
Nilesh Nirmal- PhD in Food Science and Technology
- Global Talent Leader at Mahidol University
Nilesh Nirmal
- PhD in Food Science and Technology
- Global Talent Leader at Mahidol University
Open for research collaboration in food science & technology, nanotechnology, co-supervision, and related opportunities
About
172
Publications
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Introduction
Nilesh Nirmal is a Global Talent Leader at the Institute of Nutrition, Mahidol University, Thailand. His research interest focuses on waste (fruit, vegetables, and seafood) utilization for value-added products. He is expertise in the evaluation of plant-based food additives as a replacement for synthetic chemicals. He also has an interest in the application of bioactive compounds using nanotechnology. For research collaboration and other scientific activities, please feel free to drop a message
Current institution
Additional affiliations
January 2014 - December 2014
Publications
Publications (172)
Responsible consumption and production are one of the sustainable development goals. Antioxidant plays a crucial role in the prevention of oxidative deterioration of poultry and farm animal feed. This study examined the physical (moisture content, ash content, flow ability) and antioxidant properties of commercially available natural (Ozox A and Oz...
Maintenance of metabolic health is challenging due to lifestyle and the fact that metabolic syndrome and its associated diseases are common. Investigation into novel therapeutics for the prevention and/or treatment of metabolic diseases has shown that phytoextracts carry potential. Preclinical research has demonstrated that phytochemicals such as b...
Food packaging is one of the most important strategies to prevent food damage or spoilage during storage and the supply chain. Among various food types, seafood, a high-value product, is particularly vulnerable to post-harvest quality loss and microbial contamination during storage. Although current plastic-based packaging materials are durable, th...
Recently, bioactive peptides, from natural resources, have attracted remarkable attention as nutraceutical treasures and the health benefits of their consumption have extensively been studied. Therapies based on bioactive peptides have been recognized as an innovative and promising alternative method for dangerous diseases such as cancer. Indeed, t...
Purpose of Review
The diverse polyphenolic components present in these berries are responsible for their functional properties in human health. Hence, there is an increasing demand for research in berry bioactive components to understand the mechanism of action in alleviating and preventing diseases. Therefore, in this last part-III of the review s...
Purpose of Review
This review delves comprehensively into the nutritional profiles and diverse biological activities of different berries. So far 19 different types of berries have been identified for human consumption and studied for their nutritional and biological activities. Among them, acai berry, blueberry, blackberry, black currant, boysenbe...
Purpose of Review
Berries are a great source of fiber, polyunsaturated fatty acids, and beneficial secondary metabolites (polyphenols). Various phytochemicals present in berries (glycosidic-linked flavonoids, anthocyanins, etc.) provide potential health benefits to consumers. Berries are known as high antioxidant food which provides certain cellula...
Grape wine processing is one of the topmost industries in the agricultural sectors worldwide where 75 vol% of grape production is utilized for winemaking. The winemaking process leaves behind 20-30 wt% by-products or wastes. This winery waste contains a large number of sugars, fibers, phenolic compounds, pigments, and other organic compounds which...
The projected global population increase to 8.60 billion by 2050 and 11.20 billion by 2100 underscores the urgent need for sustainable solutions to secure essential food resources, particularly protein, for human health. Traditional animal‐based proteins, while nutritionally rich, are environmentally costly due to greenhouse gas emissions, extensiv...
For several decades, liposomes have been utilized to encapsulate pharmaceuticals and bioactive compounds in cosmeceuticals. However, in the past decade, there has been a notable increase in the application of these phospholipid vesicles in nutraceuticals and food applications. The delivery of vitamins, especially those that are poorly water-soluble...
Employee churn or attrition presents significant challenges, especially in emerging markets, where it can disrupt business operations and inflate recruitment costs. This research leverages machine learning techniques to predict employee churn, focusing on developing sustainable and inclusive retention strategies that enhance business competitivenes...
Nanotechnology has come up as an advanced domain in the food packaging field that has proved to be an effective solution for increasing shelf life and ensuring food products’ safety. Integration of metal-based nanoparticles with different packaging materials enhances the physical, chemical, mechanical, and thermal characteristics resulting in the r...
The standard ice cream consists of high calories and fat which could cause metabolic syndrome upon regular consumption. Therefore, this study developed a fat‐free ice cream using fat replacer including inulin (carbohydrate‐based) and whey protein isolate (WPI, protein‐based) at various concentrations (6%, 8%, and 10%) or their combination (1:1). Ad...
Citrus hystrix essential oil (CHEO) have shown various pharmacological properties including antibacterial activity. This EO also possessed antibacterial effect against foodborne pathogens. There is less information available about the synergy interaction between CHEO and tetracycline, as well as their mechanism of action. Therefore, this study was...
Seafood is abundant in high-quality protein, healthy fats (n-3 and n-6 PUFAs), minerals (calcium, magnesium, copper, selenium, and so on), and vitamin D. Functional compounds in seafood can protect against lifestyle-related diseases. Having had all the merits mentioned, it is also a highly putrefiable food item. To maintain quality and prolong seaf...
Rohu fish (Labeo rohita) fillets were coated with 2.5 to 25% soy protein isolate (SPI) to evaluate their ability to reduce fat-uptake. The coating pickup of coated fish fillets increased with increasing coating concentration. Fillets coated with 15% SPI showed the highest coating pick-up value of 18.29% and reduced fat uptake by 57.78%. As revealed...
Antibiotics in poultry feed to boost growth performance are becoming increasingly contentious due to concerns over antimicrobial resistance development. Essential oils (EOs), as natural, plant-derived compounds, have demonstrated antimicrobial and antioxidant properties. EOs may potentially improve poultry health and growth performance when include...
Mud crab (Scylla olivacea) is a valuable crustacean that has been consumed as nutritious foods for human body maintenance, delicacy tasting and for medicinal purposes. This study aimed to develop a novel mud crab extract processed through lactic acid fermentation. The objective is to compare the nutritional value, antioxidant properties and lipid p...
Global food security has recently been under serious threat from the rapid rise in the world's population, the problems brought on by climate change, and the appearance of new pandemics. As a result, the need for novel and innovative solutions to solve the existing problems and improve food sustainability has become crucial. 3D printing is expected...
Seafoods are susceptible to microbial contamination due to their high moisture, nutrient contents and neutral pH. Among various microorganisms, biofilm-forming bacteria pose a severe threat to the seafood supply chain as well as consumer health. Bacterial biofilm formation in seafood is primarily caused by Aeromonas hydrophila, Vibrio cholerae, V....
The rise in the global population has increased the demand for dietary food protein. Strategies to maximize agricultural and livestock outputs could strain land and freshwater supply and contribute to substantial negative environmental impacts. Consequently, there has been an emphasis on identifying alternative sources of edible proteins that are m...
Mango (Mangifera indica) has been one of the most cultivated fruits in Thailand and other South and Southeast Asian countries. ‘Bao’ mango is a distinct petite mango variety that is available all year round. This study aimed to investigate the antioxidant and anti‐breast cancer activities of Bao‐mango peel extract (MPE). The total phenolic content...
Plant proteins have been considered a potential source of bio-functional peptides, which can be beneficial for human health. The potent antioxidant properties of plant-based peptides protect against oxidative damage and associated diseases. Despite a significant number of studies on the preparation and biological functions of plant-based peptides,...
Bacterial contamination and infection widely affect the food, pharmaceutical and biomedical industries. Additionally, these bacteria developed resistance to synthetic antibiotics causing public health danger, globally. Natural plant extracts (NPE) are suitable alternatives to synthetic antibiotics to tackle antimicrobial resistance problems. Furthe...
Shell waste from shellfish processing contains valuable natural polysaccharides, including sulfated poly-saccharides, acidic polysaccharides, glycosaminoglycans, chitin and their derivatives. These shellfish waste-derived polysaccharides have numerous functional and biological properties that can be applied in various industries , including the cos...
The present study investigated the antioxidant and antimicrobial activities of Bao mango and daikon radish peel (Thai variety) ethanolic extracts. The percentage extraction yield of radish peel was higher compared to the mango peel (p < 0.05). However, Mango peel extract (MPE) contained higher total phenolic content (TPC) than radish peel extract (...
Betalains are natural coloring pigments with betalamic acid as the core structure of all subclasses. Besides their coloring properties, betalains exhibit various biological activities, including antioxidant and anti-inflammatory properties, which are highly imperative. Further in-vivo studies reported that betalains protect various body organs, lea...
Citation: Kettawan, A.; Ruangklai, S.; Rungruang, T.; Thongam, J.; Kettawan, A.K.; Nirmal, N.; Srisuma, S. Rice Bran Oil Improves Emphysema in Cigarette Smoke Extract-Induced Mice through Anti-Inflammatory and Antioxidative Effects. Nutrients 2024, 16, 433. Abstract: Lung inflammation and alveolar enlargement are the major pathological conditions o...
The greatest difficulty facing the cosmos now is the ability to survive in excellent health. The idea that nature preserves plant seeds when they are dormant and have been sitting in the soil for a long time is the foundation for the current notion. Bacteria, fungus, and virus attack are deterred from attacking seeds with the assistance of antimicr...
Globally, fruits and vegetables generate almost half of total food waste, which has become a major environmental concern. Though the ample amounts of fruit by-products are considered as industrial waste and usually disposed of or used as animal feed and biofuel, they can be a great source of nutraceuticals and bioactive compounds. Studies have sugg...
The successively growing consumer interest in natural bioactive compounds associated with human health promotion and disease prevention has received huge attention in the food market toward effective extraction techniques. Bioactive compounds can be extracted from natural sources and commercially utilized in the development of nutraceuticals and fu...
Alternative methods are currently being investigated to reduce the overuse of organic solvents, which have serious environmental and health consequences. Certain promising green technology-based alternative extractions are employed in a wide range of bioactive and nutraceutical extractions, including ultrasonication, microwave-assisted extraction,...
The marine resource hosts wide biodiversity, regarded as a rich source of diverse bioactive compounds, which are widely investigated for their bioactive composition and nutraceutical applications having several health benefits. Several in vitro and in vivo studies have reported the impacts of marine bioactive compounds in controlling several lifest...
In recent years, application of the computational approach, a predictive tool, in food and nutritional sciences has outweighed classical analytical methods. The sophisticated informatics approaches such as chemo-informatics and bioinformatics methods are integrated with the food industry for the extraction and identification of bioactive compounds....
Functional foods derived from milk are essential for human health, including fermented milk, dairy beverages, cheeses, and dairy sweets. The nutritional composition of different milk sources varies, impacting the qualities of resultant functional foods. Goat milk has health-promoting compounds, including calcium, medium-chain fatty acids, and α-cas...
Beetroot juice is a popular natural food supplement commonly consumed for its health and ergogenic benefits. It contains an abundance of phytochemical compounds, which have been shown to enhance sports endurance and recovery. Among them, nitrate is well-studied and known for improving performance during exercise. On the other hand, betalains, the b...
INTRODUCTION
This study focused on the formulation processing and antimicrobial activities of Origanum and Thyme essential oils (OEO) (TEO) and their nanoemulsions (OEON) (TEON) on gram-positive and gram-negative bacteria and yeast. Optimal nanoemulsion formulation and stability were achieved through balancing between requisite hydrophilic-lipophil...
Purpose of Review:
Dietary consumption of prebiotics, probiotics, and synbiotics has been suggested to improve human
health conditions. Functional food products containing live probiotics are flourishing, and their demand seems to be increasing since consumers are more aware of the health benefits of such products. However, specific food packaging...
Corn processing industries generate an extensive fibrous byproduct consisting of corn fiber gum (CFG) and residual starch (S). The present study hypothesized that CFG and S could be isolated as a single crosslinked conjugate. The isolated CFG-S conjugate was acidic, with a pKa value of 11.49, and a swelling index of 99.60%. Henderson-Hasselbalch eq...
Food industries are developing new processing technologies, resulting in the emergence of new product categories, including ready-to-eat meals, functional foods and beverages, and plant-based foods, etc. Rapid globalization, changes in lifestyle, consumer awareness, and perception toward food drive further technical advancements. However, consumer...
Seafood is a high-value market product well known for its nutrition and easily digestible protein. However, they are highly vulnerable to postharvest storage such as microbial deterioration and oxidation process (protein and lipid oxidation). Hence, various strategies have been employed to preserve the quality of seafood products, including chemica...
This study explored the impact of date palm seeds ethanolic extract (DSEE) on the microbiological, physicochemical, and sensory qualities of chicken breast meat kept refrigerated at 4 °C. DSEE was applied at 0.156% (DSEE1), 0.312% (DSEE2), and 0.624% (DSEE4). Microbiological parameters, chemical stability, and sensory features of DSEE were monitore...
The development of biodegradable packaging is a challenge, as conventional plastics have many advantages in terms of high flexibility, transparency, low cost, strong mechanical characteristics, and high resistance to heat compared with most biodegradable plastics. The quality of biodegradable materials and the research needed for their improvement...
Muscle foods are the main source of high protein and mineral content. However,
these foods are highly perishable due to their high moisture content as well as
nutritional composition. Generally, microbial changes and oxidative damage
occurs during animal slaughter and storage. To avoid this quality deterioration,
various chemical additives are wide...
Cancer is a hereditary multifactorial disease, and due to its rising incidence in both young people and adults along with its substantial burden, oncological emphasis has been placed more on preventive efforts. It has been suggested that several food and lifestyle choices contribute to the onset of cancer, presumably via complex metabolic and infla...
Purpose of Review
Metabolic syndrome is continuously increasing among the world’s populations. Metabolic syndrome is a medical condition in which individuals suffer from high blood pressure, high blood glucose levels, and obesity. The in vitro and in vivo bioactivities of dairy milk protein–derived peptides (MPDP) have proven their potential as an...
Fish and other seafood products represent a valuable source of many nutrients and micronutrients for the human diet and contribute significantly to global food security. However, considerable amounts of seafood waste and by-products are generated along the seafood value and supply chain, from the sea to the consumer table, causing severe environmen...
Texture is an important sensory attribute for overall quality and consumer acceptance of prawns. However, texture is affected during cold storage due to the proteolytic activity of endogenous proteases, resulting in poor quality and a short shelf life. The objective of this study is to determine the inhibitory effects of Annona muricata leaves extr...
The World Health Organization's emphasis on the health benefits of functional foods and beverages that has contributed to the rise in its popularity globally. Besides these consumers have become more aware of the importance of their food composition and nutrition. Among the fastest-growing market segments within the functional food industries, the...
Citation: Sinchaipanit, P.; Sangsuriyawong, A.; Visetchart, P.; Nirmal, N.P. Formulation of Ready-to-Eat Soup for the Elderly: Nutritional Composition and Storage Stability Study. Foods 2023, 12, 1680. Abstract: Lack of appetite is a common problem in elderly people which could lead to the risk of malnutrition. Soup-based product formulation and su...
Amphibians have been consumed as an alternative protein source all around the world due to their delicacy. The skin of edible amphibians, particularly frogs and giant salamanders, always goes to waste without further utilization. However, these wastes can be utilized to extract protein and bioactive peptides (BPs). Various BPs have been extracted a...
Simple Summary
This study investigated a comparative analysis on changes in protein and lipid fractions and quality attributes of camel meat, cattle meat (beef) and sheep meat (mutton). The samples were studied over 9 days of refrigerated storage. Camel meat underwent higher lipid oxidation compared with beef and sheep meat. All meat types showed a...
Milk protein hydrolysates derived from 4 camel breeds (Pakistani, Saheli, Hozami, and Omani) were evaluated for in vitro inhibition of antidiabetic enzymatic markers (dipeptidyl peptidase IV and α-amylase) and antihypercholesterolemic enzymatic markers (pancreatic lipase and cholesterol esterase). Milk samples were subjected to in vitro simulated g...
Muscle foods are regarded as nutritionally dense foods while they are prone to spoilage by action of microorganism and oxidation. Recently, the consumer’s preference is mostly toward minimally processed foods as well as preserved with natural preservatives. However, natural extract directly to the food matrix has several drawbacks. Hence developmen...
The fruit production and processing sectors produce tremendous amounts of by-products and waste that cause significant economic losses and an undesirable impact on the environment. The effective utilization of these fruit wastes can help to reduce the carbon footprint and greenhouse gas emissions, thereby achieving sustainable development goals. Th...
The fruit production and processing sectors produce tremendous amounts of by-products and waste that cause significant economic losses and an undesirable impact on the environment. The effective utilization of these fruit wastes can help to reduce the carbon footprint and greenhouse gas emissions, thereby achieving sustainable development goals. Th...
Four tannin samples extracted from chestnut wood (tannin oenologique, TO), grape (tannin VR grape, TVG), oak gall (tannin galalcool, TG), and oak tree (tannin VR supra elegance, TE) were evaluated for antioxidant and antibacterial activity. The highest total phenolic content (TPC) values were observed in the order of TVG > TG > TE > TO (p < 0.05)....
The ocean is a treasure trove of both living and nonliving creatures, harboring incredibly diverse group of organisms. A plethora of marine sourced bioactive compounds are discovered over the past few decades, many of which are found to show antibiofilm activity. These are of immense clinical significance since the formation of microbial biofilm is...