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Nicolas Vuillerme

Nicolas Vuillerme
Institut Universitaire de France & Université Grenoble Alpes, France

PhD

About

449
Publications
87,272
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7,463
Citations
Citations since 2016
174 Research Items
4350 Citations
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20162017201820192020202120220200400600800
20162017201820192020202120220200400600800

Publications

Publications (449)
Article
Full-text available
Background The goal of the study was to investigate patients’ with systemic rheumatic diseases and healthcare professionals’ experiences and preferences regarding self-sampling of capillary blood in rheumatology care. Methods Patients performed a supervised and consecutive unsupervised capillary blood self-collection using an upper arm based devic...
Article
This qualitative descriptive study aims to explore the lived experience of the adjustment process of couples who face vision loss, investigating the impact of such loss on daily life and the adjustments and adaptations that ensue. To undertake such an exploration, the application of an occupational perspective is relevant where the meaning and purp...
Article
Full-text available
Background Previous studies have demonstrated telemedicine (TM) to be an effective tool to complement rheumatology care and address workforce shortage. With the outbreak of the SARS-CoV-2 pandemic, TM experienced a massive upswing. However, in rheumatology care, the use of TM stagnated again shortly thereafter. Consequently, the factors associated...
Article
Background: Physical activity programs at the workplace have shown positive results on physical capacities and pain for several years. Due to the duration of the training session or the need for an instructor, these supervised programs are rather difficult to implement. For this reason, numerous companies, especially companies in manual sectors, a...
Article
Full-text available
This work presents a novel transportation mode detection algorithm that handles the recognition of kick-scooters. In 2015, 10 minutes of data from a kick-scooter were considered in a transportation mode detection study, yielding a 56% F1-score. Since then, kick-scooters were not given much attention. Yet, kick-scooters are now very present in the u...
Article
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Objective A steadily increasing demand and decreasing number of rheumatologists push current rheumatology care to its limits. Long travel times and poor accessibility of rheumatologists present particular challenges for patients. Need-adapted, digitally supported, patient-centered and flexible models of care could contribute to maintaining high-qua...
Article
Full-text available
Patient-reported outcomes (PRO) represent a cornerstone in the management of patients with rheumatoid arthritis (RA). However, PRO are currently recorded mainly on paper and only during on-site appointments. Electronic PRO (ePRO) enable continuous remote monitoring and could improve shared decision-making (SDM) and implementation of a treat-to-targ...
Article
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Introduction Being able to independently determine vaccine induced antibody responses by minimal-invasive methods is of great interest to enable a flexible and effective vaccination strategy. This study aimed to evaluate (1) the accuracy, feasibility, usability and acceptability of capillary blood and saliva self-sampling to determine SARS-CoV-2 an...
Article
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: Backward walking often occurs in everyday life. It is more complex than forward walking and is associated with decreased coordination. However, it is unclear if a reduced backward walking performance is associated with impaired cognition. This could be particularly relevant as gait and cognitive deficits commonly occur in Parkinson’s disease. The...
Article
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Background: The "walk-along interview" (WAI) is a qualitative spatial method that consists of a researcher walking alongside a participant during the time of an interview to identify perceived neighborhood environments. The use of the WAI method increased in various disciplines , including the fields of public health and gerontology, to assess the...
Article
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Objectives To evaluate the feasibility, accuracy, usability and acceptability of two upper arm self-sampling devices for measurement of autoantibodies and C reactive protein (CRP) levels in patients with immune-mediated rheumatic diseases (IMRDs). Methods 70 consecutive patients with IMRD with previously documented autoantibodies were assigned to...
Article
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Symptom checkers are increasingly used to assess new symptoms and navigate the health care system. The aim of this study was to compare the accuracy of an artificial intelligence (AI)-based symptom checker (Ada) and physicians regarding the presence/absence of an inflammatory rheumatic disease (IRD). In this survey study, German-speaking physicians...
Article
Striking an obstacle while walking can be dangerous, reflecting the higher risks of losing one’s balance, tripping and falling. Particular situations during which internal resources are limited, such as in a fatigued state, may impair performance when crossing obstacles, enhancing the risks of falls or accidents. Our goal was thus to review the eff...
Article
Background: Axial spondyloarthritis (axSpA) may lead to functional and physical disturbances. Self- administered questionnaires can measure functional limitations associated to axSpA. If these questionnaires are currently used in clinical practice and research, the French version of these questionnaires has not been validated. The aim of this study...
Article
Background Axial spondyloarthritis (axSpA) is an inflammatory rheumatic disease associated with chronic back pain and restricted mobility and physical function. Increasing physical activity is a viable strategy for improving the health and quality of life of patients with axSpA. Thus, quantifying physical activity and sedentary behavior in this pop...
Article
Full-text available
Introduction Rheport is an online rheumatology referral system allowing automatic appointment triaging of new rheumatology patient referrals according to the respective probability of an inflammatory rheumatic disease (IRD). Previous research reported that Rheport was well accepted among IRD patients. Its accuracy was, however, limited, currently b...
Article
Full-text available
Parkinson’s disease (PD) is a complex neurodegenerative disease with a multitude of disease variations including motor and non-motor symptoms. Quality of life and symptom management may be improved with physical activity. Due to technological advancement, development of small new wearable devices recently emerged and allowed objective measurement o...
Article
Full-text available
Background Rheumatoid arthritis (RA) requires early diagnosis and tight surveillance of disease activity. Remote self-collection of blood for the analysis of inflammation markers and autoantibodies could improve the monitoring of RA and facilitate the identification of individuals at-risk for RA. Objective Randomized, controlled trial to evaluate...
Article
Background Rheumatoid arthritis (RA) requires early diagnosis and tight surveillance of disease activity. Patient self-sampling of blood for the analysis of autoantibodies and inflammation markers could facilitate the identification of patients at-risk for RA and improve tight disease monitoring [1]. Objectives A randomized, controlled trial to ev...
Article
Full-text available
Background: Overweight and obesity are significant global health concerns that involve deficits in gait and balance that affect daily activities. Although much is reported about the effect of overweight and obesity on gait during unobstructed walking, not much is known about how overweight and obesity could impact gait under more challenging condi...
Article
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Introduction An increasing number of digital tools, including dedicated diagnostic decision support systems (DDSS) exist to better assess new symptoms and understand when and where to seek medical care. The aim of this study was to evaluate patient's previous online assessment experiences and to compare the acceptability, usability, usefulness and...
Article
Full-text available
Background Age-related changes in muscle properties affect daily functioning, therefore a reliable assessment of such properties is required. We examined the effects of age on reliability, muscle quality and interrelation among muscle architecture (MA) parameters of the gastrocnemius medialis (GM), tibialis anterior (TA), and vastus lateralis (VL)...
Article
Full-text available
Population aging and urban development pose major challenges for societies today. Joining the literature assessing urban accessibility, the present exploratory research developed a multivariate accessibility model based on four independent variables—related to formal and structural urban space—that influence walkability for older adults (pedestrian...
Article
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Background Walking speed predicts many clinical outcomes in old age. However, a comprehensive assessment of how walking speed affects accelerometer based quantitative and qualitive gait measures in younger and older adults is lacking. Research question What is the relationship between walking speed and quantitative and qualitive gait outcomes in yo...
Article
Full-text available
Innovative strategies are needed to adequately assess and monitor disease activity of patients with rheumatoid arthritis (RA) in times of scarce appointments. The aim of the TELERA study is to evaluate the feasibility and performance of asynchronous telemedicine visits based on patient-generated data and patient's drug history. RA patients use a me...
Article
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Despite all its promises, telemedicine is still not widely implemented in the care of rheumatic and musculoskeletal diseases (RMDs). The aim of this study is to investigate opportunities, barriers, acceptance, and preferences concerning telemedicine among RMD patients and professional stakeholders. From November 2017 to December 2019, a participato...
Article
Full-text available
Background Axial spondyloarthritis (axSpA) is a subgroup of inflammatory rheumatic diseases. Practicing regular exercise is critical to manage pain and stiffness, reduce disease activity, and improve physical functioning, spinal mobility, and cardiorespiratory function. Accordingly, monitoring physical activity and sedentary behavior in patients wi...
Article
Full-text available
Background Axial spondyloarthritis (axSpA) can lead to spinal mobility restrictions associated with restricted lower limb ranges of motion, thoracic kyphosis, spinopelvic ankylosis, or decrease in muscle strength. It is well known that these factors can have consequences on spatiotemporal gait parameters during walking. However, no study has assess...
Article
This study aimed to investigate if the impairing in postural control, induced by ankle fatiguing exercise, remains after 24/48 hours in young adults. Center of Pressure (CoP) was assessed in 16 participants (23±3 years old) before, immediately after an ankle fatigability induction protocol (FI) and after 24 or 48 h of recovery using two 60-s trials...
Article
Full-text available
The number of steps per day influences blood pressure and health. However, the association between steps at work and leisure and blood pressure is unknown. Thus, we aimed to investigate the association between the domain‐specific number of steps and systolic blood pressure. A thigh‐worn accelerometer was used to measure the steps of 694 workers ove...
Article
Full-text available
Studies on the effects of dual tasking in patients with chronic inflammatory rheumatic diseases are limited. The aim of this study was to assess dual tasking while walking in patients with axial spondyloarthritis (axSpA) in comparison to healthy controls. Thirty patients with axSpA and thirty healthy controls underwent a 10-m walk test at a self-se...
Article
Axial spondyloarthritis (axSpA) is a chronic inflammatory disease predominantly affecting the axial skeleton. axSpA includes radiographic (i.e., ankylosing spondylitis (AS)) and non-radiographic forms (nr-axSpA). Although recent studies have reported that patients with AS have impaired gait, axSpA’s consequences on gait remain unknown. The present...
Article
Full-text available
Background An increasing number of diagnostic decision support systems (DDSS) exist to support patients and physicians in establishing the correct diagnosis as early as possible. However, little evidence exists that supports the effectiveness of these DDSS. The objectives were to compare the diagnostic accuracy of medical students, with and without...
Article
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In this current opinion, we discussed the counterintuitive increase in gait speed after experimentally-induced fatigability.
Article
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The World Health Organization has presented their recommendations for energy expenditure to improve public health. Activity trackers do represent a modern solution for measuring physical activity, particularly in terms of steps/day and energy expended in physical activity (active energy expenditure). According to the manufacturer's instructions, th...
Article
Full-text available
Nowadays, gait assessment in the real life environment is gaining more attention. Therefore, it is desirable to know how some factors, such as surfaces (natural, artificial) or dual-tasking, influence real life gait pattern. The aim of this study was to assess gait variability and gait complexity during single and dual-task walking on different sur...
Article
Full-text available
Introduction: Parkinson's disease (PD) is a complex neurodegenerative disease with motor and nonmotor symptoms with a multitude of disease variations and severity. Physical activity can improve the management of disease symptoms and increase patients' quality of life. Technological development of small wearable devices allows objective activity me...
Article
Full-text available
We present spread parameters for first and second waves of the COVID-19 pandemic for USA states, and for consecutive nonoverlapping periods of 20 days for the USA and 51 countries across the globe. We studied spread rates in the USA states and 51 countries, and analyzed associations between spread rates at different periods, and with temperature, e...
Article
Full-text available
Introduction: Mobile applications promise to improve current health care. However, current mobile app quality ratings are mostly physician-based. The aim of this study was (1) to assess the quality of the self-management app Rheuma Auszeit using the validated uMARS (User Version of the Mobile App Rating Scale) app quality assessment tool and (2) to...
Preprint
BACKGROUND Patients suffering from inflammatory bowel diseases (IBD) frequently need long-term medical treatment. Mobile apps promise to complement and improve IBD management, however, so far there is no scientific analysis of their quality. OBJECTIVE To evaluate the quality of German IBD mobile apps targeting inflammatory bowel disease patients a...
Article
Background: Patients suffering from inflammatory bowel disease (IBD) frequently need long-term medical treatment. Mobile apps promise to complement and improve IBD management, but so far there has been no scientific analysis of their quality. Objective: This study evaluated the quality of German mobile apps targeting IBD patients and physicians...
Conference Paper
Kick-scooters detection in sensor-based transportation mode classification methods. Abstract: In this work we present a novel classification model that can detect kick-scooters from inertial and pressure sensors. The detection is performed with kick-scooters being trained with other activities and transportation modes including still, walking, biki...
Article
Full-text available
The present study was designed to assess time-of-day effects on postural balance and symptoms of rheumatoid arthritis (RA) patients. A total of 15 American College of Rheumatology functional class I and II RA patients and 15 healthy controls aged between 45 and 55 (mean age: 50 ± 3) years of age voluntarily participated. We conducted a case-control...
Article
Full-text available
Inertial measurement units (IMUs) are increasingly popular and may be usable in clinical routine to assess gait. However, assessing their intra-session reliability is crucial and has not been tested with foot-worn sensors in healthy participants. The aim of this study was to assess the intra-session reliability of foot-worn IMUs for measuring gait...
Preprint
BACKGROUND Mobile applications promise to improve current health care. A growing number app quality studies exist to help patients and physicians choose appropriate, helpful and useful applications. However, current mobile app quality ratings are mostly physician-based. They exclude patients although as end-users, patients are able to provide the m...
Article
Full-text available
Background: Perceptual congruence has been defined as the level of agreement between partners on various aspects of their shared lives, including perceived engagement in individual and jointly performed activities. While the level of adjustment made by partners to such activities is thought to contribute to a couple’s sense of mutuality, perception...
Article
Full-text available
Background Timely diagnosis and treatment are essential in the effective management of inflammatory rheumatic diseases (IRDs). Symptom checkers (SCs) promise to accelerate diagnosis, reduce misdiagnoses, and guide patients more effectively through the health care system. Although SCs are increasingly used, there exists little supporting evidence....
Article
Full-text available
This paper presents a novel urban transportation mode detection (TMD) method based on inertial and barometric data. To the best of our knowledge, this is the first time that a 3-axis accelerometer, a 3-axis gyroscope, and a barometer are combined for TMD purposes. One contribution was to build and share an optimized TMD dataset in terms of duration...
Article
Full-text available
The global COVID-19 pandemic has led to drastic changes in the management of patients with rheumatic diseases. Due to the imminent risk of infection, monitoring intervals of rheumatic patients have prolonged. The aim of this study is to present insights from patients, rheumatologists, and digital product developers on the ongoing digital health tra...
Article
Objective To evaluate the association between walking speed at self-selected comfort pace (Sfree), oxygen consumption at Sfree (VO2free), the oxygen cost of walking at Sfree (Cw), and mobility independence and independence for activities of daily living in post-stroke individuals. Design cross sectional study Setting hospital Participants All in...
Article
Full-text available
Walking while using a mobile phone has been shown to affect the walking dynamics of young adults. However, this has only been investigated using treadmill walking at a fixed walking speed. In this study, the dynamics of over ground walking were investigated using lower trunk acceleration measured over 12 consecutive trials, following differing walk...
Article
Full-text available
Background Self-tracking via wearable and mobile technologies is becoming an essential part of personal health management. At this point, however, little information is available to substantiate the validity and reliability of low-cost consumer-based hip and wrist activity monitors, with regard more specifically to the measurements of step counts a...
Article
Full-text available
Background Understanding the social mechanisms of the circadian rhythms of activity represents a major issue in better managing the mechanisms of age-related diseases occurring over time in the elderly population. The automated analysis of call detail records (CDRs) provided by modern phone technologies can help meet such an objective. At this stag...
Article
Full-text available
How circadian rhythms of activity manifest themselves in social life of humans remains one of the most intriguing questions in chronobiology and a major issue for personalized medicine. Over the past years, substantial advances have been made in understanding the personal nature and the robustness—i.e. the persistence—of the circadian rhythms of so...
Article
Full-text available
The aim of this study was (1) to evaluate the relative and absolute reliability of gait parameters during walking in single-and dual-task conditions in patients with axial spondyloarthritis (axSpA), (2) to evaluate the absolute and relative reliability of dual task effects (DTE) parameters, and (3) to determine the number of trials required to ensu...
Article
Full-text available
Introduction Work-related musculoskeletal disorders (WMSDs) are a growing worldwide burden and effective interventions to prevent them are needed. Physical activity at the workplace is now recognised as a relevant component of WMSDs prevention. Along these lines, warm-up interventions are now offered in a large number of companies to manage WMSDs....
Article
Objectives: Ankylosing spondylitis (AS) is a chronic rheumatic disease which affects the axial skeleton and sacroiliac joints. By impacting spinal mobility and physical functions, AS could also potentially impair gait. However, while published data are rather sparse, it appears that discrepancies exist regarding AS consequences on gait characteris...
Preprint
Full-text available
We present spread parameters for first and second waves of the COVID-19 pandemy for USA states, and third wave for 32 regions (19 countries and 13 states of the USA) detected beginning of August 2020. USA first/second wave spreads increase/decrease with population density, are uncorrelated with temperature and median population age. Pooling all 32...
Preprint
Full-text available
This description of contagiosity of SARS-COVID-19 third wave is currently submitted for publication. We post the preprint because of its potential importance for public health and decisions.
Article
Full-text available
1) Background: Here, we characterize COVID-19's waves, following a study presenting negative associations between first wave COVID-19 spread parameters and temperature. (2) Methods: Visual examinations of daily increases in confirmed COVID-19 cases in 124 countries, determined first and second waves in 28 countries. (3) Results: The first wave spre...
Article
Full-text available
Medical image segmentation is an important tool for current clinical applications. It is the backbone of numerous clinical diagnosis methods, oncological treatments and computer-integrated surgeries. A new class of machine learning algorithm, deep learning algorithms, outperforms the results of classical segmentation in terms of accuracy. However,...
Preprint
BACKGROUND Axial spondyloarthritis (axSpA) is a subgroup of inflammatory rheumatic diseases. Practicing regular exercise is critical to manage pain and stiffness, reduce disease activity, and improve physical functioning, spinal mobility, and cardiorespiratory function. Accordingly, monitoring physical activity and sedentary behavior in patients wi...
Article
Deep learning has gained a significant popularity in recent years thanks to its tremendous success across a wide range of relevant fields of applications, including medical image analysis domain in particular. Although convolutional neural networks (CNNs) based medical applications have been providing powerful solutions and revolutionizing medicine...
Preprint
BACKGROUND Understanding the social mechanisms of the circadian rhythms of activity represents a major issue in better managing the mechanisms of age-related diseases occurring over time in the elderly population. The automated analysis of call detail records (CDRs) provided by modern phone technologies can help meet such an objective. At this stag...
Preprint
Full-text available
(1) Background: Here, we characterize COVID-19 2nd waves, following a study presenting negative associations between 1st wave COVID-19 spread parameters and temperature; (2) Methods: Visual examinations of daily increase in confirmed COVID-19 cases in 124 countries, determined 1st and 2nd waves in 28 countries; (3) Results: 1st wave spread rate inc...
Preprint
BACKGROUND Interpersonal perception (IP) is defined as the reciprocal perceptions between two individuals and the degree of congruence between these perceptions. People in coupled relationships should develop accurate and prescient beliefs and perceptions about the other. So, understanding how each partner respectively perceives their level of inte...
Preprint
BACKGROUND Self-tracking via wearable and mobile technologies is becoming an essential part of personal health management. At this point, however, little information is available to substantiate the validity and reliability of low-cost consumer-based hip and wrist activity monitors, with regard more specifically to the measurements of step counts a...
Article
Full-text available
Introduction The ability to adapt dynamic balance to perturbations during gait deteriorates with age. To prevent age-related decline in adaptive control of dynamic balance, we must first understand how adaptive control of dynamic balance changes across the adult lifespan. We examined how adaptive control of the Margin of Stability (MoS) changes acr...