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4
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Introduction
Skills and Expertise
Current institution
Education
January 2019 - December 2020
August 2016 - December 2020
Publications
Publications (4)
This review outlines the known cellular pathways and mechanisms involved in Drosophila age-dependent immunity to pathogenic microorganisms such as bacteria and fungi. We discuss the implication of host signaling pathways such as the Toll, Immune Deficiency (IMD), Janus kinase signal transducer and activator of transcription (JAK/STAT), and Insulin/...
Advanced age in humans is associated with greater susceptibility to and higher mortality rates from infections, including infections with some RNA viruses. The underlying innate immune mechanisms, which represent the first line of defense against pathogens, remain incompletely understood. Drosophila melanogaster is able to mount potent and evolutio...
Advanced age in humans is associated with greater susceptibility to and higher mortality rates from infections, including infections with some RNA viruses. The underlying innate immune mechanisms, which represent the first line of defense against pathogens, remain incompletely understood. Drosophila melanogaster is able to mount potent and evolutio...
We investigated how aging impacts Drosophila’s ability to respond to FHV infection. We demonstrate that wild type 30-days-old Drosophila succumb more rapidly to infection in comparison with younger (5-days-old) adults and that the increased mortality is not accompanied by an increase in virus load. These results suggest that mechanisms different fr...
