Olga Maria Duarte Silva

Olga Maria Duarte Silva
University of Lisbon | UL · Faculty of Pharmacy, Pharmacological Sciences Department

PhD

About

91
Publications
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1,070
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January 2003 - December 2012
University of Lisbon
January 2000 - present

Publications

Publications (91)
Article
Full-text available
Dried leaves of Satureja khuzestanica Jamzad are a popular herbal medicine and dental anesthetic among the nomadic inhabitants of southwestern Iran. The present study establishes criteria for identification of S. khuzestanica dried whole, fragmented and powdered leaves for specification as a herbal substance using macroscopic and microscopic charac...
Article
Terminalia macroptera Guill. and Perr. (Combretaceae) is a species used to treat infectious diseases in many West African countries. Previously, root and leaf hydro ethanol extracts of this species showed an interesting profile of activity against Neisseria gonorrhoeae [1,2]. The root extract of this species also showed to be active against enterop...
Article
Full-text available
The ethanolic extracts of twelve plants selected through ethnomedical survey in Guinea-Bissau were investigated for their in vitro antimicrobial properties over ten bacteria and Candida albicans, using agar diffusion and dilution methods. All the tested extracts showed some activity against at least one of the bacteria. Most of the extracts (79%) s...
Conference Paper
Full-text available
Set of Books 1-6 reporting a comprehensive Survey of Native Food Production in Mexico, Central America (Sapperland) Greece and Peru, gathered in the XVI International Ethnobotany Symposio, held at Cusco, September 2018., with the High Auspices of National University S. Antonio Abad and local and Regional Delegates, involved in Food Production, main...
Conference Paper
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The Book 2 of Proceedings, Ethnobotany Smposio, Cusco, Peru, is comprehensive of five papers that cover Current Research in Frontier Agroecology, Economic Botany Permaculture, and native production, in various environmental scenarios: Mexico, Peru, Greece. They constitute Models for sustainable Food Production in the forthcoming years.
Article
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Geopropolis collected by stingless bees is a product widely used in the semiarid Northeast region of Brazil. The wound healing activity, palynological analysis, free-radical scavenging activities, and the chemical composition of the hydroalcoholic extract of six samples from jandaíra geopropolis were determined. The wound healing activity was evalu...
Conference Paper
Full-text available
Ayahuasca is a South American traditional herbal preparation typically produced by decoction of a mixture of Banisteriopsis caapi stem and Psychotria viridis leaf. Among others, it contains as marker compounds the psychedelic 5-HT2A and sigma-1 agonist N,Ndimethyltryptamine (DMT) from P. viridis plus β-carboline alkaloids with monoamine-oxidase (MA...
Article
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Sea hares of Aplysia genus are recognized as a source of a diverse range of metabolites. 5α,8α-Endoperoxides belong to a group of oxidized sterols commonly found in marine organisms and display several bioactivities, including antimicrobial, anti-tumor, and immunomodulatory properties. Herein we report the isolation of 5α,8α-epidioxycholest-6-en-3β...
Article
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Ethnomedicine focuses on empirical and traditional knowledge of healing practices of different human groups, including the use of plants as medicine. We aimed to determine whether there is consensus regarding the use of plants in traditional medicine of Afro-descendant communities in Brazil, Europe and Africa. Data were obtained through interviews,...
Article
The phenolic profile and antioxidant activity of Cape Verde's Artemisia gorgonum Webb and Hyptis pectinata (L.) Poit. infusions before and after in vitro simulation of the gastrointestinal digestion were determined. The LC-UV/DAD fingerprinting analysis allowed the identification of 3-O-caffeoylquinic acid, chlorogenic acid, 3,5 dicaffeoylquinic ac...
Article
The profile of essential and non-essential elements was traced in the edible sea hares Aplysia depilans Gmelin, Aplysia fasciata Poiret and Aplysia punctata Cuvier. Manganese (Mn), iron (Fe), zinc (Zn), copper (Cu) and selenium (Se) were identified as the major essential elements. Risk assessment evidenced that the levels of cadmium (Cd) and lead (...
Article
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Plant-based systems continue to play an essential role in healthcare, and their use by different cultures has been extensively documented. Asphodelus L. (Asphodelaceae) is a genus of 18 species and of a total of 27 species, sub-species and varieties, distributed along the Mediterranean basin, and has been traditionally used for treating several dis...
Chapter
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Ethnopharmacological studies on antimicrobial traditional herbal preparations have gained much attention in recent years. In fact, in the last 30 years, 2/3 of the new antibacterial drugs were of natural source and among them, plants were mainly used. In addition, the emergence of new drugs active against resistant strains (e.g. the ESKAPE pathogen...
Chapter
Full-text available
Standardization and quality control are essential analytical tools to assure the correct identification of herbal raw materials in order to be used as herbal medicines. In this context, scientific work concerning the establishment of botanical biomarkers based on the major microscopic features observed using light microscopy and scanning electronic...
Article
The aerial part of Hypericum foliosum showed similar major classes of constituents to Hypericum perforatum. However, H. foliosum belongs to Androsaemum section, as Hypericum androsaemum, characterized by absence of hypericins. To compare the in vivo antidepressant activity of methanol extracts from aerial part of these three species, based on fact...
Article
Anacardium occidentale L. (cashew tree) has been traditionally used to treat type 2 diabetes. Hereby we present results of free radical scavenging activity assay and in vivo toxicity and genotoxicity tests on red and white cashew stem bark Portuguese traditional herbal preparations (CSBTHPs) used to control type 2 diabetes, standardized on the basi...
Chapter
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Species of Terminalia L. genus (Combretaceae) were worldwide used in traditional medicine to treat different kind of diseases. In Africa, 30 Terminalia species were described and the traditional uses of most of it as antimicrobial agents were reported by different authors. In the present work a summary of the principal studies and results concernin...
Article
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Frangula azorica V. Grubow is a Macaronesian flora medicinal plant, endemic from Azores islands and inscribed on the International Union for the Conservation of Nature (IUCN) Red List of Threatened Species. This species, known as “sanguinho,” belongs to the family Rhamnaceae, the same as Frangula alnus Mill. and Frangula purshiana (DC.) J. G. Coope...
Article
Gymnosporia arenicola Jordaan (Celastraceae) is a shrub or small tree, which naturally occurs in coastal sand dunes of Southern Mozambique and South Africa. Its dried leaf is often used in traditional medicine for the treatment of infectious and inflammatory diseases. Hereby, we present results of studies carried out according to the pharmacopoeia...
Article
The isolation and structural elucidation of a macrocyclic alkaloid, characterized by the presence of a 13-membered macrolactam ring containing a spermidine unit N-linked to a benzoyl group is hereby reported. The structure of this previously unknown spermidine alkaloid isolated from Gymnosporia arenicola (Celastraceae) leaves has been elucidated by...
Article
Times Cited: 0 RUDIGERSTR 14, D-70469 STUTTGART, GERMANY STUTTGART Meeting Abstract AU4AB English P2B100 Cited References Count: 3
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Times Cited: 0 RUDIGERSTR 14, D-70469 STUTTGART, GERMANY STUTTGART Meeting Abstract AU4AB English P2040 Cited References Count: 4
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Times Cited: 0 RUDIGERSTR 14, D-70469 STUTTGART, GERMANY STUTTGART Meeting Abstract AU4AB English P2B36 Cited References Count: 4
Chapter
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The dried leaf of Digitalis purpurea L. (foxglove leaf) was introduced as botanical drug into the London Pharmacopoeia of 1650 and remains actually in all Occidental Pharmacopoeias (digitalis purpureae folium). During last year's, some specimens of Digitalis L. genus collected in the Northeast region of Portugal were identified by us as natural hyb...
Article
This experimental work aimed to develop a simple, fast, economic and environmental friendly process for the extraction of lycopene from tomato and incorporate this lycopene-rich-extract in ultradeformable vesicular nanocarriers suitable for topical application. The lycopene extraction was carried out without a co-solvent for 30 min. The extracts we...
Article
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Moringa oleifera is a plant native of Asia that contains medicinal and nutritional properties that have proved to be of great interest to Mozambique. This specie has been popularly used in the country, but few scientific studies prove that its full potential has been developed. To give scientific support, studies are being developed on the chemical...
Article
Full-text available
Moringa oleifera is a plant native of Asia that contains medicinal and nutritional properties that have proved to be of great interest to Mozambique. This specie has been popularly used in the country, but few scientific studies prove that its full potential has been developed. To give scientific support, studies are being developed on the chemical...
Article
Full-text available
Digitalis purpurea L. and Digitalis thapsi L. (Iberian endemism) are two well known Portuguese species that contain cardiac glycosides. Last year we found some specimens in the Northeast region of Portugal that appeared to us to be natural hybrids between D. purpurea and D. thapsi. In consequence, morphological, genetic and chemical experimental wo...
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Times Cited: 0 RUDIGERSTR 14, D-70469 STUTTGART, GERMANY STUTTGART Meeting Abstract 982KT English Cited References Count: 0
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Times Cited: 0 RUDIGERSTR 14, D-70469 STUTTGART, GERMANY STUTTGART Meeting Abstract 982KT English Cited References Count: 0
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Times Cited: 0 RUDIGERSTR 14, D-70469 STUTTGART, GERMANY STUTTGART Meeting Abstract 982KT English Cited References Count: 0
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Times Cited: 0 RUDIGERSTR 14, D-70469 STUTTGART, GERMANY STUTTGART Meeting Abstract 982KT English Cited References Count: 0
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Times Cited: 0 RUDIGERSTR 14, D-70469 STUTTGART, GERMANY STUTTGART Meeting Abstract 982KT English Cited References Count: 0
Conference Paper
Portuguese Flora includes the known species Digitalis purpurea L. and the endemism of Iberian Peninsula Digitalis thapsi L. with different morphological and chemical characteristics. Until now, and in spite of their economic importance, related to the cardenolides presence, little information is available concerning the genetic diversity of the na...
Article
The root of Terminalia macroptera Guill. & Perr. (Combretaceae) is widely used in African traditional medicine to treat various infectious diseases, including stomach-associated diseases. This study investigates the in vitro activity of T. macroptera root extract against reference strains and clinical isolates of H. pylori and attempts to localize...
Article
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Maytenus heterophylla (Eckl & Zeyh.) Robson and Maytenus senegalensis (Lam). Exell are two African medicinal plants used to treat painful and inflammatory diseases. We evaluated the in vivo (per os) anti-inflammatory activity of M. heterophylla leaf, stem and root extracts and of M. senegalensis leaf and stem extracts. Additionally, we assessed the...
Article
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Maytenus heterophylla (Eckl. and Zeyh.) N.K.B. Robson and Maytenus senegalensis (Lam.) Exell are two African shrubs or trees that go under the common name of spike thorn, which belong to the Celastraceae family. Different plant parts of this species are largely used in traditional medicine for infectious and inflammatory diseases treatment. Several...
Conference Paper
Full-text available
Many biomedical devices work with micellar microflows. The fluids are mainly non Newtonian because of the micelles. These can be red cells, proteins, chemical components, etc… whose flow can interfere in the original organization. This article provides an experimental investigation of an in vitro real and untreated rabbit blood micro-flow. The rabb...
Conference Paper
Full-text available
Diospyros villosa L. (de Winter) root is used as toothbrush and to treat oral infections in Mozambique. This medicinal plant is known as “mulala” a vernacular name also common to Euclea natalensis A.DC. root, another Ebenaceae species with the same traditional uses. The antimicrobial activity of E. natalensis root against diverse microorganisms is...
Article
Microscopical characters are well established criteria in the identification and authentication of herbal drugs. Leaves of Euclea natalensis A. DC. (Ebenaceae) are commonly used in the treatment of headache and toothache, as well as for abdominal complaints and as purgative [1]. The purpose of this study was to determine the most relevant diagnosti...
Article
The genus Terminalia (Combretaceae) is known as a source of bioactive secondary metabolites. This work aims at the in vitro activity of leaf and root hydroethanol extracts of Terminalia boivinii Tul., Terminalia sambesiaca Engl. and Diels and Terminalia spinosa Engl. against nine N. gonorrhoeae penicillin and tetracycline sensitive and resistant st...
Article
Moringa oleifera Lam. (Moringaceae), commonly known as "drumstick tree" or „horse radish tree“ is native to north India but is now found throughout the tropics. Leaves of this high medicinal value plant have been reported to have antihypercholesterolemic action [1] and those with other risk factor, such as hypertension [2] or diabetes mellitus [3]....
Article
Dried fruits of Lonicera caerulea var. altaica (Caprifoliaceae) are used in traditional Mongolian medicine to treat liver, stomach and cardiac diseases [1]. Although some previous comparative studies were reported on the Lonicera genus [2], there aren't any studies on the morphoanatomical characterization of the fruits of L. caerulea var. altaica (...
Article
Terminalia macroptera Guill. and Perr. (Combretaceae) is a West African species used on traditional medicine to treat infectious diseases.[1] Hereby we present the results of an antimicrobial activity screening performed by the twofold serial microdilution assay against seven reference bacterial strains and against Candida albicans, with a leaf hyd...
Article
Full-text available
Diospyros villosa L. (de Winter) root is used as toothbrush and to treat oral infections in Mozambique. This medicinal plant is known as "mulala" a vernacular name also common to Euclea natalensis A.DC. root, another Ebenaceae species with the same traditional uses. The antimicrobial activity of E. natalensis root against diverse microorganisms is...
Article
Diospyros villosa L. (de Winter) var. villosa (Ebenaceae) is an African shrub, which naturally occurs in Mozambique. Roots of D. villosa are used in the local traditional medicine as cathartic remedy for stomach and intestinal complaints [1]. The present work aims to establish botanical criteria to determine most relevant morphological roots featur...
Article
Full-text available
Calycobolus heudelotii (Baker ex Oliv.) Heine is a native plant from West Tropical Africa. Stems are used in folk medicine of Guinea-Bissau for inflammations, skin allergies and wounds [1]. First work previously performed was a preliminary botanical analysis of the stem [2]. Here we present results from an antimicrobial activity study of C. heudelo...
Chapter
Full-text available
Herbal drug technology includes all the necessary steps for the conversion of botanical materials into medicines, where standardization and quality control are essential analytical tools to assure the correct identification of drugs. Advances in microscope technology and improvements in light and scanning electron microscopes have increased the acc...
Conference Paper
Maytenus heterophylla (Eckl. & Zeyh.) N. Robson (Celastraceae) is a shrub or tree, growing in the semidesertic regions of both Asia and Africa. Different plant parts of this species are largely used in traditional medicine for infectious and inflammatory diseases treatment [1]. Some biological activity studies were already performed confirming the...
Conference Paper
Hypoxis hemerocallidea Fisch. & C.A. Mey. (Hypoxidaceae) plants are geophytic and they overcome winter conditions in the form of an underground rootstock called the corm. The plant grows well in warm and cold subtropical areas and the planting of the young corms should be done during the spring season. They also have adventitious roots attached to...
Article
Lannea stuhlmanni, Maytenus heterophylla, Maytenus senegalensis, Sarcostemma viminale and Tabernaemontana elegans are medicinal plants used in Mozambique to alleviate symptoms and treat pulmonary diseases, including tuberculosis [1]. Hereby we present results from an ethnopharmacological study conducted in order to validate the traditional use of t...
Article
Leaves of Maytenus heterophylla (Eckl & Zeyh.) Robson (Celastraceae) are used in East Africa to treat different diseases such as infections, respiratory diseases and sores [1]. Despite some chemical studies have already been reported for this part of the plant, respective biological studies are scarce and there is a lack of studies aiming at its' b...
Article
Full-text available
Frangula azorica V. Grubow (Rhamnaceae), locally known as “sanguinho”, is an Azorean endemism inscribed on the IUCN Red List of Threatened Species. Morphological, chemical and biological studies on F. azorica are scarce, but preliminary studies on the bark of this species enable the identification of anthraquinone derivatives as major compounds of...
Article
In this communication we present the Center of Research and Development in Ethnobotany, created by the Scientific Council on Ethnobotany (COCIE) of the Ministry of the Science and Technology of Mozambique. This center, located at Namaacha and inaugurated in June of 2009, is responsible for the coordination of the research activities, interconnectio...
Article
Medicinal extracts of Maytenus heterophylla (Eckl & Zeyh.) Robson and M. senegalensis (Lam.) Exell used in Mozambican traditional medicine to treat painful and inflammatory conditions were evaluated for their anti-inflammatory potential. Thus, leaf, stem, and root extracts of M. heterophylla and the leaf and stem extract of M. senegalensis were tes...
Conference Paper
Maytenus heterophylla and Maytenus senegalensis are two major species from the Celastraceae family, both consisting of medicinal plants from Mozambique, traditionally used to treat respiratory and inflammatory diseases. Previous studies have confirmed anti-inflammatory activity of Maytenus senegalensis root extracts and of maytenoic acid, in vivo....