Ngozi Lillian Umedum

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• Doctor of Philosophy
• Lecturer at Nnamdi Azikiwe University

Protein tyrosine phosphatase 1B (PTP1B) has been identified as a promising drug target for the development of diabetes medications via an inhibition mechanism. Using a computational approach, this study investigates the binding mechanism of lead optimized natural compounds from Allium sativum against the human PTP1B. The molecular docking, induced-...

Malaria control efforts have been hampered due to the emergence of resistant malaria parasite strains and the coinciding events of Covid-19. The quest for more effective and safe treatment alternatives is driving a slew of new studies that must be accelerated if malaria can be overcome. Due to its reported antimalarial activity, we studied the effe...

Diabetes has increased radically in recent decades globally. Diabetes mainly emerged as a major health care problem in the world, among which type-2 diabetes is the most common. Protein tyrosine phosphatase 1B (PTP1B) is an important target for treating type-2 diabetes. Discovering new and effective treatment options for type-2 diabetes is currentl...

Aim: Justicia carnea has been used in traditional medicine in Nigeria in the treatment and management of various diseases which include inflammation, cancer, malaria, sickle cell disease, gastrointestinal infections, anemia, HIV, diabetes, diarrhea, typhoid, liver diseases, hepatitis, cough, etc. This review is aimed at checking the relationship be...

Aim: To compare the phytochemicals and anti bacterial activities of leaf, stem and root extracts of Spathodea companulata. Methodology: The leaf, stem and root of Spathodea companulata were collected, washed, air-dried, ground and each extracted with water, methanol, ethyl acetate and n-hexane. The extracts were analysed for the presence of phytoch...

Aim: To compare the phytochemicals and antioxidant activities of stem bark and root extracts of Annona muricata. Methodology: The stem bark and root of Annona muricata were collected, washed, air-dried, ground and each extracted with methanol, ethyl acetate and n-hexane. The extracts were analysed for the presence of phytochemicals. Antioxidant scr...

This analysis was carried out to identify and compare the phytochemicals present in the n-hexane, methanol and ethyl acetate extracts of the leaves of Bridelia micrantha, Cassytha filiformis, Euphorbia hirta and Securinega virosa and their antimicrobial activities. The results showed presence of saponin, flavonoids, alkaloids, tannin and phenolics...

The problems of environmental pollution by heavy metals have been on global discuss and clean up costs have consumed billions of dollars using current engineering technology. A cost-effective, noninvasive ‗green' technology alternative that utilizes plants to accumulate, translocate, and concentrate high amount of these heavy metals-phytoremediatio...

The effect of anthropogenic activity relating to industrial and economic development has had a detrimental impact on the environment and human health, and hence the need for continued research. Five common African vegetables—Murraya koenigii , Ocimum gratissimum, Amaranthus hybridus , Capsicum annuum and Moringa oleifera were used to study absorpti...

Solving the problem of heavy metal pollution and its effects on the biota have remained a frontline issue in the public health matters of developing , and even the developed countries. Non-edible African plants-Dieffenbachia bownanii and Eleusine indica-were used to study the absorption of Cadmium, Lead Zinc and Cobalt from soils inoculated with th...

Forty two different cosmetic samples consisting of 16 facial cosmetics, 6 soaps, 1 shower gel, 12 emulsions, 2 underarm cosmetics, 3 nail cosmetics and 2 perfumes were purchased from department stores and cosmetic shops within Onitsha Main Market and Eke-Awka in Anambra, Nigeria. Seven of these cosmetic (16.67%) were locally manufactured in Nigeria...

Timber has always played an influencing role in the lives of humans. At high temperature and in the presence of air, it burns or decomposes exothermically. The flame characteristics studied were the ignition time, flame duration, flame propagation rate and after-glow time. Wet and oven-dry densities, moisture content and porosity index of these tim...

Wood is a heterogeneous, hygroscopic, cellular and anisotropic material of biological origin. The properties of wood that make it an ideal raw material for several purposes are mainly determined by the specific architecture of the cell walls. Moisture content, porosity and water imbitition capacity contribute to the quality of timber. The examinati...

Effects of flame propagation rate and oven dry density on flame propagation rate of fifty two selected Nigeria timbers were analyzed. The results showed that timbers with least and highest flame propagation rates (FPR) were Erythrophleum ivorense (0.008cmS-1) and Protea elliottii (0.29cmS-1) respectively. Some timbers had equal flame propagation ra...

Effects of ignition time on fifty two selected Nigerian timbers were analyzed in other to note the time for each wood's combustion. Fifty- two (52) timber samples were collected from fourteen States in Nigeria namely Anambra, Enugu, Ebonyi, Imo, Delta, Edo, Cross River, Akwa Ibom, Abia, Oyo, Lagos, Kano, Sokoto and Rivers State.The timber samples w...

Aims: To review the phytochemical composition, medicinal uses and pharmacological properties of different parts of the plant, Hyptis suaveolens. Methodology: Detailed data were collected from studies carried out by several researchers on the use of different parts of the plant so as to authenticate the claims by traditional healers in some parts of...

The thermal and pharmaceutical properties of Anogeissus leiocarpus timber were investigated. Various variable and thermal analysis performed on the timber; oven dry density, water imbibitions (at different intervals: 30 mins, 5 hrs & 24 hrs), thermal conductivity, electrical conductivity, afterglow time, flame duration, flame propagation rate, igni...

The effect of oven dry density on thermal conductivity of fifty-two selected Nigerian timbers was analyzed. The results showed that C. vogelli and G. arborea with thermal conductivity of 10.06 × 102 μmoh/cm recorded ODDs of 36.6 ×10-2g.cm-3 and 40.3 ×10-2g.cm-3 respectively; G. kola and C. barteri with thermal conductivity of 10.92 ×10-2 μmoh/cm ha...