Nikki Buckner

Nikki Buckner
North Bristol NHS Trust · Southmead Hospital

Doctor of Philosophy

About

4
Publications
370
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329
Citations
Additional affiliations
October 2016 - present
University of Bristol
Position
  • PhD Student
Description
  • PhD in Translational Health Sciences, funded by GW4 BioMed MRC DTP

Publications

Publications (4)
Article
Elevated levels of vascular endothelial growth factor (VEGF) A are thought to cause glomerular endothelial cell (GEnC) dysfunction and albuminuria in diabetic nephropathy. We hypothesized that VEGFC could counteract these effects of VEGFA to protect the glomerular filtration barrier and reduce albuminuria. Isolated glomeruli were stimulated ex vivo...
Article
Full-text available
The microtubule-associated protein Tau plays a critical role in the pathogenesis of Alzheimer disease and several related disorders (tauopathies). In the disease Tau aggregates and becomes hyperphosphorylated forming paired helical and straight filaments, which can further condense into higher order neurofibrillary tangles in neurons. The developme...

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