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Introduction
I am a postdoctoral research associate at Liverpool School of Tropical Medicine. My current research is to understand insecticide resistance by investigating insect P450 metabolism activity against insecticides. My research interests are in the field of plant molecular biology, biopesticides development, and chemical biology in plant hormonal signalling.
Current institution
Additional affiliations
July 2010 - February 2014
July 2014 - March 2018
Publications
Publications (8)
BACKGROUND
Spear®‐T sold as a contact foliar spray for the control of glasshouse pests such as aphids, thrips, spider mites and whiteflies, contains the recombinant spider venom peptide GS‐ω/κ‐HxTx‐Hv1h (named as GS‐ω/κ‐HxTx‐Hv1a by Vestaron) as the active ingredient. Here we investigate whether fusion of the peptide to snowdrop lectin, (Galanthus...
Synthesized small molecules are useful as tools to investigate hormonal signaling involved in plant growth and development. They are also important as agrochemicals to promote beneficial properties of crops in the field. We describe here the synthesis and mode of action of a novel growth‐promoting chemical, A1. A1 stimulates enhanced growth in both...
After an episode of heat stress plants retain a cellular “memory” of this event, a phenomenon known as thermomemory. This mechanism allows plants to better cope against a subsequent heat event. Thermomemory occurs through the persistence of heat shock proteins (HSPs) synthesized after the first “priming” event. Maintenance of this thermomemory come...
The nemertide toxins from the phylum Nemertea are a little researched family of neurotoxins with potential for development as biopesticides. Here we report the recombinant production of nemertide α-1 (α-1), a 65-residue inhibitor cystine knot (ICK) peptide from Lineus longissimus, known to target insect voltage-gated sodium channels. The insecticid...
Stomatal aperture is tightly regulated in order to achieve the best compromise between gas exchange and water conservation. Steady-state (basal) stomatal aperture is therefore understandably a key component in plant fitness. It has been shown previously in tomato that DELLA proteins act as positive regulators of closure of stomata, and their action...
Temperature is one of the key factors in limiting the distribution of plants and controlling major metabolic processes. A series of simulated reciprocal transplant experiments were performed to investigate the effect of temperature on plant chemical composition. Polygonum minus from different lowland and highland origins were grown under controlled...
Fourier transform infrared spectroscopy was used to characterise highland and lowland populations of Polygonum minus Huds. grown in different controlled environments. A thermal perturbation technique of two-dimensional correlation infrared spectroscopy (2D-IR) cor-relation spectra was applied to establish differences between the populations. The ab...
