Nilson N. Mendes Neto

Harvard Medical School | HMS

Background Monkeypox virus person-to-person transmission mostly occurs by personal contact with an infected individual or surface. We used the classical susceptible-infectious-removed (SIR) epidemic model (Figure 1) to forecast the virus spread in a simulated population. Diagram of the SIR epidemic model Methods SIR model equations (ds/dt = −βsi;...

How many people might be infected by monkeypox virus? This study has a possible answer. By using a realistic simulation and computer intelligence, we forecasted the spread of monkeypox virus.

Background: An increase in the prevalence of microcephaly (MCP) was observed in Rio Grande do Norte State (RN) beginning in September 2015. This Brazilian Northeast state was highly impacted by a Zika vírus (ZIKV) outbreak over the subsequent two years. The highest rate of MCP was measured in November 2015, at 20.1 cases per 1,000 live births, comp...

Background Congenital Zika Syndrome (CZS) has a broad spectrum of clinical presentations that are still being described. This cohort study aimed to describe the orthopedic complications in children with microcephaly (MCP) related to Zika virus (ZIKV). Methods We evaluated 36 children with CZS up to 17 months of age followed at a pediatric rehabili...

Background Infant mortality in Brazil has increased for the first time in 26 years. This study aimed to define the Zika Syndrome (ZS) perinatal case fatality rate (PCF) since the 2015 Zika outbreak in a Brazilian northeast state highly impacted by the virus. Methods Cross-sectional study conducted using data obtained through the State Health Depar...

Background: Infant mortality in Brazil has increased for the first time in 26 years. This study aimed to define the Zika Syndrome (ZS) perinatal case fatality rate (PCF) since the 2015 Zika outbreak in a Brazilian northeast state highly impacted by the virus.

Hypothalamic deep brain stimulation (DBS) has been used for more than a decade to treat cluster headache (CH) but its mechanisms remain poorly understood. The authors have successfully treated a patient with CH using hypothalamic DBS and found that the contact used for chronic stimulation was located in a white matter region posterior to the mammil...

Corresponding author Nilson N Mendes Neto Department of Medicine, Onofre Lopes University Hospital, Natal, Brazil nmendes@ucdavis.edu Received Date: 05 September 2018 Accepted Date: 23 January 2019 Published Date: 25 January 2019 DOI: 10.31021/jnn.20192126 Article Type: Case Report Manuscript ID: JNN-2-126 Publisher: Boffin Access Limited. Vol...

Background Many studies have demonstrated a causal link between Zika virus (ZIKV) infection, microcephaly (MCP) and other congenital abnormalities (CA). This study aimed to determine the perinatal case fatality rate in cases of Congenital Zika Syndrome (CZS) in the Rio Grande do Norte State (RN), a Brazilian Northeast State highly impacted by the Z...

Background Preexisting DENV antibodies may have a cross-reactivity against ZIKV. A recent primate study suggested that prior DENV infection does not adversely impact subsequent ZIKV disease and might be protective. This study aimed to evaluate the relation between a Dengue Fever (DF) outbreak in 2016 and the prevalence of ZIKV infection in Rio Gran...

Background Although Zika virus (ZIKV) infection causes a broad-spectrum of congenital neurological disorders, radiographic correlates of clinical outcome are lacking. During 2015–2016 ZIKV outbreak we faced a high incidence of microcephaly (MCP) in Rio Grande do Norte State (RN), located in northeast of Brazil. Among all regions, the northeast was...

Background Studies have demonstrated radiological findings in microcephaly (MCP) related to Zika virus (ZIKV). The 2015–2016 ZIKV epidemic leaded to an increase in the prevalence of MCP in the northeast region of Brazil. Rio Grande do Norte State (RN), a Brazilian northeast state, was highly impacted by this outbreak. This study aimed to evaluate C...

INTRODUCTION Studies using functional MRI showed the ipsilateral posterior hypothalamus activation during the cluster headache episodes. The deep brain stimulation of the posterior hypothalamic (DBS-PH) area was introduced in 2000 in order to treat drug-resistant chronic cluster headache (CCH). METHODS Systematic Research using databases including...

Objective: To assess the efficacy of Percutaneous Balloon Compression (PBC) and to evaluate the factors influencing the outcome. Background: PBC is a therapeutic option available to treat Trigeminal Neuralgia (TN). TN is one of the most painful conditions known. Design/Methods We performed a retrospective study on 222 patient’s records which have...

Objective: To provide the current number of CCH patients treated with DBS-PH and the efficacy of treatment. Background: Studies using functional MRI showed the ipsilateral posterior hypothalamus activation during the cluster headache (CH) episodes. The deep brain stimulation of the posterior hypothalamic (DBS-PH) area was introduced in 2000 in ord...

Background Pertussis, also called whooping cough, is an acute infectious disease of high transmissibility transmitted through aerosol particles released during the catarrhal phase and paroxysmal cough. Since the 1990s its incidence has increased and atypical clinical forms have been identified, mainly in newborns and adults. We hypothesized that th...

Background Many studies have demonstrated a causal link between Zika virus (ZIKV) infection, microcephaly (MCP), and other congenital abnormalities (CA). This study aimed to determine perinatal case fatality rate in cases of Congenital Zika Syndrome (CZS) in the Rio Grande do Norte State (RN), a Brazilian Northeast State highly impacted by the Zika...

Background An increase in the prevalence of microcephaly (MCP) was seen in Rio Grande do Norte State (RN) since September 2015. This Brazilian northeast state was highly impacted by a Zika (ZIKV) outbreak in the last 2 years. The highest rate of MCP was in November 2015 with 20.1 cases per 1,000 live births, compared with 1.8 cases/year in the prev...

INTRODUCTION Percutaneous balloon compression of the Gasserian ganglionic has been used to treat Trigeminal Neuralgia (TN) since 1983. METHODS We performed a retrospective study on 222 patient's records which have received 242 procedures of Percutaneous Balloon Compression (PBC) as treatment for TN. A 6 months follow-up period after surgery was ne...

Objective: To provide data on the current number of CCH patients treated with stimulation of the posterior hypothalamus, the efficacy of treatment and side effects.