Nermin Karaosmanoğlu

• Doctor of Medicine
• Specialist on dermatology at T.C. Sağlık Bakanlığı Ankara Eğitim ve Araştırma Hastanesi

Background Isotretinoin is frequently used for treating severe, treatment-resistant, and scarring acne. A wide range of musculoskeletal side effects are reported due to isotretinoin, and one of them is enthesopathy. Objectives In this study, we used ultrasound to evaluate tendon thickness and the presence of enthesophytes, erosions, calcifications...

Introduction: Acne vulgaris (AV) is one of the most common skin disorders, particularly affecting young people and adolescents, who are also widespread users of social media. Objectives: The objectives of this study are to understand why patients seek information about their acne from social media, their perspectives on dermatologists and social me...

Aim: The aim of this study is to analyze the clinical and demographic characteristics, histopathological findings, and treatment responses of patients with pityriasis lichenoides. Additionally, the study aims to investigate the differences between pediatric and adult patients. Material and Method: The data of 47 patients with pityriasis lichenoides...

Corresponding author: İçim Kömürcügil

Background Pityriasis rubra pilaris (PRP) is a rare papulosquamous disease with a characteristic clinical appearance, including follicular salmon-coloured papules, which can sometimes progress into erythroderma. Both clinical and histopathological findings are important in diagnosing the disease and should be evaluated together. Objectives There a...

Ankara Eğitim ve Araştırma Hastanesi Deri ve Zührevi Hastalıkları Kliniği, Ankara, Türkiye ÖZET Amaç: Bu çalışmanın amacı, psoriazis (PsO) tanılı çocukların sos-yodemografik ve klinik özelliklerini değerlendirmek ve bu özelliklerin has-talık şiddetiyle ilişkisini belirlemektir. Gereç ve Yöntemler: Bu çalışma retrospektif kesitsel bir araştırmadır....

Aim: The loss of smell is a common disease and can affect a patient’s quality of life. Olfactory disturbance leads to problems such as safety and eating. Acne vulgaris is a prevalent disease in the daily clinical practice of a dermatologist. Doxycycline and isotretinoin are the most preferred systemic drugs for severe acne. This study aimed to inve...

Current evidence indicates that obesity may initiate psoriasis or worsen existing disease. Various factors contribute to the development of obesity, including eating disorders (EDs). The aim of this study was to screen for and identify factors associated with EDs in patients with psoriasis and their impact on the development of obesity in this popu...

ÖZET Amaç: Bu çalışmanın amacı, erken evre Mikozis fungoides (MF) nedeniyle darband ultraviyole B (dbUVB) fototerapisi alan hastaların demografik özellikleri, hastalık yaygınlıkları, histopatolojik bulguları, fototerapi tedavi verileri ve yanıtlarının incelenmesidir. Gereç ve yöntem: Bu çalışmaya Şubat 2020 ile Şubat 2024 yılları arasında üçüncü ba...

In this study, it was aimed to describe isotretinoin-induced nail changes and increase patients’ treatment compliance. A total of 200 patients diagnosed with acne vulgaris were included in the study. 100 of the patients were started systemic isotretinoin treatment and 100 control patients were receiving topical acne treatment. Age and gender of all...

Pruritus is a common complaint in dermatology outpatient clinics. It is defined as chronic pruritus if the symptoms last 6 weeks or longer. Fibromyalgia is a chronic, extensive pain syndrome that is well-known for its clinical signs, such as exhaustion, sleeping disorders, and some other pain symptoms. In the present study, it was investigated whet...

Introduction Alopecia areata is a type of non-scarring alopecia which is thought to be associated with T-cell mediated immune response. Objective This study aimed to compare the levels of serum inflammatory markers before and after treatment in patients with alopecia areata. The study explored the utility of the systemic immune-inflammation index...

Background Masseter muscle hypertrophy is characterized by a symmetrical or asymmetrical increase in muscle volume. Although it can be asymptomatic, it may be associated with bruxism. Therefore, patients may seek intervention for esthetic and/or functional concerns. This study aimed to establish patient characteristics, purpose of undergoing botuli...

In this study, we aimed to describe isotretinoin-induced nail changes and to increase patients' compliance with treatment. A total of 200 patients diagnosed with acne vulgaris were included in the study, including 100 patients who started systemic isotretinoin treatment and 100 control patients who received topical acne treatment. The patients age,...

Background: Isotretinoin is used to treat severe acne, treatment-resistant moderate acne, and acne that leads to scarring or psychological distress. It has many side effects and is also associated with depression, sleep apnea, and sleep disturbances. Objectives: In this study, we aimed to evaluate the effects of isotretinoin on depression, sleep...

Background: Both the skin and neuronal systems originate from the ectoderm. In patients hospitalized for neurosurgery, their skin may be affected by genetic and environmental factors. Objective: This study researched disease relationships by evaluating the profile of hospitalized neurosurgery patients who consulted with dermatology in a tertiary c...

Introduction Melanocyte dysfunction in vitiligo is considered to be due to genetics, inflammation, and autoimmunity. Research has shown that oxidative stress plays a significant role in triggering these conditions. Currently, there are several markers indicating hematological inflammation and oxidative stress. This study aimed to investigate the st...

Aim: Botulinum toxin type A (BTX-A) treatment for facial rejuvenation has been started to used widely and become the most common aesthetic procedure. The aim in this study to evaluate the patients features and outcomes who had Onabotulinumtoxin A. Material and Method: The data of the BTX-A patient’s gender, age, occupation, history of cosmetic proc...

Background: Genital dermatoses contain a group of diseases that affect the skin of the genital area. Genital dermatoses are classified as venereal and nonvenereal. They can affect a patient’s life quality and can cause depression, anxiety and stress. Aims: This study aimed to evaluate and compare the quality of life index, depression, stress and...

Brunsting-Perry pemphigoid (BPP) is a variant of cicatricial pemphigoid characterised by tense, pruritic subepidermal bullae which eventually heals with atophic scarring. BPP has a predilection for head and neck area with little or no mucosal involvement. Average age of onset is 58 with a 2:1 male/female ratio. Here, we report a

Rosacea is a chronic inflammatory skin disease that is characterized by recurrent episodes of erythema, telangiectasia and papulopustular lesions. Although the pathogenesis is not well established, growing knowledge suggests that multiple etiological factors play a role resulting in inflammation. The aim of the present study is to investigate infla...

Background: Eyebrow region is a dynamic region, and it has a thinner skin prone to wrinkles and sagging. Descended brows could be repositioned immediately with fewer complications by the use of the threads. Despite all its advantages, the main drawback of absorbable thread lift is its short duration of lifting effect. Aims: This report aims to d...

Introduction: Due to the increase in COVID-19 patients during the pandemic, the workload of emergency departments has increased. The profile of patients seeking non-COVID medical care has changed significantly because of the pandemic; this includes dermatological emergencies. Objective: The aim was to evaluate and compare adult dermatological em...

Aim Several studies were conducted to determine the characteristics of hospitalized patients with Herpes Zoster. This study aimed to evaluate the characteristics of hospitalized especially elderly patients with Herpes Zoster and compare them with young adult patients in tertiary clinic in Turkey. Material and Methods Hospitalized HZ patients were e...

Background and Design: Demodex, a mite, is known to influence the etiopathogenesis of rosacea, pityriasis folliculorum, pustular folliculitis, perioral granulomatous dermatitis, hyperpigmented patch, and chronic blepharitis. This study aimed to investigate the relationship between Demodex, which is increasingly important in the pathogenesis of rosa...

Coronavirus disease 2019 (COVID-19) is caused by Severe Acute Respiratory Syndrome- Coronavirus-2 (SARS-CoV-2) and has affected millions of individuals. Here, we report the case of a 57-year-old man, who had COVID-19 infection and was treated with favipravir. He came to our clinic with erosions in oral and anogenital region.

Background Musculoskeletal side effects related to isotretinoin are frequently reported. This study aimed to investigate the effect of oral isotretinoin treatment on muscle strength. Our second aim was to evaluate whether there was a correlation between the serum creatine phosphokinase (CPK) level, a specific marker of muscle breakdown, and muscle...

Background/ objectives: Acne vulgaris is a chronic inflammatory disease affecting the pilosebaceous unit. Isotretinoin is an effective treatment option for severe acne. The aim of this study was to evaluate musculoskeletal side effects of systemic isotretinoin treatment. Methods: Ninety-four patients with acne vulgaris and 100 sex- and age-match...

Background: Narrowband ultraviolet B (NB-UVB) phototherapy has become a widely used, standard treatment modality in dermatology. The effect of 8-methoxypsoralen plus ultraviolet A on antinuclear antibody (ANA) formation has been investigated extensively, but there are very scarce data about the potential risk of NB-UVB phototherapy inducing product...

Background Narrowband ultraviolet B (NB‐UVB) phototherapy has become a widely used, standard treatment modality in dermatology. The effect of 8‐methoxypsoralen plus ultraviolet A on antinuclear antibody (ANA) formation has been investigated extensively, but there are very scarce data about the potential risk of NB‐UVB phototherapy inducing producti...

Rosacea is an inflammatory skin disease with a chronic course. Although the pathogenesis of rosacea is not completely understood, it is regarded as an inflammatory process. The aim of the present study was to evaluate uric acid (UA) levels in patients with rosacea and to detect the correlation of UA levels with disease activity. A total of 61 patie...

Narrow-band ultraviolet B (NB-UVB) phototherapy is an effective and widely used treatment modality for psoriasis and other inflammatory skin diseases. The carcinogenic effect of PUVA treatment has been investigated extensively, but there is very scarce data about the role of NB-UVB in the development of skin cancer. The aim of this study was to inv...

Background A chin that is of right size, shape, and contour plays a crucial role in overall facial balance and esthetically harmonious appearance. Dermal fillers have been widely used for correcting mild to moderate chin retrusion and resorption. Aims The aim of this study was to share our preferential technique for chin augmentation and to evalua...

Background Hyaluronic acid (HA) fillers have been widely used for reversing the signs of the aging face. Injectable fillers are particularly effective in treating vertical glabellar wrinkles. Aims The aim of this study was to share our own safe glabella filling technique and to evaluate our results in 50 patients with facial rejuvenation. Methods...

Isotretinoin (ISO) is a drug which is used for the treatment of severe and refractory acne vulgaris (AV), over the last few decades. The drug has various musculoskeletal side effects. The aim of this study was to investigate relationship between serum 25 hydroxy (OH) vitamin D levels and the ISO-induced musculoskeletal side effects in patients with...

p class="abstract"> Background: In this study, we aimed to evaluate the response of patient treated with omalizumab at certain time intervals through 6 months with pruritus visual analog scale, urticaria activity score and quality of life indexes. Methods: The study was performed on ten patients diagnosed with chronic idiopathic spontaneous urticar...

Introduction: Chronic spontaneous urticaria (CSU) which develops without a known stimulation is defined as the occurrence of spontaneous wheals, angioedema or both for longer than six weeks. Infections, autoimmunity, food intolerance and internal parasitic infections are supposed to be underlying causes of CSU. The aim of this study was to evaluat...

INTRODUCTION: Autoimmune bullous diseases are a rare group of diseases characterized by the formation of autoantibodies against various autoantigens foundin the tissue and serum, affecting the skin and mucous membranes.The aim of this study was to evaluate the demographical and clinical features of patients with autoimmune bullous diseases who appl...

INTRODUCTION: To evaluate whether there is a relationship between androgenetic alopecia (AGA) severity and body mass index (BMI). MATERIAL AND METHODS: A total of 132 male patients with AGA who were admitted to the Dermatology Clinic of the University of Health Sciences Ankara Training and Research Hospital were included in this study. The patients...

Background and Design: Current studies link a possible relationship between vitamin D deficiency and many autoimmune diseases. Alopecia areata(AA) is a frequent autoimmune dermatological disease. The aim of this study was to investigate the relationship between vitamin D levels and alopecia areata; a frequent autoimmune dermatological disease. Mat...

Tularemia is a zoonotic infection caused by Francisella tularensis. Oropharyngeal tularemia is the most common form of disease in our country, which spreads by intake of contaminated water or food. We presented 3 oropharengeal tularemia cases with cutaneous signs. The patients with oral and/or pharangeal ulcers or sore throat, especially when the d...

Ramsay-Hunt Syndrome (RHS) is a rare disease characterized by peripheral facial paralysis, cochleovestibular symptoms, skin lesions in the auricular canal and/or in the auricula and rarely skin lesions in the hard palate. The disease is also known as Herpes zoster oticus or herpes zoster cephalicus. Early diagnosis and antiviral treatment of periph...

Background Acne vulgaris is a chronic inflammatory disease that usually requires systemic treatment for severe forms. Isotretinoin is the most effective drug in the treatment of acne vulgaris. In this study, we aimed to compare the efficacies of intermittent and continuous low-dose isotretinoin regimens in the treatment of moderate acne vulgaris. M...

Linear Ig A bullous dermatosis (LABD) is an acquired autoimmune subepidermal blistering disorder with linear deposits of IgA along the basement membrane zone. Its cause is unclear, although it appears to have an immune-mediated basis. Idiopathic, systemic disorder-related, and rarely drug-induced forms of LABD have been described. We describe a cas...