Nora Abdullah ALFaris

Nora Abdullah ALFaris
Princess Nora bint Abdul Rahman University | PNU

PHD

About

70
Publications
25,725
Reads
How we measure 'reads'
A 'read' is counted each time someone views a publication summary (such as the title, abstract, and list of authors), clicks on a figure, or views or downloads the full-text. Learn more
651
Citations

Publications

Publications (70)
Article
Full-text available
Background/aim: As recommended by WHO, breastfeeding is the best choice and safe for infants. The formula for infants plays an imperative role in the infant's diet and remains an excellent alternative for breast milk. The milk formula for most infants has been increasingly changed with various compositions to create a similar breast milk productio...
Article
Full-text available
The present study examined the phytochemical composition , antioxidant, antimicrobial properties, and molecular docking of different solvents extracts (methanol, , and water) of two medicinal plants, namely, Capparis spinosa L (CS) and Rumex nervosus (RN). Phytochemical analysis showed that total phenol, flavonoids, alkaloids, and vitamin C were si...
Article
Full-text available
Objectives: This study was conducted to assess differences in the prevalence of overweight and obesity among young men from twelve Middle Eastern and Asian countries who live in Riyadh, Saudi Arabia. Methods: This study used a cross-sectional design and was conducted in Riyadh, Saudi Arabia. The body weight and height of 3600 young men (aged 20...
Article
Full-text available
Despite significant studies on the COVID-19 pandemic, scientists around the world are still battling to find a definitive therapy against the ongoing severe global health crisis. In this study, advanced computational approaches have been employed to identify bioactive food constituents as potential SARS-CoV-2 PLpro inhibitors-modulators. As a valid...
Article
This study tested the protective effect of Rumex nervous (R. nervosus) methanol extract against streptozotocin (STZ)-mediated type 1 diabetes mellitus (T1DM)-induced nephropathy in rats and examined if this protection involves activating the nuclear factor erythroid 2 related factor-2 (Nrf2). Rats were divided into control, R. nervous (300 mg), STZ...
Article
Full-text available
Purpose: This study was conducted to determine differences in overweight and obesity prevalence and the associated sociodemographic variables among middle-aged men from twelve Middle Eastern and Asian countries living in Riyadh, Saudi Arabia. Methods: This is a cross-sectional study. The study sample was chosen randomly using a stratified cluste...
Article
This study evaluated if miR-34a/SIRT1 signalling mediates the anti-hepatosteatotic effect of resveratrol (RSV) in high-fat-diet (HFD)-fed rats. Rats were divided into seven groups (n = 6/each) as control, control + miR-34a agomir negative control, HFD, HFD + miR-34a, HFD + RSV, HFD + RSV + Ex-527 (a SIRT1 inhibitor), and HFD + RSV + miR-34a agomir....
Article
Full-text available
Breakfast skipping is linked with obesity incidence. This study was conducted to assess the prevalence of breakfast skipping among a multi-ethnic population of young men residing in Saudi Arabia and its relationship with sociodemographic determinants and weight status. A total of 3600 young men aged 20 to 35 years and living in Riyadh, Saudi Arabia...
Article
Full-text available
Objectives: This study investigated physical activity levels and factors related to physical inactivity in a multi-ethnic population of middle-aged men living in Saudi Arabia. Methods: This is a cross-sectional study in which 1,800 men aged 36-59 years old from Riyadh, Saudi Arabia participated. The Global Physical Activity Questionnaire was used t...
Article
Full-text available
Background Breakfast eating is regarded to be necessary for maintaining a healthy body weight. On the other hand, breakfast skipping has been linked with obesity incidence. This study was carried out to determine the prevalence of breakfast skipping among a multi-ethnic group of middle-aged men living in Saudi Arabia and the association between bre...
Article
Full-text available
Objective: Regular physical activity is essential for lifelong optimal health. Contrarily, physical inactivity is linked with risk for many chronic diseases. This study was conducted to evaluate the physical activity levels and factors associated with physical inactivity among a multi-ethnic population of young men living in Saudi Arabia. Methods...
Article
Full-text available
This study examined if sirtuin-1 (SIRT1) signaling mediates the nephroprotective effect of kaempferol in doxorubicin (DOX)-treated rats. Rats were divided into control, kaempferol, DOX, kaempferol + DOX, and kaempferol + DOX + EX-527 (a SIRT1 inhibitor). Kaempferol preserved the kidney structure and function in DOX-treated rats by attenuating the i...
Article
Full-text available
As a part of our continued effort to isolate and identify the pharmacological properties of polyphenols from Malus Sikkimensis, here in this work we have evaluated the neuroprotective effect these polyphenols along with their antioxidant and antiplasmodial properties. The antioxidant potential of these bioactives was estimated using enzymatic and n...
Article
Full-text available
Abstract Wheat flour with high protein quality is utilized for a wide scope of heated items particularly bread because of the viscoelastic property of the wheat flour that exhibits both viscous and elastic characteristics when undergoing deformation. Wheat contains the gluten framing proteins that structure a viscoelastic. D-glucans is considered a...
Article
Full-text available
Context Ellagic acid (EA) is used in traditional medicine to treated hyperlipidaemia. Objective This study examined if AMPK mediates the anti-steatotic effect of ellagic acid (EA) in streptozotocin (STZ)-induced type 1 diabetes mellitus in rats. Materials and methods Adult male Wistar rats (130 ± 10 g) were divided into 6 groups (n = 8 rats/group...
Article
Full-text available
Context Kaempferol, a flavonoid glycoside, has many hepatoprotective effects in several animals due to its antioxidant potential. Objective This study evaluated the hepatoprotective effect of kaempferol against acetaminophen (APAP)-induced liver damage and examined whether the protection involved modulation of silent information regulator 1 (SIRT1...
Article
Full-text available
The current ongoing pandemic of COVID-19 urges immediate treatment measures for controlling the highly contagious SARS-CoV-2 infections. The papain-like protease (PLpro), which is released from nsp3, is presently being evaluated as a significant anti-viral drug target for COVID-19 therapy development. Particularly, PLpro is implicated in the cleava...
Article
Full-text available
In this study, a set of dietary polyphenols was comprehensively studied for the selective identification of the potential inhibitors/modulators for galectin-1. Galectin-1 is a potent prognostic indicator of tumor progression and a highly regarded therapeutic target for various pathological conditions. This indicator is composed of a highly conserve...
Article
Full-text available
Endoplasmic reticulum (ER) stress plays a key role in cadmium chloride (CdCl2)-induced nephrotoxicity. Sirtuin-1 (SIRT1) is a potent inhibitor of ER stress. In this study, we examined whether the protective effect of quercetin (QUR) against CdCl2-induced nephrotoxicity in rats involved modulation of SIRT1 and/or ER stress. Adult male rats were divi...
Article
Full-text available
Shrimp is a prevalent food in the Arabian Gulf that is known for its good sensory properties and high nutritional value. The aim of the present work was to assess the effects of diverse processing methods on the nutritional composition of shrimp and the antioxidant activity of shrimp powder. Shrimp (Penaeus semisulcatus) flesh was treated using fou...
Article
This study examined the protective effect of ellagic acid (EA) against streptozotocin (STZ)-induced hippocampal damage and memory loss and investigated some mechanisms of action. Adult male rats were divided into 4 groups (n = 12) as control, control + EA (50 mg/kg), STZ-DM, and STZ-DM + EA. Treatments were given orally and daily for 8 weeks. Memor...
Article
Full-text available
Ripe date fruits are a rich source of antioxidants. The current scoping review was conducted to identify various characteristics of studies that were carried out to determine antioxidant content in ripe date fruits. The framework established by Arksey and O’Malley was adopted to conduct this scoping review. The Preferred Reporting Items for Systema...
Article
Full-text available
Fish meats comprise an important part of diets; however, their rich nutrient composition and various sources mean these products can be spoiled quickly. The present study assessed the chemical and microbiological quality of imported chilled, frozen, and locally cultured fish in Saudi Arabian markets. Physiochemical, heavy metal, and microbial analy...
Article
Full-text available
This study examined if the protective effect of Ellagic acid (EA) against streptozotocin (STZ)-induced diabetic nephropathy (DN) in rats involves activation of Nrf2. Diabetes mellitus was induced by a single i.p dose of STZ (65 mg/kg). The Rats were divided into 5 groups (n = 12/each) and treated for 8 weeks as control, control + EA (100 mg/kg), ST...
Article
Full-text available
Diabetes mellitus induces testicular damage, increases sperm abnormalities, and impairs reproductive dysfunction due to induction of endocrine disturbance and testicular oxidative stress. This study evaluated the reproductive protective effect of ellagic acid (EA) against testicular damage and abnormalities in sperm parameters in Streptozotocin (ST...
Article
Full-text available
Background: Iron deficiency is known to be the most common nutritional disorder. About 30% of the world's population is iron deficient (ID). Women are more likely to be exposed to anemia than men, which is an epidemic public health problem. Objective: A cross-sectional study was carried out to investigate the prevalence of anemia and associated...
Article
This study investigated if cadmium chloride (CdCl2)‐induced hepatic steatosis and fibrosis and the protective effect of quercetin (QUR) are mediated modulating the activity of miR‐21, a known hepatic lipogenic and fibrotic miRNA. Male rats (n = 8/group) were divided as control, control + QUR (50 mg/kg; orally), CdCl2 (10 moml/L; drinking water), Cd...
Article
Full-text available
Ripe date fruits contain phenolic compounds which possess a high antioxidant activity. The current review was carried out to evaluate total phenolic content in ripe date fruits. Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) was followed during the review process. Relevant studies published from inception up to March 20...
Article
Full-text available
This study examined if the Fisetin against streptozotocin-induced diabetic cardiomyopathy (DC) in rats involves regulating cardiac metabolism and suppressing protein kinase R (PKR). Male rats were divided (12/groups) as control (non-diabetic), control + Fisetin, T1DM, and T1DM + Fisetin. Fisetin was administered orally at a final dose of 2.5 mg/kg...
Article
Full-text available
This study investigated the protective effect of ellagic acid (EA) against diabetic cardiomyopathy (DC) in streptozotocin (STZ)-treated rats and examined if the mechanism of protection involves modulating silent information regulator 1 (SIRT1). Adult male rats were divided into 5 groups (n = 12/each) as control, control + EA, diabetes mellitus (DM)...
Article
Full-text available
This study investigated the hypolipidemic and antioxidant effects of the juice and water seed extracts of two pomegranate species from Saudi Arabia and Egypt, and compared them with each other as well as with ellagic acid (EA) in high-cholesterol diet (HCD) fed rats. Compared with the case in rats fed HCD alone, EA and juice or water seed extracts...
Article
Full-text available
This study examined the impact of different cooking methods on fatty acid (FAs) composition of shrimp meat and the ability of these foods to protect against high cholesterol (HC) diet-induced non-alcoholic fatty liver disease (NAFLD) in rats. Shrimp were cooked for 10 min boiled, grilled, or fried in sunflower oil. Rats (n = 6/group) were fed a nor...
Article
This study investigated if the nephroprotective effect of Curcumin in streptozotocin-induced type 1 diabetes mellitus (DM) in rats involves downregulation/inhibition of p66Shc and examined the underlying mechanisms. Rats were divided into 4 groups (n = 12/group) as control, control + Curcumin (100 mg/kg), T1DM, and T1DM + Curcumin. Curcumin was adm...
Article
Full-text available
Introduction Anthropometry and bone mineral density are linked to hormonal imbalance, which plays a possible role in breast carcinogenesis. The current study was designed to explore the relationship between selected anthropometric and bone mineral density parameters and the risk of breast cancer in premenopausal and postmenopausal Saudi women. Mat...
Article
Full-text available
Date palm spathes are by-products of date cultivation, which normally go to waste. To improve sustainability, this study reports the development of a date palm pollen beverage prepared from date palm spathes and examines the impact of ginger and pollen grains on its nutritional and sensory properties. Date spathe pollen beverage fortified with 1% g...
Article
Full-text available
The aim of this study was to fortify date palm spathes beverage with pollen grains. The nutritional quality and sensory attributes of the developed products were evaluated. The results showed that pollen grains significantly (P < 0.05) influenced the nutritional and sensory qualities of date palm spathe beverages. With minor exceptions, fortificati...
Article
Full-text available
At present, the world is facing a pandemic named as COVID-19, caused by SARS-CoV-2. Traditional Chinese medicine has recommended the use of liquorice (Glycyrrhiza species) in the treatment of infections caused by SARS-CoV-2. Therefore, the present investigation was carried out to identify the active molecule from the liquorice against different pro...
Article
Full-text available
Twenty-nine Yemeni honey samples were analyzed to determine total phenolic and flavonoid contents using Folin-Ciocalteu and spectrophotometric technique. These tested honey samples were collected from different regions corresponding to various floral species: jujube, cactus and multifloral plants. Folin-Ciocalteu method was adopted for the analysis...
Article
Full-text available
Type 2 diabetes is an epidemic public health issue worldwide. It is common among adults and is more severe among overweight and obese subjects. This study was conducted to evaluate the effects of a low‐energy diet with and without oat bran and olive oil supplements on body mass index, blood pressure, and serum lipids in women with diabetes. It was...
Article
Purpose The purpose of this study is to investigate the effect of roselle flower extract and date palm pollen on the nutritional and sensory qualities of date palm spathe beverage (DPSB). Design/methodology/approach The nutritional composition and sensorial quality of the date palm spathe-based beverage were evaluated. The product was fortified wi...
Article
The cyclin-dependent kinase-2 (CDK2) belongs to the protein kinase family and its overexpression leads to an unusual regulation of cell-cycle which directly linked with hyperproliferation in many cancer cell types. CDK2 activation spontaneously promotes the cell cycle progression and also involved in a large number of cellular processes including c...
Article
An ultra‐performance liquid chromatography‐tandem mass spectrometric method has been developed for the highly sensitive and selective determination of regulated aflatoxins. The extraction of aflatoxins from baby food matrices were performed using liquid–liquid extraction procedure followed by immunoaffinity column cleanup. The higher sensitivity fo...
Article
Full-text available
Diabetes mellitus (DM) is a metabolic syndrome distinguished with glucose increasing in blood, insulin resistance, and hyperlipidemia. It results in decease of millions of people yearly. Duvalia corderoyi is a traditional diabetes and hypertension medicine from the Arabian region. D. corderoyi extract was administered to diabetes rats for estimate...
Article
Full-text available
An UPLC- mass spectrometry method has been proposed for the screening of carbaryl residues in fresh vegetables. Carbaryl treated samples of lettuce, cucumber and spinach were procured and analyzed for a time period of fifteen days to find out the amount of carbaryl residue. A simple and effective liquid–liquid sample extraction technique has been i...
Article
Full-text available
The aim of the study was to evaluate the effect of Duvalia corderoyi (D. corderoyi) extracts in oxidative stress status and histopathology of liver and kidney tissues in streptozotocin (STZ)-induced diabetic rats. Fifty male Wistar albino rats were injected intraperitoneally (IP) with STZ. Rats with fasting blood glucose levels of 250 mg/dl and abo...
Article
Full-text available
Vitamin D deficiency is an epidemic public health problem worldwide. It is common in the Middle East and is more severe in women. This cross-sectional study was conducted to assess vitamin D deficiency and associated risk factors in women living in Riyadh, Saudi Arabia. Serum 25-hydroxyvitamin D (25(OH)D) was measured in 166 women aged 30–65 years....
Article
Full-text available
A liquid–liquid extraction based high performance liquid chromatography-fluorescence method has been proposed for the quantitation of naturally producing aflatoxins in nuts and nut based products. Aflatoxins extraction from nuts and nut products was involved methanol – water extraction, immunoaffinity column cleanup followed by post column derivati...
Article
Food exchange lists are a practical meal-planning tool. This project was conducted to develop a food exchange list for traditional Saudi foods. The most commonly consumed 25 traditional Saudi foods were selected. The homemade foods (n = 15) were prepared and the out-of-home foods (n = 10) were purchased. Food samples were analyzed for their macronu...
Article
Full-text available
Objectives: To assess the role of serum vitamin D and other nutritional factors in women with breast cancer in Saudi. Methods: A total of 500 women (250 patients with breast cancer and 250 controls) aged 30-60 years were recruited from King Saud Medical City and King Fahad Medical City, Riyadh, Saudi Arabia, between May 2015 and June 2016. In th...
Article
Full-text available
During the last few decades, Saudi Arabia experienced rapid nutritional transition associated with an alarming elevation in the prevalence of obesity and related chronic diseases. Traditional foods contribute to the usual diet of the population in Saudi Arabia and the nutritional evaluation of traditional foods is necessary to accurately estimate d...
Article
Full-text available
Background and Objective: Blood glucose levels can be affected by the various types of chlorophyll. Experiments have proven that chlorophyll has antioxidant activities that are present in various foods. This study aimed to identify the effects of chlorophyll type on blood glucose and body functioning. Methodology: For the study, five different high...
Article
Full-text available
This study was conducted for detecting the relationship between caffeine consumption and the occurrence of prevalent psychological disorders. The study sample consisted of 160 young women whose mean age was 22.96 ± 3.66 years. To collect descriptive data and body measurements and estimate the amount of caffeine consumed, we used a 7-day food regist...
Article
Full-text available
Oggt products (raw, defatted and isolated protein) were used for partial substitution of wheat flour (75% Extraction) for the preparation of pan and pita bread. Each oggt product was added to wheat flour at 3%, 5% and 7%. We studied the influence of this substitution on chemical and physical properties and nutritive value of the bread. We found tha...
Article
Full-text available
Vitamin D deficiency has emerged as a public health problem worldwide due to its important role in health and disease. The present work is intended to examine prevalence of vitamin D deficiency among pregnant Saudi women and related risk factors. A cross-sectional study was carried out at King Fahad Medical City in Riyadh, Saudi Arabia. Serum 25-hy...
Article
Full-text available
Background: Saudi Arabia has passed through lifestyle changes toward unhealthy dietary patterns such as high fast food consumption. Adolescents and young adults, particularly girls, are the main groups exposed to and affected by these adverse eating behaviors. Objective: The aim of this study was to examine the trends of fast food consumption among...
Article
Full-text available
Background: The utilization of herbal formulas is continuously increasing on the global level. However, assessment of contamination and impurities is the leading challenge in the use of herbal medicines. Objective: Assessment of therapeutic application in relation to herbal formulas usage for reducing weight is the objective for this investigati...
Article
Full-text available
This study was conducted to examine the nutritional content, contamination levels, and biological effects of 3 local prepared formulas. Formula (1) contained mixed nuts; formula (2) contained moghat, honey and royal jelly, while formula (3) contained honey, fenugreek and royal jelly. Groups of albino rats (90 rats) were randomly allocated to diets...
Article
Full-text available
Herbal products are often marketed for weight reduction in the Kingdom Saudi Arabia, this study aimed to evaluate weight loss claims and safety of three popular herbal products marketed in Riyadh, Albino rats aged 6–7 weeks were fed a diet comprising 15% mixed herbal products and compared with controls, any changes in weight and food intake were re...
Article
Full-text available
The genetic diversity and relationship amongst the bacterial populations were determined in fresh salad samples (Tabbouleh, Fattoush, Hummus, Mutabbel and Caesar) collected from various restaurants located in five different areas (west, north, south, east and center) in Riyadh (the capital city of Saudi Arabia). Isolated colonies found were identif...
Article
Full-text available
The aim of present investigation was to study the effects of Mesembryanthemum forsskalei Hochst (Samh) seeds in streptozotocin-induced diabetic rats. Thirty rats were administrated with streptozotocin to induce diabetes and 6 rats were used as untreated diabetic control. Diabetic rats were fed with 5 and 15% Samh seed alone and in combination with...
Article
Full-text available
The pathogenesis of a number of diseases like cardiovascular diseases, diabetes and cancer has been associated with changes in the balance of certain trace elements. In the present study we aimed to investigate the levels of trace elements like calcium, copper, iron and zinc in colon cancer patients in comparison with healthy controls. Serum sample...
Article
Full-text available
Genetic variants of endothelial nitric oxide synthase (eNOS) could influence individual susceptibility to coronary artery disease (CAD) with or without associated demographic factors. The aim of this study was to assess whether Glu298/Asp polymorphism of the eNOS gene is associated with the occurrence and severity of angiographycially defined coron...
Article
Full-text available
The genetic diversity and relationship amongst the bacterial populations were determined in fresh salad samples (Tabbouleh, Fattoush, Hummus, Mutabbel and Caesar) collected from various restaurants located in five different areas (west, north, south, east and center) in Riyadh (the capital city of Saudi Arabia). Isolated colonies found were identif...