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Ogochukwu Augustina Meko

Ogochukwu Augustina Meko

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9
Publications
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17
Citations

Publications

Publications (9)
Article
Full-text available
Extraction parameters are important in determining the physicochemical properties of extracts. This work aimed to investigate the effect of extraction parameters on the physicochemical properties of keratin powder obtained from chicken feather wastes. Keratin was extracted using alkaline hydrolysis under different experimental conditions viz: conce...
Preprint
Full-text available
The knowledge on the extraction parameters is an important aspect for researchers in converting feathers waste to resourceful keratin. This work aims at investigating the effect of extraction parameters on the yield of keratin obtained from waste chicken feathers as well as carrying out some characterization of the extracted keratin. Keratin was ex...
Article
Full-text available
Background: The study aimed to evaluate the effect of arachis oil and liquid paraffin on metoclopramide release from transdermal films. Objectives: Batches of metoclopramide films were prepared with hydroxypropyl methyl cellulose (HPMC), arachis oil or liquid paraffin and Tween 80 as plasticizer. The films were evaluated for their physiochemical pr...
Article
Full-text available
The study investigated the effects of eucalyptus oil and shea butter on the physicochemical and bioadhesion properties as well as on the ex vivo drug release of metoclopramide from transdermal patch. Metoclopramide patches were formulated using hydroxypropyl methylcellulose (HPMC) in combination with varied proportions of shea butter and eucalyptus...
Article
Full-text available
The physicochemical properties of excipients play vital roles in the process of tablet manufacture. A comparative evaluation of the binding and disintegrant properties of xerogels of cassava and cocoyam starches with microcrystalline cellulose (MCC) in paracetamol tablet formulations was investigated. Cassava and cocoyam starches were extracted fro...
Article
Full-text available
Purpose: To investigate the binding properties of the modified (acid treated) millet (Pennisetum glaucum) starch mucilage in comparison with maize starch BP on some physical characteristics of paracetamol tablets. Method: Pennisetum glaucumstarch was extracted and subjected to acid modification. Mucilages of the modified starch and maize starch BP...
Article
Full-text available
The aim of the study was to develop a novel co-processed excipient for direct compression and fast disintegration of tablets. The novel excipients were prepared by co-processing hydroxypropyl methylcellulose (HPMC) at varying concentrations with croscarmellose sodium, dicalcium phosphate, magnesium stearate and talc. Their slurry was homogenized, d...
Article
Full-text available
The aim of the study was to investigate the properties of microcrystalline cellulose (MCC) obtained from cassava stems using the nitric acid and sodium hydroxide methods of extraction in comparison with Avicel® PH 101 in metronidazole tablet formulations. Alpha-cellulose from cassava stems was extracted with nitric acid and sodium hydroxide methods...

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