Ognjen Barcot

Klinički Bolnički Centar Split | KBC Split · Department of surgery

Background The potential benefit of neoadjuvant chemotherapy (NAC) in colon cancer is under evaluation. There is a need to improve preoperative non-invasive diagnostics using techniques that provide more accurate staging information in assessing patient eligibility for NAC. Purpose To investigate the link between the tumor grade (pathohistological...

Several scoring systems exist for the management of acute appendicitis (AA) during pregnancy. However, the systems are based on the nonpregnant adult population. The aim of this study was to create a highly accurate scoring system that can be applied to pregnant women and to compare it to the most commonly used scores in general population and preg...

COVID-19 prediction models mostly consist of combined clinical features, laboratory parameters, and, less often, chest X-ray (CXR) findings. Our main goal was to propose a prediction model involving imaging methods, specifically ultrasound. This was a single-center, retrospective cohort observational study of patients admitted to the University Hos...

Background: Lung ultrasound (LUS) is a useful imaging method for identifying COVID-19 pneumonia. The aim of this study was to explore the role of LUS in predicting the severity of the disease and fatality in patients with COVID-19. Methods: This was a single-center, follow-up study, conducted from 1 November 2020, to 22 March 2021. The LUS proto...

Background Initially, the Cochrane risk of bias (RoB) tool had a domain for “blinding of participants, personnel and outcome assessors”. In the 2011 tool, the assessment of blinding was split into two domains: blinding of participants and personnel (performance bias) and blinding of outcome assessors (detection bias). The aims of this study were tw...

Objective This randomized controlled trial (RCT) aimed to test the efficacy of enhanced access to Cochrane Handbook (Handbook) recommendations for judging the 2011 Cochrane risk of bias (RoB) domains for improving the adequacy of RoB judgments. Study Design and Setting Parallel-group RCT with a 1:1 allocation ratio (N = 2271 per group) was conduct...

Background Radical dissection of lymph nodes, accompanying gastric cancer resection, can lead to collateral damage to the pancreas and development of postoperative pancreatic fistula (POPF). Methods We searched the Cochrane Library, MEDLINE, Embase, and Web of Science up to April 21, 2020, to identify studies documenting the value of abdominal dra...

Objectives Our study aimed to explore the discrepancy of results between overlapping systematic reviews (SRs) of laparoscopic appendectomy (LA) versus open appendectomy (OA) for suspected appendicitis during pregnancy.MethodsMEDLINE, Embase, and Cochrane Database of Systematic Reviews (CDSR) were searched for SRs published from January 1, 2017 to S...

Abstract Background Bias in randomized controlled trials (RCTs) can lead to underestimation or overestimation of the true effects of interventions. Surgical RCTs may suffer from the risk of bias (RoB) that is avoidable in trials of other interventions, and vice versa. We aimed to compare the adequacy of RoB assessments in surgical versus non-surgic...

Aim: Adequate judging of risk of bias (RoB) for blinding of outcome assessors (detection bias) is important for supporting highest level of evidence. Materials & methods: Judgments and supporting comments for detection bias were retrieved from RoB tables reported in Cochrane reviews. We categorized comments, and then compared judgment and supportin...

Objective To analyze how many non-Cochrane systematic reviews (NCSRs) used Cochrane’s risk of bias (RoB) tool, domains they used, and whether judgments and comments about risk of bias were in line with Cochrane Handbook. Methods This was a methodological (research-on-research) study. We retrieved NCSRs from PubMed, extracted information about meth...

Objective: To measure the level of agreement between Cochrane Reviews of overlapping randomized controlled trials (RCTs) regarding risk-of-bias (RoB) judgments. Study design and setting: On November 5, 2017, the Cochrane Database of Systematic Reviews was searched for Cochrane reviews on tobacco. Reviews that included overlapping RCTs were inclu...

Background: Assessing the risk of bias (RoB) in included studies is one of the key methodological aspects of systematic reviews. Cochrane systematic reviews appraise RoB of randomised controlled trials (RCTs) with the Cochrane RoB tool. Detailed instructions for using the Cochrane RoB tool are provided in the Cochrane Handbook for Systematic Revie...

Objectives: The objective of this study was to analyze adequacy of judgments about risk of bias (RoB) for blinding of participants and personnel (performance bias) in Cochrane systematic reviews of randomized controlled trials (RCTs). Study design and setting: We extracted judgments and supporting comments for performance bias from Cochrane revi...

Objectives: The aim of the study was to analyze adequacy of risk of bias (RoB) judgments for selective reporting in Cochrane systematic reviews. Study design and setting: We extracted RoB assessments, including judgment (low, high, or unclear risk) and supporting comment from Cochrane reviews of randomized controlled trials using computer parser...

Objectives: The aim of the article was to analyze whether the risk of bias (RoB) judgments for allocation concealment in Cochrane systematic reviews (CSRs) were in line with recommendations from the Cochrane Handbook. Study design and setting: From CSR, we extracted data about judgments and supporting comments about allocation concealment for ea...

Background: Purpose of this study was to analyze adequacy of judgments about risk of bias (RoB) for random sequence generation in Cochrane systematic reviews (CSRs) of randomized controlled trials (RCTs). Methods: Information was extracted from RoB tables of CSRs using automated data scraping. We categorized all comments provided as supports for ju...

Fourier transform infrared (FT-IR) spectra of human spermatozoa and seminal plasma were recorded and analyzed. The procedure that was established for sample preparation enabled acquisition of reproducible spectra. The parameter I(1087)/I(966) for controlling spectra reproducibility was defined. The assignment of bands was carried out using an empir...