Oleksandr Topachevskyi

• PG Dip, Health Economics
• Economist at Digital Health Outcomes

Market access for pharmaceuticals is a set of strategies, activities and processes developed by pharmaceutical companies to provide affordable medicines at appropriate fair prices in a particular health care system. Access to the pharmaceutical market covers main areas of stages, including the health technology assessment (HTA). The aim of the wor...

Background: Increasingly, multi-criteria decision analysis has gained importance as a method by which to assess the value of orphan drugs. However, very little attention has been given to the weight (relative preferences) of the individual criteria used in a framework. Aims: This study sought to gain an understanding of the preferential weights tha...

ESTIMATION OF SUPPLY SIDE COST EFFECTIVENESS THRESHOLD IN UKRAINE: PERSPECTIVE USE IN HEALTH CARE DECISION-MAKING Topachevskyi O1, Piniazhko O1, Lebega O2 , Oleshchuk O3 1Member of the National EML Committee, Kyiv, Ukraine 2Technical SAFEMED Advisor 3Head of the National EML Committee, Kyiv, Ukraine OBJECTIVE Estimate supply side cost effective...

Background: Many countries struggle with the prioritisation of introducing new vaccines because of budget limitations and lack of focus on public health goals. A model has been developed that defines how specific health goals can be optimised through immunisation within vaccination budget constraints. Methods: Japan, as a country example, could...

OBJECTIVES: To understand the key functional differences between conventional cost-effectiveness Excel and web based model types. METHODS: An online survey consisting 18 end users and 5 model owners (n=23) was conducted. Respondents were asked to rate key criteria of both model types on a scale from 0 to 10. Model types were compared with the follo...

OBJECTIVES: To inform decision makers who seek extension of Universal Mass Vaccination (UMV) about the most optimal allocation of funds across multiple preventative interventions or vaccines. To account for decision makers preferences using MCDA. METHODS: A multi cohort markov model was developed to assess clinical and economic consequences of vacc...

Various online services such as Socialbakers, Keyhole, Gnip offer tools to analyze, fetch and collect data from social media. This data is often presented in a form of interactive web based dashboards, displaying various trends: number of posts, mentions, shares, likes over time. Facebook and Twitter have an API to access data on social media profi...

Objectives To compare the cost-effectiveness of a universal mass vaccination (UMV) program with a 2 + 1 schedule of a 10-valent pneumococcal polysaccharide nontypeable Haemophilus influenzae protein D conjugate vaccine (PHiD-CV) against two strategies: 1) a no-vaccination strategy and 2) a pneumococcal 13-valent conjugate vaccine (PCV13) 2 + 1 stra...

Objectives� The model aims to determine the optimal allocation of financial resources amongst various paediatric vaccines accounting for changes in budget and availability of new vaccines over time. This approach aims to inform decision makers who are seeking to extend their national immunisation programmes about the optimal mix of vaccines and seq...

The clinical and economic burden associated with invasive and non-invasive pneumococcal and non-typeable Haemophilus influenzae (NTHi) diseases is substantial in the Latin America and Caribbean region, where pneumococcal vaccines have only been introduced to a few countries. This study analyzed the cost-effectiveness and cost utility of three diffe...

Background Pneumococcal universal vaccination in Hong Kong was introduced in 2009.Objectives We assessed the health and economic impact of the 10-valent pneumococcal nontypeable Haemophilus influenzae protein D conjugate vaccine (PCV-10) compared with the current 13-valent pneumococcal conjugate vaccine (PCV-13) recommended for Hong Kong in 2011, p...

OBJECTIVES: To compare the clinical and economic burden of community acquired pneumonia (CAP) with invasive pneumococcal diseases (IPD) in children less than 10 years of age, based on cost-effectiveness studies from 7 countries. METHODS: The clinical and economic burden of IPD and CAP hospitalisations in children less than 10 years of age over 1 ye...

Background Streptococcus pneumoniae infections, which place a considerable burden on healthcare resources, can be reduced in a cost-effective manner using a 7-valent pneumococcal conjugate vaccine (PCV-7). We compare the cost effectiveness of a 13-valent PCV (PCV-13) and a 10-valent pneumococcal non-typeable Haemophilus influenzae protein D conjuga...

We evaluated national rotavirus (RV) immunization programme costs to estimate how resulting changes in morbidity and mortality will influence government fiscal accounts over time. The assumption was that increased childhood survival in vaccinated cohorts leads to increased numbers of children consuming government resource, and an increased number o...