O. Kgosidialwa

O. Kgosidialwa
Royal College of Physicians of Ireland | RCPI

About

23
Publications
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101
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Publications

Publications (23)
Preprint
Objectives: The aim of this study is to examine alanine aminotransferase (ALT) levels in a cohort of women diagnosed with gestational diabetes mellitus (GDM) and to investigate the association between elevated ALT and pregnancy outcomes. Design: A retrospective cross-sectional study. Setting: Cork University Maternity Hospital Population: Women att...
Article
Full-text available
Aim Report the outcomes of pregnant women with type 1 and type 2 diabetes and to identify modifiable and non-modifiable factors associated with poor outcomes. Methods Retrospective analysis of pregnancy preparedness, pregnancy care and outcomes in the Republic of Ireland from 2015-2020 and subsequent multivariate analysis. Results In total 1104 p...
Article
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Background Fine needle aspiration (FNA) cytology is the preferred method for assessing thyroid nodules for malignancy. Concern remains about the rate of false negative results. The primary aim of this study is to investigate the malignancy rate of thyroid nodules initially classified as benign (Thy 2). Methods We retrospectively examined 658 nodu...
Article
Background: Adoption of the International Association of Diabetes and Pregnancy Study Group (IADPSG) criteria for diagnosis of gestational diabetes mellitus (GDM) varies worldwide. Early detection of women at increased risk of developing type 2 diabetes mellitus (T2DM) following GDM enables initiation of measures to delay disease onset. Objective...
Article
Aims Patient-reported outcomes (PROs) are reports of the patient’s health status that come directly from the patient without interpretation by the clinician or anyone else. They are increasingly used in randomised controlled trials (RCTs). In this systematic review we identified RCTs conducted in women with diabetes in pregnancy which included PROs...
Article
Aims To update and extend a previous cross-sectional international comparison of glycaemic control in people with type 1 diabetes. Methods Data were obtained for 520,392 children and adults with type 1 diabetes from 17 population and five clinic-based data sources in countries or regions between 2016 and 2020. Median HbA1c(IQR) and proportions of...
Article
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Background: Pregestational diabetes mellitus (PGDM) is associated with adverse pregnancy outcomes. Studies assessing interventions to improve maternal and infant outcomes have increased exponentially over the last number of years. Several outcomes in this field of maternal diabetes are rare outcomes making it difficult to synthesize evidence. Obj...
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Introduction Diabetes mellitus is the most common metabolic complication of pregnancy and its prevalence worldwide is rising. The number of randomised controlled trials (RCTs) being conducted in people with diabetes is also increasing. Many studies preferentially publish findings on clinical endpoints and do not report patient-reported outcomes (PR...
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Objective: To develop a core outcome set (COS) for randomised controlled trials (RCTs) evaluating the effectiveness of interventions for the treatment of pregnant women with pregestational diabetes mellitus (PGDM). Design: A consensus developmental study. Setting: International. Population: Two hundred and five stakeholders completed the fir...
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Background Pregestational diabetes mellitus (PGDM) is associated with adverse pregnancy outcomes including increased rates of caesarean section birth, macrosomia, congenital malformation, prematurity, admission to the neonatal intensive care unit and stillbirth. As a result, there has been an increase in interventions to improve outcomes in both mo...
Article
Core Outcome Sets (COS) contain an agreed minimum set of outcomes to be measured and reported in all studies in a specific area, with the objective of standardizing outcome reporting. COS may minimize research waste by identifying outcomes important to key stakeholders, allowing for improved evidence synthesis, and facilitating translation of resea...
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Aims/hypothesis: The aim of this systematic review was to develop core outcome sets (COSs) for trials evaluating interventions for the prevention or treatment of gestational diabetes mellitus (GDM). Methods: We identified previously reported outcomes through a systematic review of the literature. These outcomes were presented to key stakeholders...
Article
Background The incidence of post-transplant diabetes (PTDM) is variable primarily due to a lack of standardised diagnostic criteria. Aim This study aimed to assess the incidence of PTDM in heart and lung transplant (HLT) patients and to review if the management of these patients is in accordance with the 2014 American Society of Transplantation gu...
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Traumatic brain injury (TBI) is fairly common and annually affects millions of people worldwide. Post traumatic hypopituitarism (PTHP) has been increasingly recognized as an important and prevalent clinical entity. Growth hormone deficiency (GHD) is the most common pituitary hormone deficit in long-term survivors of TBI. The pathophysiology of GHD...
Article
Post-traumatic hypopituitarism (PTHP) is an important and relatively common complication of TBI (traumatic brain injury). A number of studies have shown that this clinical phenomenon can occur soon after TBI (acute) or later in the chronic phase. Patients with moderate to severe TBI are at a particular risk of developing PTHP. In the acute setting,...
Article
Context: Prevalence of gestational diabetes mellitus (GDM) and obesity continue to increase. Objective: To ascertain if diet and exercise is a successful intervention for women with GDM and if a subset of these women have comparable outcomes to those with normal glucose tolerance (NGT). Design: A retrospective cohort study. Setting: Five ant...

Projects

Project (1)