Nerea González-García

University of Salamanca · Department of Statistics

Treatment-emergent sexual dysfunction (TESD) is one of the most frequent and persistent adverse effects of antidepressant medication. Sexual dysfunction (SD) secondary to SSRIs occurs in >60% of sexually active patients and >80% of healthy volunteers, with this causing treatment discontinuation in >35% of patients. However, this factor is rarely ad...

Treatment-emergent sexual dysfunction (TESD) is one of the most frequent and persistent adverse effects of antidepressant medication. Sexual dysfunction (SD) secondary to SSRIs occurs in >60% of sexually active patients and >80% of healthy volunteers, with this causing treatment discontinuation in >35% of patients. However, this factor is rarely ad...

The aim of this paper is to analyze the main coping strategies used by frontline teams during the first days of the COVID pandemic confinement in Spain. This information could be necessary in order to carry out training programs that allow a better handling of future emergency situations, as well as acting more effectively and with less negative em...

Objectives The estimates of biological variation (BV) have traditionally been determined using direct methods, which present limitations. In response to this issue, two papers have been published addressing these limitations by employing indirect methods. Here, we present a new procedure, based on indirect methods that analyses data collected withi...

HJ-Biplot analysis is a multivariate graphic representation that collects data covariation structure between variables and individuals to represent them in a low-dimensional space with the highest quality in the same reference system. Consequently, it is a promising technique for evaluating dietary exposure to polyphenols and accurately characteriz...

In 2015, the United Nations and various countries committed to achieving the Sustainable Development Goals. The 17 goals revolve around 3 main axes: eradicating poverty, protecting the planet, and ensuring peace and prosperity for all people by 2030. These goals are integrated so that interventions in one area inevitably affect the others. Undoubte...

The molecular complexity displayed in acute myeloid leukemia (AML) hinders patient stratification and treatment decisions. Previous studies support the utility of using specific gene panels for this purpose. Focusing on two salient features of AML, the production of reactive oxygen species (ROS) by NADPH oxidases (NOX) and metabolism, we aimed to i...

In this work, a new mathematical algorithm for sparse and orthogonal constrained biplots, called C enet Biplots, is proposed. Biplots provide a joint representation of observations and variables of a multidimensional matrix in the same reference system. In this subspace the relationships between them can be interpreted in terms of geometric element...

Diagnosis and classification of gliomas mostly relies on histopathology and a few genetic markers. Here we interrogated microarray gene expression profiles (GEP) of 268 diffuse astrocytic gliomas—33 diffuse astrocytomas (DA), 52 anaplastic astrocytomas (AA) and 183 primary glioblastoma (GBM)—based on multivariate analysis, to identify discriminator...

Background: The prognostic impact of the expression profile of genes recurrently amplified in glioblastoma multiforme (GBM) remains controversial. Methods: We investigated the RNA gene expression profile of epidermal growth factor receptor (EGFR), cyclin-dependent kinase 4 (CDK4), murine doble minute 4 (MDM4), and platelet derived growth factor...

Despite being clinically underestimated, sexual dysfunction (SD) is one of the most frequent and lasting adverse effects associated with antidepressants. Desvenlafaxine is an antidepressant (AD) with noradrenergic and serotonergic action that can cause a lower SD than other serotonergic ADs although there are still few studies on this subject. Obj...

e18266 Background: Patients with cancer and their caregivers express unmet needs beyond the clinical approach to cancer. The ECO Foundation (Quality and Excellence in Oncology) and the Spanish Association Against Cancer (AECC) have promoted a qualitative research study with the objective to compare the perceptions of newly diagnosed and 2-3 years a...

The objective of this cross-sectional study was to evaluate the frequency, impact, and management of sexual dysfunction associated with commonly prescribed antidepressants available in psychiatry outpatient clinics in Spain. We recruited 2163 adult patients who had undergone treatment with antidepressants for at least 8 weeks and had a history of n...

The influence of different approaches and attitude towards learning in the General Didactics is studied in few investigations. The main objective of this work is to describe in a multivariate way the relationships between attitude towards General Didactics and learning approaches of students majoring in Social Learning of the University of Salamanc...

Background: Patients with cancer and their caregivers express unmet needs beyond the clinical approach to cancer. The ECO Foundation (Quality and Excellence in Oncology) and the Spanish Association Against Cancer (AECC) have promoted a qualitative research study with the objective to identify and compare the perceptions of newly diagnosed and 2–3 y...

This study examined whether methadone (hereinafter referred to as MTD) maintenance treatment (MMT) is correlated with sexual dysfunction (SD) in heroin-dependent men. This was conducted to determine the prevalence of sexual dysfunction and if there is a relationship between duration and dose among men on MMT and its impact on the quality of life. T...

Resumen Pocos estudios investigan la influencia de la actitud y enfoques de aprendizaje en la Didáctica General. El objetivo principal de este trabajo consiste en describir, en un sentido multivariante, las relaciones entre la actitud hacia la Didáctica General y los enfoques de aprendizaje de estudiantes del grado de Educación Social de la Univers...

CUR decomposition is one of the matrix decomposition techniques proposed in the literature for the selection of rows and/or columns of a data matrix. Dynamic CUR is proposed as an alternative to the selection criteria of the CUR decomposition based on probabilistic criteria. This alternative tries to fit the most adequate theoretical probability di...

Background: One of the most important concepts within Cognitive Social Theory as framed by Bandura is the perceived self-efficacy; this concept became widespread in 1981 when Mathias Jerusalem and Ralf Schwarzer, using 10 items, established a one-dimensional and universal construct of this scale. The main purpose of this study is to show that the...

Estudio descriptivo observacional transversal en una muestra de 60 casos de niño/as y adolescentes que realizan tratamiento antipsicótico. Se realiza una determinación analítica donde se objetivan los niveles de prolactina y se determinan la relación entre esos niveles de prolactina y los posibles efectos secundarios causados. Los resultados pueden...

[ES]El Análisis de Componentes principales es una de las técnicas más implementada en las etapas de pre-procesamiento o de reducción de la dimensión de matrices de datos. Su principal función es proyectar los datos de entrada en nuevas direcciones, conocidas como componentes principales (PCs), que absorban la mayor cantidad de información posible y...