Nicolas Dugré

Université de Montréal | UdeM · Faculty of Pharmacy

Background In recent years, there has been growing interest in studying asthma treatment escalation patterns in the real-world setting, particularly with the advent of expensive biologic therapies. Healthcare administrative claims databases can be used to study treatment escalation patterns at a population-level; however, the reported definitions f...

Objective: To determine the proportion of patients with neuropathic pain who achieve a clinically meaningful improvement in their pain with the use of different pharmacologic and nonpharmacologic treatments. Data sources: MEDLINE, EMBASE, the Cochrane Library, and a gray literature search. Study selection: Randomized controlled trials that rep...

In the SImplification of Medications Prescribed to Long-tErm care Residents (SIMPLER) cluster-randomized controlled trial, we investigated the impact of a structured medication regimen simplification intervention on medication incidents in residential aged care facilities (RACFs) over a 12-month follow-up. A clinical pharmacist applied the validate...

Objective: To determine the proportion of chronic low back pain patients who achieve a clinically meaningful response from different pharmacologic and nonpharmacologic treatments. Data sources: MEDLINE, EMBASE, Cochrane Library, and gray literature search. Study selection: Published randomized controlled trials (RCTs) that reported a responder...

Background: Skeletal muscle cramps are common and often occur in association with pregnancy, advanced age, exercise or motor neuron disorders (such as amyotrophic lateral sclerosis). Typically, such cramps have no obvious underlying pathology, and so are termed idiopathic. Magnesium supplements are marketed for the prophylaxis of cramps but the ef...

Objective: To determine the effect of mask use on viral respiratory infection risk. Data sources: MEDLINE and the Cochrane Library. Study selection: Randomized controlled trials (RCTs) included in at least 1 published systematic review comparing the use of masks with a control group, either in community or health care settings, on the risk of...

Objective: To determine how many patients with chronic osteoarthritis pain respond to various non-surgical treatments. Data sources: PubMed and the Cochrane Library. Study selection: Published systematic reviews of randomized controlled trials (RCTs) that included meta-analysis of responder outcomes for at least 1 of the following intervention...

What is known and objective: Pharmacists' responsibilities and practices have expanded over the years to be more clinical. Working in other settings and collaborating with other healthcare professionals can lead to new needs that are unmet by actual training. This study was performed to describe the characteristics and practices of pharmacists wor...

A needs assessment study of pharmacists working in family medicine groups (FMG) demonstrated the necessity to build a practice-based network. This network would foster a faster integration into FMG and a more efficient collaborative practice. It would also take advantage of an existing practice-based research network (PBRN)—the STAT (Soutien Techno...

Objective: To use the best available evidence and principles of shared, informed decision making to develop a clinical practice guideline for a simplified approach to managing opioid use disorder (OUD) in primary care. Methods: Eleven health care and allied health professionals representing various practice settings, professions, and locations c...

Objective: To summarize the best available evidence regarding various topics related to primary care management of opioid use disorder (OUD). Data sources: MEDLINE, Cochrane Library, Google, and the references of included studies and relevant guidelines. Study selection: Published systematic reviews and newer randomized controlled trials from...