Olamide Adebiyi

Olamide Adebiyi
University of Ibadan · Department of Veterinary Physiology and Biochemistry

DVM, PhD
Optogenetic stimulation for enhancing cognition in multiple sclerosis

About

25
Publications
4,855
Reads
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291
Citations
Introduction
Olamide Adebiyi currently works at the Department of Veterinary Physiology and Biochemistry, University of Ibadan. Olamide does research in Veterinary Medicine, Neuroscience and Physiology. Their current project is 'Neuroprotection potentials of Grewia carpinifolia'.
Additional affiliations
January 2022 - January 2024
Western University London Ontario
Position
  • PostDoc
January 2019 - October 2019
Cornell University
Position
  • Visiting Fulbright Researcher
May 2015 - December 2015
State Key Laboratory of Phytochemistry and Plant Resources, Kunming, China
Position
  • PhD Student

Publications

Publications (25)
Article
Full-text available
Cadmium is a highly neurotoxic heavy metal that interferes with DNA repair mechanisms via generation of reactive oxygen species. The potentials of polyphenols and antioxidants as effective protective agents following heavy metal-induced neurotoxicity are emerging. We therefore explored the neuroprotective potentials of gallic and ascorbic acids in...
Article
Adverse effects of changing climate have been associated with increase average global temperature resulting in environmental changes. We set out to investigate effects of environmental stress due to increased heat exposure on developmental milestones, behaviour, gut microbiota and neuroarchitecture in rat pups. Pregnant Wistar rats were held in sta...
Article
Full-text available
Introduction: Erythrophleum Ivorense (EI) is a tree found across tropical Africa. The bark of EI is widely used as hunting poisons for animals and ordeal poison in humans. Eating this plant causes paralysis, respiratory distress, and amnesia. In folklore, these behavioral changes have been attributed to guilt in victims; nonetheless, no scientific...
Article
Trypanosoma brucei brucei causes animal trypanosomiasis in several vertebrates and human African trypanosomiasis. Previous studies have only explored the incidence, clinical symptoms, haematology and biochemical changes associated with the disease. The behavioral manipulation hypothesis posits that parasites alter the behavior of host to increase t...
Article
Full-text available
The straw-coloured fruit bats (Eidolon helvum) are the most widely distributed megachiropteran species in Africa. Studies have shown that they migrate, and are likely exposed to environmental pollutants across population. This study was designed to investigate genotoxicity via the bone marrow micronucleus assay and haematological alterations of Eid...
Article
Cobalt-induced cardiomyopathy and renal toxicity have been reported in workers in processing plants, hard metal industries, diamond polishing and manufacture of ceramics. This study was designed to investigate the influence of Luteolin supplementation on cobalt-induced cardiac and renal toxicity in rats. Exposure of rats to cobalt chloride (CoCl2)...
Article
Full-text available
Adult neurogenesis is a process where new neurons are generated postnatally from neural stem cells maintained till adulthood. These neural stem cells are maintained in the hippocampus and the olfactory bulb although recent evidence has established their presence in other regions of the brain. Adult neurogenesis was first thought to be impossible du...
Article
Ethnopharmacological relevance: Erythrophleum ivorense (A Chev.) is a common plant in the tropics. Its use as ordeal poison in folklore medicine is controversial. The incoordination and behavioral changes following consumption are often associated with guilt. This study is aimed at dispelling or upholding this belief by investigating the actions o...
Article
Fluoride is an environmental contaminant that is ubiquitously present in air, water, and soil. It is commonly added in minute quantity to drinking water, toothpaste, and mouth rinses to prevent tooth decay. Epidemiological findings have demonstrated that exposure to fluoride induced neurodevelopmental toxicity, developmental neurotoxicity, and moto...
Article
Full-text available
Background Eucalyptus oil (EO), derived from Eucalyptus species, possesses vast remedial and healing properties, although its gut health-promoting properties have not been well investigated. In this study, we investigated the chemical composition of a commercial EO formulation and its potential role in protecting against aflatoxin B1 (AfB1)-induced...
Article
Environmental discharge of vanadium causes cognitive and behavioral impairments in humans and animals via production of reactive oxygen species leading to lipid peroxidation and alteration in antioxidant defence system. The current study was carried out to investigate the cognitive-enhancing ability of β-sitosterol in vanadium-induced neurotoxicity...
Article
Full-text available
Introduction Exposures to toxic levels of vanadium and soluble vanadium compounds cause behavioral impairments and neurodegeneration via free radical production. Consequently, natural antioxidant sources have been explored for effective and cheap remedy following toxicity. Grewia carpinifolia has been shown to improve behavioral impairments in vana...
Article
Full-text available
Background: Hematological parameters are vital diagnostic tools for understanding health dynamics of humans and animals. Franquet's fruit bat (Epomops franqueti) is host to several parasites such as protozoa, bacteria, viruses and mites. Yet, studies exploring the values of its blood components with interest for research or food purposes are scarc...
Article
Full-text available
Free radicals are reactive molecules involved in many physiological processes and have been associated with many diseases, such as cancer, arthritis and liver injury. As a result, there is need to explore substances with free radical scavenging and or antioxidant activity. The present study was designed to evaluate the free radical scavenging activ...
Article
Full-text available
Vanadium (V), a heavy metal, has been reported to induce central nervous system toxicity leading to various behavioural impairments. It is characterized by the production of reactive oxygen. The present study was designed to test the possibility of Grewia carpinifolia ethanolic extract in preventing behavioural alterations following acute vanadium...
Article
Full-text available
Background: Grewia carpinifolia is a plant commonly used in the tropics to manage various central nervous system (CNS) disorders. However, despite its widespread use no scientific work has been reported to validate these claims. Objectives: To evaluate the activity of G. carpinifolia as it affects behaviour using animal model. Methods: Twenty...
Article
Full-text available
The leaves and stem of Grewia carpinifolia were evaluated for their nutritional and anti-nutritional composition. The results showed that the leaves had significantly higher (p<0.05) crude protein (18.7+0.06%), crude fat (5.19+0.02%), ash (9.92+0.03%) and gross energy (3.32+0.01Kcal/g) than the stem having crude protein (6.90+0.03%), crude fat (1.0...
Article
Full-text available
Pentavalent vanadium (metavanadate salt) toxicity is a challenging environmental hazard that affects living organisms. Studies have shown that plants play important roles in protecting against heavy metal toxicity. This study was designed to evaluate the protective activity of ethanolic extracts of Grewia carpinifolia leaves following vanadium toxi...
Article
Full-text available
This present study was carried out to investigate the haematological values of Rottweilers in a tropical environment with respect to sex, age, and breed. There were no significant (p > 0.05) breed-related differences in the values of red blood cell counts (RBC), packed cell volume (PCV), haemoglobin (Hb) concentration, mean corpuscular haemoglobin...
Article
Full-text available
The study was designed to evaluate the hepatoprotective activity of different solvent extracts (hexane, chloroform, ethyl acetate and methanol) of Enantia chlorantha stem bark in acute experimental liver injury induced by acetaminophen. The effects observed were compared with a known hepatoprotective agent, silymarin (100 mg/kg p.o.). Preliminary p...
Article
Full-text available
It is presumed that drugs sourced from herbs have lesser side effects than allopathic drugs. Enantia chlorantha is widely used in herbal medicine for the treatment of several ailments such as jaundice, malaria, fever, infective hepatitis, etc. However its toxicity profiles are not well documented. The effects of ethanolic extract of E. chlorantha s...
Article
Full-text available
Abstract Recent advances have witnessed the emergence of an increasing number of novel carriers for the delivery of drugs. In this manuscript, we review and discuss the blood cellular carriers because of their great biocompatibility and thus a reduction in side effects. Our emphasis was on the erythrocyte because recent studies have indicated that...

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Projects

Projects (3)
Project
Evaluation of effects of environmental chemicals, xenobiotics and other interventions on gut epithelium and microbiome integrity, including effects on gut-associated remote organs (liver, brain, kidneys, heart). The modulatory effects of dietary, pharmacological and natural products on identified alterations are important goals of this project
Project
Understanding The Biology and Anatomy of African Fruit Bats for their Conservation and pivotal role in maintaining nature and host to viral diseases that may be potential cause of cancer