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Introduction
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Publications
Publications (23)
Objective
This study aimed to determine whether routine third-trimester ultrasounds in low-risk pregnancies decrease the rate of perinatal death compared with regular antenatal care with serial fundal height measurements.
Data Sources
This was a systematic review and meta-analysis of randomized control trials to identify relevant studies published...
Objective:
To evaluate whether serial ultrasound examinations in the third trimester increase identification of a composite of growth or amniotic fluid abnormalities when compared with routine care among pregnancies that are uncomplicated between 24 0/7 and 30 6/7 weeks of gestation.
Methods:
Women without complications between 24 0/7 and 30 6/7...
Objective The objective of this study was to compare adverse pregnancy outcomes between fetuses with estimated fetal weight (EFW) < 10 to > 10% in women with preterm preeclampsia (PE) with severe features.
Materials and Methods All women with preterm PE with severe features and nonanomalous singletons with EFW were identified at a tertiary center....
Objective:
To estimate whether nonsteroidal antiinflammatory drugs (NSAIDs) are associated with persistent postpartum hypertension in a cohort of women with preeclampsia and severe features.
Methods:
We conducted a retrospective cohort study at a single, tertiary center from January 2013 to December 2015. All women diagnosed with severe preeclam...
Objective observations of the uncommon occurrences can be gratifying, albeit grating. The gratifying part of the case series from Netherlands on severe preeclampsia before 26 weeks is undeniable. To convince all tertiary centres in a country to collect data on an obstetric phenomenon which occurs in 0.013% (133/1,044,287) of deliveries is an accomp...
Preeclampsia with severe features (SPE) remote from term remains a major cause of maternal morbidity and mortality worldwide. With increasing diagnosis of SPE remote from term and improved methods for monitoring maternal and fetal well-being, several challenges have been made regarding management of preeclampsia. We reviewed the scientific literatu...
Introduction:
Hypertensive disorders have become increasingly prevalent and complicate an increasing number of pregnancies. Therefore it is essential that the medications used to treat these disorders be well understood. Furthermore the management is complicated by special consideration needed for the physiologic changes of pregnancy as well as th...
Despite intensive research, the pathogenesis of PE remains a mystery. Our study demonstrates a novel interaction between C-reactive protein (CRP) and Neurokinin B (NKB) leading to enhanced activation of the Neurokinin 3 receptor (NK3R).
Patient sera and placental tissue were obtained from Memorial Hermann Hospital, Houston, TX. CRP and NKB levels w...
C-reactive protein (CRP), an innate immune mediator, is elevated in the circulation before symptoms in patients with preeclampsia, a severe hypertensive pregnancy disorder with high mortality and morbidity. However, the specific sources underlying increased CRP and the role of elevated CRP in preeclampsia are undefined. Here, we report that circula...
