Odianosen Ehiakhamen

• MBBS, MPH
• Nigeria center for disease control

Introduction: Limited studies describe the epidemiology, clinical presentation, and outcome of mpox in Rivers State, Nigeria. Methods: an observational retrospective study of suspected mpox cases seen between October 21, 2021, and April 30, 2023, at the University of Port Harcourt Teaching Hospital, Rivers State, Nigeria. Laboratory confirmation w...

Summary box Countries in Africa are grappling with an ongoing multi-country outbreak of the Mpox virus. Despite the longstanding presence, there are significant limitations, including restricted access to medical countermeasures such as diagnostics, therapeutics and vaccines. This commentary examines three forms of ‘violence’ driving the Mpox outb...

While large language models (LLMs) have shown promise for medical question answering, there is limited work focused on tropical and infectious disease-specific exploration. We build on an opensource tropical and infectious diseases (TRINDs) dataset, expanding it to include demographic and semantic clinical and consumer augmentations yielding 11000+...

Both Nigeria and Cameroon reported their first mpox cases in over 30 years in 2017 and 2018 respectively. The Nigerian outbreak is recognised as an ongoing human epidemic. However, owing to sparse genomic data, it is not known whether the increase in cases in Cameroon is driven by zoonotic transmission, or whether the mpox virus (MPXV) is spreading...

Nigeria and Cameroon reported their first mpox cases in over three decades in 2017 and 2018 respectively. The outbreak in Nigeria is recognised as an ongoing human epidemic. However, owing to sparse surveillance and genomic data, it is not known whether the increase in cases in Cameroon is driven by zoonotic or sustained human transmission. Notably...

Five years before the 2022 global mpox outbreak Nigeria reported its first cases in nearly 40 years, with the ongoing epidemic since driven by sustained human-to-human transmission. However, limited genomic data has left questions about the timing and origin of the mpox virus (MPXV) emergence. Here we generated 112 MPXV genomes from Nigeria from 20...

Background We describe diverse clinical characteristics and course of confirmed Mpox cases managed in a Nigerian tertiary health facility. Method Clinical and epidemiological data were analyzed highlighting the unusual presentations of PCR confirmed Mpox cases observed during 2022 outbreak. Result Out of 17 suspected cases, 13(76.4%) were PCR con...

Introduction We describe clinico-epidemiologic characteristics of mpox∕chickenpox co-infection in Nigeria. Methodology A retrospective cohort analysis of confirmed mpox cases in Nigeria from January 2022 to March 2023. Mpox and chickenpox were confirmed by RT-PCR. Results 56/94 (60.0%) suspected cases had confirmed mpox of whom 16 (28.6%) had chi...

Monkeypox (MPX) is a viral zoonosis with lesions like smallpox. Though rare in Nigeria, sporadic outbreaks have been reported in 17 states since September 2017. Unfortunately, the COVID-19 pandemic has further reduced surveillance and reporting of MPX disease. This study seeks to assess the effect of an enhanced surveillance approach to detect MPX...

Monkeypox (MPX) is a viral zoonosis with lesions like smallpox. Though rare in Nigeria, sporadic outbreaks have been reported in 17 states since September 2017. Unfortunately, the COVID-19 pandemic has further reduced surveillance and reporting of MPX disease. This study seeks to assess the effect of an enhanced surveillance approach to detect MPX...