Nicolas Pierrel

Nicolas Pierrel
Lausanne University Hospital | CHUV · Anesthesia

About

11
Publications
7,052
Reads
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108
Citations
Citations since 2016
6 Research Items
28 Citations
20162017201820192020202120220123456
20162017201820192020202120220123456
20162017201820192020202120220123456
20162017201820192020202120220123456
Introduction
Skills and Expertise

Publications

Publications (11)
Conference Paper
Full-text available
Routine monitoring of blood pressure during general anesthesia relies on intermittent measurements with a non-invasive brachial cuff inflated every two to five minutes. While all these patients are equipped by a fingertip pulse oximeter, the acquired optical signals currently only provide SpO2 estimates. Our running clinical trial (NCT02651558) pre...
Conference Paper
Full-text available
Background and Goal of Study: Obtaining accurate continuous blood pressure (BP) monitoring is mandatory in critically-ill, anesthetized patients or during complex surgical procedures. The gold standard for continuous BP measurement invasive arterial catheter- is complex and associated with morbidity. To allow non-invasive beat-to-beat BP measuremen...
Conference Paper
Full-text available
Obtaining accurate continuous blood pressure monitoring is mandatory in critically-ill, anesthetized patients or during long and challenging surgical procedures. The gold standard for continuous BP measurement (invasive arterial catheter) is complex and associated with morbidity. This study presents a simple way to measure non-invasive BP continuo...
Conference Paper
Full-text available
Cuffless blood pressure monitoring at the chest requires accurate detection of the arrival time of arterial pressure pulses at chest skin. A clinical trial was designed (NCT02651558) in order to assess the performance of single-and multi-channel reflective PPG sensors when no pressure is applied onto optical probe. Experimental setup involved invas...
Conference Paper
Full-text available
The performance of estimating Systolic Blood Pressure (SBP) in anesthetized patients via Pulse Arrival Time (PAT) techniques was studied with respect to the minimum required time in between two recalibration procedures. Materials: a clinical trial [NCT02651558] involving 14 patients was conducted measuring PAT from an ECG and an arterial line inser...
Conference Paper
Full-text available
Routine monitoring of blood pressure during general anaesthesia relies on intermittent measurements with a non-invasive brachial cuff every five minutes. This manuscript provides first experimental evidence that a physiology-based pulse wave analysis algorithm applied to optical data (as provided by a standard fingertip pulse oximeter) is capable o...
Article
Because of the risk of vein collapse, the benefits of using a centrifugal pump to assist venous drainage for cardiopulmonary bypass are limited when the tips of peripheral cannulas are maintained within the vena cava. Using a mock circuit including 20 mm diameter latex tubing to mimic a vena cava, we compared the performance of 6 commercially avail...
Article
During cardiopulmonary bypass, the perfusionist maintains physiological parameters laid down in protocols; this is his or her performance capability. In order to assess his or her performance we need to be able to analyse these physiological parameters objectively. We defined six parameters, pH, BE, PaCO2, PaO2, ACT and oesophageal temperature and...
Article
Protamine sulphate is routinely used after cardiopulmonary bypass (CPB) to restore the patient’s baseline coagulatory state. However, adverse reactions are encountered, and alternative means to neutralize heparin are, therefore, necessary. The Heparin Removal Device (HRD) constitutes an extracorporeal circuit that allows ex vivo deheparinization by...
Article
Full-text available
Reduction of priming volumes of the cardiopulmonary bypass (CPB) circuit in neonatal cardiac surgery to decrease haemodilution and blood transfusion requirements can be achieved with the use of neonatal low prime oxygenators and smaller diameter tubing. We have further reduced our prime volume with the use of a custom-designed arm allowing for remo...
Article
Minimally invasive open heart surgery involves limited intrathoracic cannulation sites necessitating cardiopulmonary bypass to be initiated via peripheral access using percutaneous cannulae with the tip placed into the right atrial cavity. However, surgery involving the opening of the right heart obliges the surgeon to maintain the end of the cannu...

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