Olena Litvinova

National University of Pharmacy · Department of Management and Quality Assurance in Pharmacy

The aim of the work is analysis of the current state and trends in the metformin-based drug development with the subsequent formation of the logistics system of scientific research. Materials and methods. Studies were conducted using databases on the Internet (2015-2022): PubMed; U.S. Food and Drug Administration, European Medicines Agency, the St...

The modern healthcare system is directly related to the development of digital health tools and solutions. Pills with digital sensors represent a highly innovative class of new pharmaceuticals. The aim of this work was to analyze the patent landscape and to systematize the main trends in patent protection of digital pills with ingestible sensors wo...

Objectives: Digital pills are new technologies that aim to improve healthcare by increasing medication adherence. The aim of the work was a bibliometric analysis of clinical studies of digital pills and an assessment of the level of evidence of their effectiveness, safety, and prospects for the future. Materials and Methods: The studies were conduc...

Aim: This study aimed to identify and analyze the top 100 most cited digital health and mobile health (m-health) publications. It could aid researchers in the identification of promising new research avenues, additionally supporting the establishment of international scientific collaboration between interdisciplinary research groups with demonstrat...

Adverse drug reactions continue to be not only one of the most urgent problems in clinical medicine, but also a social problem. The aim of this study was a bibliometric analysis of the use of digital technologies to prevent adverse drug reactions and an overview of their main applications to improve the safety of pharmacotherapy. The search was con...

This study conducted a comprehensive patent and bibliometric analysis to elucidate the evolving scientific landscape surrounding the development and application of pulse oximeters, including in the field of digital medicine. Utilizing data from the Lens database for the period of 2000–2023, we identified the United States, China, the Republic of Ko...

Background The digitalization of medicine is becoming a transformative force in modern healthcare systems. This study aims to investigate discussions regarding patient safety, as well as summarize perceived approaches to mitigating risks of adverse events expressed through the #PatientSafety Twitter hashtag during the COVID-19 pandemic. Methods Th...

Non-alcoholic fatty liver disease (NAFLD) is defined as a clinical syndrome characterized by excessive fat accumulation in liver, predominantly influenced by dietary choices. This study provides an extensive quantitative literature analysis on dietary influences on NAFLD. Bibliometric data were collected through the search string TOPIC = (“NAFLD*”...

The aim: development of methodological approaches to assessing the digital maturity of the logistics activity of a pharmaceutical enterprise and elaboration of the proposed methodology on the example of those domestic enterprises that have a developed logistics system and some experience in the implementation of digital technologies in logistics ac...

The high need for optimal diabetes management among an ever-increasing number of patients dictates the development and implementation of new digital sensors for continuous glucose monitoring. The purpose of this work is to systematize the global patenting trends of digital sensors for continuous glucose monitoring and analyze their effectiveness in...

Objectives Continuous non-invasive monitoring of blood pressure is one of the main factors in ensuring the safety of the patient’s condition in anesthesiology, intensive care, surgery, and other areas of medicine. The purpose of this work was to analyze the current patent situation and identify directions and trends in the application of non-invasi...

Aim. To analyze the current trends in the field of digitalization of pharmaceutical logistics and supply chain management in the context of the coronavirus pandemic and identify factors that hinder the introduction of digital technologies into the activities of pharmaceutical market entities. Materials and methods. To achieve the goal of the study,...

The purpose of the publication is to analyze and systematize statistical data on the resulting waste (including medical) in Ukraine in the context of COVID-19 and problems of medical waste management. On the basis of the analysis on waste management in Ukraine, a number of problems were identified. There is an increase in the volume of waste every...

Research is devoted to the development of theoretical, methodological and scientific-practical principles of management of socially responsible activities of domestic pharmaceutical companies as a key condition for improving the quality, efficiency and accessibility of pharmaceutical supply, which is especially relevant in a global pandemic, closin...

The aim of the work is to form a mandatory methodology "Conformity Assessment" within the framework of the implementation of environmental and energy management systems in the context of the formation of an integrated management system at a pharmaceutical enterprise. The development and implementation of an integrated quality system at a pharmaceut...

The global economic crisis, which is linked to the coronavirus pandemic, has also affected pharmaceutical logistics. Therefore, the improvement of logistics processes within the pharmaceutical supply chain to increase the access to health care to the population in a pandemic becomes especially important. The aim of the work is to study and summariz...

The aim of the work is to analyze and generalize the existing scientific approaches and substantiate the mechanisms of formation of the logistics innovation system of the pharmaceutical company, which is the most important condition for creating modern effective domestic drugs under optimal use of resources and time. Materials and methods. Studies...

Мета роботи: аналіз й узагальнення існуючих наукових підходів і механізмів щодо управління інноваційною діяльністю при розробці та реєстрації лікарських засобів для лікування коронавірусної хвороби (COVID-19) на основі упровадження логістичного підходу і створення інтегрованої логістичної інноваційно-інформаційної системи.Матеріали та методи: бази...

Мета: обґрунтування необхідності впровадження сучасних технологій та інструментів логістики у сферу лабораторних досліджень для забезпечення необхідного рівня якості та ефективності їх проведення.Матеріали та методи. Для досягнення мети дослідження проведено аналіз закордонної і вітчизняної наукової літератури та чинної нормативно-правової бази Укр...

The aim of the work is to analyze and systematize data regarding the efficacy and safety of anti-tumor necrosis factor-α biosimilars, as well as their registration and patenting. Studies were conducted using databases on the Internet: Ukrainian patent office, the European patent office, the US patent office, the Food and drug administration, Europe...

The aim of the work is to analyze and systematize the literature data regarding the current state and strategic aspect of intravenous use of diclofenac for the prevention of postoperative pain, namely clinical efficacy and safety. Materials and methods. Studies were conducted using databases on the Internet: PubMed; Food and Drug Administration, E...

Multiple sclerosis is predominantly affected by young people, usually beginning at the age of 20 to 40 years and is the most common cause of non-traumatic disability in the adult population. The aim of the work is the analysis and systematization of literature data on the the availability of therapy for multiple sclerosis with immunomodulators and...

Розсіяний склероз (РС) вражає осіб переважно молодого віку, зазвичай починається у віці від 20 до 40 років і є найбільш частою причиною нетравматичної інвалідизації серед дорослого населення.Метою роботи є аналіз та систематизація даних літератури стосовно доступності терапії РС імуномодуляторами та імуносупресантами в Україні.Результати. Представл...

The purpose of the study was to analyze and systematize the literature data on the benefit/risk ratio of sofosbuvir administration in the treatment of patients with chronic hepatitis C and the main trends in its patent protection. Studies were conducted using databases on the Internet: Ukrainian patent office, the European patent office, the US pat...

The aim of the work is to analyze and systematize literature data on the benefits of clinical and economic efficiency, safety of cetuximab in the treatment of colorectal cancer. Materials and methods. Studies were conducted using databases on the Internet: PubMed; Food and Drug Administration, European Medicines Agency. It has used retrospective,...

Мета роботи. Аналіз стану і тенденцій розвитку державно-приватного партнерства (ДПП) за кордоном при рішенні глобальних проблем при створенні інноваційних лікарських засобів (ЛЗ) для лікування соціально загрозливих захворювань, узагальнення світового досвіду щодо доцільності використання певних інструментів ДПП і розробка системи індикаторів для оц...

The aim of the work. Analysis of the state and development trends of public-private partnerships (PPP) abroad in solving global problems in creating innovative drugs for the treatment of socially significant diseases, generalizing world experience of the feasibility of using certain PPP tools and developing the system of indicators to assess the ef...

In the conditions of innovative pharmacy development the problem of theoretical and scientific-practical approaches to intellectual resources management of drug developers and manufacturers becomes of a particular urgency.Aim. To diagnose the main problems in the field of intellectual resources management in pharmacy and to identify the reserves fo...

The aim of the work is to analyze and systematize existing scientific approaches and mechanisms for the formation of innovation development strategies in pharmacy. Materials and methods. Studies were conducted using a database on the Internet: Ukrainian patent office, SE “The State Expert Center” of the Ministry of Health of Ukraine, scientometric...

The aim of this study was to analyze Ukrainian pharmaceutical market and patent protection of antiretroviral drugs in Ukraine and abroad. It has established that in Ukraine most of medicines are foreign antiretroviral drugs under patent protection. Take into account the prevalence of HIV in Ukraine the introduction into clinical practice domestic g...

Охорона об’єктів інтелектуальної власності (ОІВ) є необхідною умовою для впровадження інновацій, зниження інноваційних ризиків, а також фінансування R&D з розробки лікарських засобів (ЛЗ). Метою роботи є аналіз і узагальнення існуючих наукових підходів і механізмів до комерціалізації інтелектуальної власності у фармації для побудови процесної модел...

Currently, the state and effectiveness of intellectual resources management system define competitiveness, strategic position and prospects of the development of modern pharmaceutical companies. The aim is to study scientific and methodological approaches to the assessment and management of intellectual resources of domestic pharmaceutical compani...

Проведено аналіз ефективності управління інтелектуальними ресурсами у 15 провідних вітчизняних ВНЗ медичного та фармацевтичного профілю за період 2013-2014 рр., визначені резерви подальшого удосконалення цієї діяльності. Запропоновано модель управління інтелектуальними ресурсами, яка дозволяє суттєво розширити можливості ВНЗ щодо накопичення необхі...

The aim of this study was to analyze features of thepatent researches of nanotechnology-based drug development. It has offered the algorithm of thepatent researches, which takes into account thesearchin patentdatabasesand scientificresources, the use of the InternationalPatent Classification, the European Classification, the United States Patent Cl...

Introduction. Currently, the problem of identifying orphan diseases and their treatment is acute and complex issue for most countries, including the Ukraine. It should be noted the lack of information on the prevalence of these diseases, diagnostics limitations, lack of medicines or their high cost. There is the question to pharmaceutical companies...

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