic cardiomyopathy (HCM). Background: Risk stratification in HCM patients is challenging. Late gadolinium enhancement (LGE) visualizes myoc...
Article
Introduction The diagnosis or exclusion of obstructive stable coronary artery disease (SCAD) in clinical practice is challenging and therefore clinical guidelines provide recommendations on the use of non-invasive and invasive testing. For Germany, data obtained from the OECD and health insurances indicate a potential non-adherence to guideline-rec...
Article
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Aim: Left ventricular non-compaction (LVNC) is perceived as a rare high-risk cardiomyopathy characterized by excess left ventricular (LV) trabeculation. However, there is increasing evidence contesting the clinical significance of LV hyper-trabeculation and the existence of LVNC as a distinct cardiomyopathy. The aim of this study is to assess the a...
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Background: The QRS-T angle from the surface EKG is a promising prognostic marker in patients with coronary artery disease. Cardiovascular magnetic resonance (CMR) imaging with late gadolinium enhancement (LGE) offers high resolution imaging of myocardial damage. We investigated the association of the QRS-T angle and the extent of myocardial damage...
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Background Type 2 diabetes is a major risk factor for cardiovascular diseases, e.g. coronary artery disease (CAD). But it has also been shown that diabetes can cause heart failure independently of ischemic heart disease (IHD) by causing diabetic cardiomyopathy. In contrast to diabetes and IHD, limited data exist regarding patients with diabetes and...
Article
Purpose To prospectively evaluate contemporary indications, safety and diagnostic impact of cardiac CTA in patients undergoing cardiac CTA examinations for non-coronary clinical indications. Methods We analyzed 1,097 consecutive patients from the German Cardiac CT Registry who underwent cardiac CTA between 2009 and 2014 due to clinically indicated...
Conference Paper
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Background: Coronary artery disease (CAD) remains the leading cause of death in industrialized countries, and thus, its public health burden is important. Perfusion cardiac magnetic resonance (CMR) is generally accepted as an excellent method to detect and monitor obstructive CAD. Few studies have so far addressed its economic impact and cost-effec...
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Introduction The DANISH trial raised doubts about the effectiveness of primary prevention of sudden cardiac death by ICD implantation among patients with non-ischemic heart failure. We sought to analyse data from the EVITA-HF registry to give an answer from real-world registry data to the DANISH trial. Methods 1804 patients were identified from th...
Article
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To evaluate diagnostic impact of clinical use of coronary computed tomography angiography (CCTA) in patients with suspected stable coronary artery disease (CAD) and its consequences in daily practice for patient management, depending on stress test results in daily practice. Between 2009 and 2014 of a total population of 1352 patients of the German...
Article
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IntroductionIron deficiency (ID) has been recognized as a relevant comorbidity in heart failure with reduced ejection fraction (HFrEF); however, study data have shown that diagnostic and therapeutic efforts on ID are primarily performed in patients with anemia. Methods The RAID-HF registry investigated consecutive patients with ID and HFrEF in 11 h...
Article
Abstract Introduction: Iron deficiency (ID) in patients with heart failure with reduced ejection fraction (HFrEF) has been recognized as a clinically relevant comorbidity; however, study data have shown that diagnostic and therapeutic efforts on ID in HFrEF are primarily performed in patients with anemia. Methods: The RAID-HF study investigates man...
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Cardiac computed tomography permits quantification of coronary calcification as well as detection of coronary artery stenoses after contrast enhancement. Moreover, cardiac CT offers high-resolution morphologic and functional imaging of cardiac structures which is valuable for various structural heart disease interventions and electrophysiology proc...
Article
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Background: Coronary computed tomography angiography (CTA) is increasingly used as a test to rule out coronary artery disease (CAD) in patients with a low to intermediate pre-test probability of the disease. We used the database of the German CT registry, collected between 2009 and 2014 in a broad patient population, to analyze contemporary radiat...
Article
Background: Coronary computed tomography angiography (coronary CTA) provides non-invasive evaluation of the coronary arteries with high precision for the detection of significant coronary artery disease (CAD). Aim: To investigate whether irregular heart rhythm including atrial fibrillation and premature beats during data acquisition influences (...
Article
About 50% of all patients suffering from heart failure (HF) exhibit a reduced ejection fraction (EF ≤ 40%), termed HFrEF. The others may be classified into HF with midrange EF (HFmrEF 40–50%) or preserved ejection fraction (HFpEF, EF ≥ 50%). Presentation and pathophysiology of HFpEF is heterogeneous and its management remains a challenge since evid...
Article
Iron deficiency (ID) has been identified as an important comorbidity in patients with heart failure (HF). Intravenous iron therapy reduced symptoms and rehospitalisations of iron-deficient HF-patients in randomised trials. The present multicenter study investigated the “real-world” management of iron status in patients with HF. Consecutive patients...
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Objectives T1 mapping allows quantitative myocardial assessment, but its value in clinical routine remains unclear. We investigated, whether the average native myocardial T1 value can be used as a diagnostic classifier between healthy and diffuse diseased myocardium. Methods Native T1 mapping was performed in 54 persons with healthy hearts and in...
Article
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Coronary artery disease (CAD) continues to be one of the top public health burden. Perfusion cardiovascular magnetic resonance (CMR) is generally accepted to detect CAD, while data on its cost effectiveness are scarce. Therefore, the goal of the study was to compare the costs of a CMR-guided strategy vs two invasive strategies in a large CMR regist...
Article
Numerous reports from large cardiac magnetic resonance (CMR) imaging centers show that in almost all cases CMR-based imaging provides a comprehensive and definitive assessment of the clinical situation of patients. Therefore, cardiologists must also have unrestricted access to this imaging technique and following appropriate training should be able...
Article
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Evidence that home telemonitoring for patients with chronic heart failure (CHF) offers clinical benefit over usual care is controversial as is evidence of a health economic advantage. Between January 2010 and June 2013, patients with a confirmed diagnosis of CHF were enrolled and randomly assigned to 2 study groups comprising usual care with and wi...
Article
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Specifically we aim to demonstrate that the results of our earlier safety data hold true in this much larger multi-national and multi-ethnical population. We sought to re-evaluate the frequency, manifestations, and severity of acute adverse reactions associated with administration of several gadolinium- based contrast agents during routine CMR on a...
Article
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Background/objectives: Non-ST segment elevation myocardial infarction (MI) poses similar detrimental long-term prognosis as ST-segment elevation MI. No marker on ECG is established to predict successful reperfusion in NSTEMI. QT dispersion is increased by myocardial ischemia and reduced by successful restoration of epicardial blood flow by PCI. Wh...
Article
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The term 'athlete's heart' refers to a clinical picture characterized by a slow heart rate and enlargement of the heart. A multi-modality imaging approach to the athlete's heart aims to differentiate physiological changes due to intensive training in the athlete's heart from serious cardiac diseases with similar morphological features. Imaging asse...
Article
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Taking into account the complexity and limitations of clinical assessment in hypertrophic cardiomyopathy (HCM), imaging techniques play an essential role in the evaluation of patients with this disease. Thus, in HCM patients, imaging provides solutions for most clinical needs, from diagnosis to prognosis and risk stratification, from anatomical and...
Article
The objective of the present study was to evaluate whether integrated (18)F-FDG-PET/MRI can improve the diagnostic workup in patients with cardiac masses. Twenty patients were prospectively assessed using integrated cardiac (18)F-FDG-PET/MRI: 16 patients with cardiac masses of unknown identity and four patients with cardiac sarcoma after surgical t...
Article
The aim of this cardiac magnetic resonance (CMR) curriculum is a description of the further education process for cardiologists in order to be able to achieve expert certification in CMR. The further education CMR curriculum should provide the basis, according to three different CMR levels, for a cardiologist to assess the indications, perform and...
Article
Background: Limited data exist regarding baseline characteristics and management of heart failure with reduced ejection fraction (EF) in tertiary care facilities. Methods: EVITA-HF comprises web-based case report data on demography, comorbidities, diagnostic and therapy measures, quality of life, adverse events and 1-year follow-up of patients h...
Article
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The diagnosis of myocarditis is challenging due to its varying clinical presentation. Since myocarditis can be associated with significant 5-year mortality, and postmortem data show myocarditis in almost 10% of all adults suffering sudden cardiac death, individual risk stratification for patients with suspected myocarditis is of great clinical inte...
Article
Purpose: To assess the diagnostic accuracy of T2 mapping for the detection of myocardial edema in acute myocardial infarction (AMI), and to compare this diagnostic accuracy with that of the current standard for myocardial edema imaging, which is T2w dark-blood TSE imaging. Materials and methods: 29 patients with AMI were examined at 1.5 T. For t...
Article
Although it is well known from pathological studies that intramyocardial fat deposition frequently occurs after left ventricular myocardial infarction, a left ventricular fat deposition is rarely diagnosed in the clinical routine. We report the case of extensive fat deposition in the left ventricular myocardium which was detected by routine cardiac...
Article
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Vincenzo Klinke (vincenzo.klinke@gmail.com) Stefano Muzzarelli (stefano.muzzarelli@cardiocentro.org) Nathalie Lauriers (nlauriers@gmail.com) Didier Locca (didier.locca@chuv.ch) Gabriella Vincenti (Maria-Gabriella.Vincenti@chuv.ch) Pierre Monney (Pierre.Monney@chuv.ch) Christian Lu (Tri-Linh.Lu@chuv.ch) Detlev Nothnagel (Detlev.Nothnagel@kliniken-lb...
Article
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Cardiovascular magnetic resonance (CMR) has become an important diagnostic imaging modality in cardiovascular medicine. However, insufficient image quality may compromise its diagnostic accuracy. We aimed to describe and validate standardized criteria to evaluate a) cine steady-state free precession (SSFP), b) late gadolinium enhancement (LGE), and...
Article
Die kardiale Magnetresonanztomografie ist ein sicheres bildgebendes Verfahren mit hoher Bildqualität und klinisch bedeutsamen Indikationen und Befunden, die das Patientenmanagement stark beeinflussen. Aktuelle Weiterbildungscurricula enthalten 3 Stufen von Expertise: 1 Monat in der Basisstufe 1 (Kennenlernen von typischen Indikationen und Befunden)...
Article
Die Myokarditis stellt eine entzündliche Erkrankung des Herzmuskels dar, die verschiedenste Verläufe zeigen kann und klinisch oft schwierig zu diagnostizieren ist. Mittels endomyokardialer Biopsie (EMB) lässt sich die Diagnose (immun-)histologisch sichern, in der PCR ist auch der Nachweis von Virusgenomen, die als Auslöser vermutet werden, möglich....
Article
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Objectives: This study aimed to demonstrate that the presence of late gadolinium enhancement (LGE) is a predictor of death and other adverse events in patients with suspected cardiac sarcoidosis. Background: Cardiac sarcoidosis is the most important cause of patient mortality in systemic sarcoidosis, yielding a 5-year mortality rate between 25%...
Article
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Background: The EuroCMR registry sought to evaluate indications, image quality, safety and impact on patient management of clinical routine CMR in a multi-national European setting. Furthermore, interim analysis of the specific protocols should underscore the prognostic potential of CMR. Methods: Multi-center registry with consecutive enrolment...
Conference Paper
PURPOSE Currently T2-weighted, dark-blood prepared turbo spin echo (T2w TSE) sequences are the standard for myocardial edema imaging. Unfortunately, these sequences are prone to image artifacts. Therefore, our study aimed to compare the diagnostic accuracy of a novel T2 mapping technique with T2w TSE for visualization of myocardial edema in acute m...
Article
Objectives: To assess the diagnostic accuracy of phonocardiogram (PCG) gated velocity-encoded phase contrast magnetic resonance imaging (MRI). Methods: Flow quantification above the aortic valve was performed in 68 patients by acquiring a retrospectively PCG- and a retrospectively ECG-gated velocity-encoded GE-sequence at 1.5 T. Peak velocity (P...
Article
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Cardiovascular magnetic resonance (CMR) has favorable characteristics for diagnostic evaluation and risk stratification of patients with known or suspected CAD. CMR utilization in CAD detection is growing fast. However, data on its cost-effectiveness are scarce. The goal of this study is to compare the costs of two strategies for detection of signi...
Article
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Exercise electrocardiography (ECG) is frequently used in the work-up of patients with suspected coronary artery disease (CAD), however the accuracy is reduced in women. Cardiovascular magnetic resonance (CMR) stress testing can accurately diagnose CAD in women. To date, a direct comparison of CMR to ECG has not been performed. We prospectively enro...