Oleksandr Kovalchuk

Oleksandr Kovalchuk
National Taras Shevchenko University of Kyiv | Київський національний університет імені Тараса Шевченка · Educational and Scientific Centre “Institute of Biology and Medicine”

Professor. D.Med.S.
www.anatom.ua

About

41
Publications
6,875
Reads
How we measure 'reads'
A 'read' is counted each time someone views a publication summary (such as the title, abstract, and list of authors), clicks on a figure, or views or downloads the full-text. Learn more
82
Citations
Introduction
Head of the Department of Anatomy and Pathological Physiology at Educational And Scientific Centre “Institute of Biology and Medicine” of Taras Shevchenko National University of Kyiv
Additional affiliations
October 2019 - present
National Taras Shevchenko University of Kyiv
Position
  • Head of Department
Description
  • https://biology.univ.kiev.ua/institute-activity/educational/kafedry/kafedra-anatomii-ta-patolohichnoi-fiziolohii/pro-kafedru.html
September 2004 - June 2019
Bogomolets National Medical University
Position
  • Professor (Assistant)
Education
September 1998 - June 2004
Bogomolets National Medical University
Field of study
  • General Medicine

Publications

Publications (41)
Article
The article presents data relating to structural changes in rat adenohypophysis in experimental burn disease and its treatment. Experimental studies were conducted for defining peculiarities of structural changes in rats' adenohypophisis without and after skin burn injuries (in 7-14 and 21-30 days) alongside its correction with 0.9% NaCl solution....
Article
Full-text available
ABSTRACT The aim: Was to compare the changes in hematological parameters of blood in the conditions of prolonged exposure of lead sulfide nanoparticles (NP) of different sizes and of lead nitrate. Materials and methods: The study was conducted on mature male Wistar rats 160-180 g, intraperitoneally injected with Pb(NO3)2 and NP PbS of 26-34 nm and...
Article
Full-text available
Background: Ocular trauma and its sequelae substantially affect quality of life. Effective methods to promote regeneration of damaged optic nerve (ON) are still to be developed. Purpose: To investigate structural changes in the rat ON after experimental ON injury followed by treatment with stem cells. Materials and Methods: After being subjected to...
Article
Full-text available
Резюме. Актуальність даного дослідження обумовлена відсутністю спеціальних досліджень предме-том яких є аналіз показників ендогенної інтоксикації та структурних змін гістогематичних бар’єрів органів нейроімуноендокринної системи при опіковій хворобі за умов її лікування шляхом інфузії ко-лоїдно-гіперосмолярних розчинів. Встановлено, що особливе зна...
Article
Akkermansia muciniphila (A. muciniphila) is a mucin-degrading bacterium that commonly lives in the intestinal mucus layer. It is normally detected in human faecal specimens and is one of the few bacteria potentially associated to obesity development. In this narrative review, possible mechanisms that support how A. muciniphila is implicated in the...
Chapter
The worldwide prevalence of obesity more than doubled between 1980 and 2014. The most frequent cause which leads to the obesity development is a dysbalance between energy intake and energy expenditure. In this complex process genetic susceptibility, environmental and lifestyle factors are involved. Consequently, the gut microbiota is gaining signif...
Article
deterioration of epidemiological situation in the country and educational institutions due to the spread of coronavirus infection prompted the government to change the educational process and move it to distance learning. Psychological support and assistance of future doctors are critical, as, in our country, there is a growing shortage of medical...
Article
Full-text available
З огляду на значний прогрес у розвитку медицини за сучасних інтенсивних соціально-економічних змін, необхідність у формуванні професійно орієнтованих знань лікарів різного профілю, підвищення вимог до професійних навичок фахівців, є очевидною необхідність оптимізації існуючих і розробка нових методів та засобів навчання. Застосування в навчанні інн...
Article
Full-text available
Історичний розвиток науки неможливий без урахування зв’язків з усім попереднім досвідом людства. Всі медичні науки, в тому числі і анатомія, мають свою історію, тобто весь пройдений шлях розвитку і вдосконалення. Велике значення в розвиток як вітчизняної анатомічної науки, так і Київської анатомічної школи, внесли жінки-науковці. Окрім цього і доте...
Article
BacKground: ankylosing spondylitis (as) is characterized by diurnal variability of clinical symptoms, including aggravation of back pain at night and morning stiffness. Brain-derived neurotrophic factor (BdnF) is involved in the mechanisms of pain and circadian regulation. BDNF production may vary in the case of underlying fibromyalgia (FM), which...
Article
Full-text available
Vitamin D deficiency has been recognized as a pandemic with many negative health consequences in many countries. Today the mechanisms of anti-inflammatory and hepatoprotective action of vitamin D3 (cholecalciferol) and in general the scientific justification for its effective use in the clinic of type-2 diabetes (T2D) is actively studied in the sci...
Article
Full-text available
Pain in the lower abdomen and groin can occur in athletes who perform sharp lower extremity movement during training or sports, make sharp turns and change direction of the trunk movement as well as lower extremity acceleration/deceleration. An excessive load during the sports game can disturb the biomechanics of the player's movements. A precise l...
Article
Full-text available
Заняття спортом на аматорському чи професійному рівні може супроводжу-ватися виникненням тієї чи іншої спортивної травми. Однією із найбільш поширених травм у футболістів є травматизація анатомічних структур передньої черевної стінки та пахвинної ділянки, яка, зазвичай, проявляється больовим синдромом. Біль може виникати у спортсменів, які на трену...
Article
Full-text available
The nervous system is important in the mechanisms of the body’s response to exogenous factors, takes an active part in the mobilization of the body’s defenses to counteract adverse factors, traumatic injuries of various etiologies and more. The aim of our study was to study the ultrastructural changes in the hemocapillaries of the cerebral hemisphe...
Preprint
Poltava 2020 3 UDC 616.714:612 "Recommended by the Academic Council of the Ukrainian Medical Stomatological Academy as a study guide for foreign students receiving higher master's degrees, studying in the specialties 221"Stomatology", 222" Medicine "in higher educational institutions of of the Ministry of Health of Ukraine." Minutes of the meeting...
Article
Full-text available
Nowadays, the subject of research is to study the characteristics of the impact of the usage of immersive tech-nologies on the quality of the educational process. Using the equipment of the virtual reality rooms of the Educational and Research Center "Institute of Biology and Medicine" of Taras Shevchenko National University of Kyiv to implement im...
Article
Full-text available
Objective: The aim: Studying changes in the ultrastructure of blood circulatory capillaries of the myocardium of mature rats with hypothyroidism and arterial hypertension. Patients and methods: Materials and methods: Experiments were conducted on (240 days) 10 ISIAH (inherited stress-induced arterial hypertension) line rats with AH (arterial hyp...
Article
Full-text available
The aim: Study of the patterns of structural changes in the left ventricular myocardial capillaries of rats with arterial hypertension with combined pharmacotherapy with Bisoprolol and Thiotriazolinum. Materials and methods: Experiments were conducted on 30 line rats with congenital stress-induced arterial hypertension: 10 animals without treatment...
Article
Background Numerous non-drug therapies have emerged in recent years for the prevention and improvement of type 2 diabetes (T2D). However, therapies based on dietary modification and/or microbiota may replace a large part of drug therapies in the coming years. The current study aim was to conduct placebo-controlled randomize clinical trial for the e...
Article
Objective: The aim: Was to clarify the general patterns of structural changes in the left ventricular myocardial capillaries in rats with spontaneous arterial hypertension. Patients and methods: Materials and methods: Experiments were conducted on 50 ISIAH (inherited stress-induced arterial hypertension) line rats with arterial hypertension: juv...
Article
Full-text available
Objective: The aim: Was to compare the changes in hematological parameters of blood in the conditions of prolonged exposure of lead sulfide nanoparticles (NP) of different sizes and of lead nitrate. Patients and methods: Materials and methods: The study was conducted on mature male Wistar rats 160-180 g, intraperitoneally injected with Pb(NO3)2...
Article
Full-text available
Long-term administration of yellow tartrazine (E102) stain to sexually mature white rats at doses of 750 mg/kg and 1500 mg/kg is accompanied by a significant dosedependent disorder in the chemical composition of bones, namely, it leads to a significant decrease in the content of organic and mineral substances, an increase in the number of hydrophil...
Article
Full-text available
Background In recent years, the great attention of the scientific community has been drawn to the study of the role of homocysteine in the pathology of diseases in general and the respiratory system in particular. Violations of the synthesis and disposal of homocysteine become the cause of its excessive accumulation in the body, which subsequently...
Article
Objective: Introduction: In the treatment of hypothyroidism substitution therapy with L-thyroxine is used, it is also advisable to use the metabolites with membrane-stabilizing properties that normalize the metabolism in the body, for example, calcitonin, which significantly reduces the depth of the dystrophic phenomena in the myocardium. The aim...
Article
Full-text available
Background: The aim of this study was to obtain the first national estimates of the current prevalence and incidence and death of health care-associated infections (HAIs) of all types in acute care hospitals in Ukraine. Methods: Prospective surveillance was conducted from January 2014 to December 2016 in 17 hospitals. Surveillance case definitio...
Article
The histomorphometric study of proximal epiphyseal cartilage was performed on albino male rats in the reproductive period of ontogenesis. Animals received tartrazine dye (E102) in two doses of 750 mg/kg and 1500 mg/kg daily for 60 days. Prolonged administration of E102 is associated with decrease in the bone formation function of the cartilage. Aft...
Article
Full-text available
Introduction: The present investigation aims to elucidate the effects of Z56822977 on biosynthesis of serotonin in the brain of rats in the conditions of monosodium glutamate (MSG)-induced obesity. Material and methods: Eighteen male rats were used in the present study and divided into three groups: 1 - control group, 2 - MSG group, 3 - MSG + Z5682...
Article
Full-text available
Background. The article presents structural changes of the renal medulla in experimental traumatic skin injury in rats under conditions of intravenous infusion of a colloid-hyperosmolar solution of gekoton. It was found that gekoton acts on the structure of the body as a cytoprotector. Objective. To study structural changes of the renal medulla in...
Article
Full-text available
Epidemiological data showed that the number of obese people increases swiftly in all countries. Obesity can evoke metabolic syndrome or second type diabetes (T2D). So, the aim of our study was to investigate the influence of 2-[4-(benzyloxy) phenoxy] acetic acid on metabolic parameters of monosodium glutamate (MSG)-induced obesity in rats. We divid...
Article
Lead as any heavy metals may be found in soil, water, air, and is used in everyday life. Once in the body, it causes toxic effect, making the liver, which is one of the main organs of detoxification, suffer. Recently, the study of the action of not only ionic forms of lead, but also its nanoparticles, has become topical. The study aims at determini...
Article
Full-text available
p>У статті проведений аналіз лекції з анатомії людини з позицій її дидактичних функцій, формування кінцевої мети, якісної підготовки матеріалів до лекційних навчальних занять і структурування лекційного матеріалу відповідно до сучасних психолого-педагогічних вимог. </iframe
Article
p>З огляду на значний прогрес у розвитку медицини за сучасних інтенсивних соціально-економічних змін, необхідність у формуванні професійно орієнтованих знань лікарів різного профілю, підвищення вимог до професійних навичок фахівців є очевидною необхідність оптимізації існуючих і розробка нових методів та засобів навчання. Застосування в навчанні ін...
Article
Full-text available
The article describes the ultrastructural changes of adenohypophysis in experimental burn. The dynamics of microcirculation changes and the consequences of its violation also discovered. Between 1-14 daysafter the burn we observed of blood stasis, at 21-30 day observed recovery microcirculation and endocrine cells.Hyperosmolar infusion solutions en...
Patent
Full-text available
The use of lactoprotein with sorbitol as a marker indicating the changes in permeability of the blood capillaries in burn disease.
Article
Full-text available
Mechanisms of structural transformation of histohemic barriers of organs of the neuroimunuodocrine system under conditions of infusion therapy for burn disease
Article
Full-text available
В статті представлені результати досліджень рівня ендогенної інтоксикації у щурів протягом місяця після опіку шкіри ІІ-ІІІ ступеня, площею 21-23% поверхні тіла та її корекції інфузійними розчинами Лактопротеїну з сорбітолом та HAES-LX-5%, а також вплив досліджуваних препаратів на організм без моделювання патологічного стану. Встановлені суттєво...
Article
Full-text available
As a consequence of nascent technology, the 19th century witnessed a profound change in orientation to the nervous system. For example, improved microscopy in the first half of the 19th century allowed high magnification without blurring. The subsequent observation of nucleated cells led to the identification of individual brain cells. Philosophica...
Book
Перелік латинських, українських, російських та англійських еквівалентів анатомічних термінів новітніх латино-англійської (Stuttgart - New York, 1998), української (Київ, 2001) та російської (Москва, 2003) анатомічних номенклатур. Для лікарів, викладачів та науковців різних спеціальностей, редакційних працівників, студентів.

Network

Cited By

Projects

Projects (6)
Project
https://morphology-journal.com/index.php/journal