Nuradilla Mohamad-Fauzi

University of Malaya | UM · Institute of Biological Sciences

Mature coconut water (MCW) has been demonstrated to contain bioactive compounds with antioxidant properties. In vivo research showed that MCW supplementation increased semen quality in rats, suggesting that it may boost reproductive performance. This study investigated the impact of MCW on the reproduction of Boer bucks. Two groups of 12 sexually m...

Polar micro-fungi are known to have developed protective mechanisms and responses against the harmful effects of UV radiation. In this study, physiological, cellular, and transcriptomic responses of an Arctic fungal strain of Pseudogymnoascus australis towards UV-B radiation were examined. Fungal isolate was cultured on 0.45μm nylon membranes overl...

The clownfish-sea anemones are a diverse group of benthic anthozoans that are foundpredominantly in tropical to subtropical waters. However, little is known about their adaptation to changes in their environment. Here, we investigated the effects of high light (HL) and low light (LL) on the Symbiodiniaceae in Radianthus magnifica (n = 8) in depths...

Sheep are an important source of protein for humans, and recent decades have seen a significant increase in the production of sheep-based products, thus indicating an increase in demand for this commodity. At a time when this sector is growing, sheep are exposed to various challenges. These include climate change, which can cause heat stress in she...

The potential of mesenchymal stem cells (MSCs) for tissue repair and regeneration has garnered great attention. While MSCs are likely to interact with microbes at sites of tissue damage and inflammation, like in the gastrointestinal system, the consequences of pathogenic association on MSC activities have yet to be elucidated. This study investigat...

Solar radiation regulates most biological activities on Earth. Prolonged exposure to solar UV radiation can cause deleterious effects by inducing two major types of DNA damage, namely cyclobutane pyrimidine dimers (CPDs) and pyrimidine 6‐4 pyrimidone photoproducts (6‐4PPs). These lesions may be repaired by the photoreactivation (Phr) and nucleotide...

Mesenchymal stem cells (MSCs) have great value as therapeutic tools in a wide array of applications in regenerative medicine. The wide repertoire of cell functions regarding tissue regeneration, immunomodulation, and antimicrobial activity makes MSC-based therapy a strong candidate for treatment options in a variety of clinical conditions and shoul...

Over the last decade, food waste has been one of the major issues globally as it brings a negative impact on the environment and health. Rotting discharges methane, causing greenhouse effect and adverse health effects due to pathogenic microorganisms or toxic leachates that reach agricultural land and water system. As a solution, composting is impl...

The potential of mesenchymal stem cells (MSCs) for tissue repair and regeneration has garnered great attention. While MSC interaction with microbes at sites of tissue damage and inflammation is likely, especially in the gut, the consequences of bacterial association have yet to be elucidated. This study investigated the effect of Salmonella enteric...

Solar radiation regulates all biological activities on Earth. Prolonged exposure to UV radiation can cause deleterious effects to all organisms especially those inhabit in the polar regions during the summer. In this study, we compared the repair of UV-induced DNA damage under two repair conditions, light and dark, each of which induced the photore...

Fungi are microbes that play vital roles in nutrient cycling in the natural environment and in symbiotic interactions with plants and other microbes. They thrive successfully even when challenged by various abiotic and biotic stress factors in the natural environment. Their growth, conidia production, survival, germination, pathogenicity, virulence...

UV radiation on earth has been increasing since the ozone depletion event in 1980s. Solar UV radiation is essential for the living on Earth, affecting lives on Earth directly and indirectly. The increment of UV-B radiation following ozone depletion has impacted the organisms, especially microbes in soils negatively by inducing cellular damages, alt...

UV radiation on earth has been increasing since the ozone depletion event in 1980s. Solar UV radiation is essential for the living on Earth, affecting lives on Earth directly and indirectly. The increment of UV-B radiation following ozone depletion had impacted the organisms, especially microbes in soils negatively by inducing cellular damages, alt...

UV radiation on earth has been increasing since the ozone depletion event in 1980s. Solar UV radiation is essential for the living on Earth, affecting lives on Earth directly and indirectly. The increment of UV-B radiation following ozone depletion has impacted the organisms, especially microbes in soils negatively by inducing cellular damages, alt...

Solar UV radiation is the primary source of light energy on the Earth’s surfaces responsible for a wide range of biological effects in many organisms. Excessive exposure to solar radiation increases in the temperature, dehydration, and UV-induced damages in most organisms. A cosmopolitan genus of soil fungi, Pseudogymnoascus sp., often inhabits at...

The search for cold-adapted and cold-active fungi in extreme environments provides the potential for discovering new species and novel bioactive compounds. In this study, soil samples were collected from Deception Island, Wilhelmina Bay (north-west Antarctic Peninsula, Graham Land) and Yankee Bay (Greenwich Island), maritime Antarctica, for the iso...

Jambongan, Mandidarah and Malawali Islands in the Sulu Sea were chosen for studying marine manglicolous fungi in 2009. Driftwood, prop roots, pneumatophores, subterranean roots, rhizomes, overhanging branches and twigs of mangrove trees were examined for the presence of marine fungi. A total of 173 samples yielded 78 marine manglicolous taxa: 66 As...

There is considerable interest in using goats as models for genetically engineering dairy animals and also for using stem cells as therapeutics for bone and cartilage repair. Mesenchymal stem cells (MSCs) have been isolated and characterized from various species, but are poorly characterized in goats. Goat MSCs isolated from bone marrow (BM-MSCs) a...

Contents The presence of the zona pellucida has been perceived as a requirement for the oviductal transfer of cloned embryos at early stages of development while protecting the embryo from an immune system response. We hypothesized that steroid hormone therapy could reduce a potential cellular immune response after the transfer of zona‐free cloned...

The aim of this study was to compare the efficiency of goat cloning by using cell lineages from distinct transgenic backgrounds. Primary fibroblast skin cell cultures from 2 females (allogeneic), transgenic for the human lysozyme gene (hLZ), were established following standard procedures. Cells from one hLZ genotype were used for the establishment...

Survival to term following embryo transfer is usually low after cloning by somatic cell nuclear transfer (SCNT). The aims of this study were to evaluate the effects of the zona pellucida (presence or absence) and the cell nucleus transfer method (cell fusion or cell injection) on the in vitro survival and pregnancy outcome of Day-1 goat cloned embr...

Gene modification of cells in vitro followed by somatic cell nuclear transfer (SCNT) currently offers the best route for creating genetically modified livestock species. However, low cloning efficiencies in differentiated somatic cells have been attributed to the possibility of improper nuclear reprogramming. Adult stem cells may have greater devel...

The aim of this study was to compare the effect of 2 donor cell types (bone marrow-derived mesenchymal stem cells, BM-MSC and skin fibroblast cells, SFC) and the source of oocytes (in vivo- and in vitro-matured goat oocytes) on the developmental capacity of handmade cloned goat embryos, following our procedures adapted from cattle (Ribeiro et al.,...

Background: The current status of genetic engineering animals for biomedical and human health applications, including improving the supply of animal-based food products, was reviewed. Although transgenic animals have been available for almost 30 years only one product, a drug derived from transgenic goats' milk, has been approved for use anywhere i...