Nico Verdonschot

Radboud University Medical Centre (Radboudumc) · orthopedics

The fixation of press-fit orthopaedic devices depends on the mechanical properties of the bone that is in contact with the implants. During the press-fit implantation, bone is compacted and permanently deformed, finally resulting in the mechanical interlock between implant and bone. For the development and design of new devices, it is imperative to...

Cementless femoral total knee arthroplasty (TKA) components use a press-fit (referred to as interference fit) to achieve initial fixation. A higher interference fit could lead to a superior fixation, but it could also introduce more damage to the bone during implantation. The purpose of the current study was to investigate the effect of interferenc...

Introduction: Cyclic strain is well known to affect cell behavior. It is also known that isotropic and anisotropic strain can affect cells differently[1]. While in-vivo cells experience varying degrees of anisotropy (d.o.a.), in-vitro anisotropic strain studies have mostly focused on uniaxial strains. In order to create a better understanding of ce...

Background Context. PSO can restore balance in Kyphotic deformities. Effect on central canal seems unknown. Purpose To measure shortening of canal in PSO as side effect.. Study design : Radiographic study of the canal-shortening effect as feature of a wedge or PSO the TL- spine. A case series with emphasis on radiographic alterations of the canal a...

In this chapter various aspects of cemented stem designs such as shape, surface roughness and material properties are discussed. An attempt is made to provide some guidelines of design features, or combinations of them, that are known to lead to early failure. A design philosophy can be regarded as a good (or optimal) combination of design features...

Samples of plain and vancomycin-tobramycin loaded low viscosity cements were evaluated for their tensile mechanical properties. Vancomycin is effective against nearly all resistant pathogens now involved in prosthesis infection. The mechanical properties of vancomycin-impregnated cement have never been studied. Tobramycin extends the spectrum to Gr...