Noorehan Yaacob

• Bachelor of Science (Mathematics); Master in Science (Engineering Mathematics); PhD in Mathematics
• University of Technology Malaysia

The finger-like protrusions formed by an invasive cancer cell known as invadopodia is actively observed recently because of this formation on the cancer invasion. The signal on the interface which is stimulated upon contact between epidermal growth factor receptor and ligand, is investigated to be the start of invadopodia formation. In this researc...

We studied a delay differential equations model for the population dynamics of diabetes during pregnancy. We considered four variables, namely women who are non-diabetic, women who are diabetic, women with gestational diabetes, and women with gestational diabetes and diabetes-related complications. We investigated the stability analysis of the equi...

Traveling is an exciting activity where visitors can see beautiful places and learn about the culture of other countries. Before traveling to certain places, visitors are required to take vaccines—for example, a quadrivalent meningococcal vaccine for performing Umrah or Hajj in Mecca, Saudi Arabia. However, for new diseases that suddenly appear (re...

Invadopodia are finger-like protrusions that are commonly spotted at the membrane of the invasive cancer cell. These structures are a major cause of death among cancer patients through metastasis process. Signal transduction stimulated upon contact between ligand and membrane receptors is identified as one of key factors in invadopodia formation. I...

Predator-prey model is the study to show the interaction between prey and preda- tor. A stage-structured model is introduced where the mature and immature of the species is considered. Also, the effect of harvesting is taken into account for sustainable development. The model in this paper is explained by using the ordinary differential equations t...

Invadopodia are protrusions that are commonly spotted at the plasma membrane of the invasive cancer cells. In forming invadopodia, several molecular interactions are involved such as the ligand, extracellular matrix (ECM), matrix metalloproteinases (MMPs), actin, and signal which are interrelated. In this paper, the mathematical model of ligand and...

Cancer cell invasion in the metastasis process contributes to the high death cases among cancer patients. The spread of a tumor from one location to the other part of the body is as a result of the existence of finger-like protrusions or invadopodia on the plasma membrane. On the biological view, the formation of invadopodia involves several proces...

The secondary tumor is stated to be more dangerous among cancer patients and this tumor is created through metastasis. Metastasis is the process of spreading a tumor from the primary location to the second part of the human body. This is an unpleasant problem among cancer patients because metastasis can contribute to high mortality cases among them...

Invadopodia are finger-like protrusions located at subcellular membrane which can lead to cancer cell invasion. The formation of invadopodia involves several steps such as actin polymerizations, degradation of extracellular matrix which produce ligand and signal stimulation that is occurred from the binding of ligand with epidermal growth factor re...